Expression and G-protein coupling of μ-opioid receptors in the spinal cord and dorsal root ganglia of polyarthritic rats

Neuropeptides

Volumn 37, Issue 4, 2003, Pages 211-219

  Ballet, S ^a   Conrath, M ^b   Fischer, J ^b   Kaneko, T ^c   Hamon, M ^a   Cesselin, F ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b CNRS   (France)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Dorsal root ganglia; Immunohistochemistry; Polyarthritis; Spinal cord; 35S GTP S autoradiography; opioid receptor

Indexed keywords

ANTIBODY; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLORNITHYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FREUND ADJUVANT; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; NALOXONE; PENTOBARBITAL;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; AUTORADIOGRAPHY; CHRONIC PAIN; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; LITERATURE; LUMBAR SPINAL CORD; MALE; NERVE FIBER TRANSPORT; NONHUMAN; POLYARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUBLICATION; QUANTITATIVE ANALYSIS; RAT; RECEPTOR DENSITY; SENSORY NERVE; SENSORY NERVE CELL; SPINAL CORD; SPINAL CORD DORSAL HORN; SPINAL GANGLION; STATISTICAL SIGNIFICANCE; UPREGULATION;

EID: 0041379899     PISSN: 01434179     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0143-4179(03)00045-3     Document Type: Article

References (46)

1. Abbadie, C., Pan, Y.X., Pasternak, G.W., 2000. Differential distribution of μ opioid receptor carboxy terminal splice variants MOR-1C-like and MOR-1-like immunoreactivity: evidence for region-specific processing. J. Comp. Neurol. 419, 244-256.
2. Arvidsson, U., Riedl, M., Chakrabarti, S., Lee, J.H., Nakano, A.H., Dado, R.J., Loh, H.H., Law, P.Y., Wessendorf, M.W., Elde, R., 1995. Distribution and targeting of μ-opioid receptor (MOR1) in brain and spinal cord. J. Neurosci. 15, 3328-3341.
3. Atweh, S.F., Kuhar, M.J., 1977. Autoradiographic localization of opiate receptors in rat brain. I - Spinal cord and lower medulla. Brain Res. 124, 53-67.
4. Ballet, S., Mauborgne, A., Benoliel, J.J., Bourgoin, S., Hamon, M., Cesselin, F., Collin, E., 1998. Polyarthritis-associated changes in the opioid control of spinal CGRP release in the rat. Brain Res. 796, 198-208.
5. Besse, D., Lombard, M.C., Zajac, J.M., Roques, B.P., Besson, J.M., 1990. Pre- and post-synaptic distribution of μ, δ and κ opioid receptors in the superficial layers of the dorsal horn of the rat spinal cord. Brain Res. 521, 15-22.
6. Besson, J.M., Guilbaud, G. (Eds.), 1988. The Arthritic Rat as a Model of Clinical Pain? Excerpta Medica. Elsevier, Amsterdam, p. 257.
7. Braz, J., Beaufour, C., Coutaux, A., Epstein, A.L., Cesselin, F., Hamon, M., Pohl, M., 2001. Therapeutic efficacy in experimental polyarthritis of viral-driven enkephalin overproduction in sensory neurons. J. Neurosci. 21, 7881-7888.
8. Calvino, B., Crépon-Bernard, M.O., Le Bars, D., 1987. Parallel clinical and behavioural studies of adjuvant-induced arthritis in the rat: possible relationship with "chronic pain". Behav. Brain Res. 24, 11-29.
9. Cesselin, F., Benoliel, J.J., Bourgoin, S., Collin, E., Pohl, M., Hamon, M., 1999. Spinal mechanisms of opioid analgesia. In: Stein, C. (Ed.), Opioid in Pain Control. Basic and Clinical Aspects. Cambridge University Press, Cambridge, pp. 70-95.
10. Cesselin, F., Montastruc, J.L., Gros, C., Bourgoin, S., Hamon, M., 1980. Met-enkephalin levels and opiate receptors in the spinal cord of chronic suffering rats. Brain Res. 191, 25-31.
11. χi3. J. Neurochem. 74, 1068-1078.
12. Chen, Y., Mestek, A., Liu, J., Hurley, J.A., Yu, L., 1993. Molecular cloning and functional expression of a μ-opioid receptor from rat brain. Mol. Pharmacol. 44, 8-12.
13. 5-enkephalin. Brain Res. 731, 141-154.
14. Danner, S., Lohse, M.J., 1996. Phosducin is a ubiquitous G-protein regulator. Proc. Natl. Acad. Sci. USA 93, 10145-10150.
15. Delay-Goyet, P., Kayser, V., Zajac, J.M., Guilbaud, G., Besson, J.M., Roques, B.P., 1989. Lack of significant changes in μ, δ opioid binding sites and neutral endopeptidase EC3.4.24.11 in the brain and spinal cord of arthritic rats. Neuropharmacology 28, 1341-1348.
16. Dhawan, B.N., Cesselin, F., Raghubir, R., Reisine, T., Bradley, P.B., Portoghese, P.S., Hamon, M., 1996. International Union of Pharmacology - XII - Classification of opioid receptors. Pharmacol. Rev. 48, 567-592.
17. Ding, Y.Q., Kaneko, T., Nomura, S., Mizuno, N., 1996. Immunohistochemical localization of μ-opioid receptors in the central nervous system of the rat. J. Comp. Neurol. 367, 375-402.
18. Garzon, J., Rodriguez-Diaz, M., Lopez-Fando, A., Sanchez-Blazquez, P., 2001. RGS9 proteins facilitate acute tolerance to μ-opioid effects. Eur. J. Neurosci. 13, 801-811.
19. Gouret, C., Mocquet, G., Tegner, R., 1976. Use of Freund's adjuvant arthritis in anti-inflammatory drug screening in the rat: value of animal selection and preparation in breeding center. Lab. Anim. Sci. 26, 281-287.
20. Hassan, A.H.S., Ableitner, A., Stein, C., Herz, A., 1993. Inflammation of the rat paw enhances axonal transport of opioid receptors in the sciatic nerve and increases their density in the inflamed tissue. Neuroscience 55, 185-195.
21. Hylden, J.L.K., Thomas, D.A., Iadarola, M.J., Nahin, R.L., Dubner, R., 1991. Spinal opioid analgesic effects are enhanced in a model of unilateral inflammation/hyperalgesia: possible involvement of noradrenergic mechanisms. Eur. J. Pharmacol. 194, 135-143.
22. IASP, 1983. Ethical standards for investigations on experimental pain in animals. Pain 16, 109-110.
23. Ji, R.R., Zhang, Q., Law, P.Y., Low, H.H., Elde, R., Hökfelt, T., 1995. Expression of μ-, δ- and κ-opioid receptor-like immunoreactivities in rat dorsal root ganglia after carrageenan-induced inflammation. J. Neurosci. 15, 8156-8166.
24. Kaneko, T., Minami, M., Satoh, M., Mizuno, N., 1995. Immunocytochemical localization of μ-opioid receptor in the rat caudateputamen. Neurosci. Lett. 184, 149-152.
25. Kar, S., Rees, R.G., Quirion, R., 1994. Altered calcitonin gene-related peptide, substance P and enkephalin immunoreactivities and receptor binding sites in the dorsal spinal cord of the polyarthritic rat. Eur. J. Neurosci. 6, 345-354.
26. Kayser, V., Guilbaud, G., 1983. The analgesic effects of morphine, but not those of the enkephalinase inhibitor thiorphan, are enhanced in arthritic rats. Brain Res. 267, 131-138.
27. Levine, J.D., Taiwo, Y.O., 1989. Involvement of the μ-opiate receptor in peripheral analgesia. Neuroscience 32, 571-575.
28. Mansour, A., Fox, C.A., Thompson, R.C., Akil, H., Watson, S.J., 1994. μ-opioid receptor mRNA expression in the rat CNS: comparison to μ-receptor binding. Brain Res. 643, 245-265.
29. Millan, M.J., Millan, M.H., Czlonkowski, C., Höllt, V., Pilcher, C.W., Herz, A., Colpaert, F.C., 1986. A model of chronic pain in the rat: response of multiple opioid systems to adjuvant-induced arthritis. J. Neurosci. 6, 899-906.
30. Molander, C., Xu, Q., Grant, G., 1984. The cytoarchitectonic organization of the spinal cord in the rat. I. The lower thoracic and lumbosacral cord. J. Comp. Neurol. 230, 133-141.
31. Nakagawa, T., Minami, M., Satoh, M., 2001. Up-regulation of RGS4 mRNA by opioid receptor agonists in PC12 cells expressing cloned μ- and κ-opioid receptors. Eur. J. Pharmacol. 433, 29-36.
32. Pan, Y.X., Xu, J., Bolan, E., Abbadie, C., Chang, A., Zuckerman, A., Rossi, G., Pasternak, G.W., 1999. Identification and characterization of three new alternatively spliced μ-opioid receptor isoforms. Mol. Pharmacol. 56, 396-403.
33. Pircio, A.W., Fedele, C.T., Bierwagen, M.E., 1975. A new method for the evaluation of analgesic activity using adjuvant-induced arthritis in the rat. Eur. J. Pharmacol. 31, 207-215.
34. Pohl, M., Ballet, S., Collin, E., Mauborgne, A., Bourgoin, S., Benoliel, J.J., Hamon, M., Cesselin, F., 1997. Enkephalinergic and dynorphinergic neurons in the spinal cord and dorsal root ganglia of the polyarthritic rat. In vivo release and cDNA hybridization studies. Brain Res. 749, 18-28.
35. Pol, O., Alameda, F., Puig, M.M., 2001. Inflammation enhances μ-opioid receptor transcription and expression in mice intestine. Mol. Pharmacol. 60, 894-899.
36. Rodriguez-Puertas, R., Gonzales-Maeso, J., Meana, J.J., Pazos, A., 2000. Autoradiography of receptor-activated G-proteins in post mortem human brain. Neuroscience 96, 169-180.
37. 35S]thio]-triphosphate binding. Proc. Natl. Acad. Sci. USA 92, 7242-7246.
38. Stanfa, L.C., Sullivan, A.F., Dickenson, A.H., 1992. Alterations in neuronal excitability and the potency of spinal μ, δ and κ opioids after carrageenan-induced inflammation. Pain 50, 345-354.
39. Stein, C., Cabot, P.J., Schäfer, M., 1999. Peripheral opioid analgesia: mechanisms and clinical implications. In: Stein, C. (Ed.), Opioid in Pain Control. Basic and Clinical Aspects. Cambridge University Press, Cambridge, pp. 96-108.
40. Stein, C., Gramsch, C., Herz, A., 1990. Intrinsic mechanisms of antinociception in inflammation: local opioid receptors and β-endorphin. J. Neurosci. 10, 1292-1298.
41. Stein, C., Millan, M.J., Shippenberg, T.S., Peter, K., Herz, A., 1989. Peripheral opioid receptors mediating antinociception in inflammation. Evidence for involvement of μ, δ and κ receptors. J. Pharmacol. Exp. Ther. 248, 1269-1275.
42. Thompson, R.C., Mansour, A., Akil, H., Watson, S.J., 1993. Cloning and pharmacological characterization of rat μ opioid receptor. Neuron 11, 903-913.
43. Willis, W.D., Coggeshall, R.E., 1991. In: Sensory Mechanisms of the Spinal Cord. Plenum, New York, p. 590.
44. Zarbin, M.A., Wamsley, J.K., Kuhar, M.J., 1990. Anterograde transport of opioid receptors in rat vagus nerves and dorsal roots of spinal nerves: pharmacology and sensitivity to sodium and guanine nucleotides. Exp. Brain Res. 81, 267-278.
45. Zhang, Q., Schäfer, M., Elde, R., Stein, C., 1998a. Effects of neurotoxins and hindpaw inflammation on opioid receptor immunoreactivities in dorsal root ganglia. Neuroscience 85, 281-291.
46. Zhang, X., Bao, L., Shi, T.J., Ju, G., Elde, R., Hökfelt, T., 1998b. Down-regulation of μ-opioid receptors in rat and monkey dorsal root ganglion neurons and spinal cord after peripheral axotomy. Neuroscience 82, 223-240.