The pro-nociceptive effects of remifentanil or surgical injury in mice are associated with a decrease in delta-opioid receptor mRNA levels: Prevention of the nociceptive response by on-site delivery of enkephalins

Pain

Volumn 141, Issue 1-2, 2009, Pages 88-96

  Cabañero, David ^a   Célérier, Evelyne ^a   García Nogales, Paula ^a   Mata, Marina ^b   Roques, Bernard P ^c   Maldonado, Rafael ^d   Puig, Margarita M ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c CNRS   (France)

^d UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

DOR and MOR expression; Enkephalinase inhibition by RB101; HSV proenkephalin vector; Opioid induced pronociception; Postoperative pain

Indexed keywords

DELTA OPIATE RECEPTOR; HERPESVIRUS VECTOR; MESSENGER RNA; MU OPIATE RECEPTOR; N [3 [(2 AMINO 4 METHYLTHIO)BUTYLDITHIO] 2 BENZYLPROPIONYL]PHENYLALANINE BENZYL ESTER; PROENKEPHALIN; REMIFENTANIL;

ALLODYNIA; ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; HERPES SIMPLEX VIRUS; HYPERALGESIA; INCISION; MOUSE; NOCICEPTION; NONHUMAN; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; SENSITIZATION; SPINAL CORD; SPINAL GANGLION; SURGICAL INJURY; WESTERN BLOTTING;

ANALGESICS; ANIMALS; DISEASE MODELS, ANIMAL; DISULFIDES; DOWN-REGULATION; ENKEPHALINS; GANGLIA, SPINAL; MALE; METHYL ETHERS; MICE; PAIN MEASUREMENT; PAIN THRESHOLD; PAIN, POSTOPERATIVE; PHENYLALANINE; PIPERIDINES; PROTEIN PRECURSORS; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; RNA, MESSENGER; SPINAL CORD; TIME FACTORS;

EID: 58149260263     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2008.10.011     Document Type: Article

References (41)

1. Angst M.S., and Clark J.D. Opioid-induced hyperalgesia: a qualitative systematic review. Anesthesiology 104 (2006) 570-587
2. Antunes Bras J., Becker C., Bourgoin S., Lombard M., Cesselin F., Hamon M., et al. Met-enkephalin is preferentially transported into the peripheral processes of primary afferent fibres in both control and HSV1-driven proenkephalin A overexpressing rats. Neuroscience 103 (2001) 1073-1083
3. Antunes Bras J.M., Epstein A.L., Bourgoin S., Hamon M., Cesselin F., and Pohl M. Herpes simplex virus 1-mediated transfer of preproenkephalin A in rat dorsal root ganglia. J Neurochem 70 (1998) 1299-1303
4. Bookout A.L., and Mangelsdorf D.J. Quantitative real-time PCR protocol for analysis of nuclear receptor signaling pathways. Nucl Recept Signal 1 (2003) e012
5. Brack A., Rittner H.L., Machelska H., Shaqura M., Mousa S.A., Labuz D., et al. Endogenous peripheral antinociception in early inflammation is not limited by the number of opioid-containing leukocytes but by opioid receptor expression. Pain 108 (2004) 67-75
6. Celerier E., Gonzalez J.R., Maldonado R., Cabanero D., and Puig M.M. Opioid-induced hyperalgesia in a murine model of postoperative pain: role of nitric oxide generated from the inducible nitric oxide synthase. Anesthesiology 104 (2006) 546-555
7. Chaplan S.R., Bach F.W., Pogrel J.W., Chung J.M., and Yaksh T.L. Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods 53 (1994) 55-63
8. Chu L.F., Clark D.J., and Angst M.S. Opioid tolerance and hyperalgesia in chronic pain patients after one month of oral morphine therapy: a preliminary prospective study. J Pain 7 (2006) 43-48
9. Contet C., Gaveriaux-Ruff C., Matifas A., Caradec C., Champy M.F., and Kieffer B.L. Dissociation of analgesic and hormonal responses to forced swim stress using opioid receptor knockout mice. Neuropsychopharmacology 31 (2006) 1733-1744
10. Dauge V., Corringer P.J., and Roques B.P. CCKA, but not CCKB, agonists suppress the hyperlocomotion induced by endogenous enkephalins, protected from enzymatic degradation by systemic RB 101. Pharmacol Biochem Behav 50 (1995) 133-139
11. Fournie-Zaluski M.C., Coric P., Turcaud S., Lucas E., Noble F., Maldonado R., et al. ''Mixed inhibitor-prodrug" as a new approach toward systemically active inhibitors of enkephalin-degrading enzymes. J Med Chem 35 (1992) 2473-2481
12. Gavériaux-Ruff C., Karchewski L.A., Hever X., Matifas A., and Kieffer B.L. Inflammatory pain is enhanced in delta opioid receptor-knockout mice. Eur J Neurosci 27 (2008) 2558-2567
13. Gomes I., Gupta A., Filipovska J., Szeto H.H., Pintar J.E., and Devi L.A. A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia. Proc Natl Acad Sci USA 101 (2004) 5135-5139
14. Goss J.R., Harley C.F., Mata M., O'Malley M.E., Goins W.F., Hu X., et al. Herpes vector-mediated expression of proenkephalin reduces bone cancer pain. Ann Neurol 52 (2002) 662-665
15. Goss J.R., Mata M., Goins W.F., Wu H.H., Glorioso J.C., and Fink D.J. Antinociceptive effect of a genomic herpes simplex virus-based vector expressing human proenkephalin in rat dorsal root ganglion. Gene Ther 8 (2001) 551-556
16. Hao J.X., Yu W., and Xu X.J. Evidence that spinal endogenous opioidergic systems control the expression of chronic pain-related behaviors in spinally injured rats. Exp Brain Res 118 (1998) 259-268
17. Hao S., Mata M., Goins W., Glorioso J.C., and Fink D.J. Transgene-mediated enkephalin release enhances the effect of morphine and evades tolerance to produce a sustained antiallodynic effect in neuropathic pain. Pain 102 (2003) 135-142
18. Hargreaves K., Dubner R., Brown F., Flores C., and Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32 (1988) 77-88
19. Henriksen G., and Willoch F. Imaging of opioid receptors in the central nervous system. Brain 131 (2008) 1171-1196
20. Igwe O.J., Kim D.C., Seybold V.S., and Larson A.A. Specific binding of substance P aminoterminal heptapeptide [SP(1-7)] to mouse brain and spinal cord membranes. J Neurosci 10 (1990) 3653-3663
21. Ji R.R., Zhang Q., Law P.Y., Low H.H., Elde R., and Hokfelt T. Expression of mu-, delta-, and kappa-opioid receptor-like immunoreactivities in rat dorsal root ganglia after carrageenan-induced inflammation. J Neurosci 15 (1995) 8156-8166
22. Joly V., Richebe P., Guignard B., Fletcher D., Maurette P., Sessler D.I., et al. Remifentanil-induced postoperative hyperalgesia and its prevention with small-dose ketamine. Anesthesiology 103 (2005) 147-155
23. Kabli N., and Cahill C.M. Anti-allodynic effects of peripheral delta opioid receptors in neuropathic pain. Pain 127 (2007) 84-93
24. Kondo I., Marvizon J.C., Song B., Salgado F., Codeluppi S., Hua X.Y., et al. Inhibition by spinal mu- and delta-opioid agonists of afferent-evoked substance P release. J Neurosci 25 (2005) 3651-3660
25. Lee J.Y., Fink D.J., and Mata M. Vector-mediated gene transfer to express inhibitory neurotransmitters in dorsal root ganglion reduces pain in a rodent model of lumbar radiculopathy. Spine 31 (2006) 1555-1558
26. Li X., Angst M.S., and Clark J.D. A murine model of opioid-induced hyperalgesia. Brain Res Mol Brain Res 86 (2001) 56-62
27. Lisi T.L., and Sluka K.A. A new electrochemical HPLC method for analysis of enkephalins and endomorphins. J Neurosci Methods 150 (2006) 74-79
28. Liu J., Wolfe D., Hao S., Huang S., Glorioso J.C., Mata M., et al. Peripherally delivered glutamic acid decarboxylase gene therapy for spinal cord injury pain. Mol Ther 10 (2004) 57-66
29. Livak KJ. Comparative Ct method. ABI Prism 7700 Sequence Detection System. PE Applied Biosystems 1997;User Bulletin no. 2.
30. Luo M.C., Zhang D.Q., Ma S.W., Huang Y.Y., Shuster S.J., Porreca F., et al. An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons. Mol Pain 1 (2005) 29
31. Nadal X., Banos J.E., Kieffer B.L., and Maldonado R. Neuropathic pain is enhanced in delta-opioid receptor knockout mice. Eur J Neurosci 23 (2006) 830-834
32. Nieto M.M., Guen S.L., Kieffer B.L., Roques B.P., and Noble F. Physiological control of emotion-related behaviors by endogenous enkephalins involves essentially the delta opioid receptors. Neuroscience 135 (2005) 305-313
33. Nieto M.M., Wilson J., Walker J., Benavides J., Fournie-Zaluski M.C., Roques B.P., et al. Facilitation of enkephalins catabolism inhibitor-induced antinociception by drugs classically used in pain management. Neuropharmacology 41 (2001) 496-506
34. Ossipov M.H., Lai J., King T., Vanderah T.W., and Porreca F. Underlying mechanisms of pronociceptive consequences of prolonged morphine exposure. Biopolymers 80 (2005) 319-324
35. Pinheiro J.C., and Bates D.M. Mixed-effects models in S and S-plus, statistics and computing series (2000), Springer-Verlag, New York
36. Snook L.A., Milligan G., Kieffer B.L., and Massotte D. Mu-delta opioid receptor functional interaction: insight using receptor-G protein fusions. J Pharmacol Exp Ther 318 (2006) 683-690
37. Stone L.S., Vulchanova L., Riedl M.S., Williams F.G., Wilcox G.L., and Elde R. Effects of peripheral nerve injury on delta opioid receptor (DOR) immunoreactivity in the rat spinal cord. Neurosci Lett 361 (2004) 208-211
38. Vera-Portocarrero L.P., Zhang E.T., King T., Ossipov M.H., Vanderah T.W., Lai J., et al. Spinal NK-1 receptor expressing neurons mediate opioid-induced hyperalgesia and antinociceptive tolerance via activation of descending pathways. Pain (2006)
39. Wang H., and Wessendorf M.W. Equal proportions of small and large DRG neurons express opioid receptor mRNAs. J Comp Neurol 429 (2001) 590-600
40. Yamada H., Shimoyama N., Sora I., Uhl G.R., Fukuda Y., Moriya H., et al. Morphine can produce analgesia via spinal kappa opioid receptors in the absence of mu opioid receptors. Brain Res 1083 (2006) 61-69
41. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16 (1983) 109-110