Prophylaxis and treatment of the side-effects of neuraxial morphine analgesia following cesarean delivery

Current Opinion in Anaesthesiology

Volumn 26, Issue 3, 2013, Pages 288-295

  Dominguez, Jennifer E ^a   Habib, Ashraf S ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cesarean delivery; Epidural morphine; Nausea; Pruritus; Spinal morphine; Vomiting

Indexed keywords

ALIZAPRIDE; ANTIEMETIC AGENT; ANTIHISTAMINIC AGENT; ATROPINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; DEXAMETHASONE; DIMENHYDRINATE; DIPHENHYDRAMINE; DROPERIDOL; GRANISETRON; METOCLOPRAMIDE; MORPHINE; MU OPIATE RECEPTOR; NALBUPHINE; NALOXONE; ONDANSETRON; PENTAZOCINE; PLACEBO; PROMETHAZINE; SCOPOLAMINE; SEROTONIN 3 ANTAGONIST; NARCOTIC ANALGESIC AGENT;

ACUPRESSURE; ANALGESIA; ANTICHOLINERGIC EFFECT; CESAREAN SECTION; DISEASE SEVERITY; DOSE RESPONSE; DRUG EFFICACY; GENETIC POLYMORPHISM; HUMAN; POSTOPERATIVE NAUSEA AND VOMITING; PRIORITY JOURNAL; PRURITUS; REVIEW; ADULT; CHEMICALLY INDUCED; EPIDURAL ANESTHESIA; FEMALE; NEWBORN; OBSTETRIC ANALGESIA; PAIN, POSTOPERATIVE; PREGNANCY;

ADULT; ANALGESIA, EPIDURAL; ANALGESIA, OBSTETRICAL; ANALGESICS, OPIOID; ANTIEMETICS; CESAREAN SECTION; FEMALE; HUMANS; INFANT, NEWBORN; MORPHINE; PAIN, POSTOPERATIVE; POSTOPERATIVE NAUSEA AND VOMITING; PREGNANCY; PRURITUS;

EID: 84877790352     PISSN: 09527907     EISSN: 14736500     Source Type: Journal    
DOI: 10.1097/ACO.0b013e328360b086     Document Type: Review

References (46)

1. Abouleish E, Rawal N, Rashad MN. The addition of 0.2mg subarachnoid morphine to hyperbaric bupivacaine for cesarean delivery: A prospective study of 856 cases. Reg Anesth 1991; 16:137-140
2. Dahl JB, Jeppesen IS, Jorgensen H, et al. Intraoperative and postoperative analgesic efficacy and adverse effects of intrathecal opioids in patients undergoing cesarean section with spinal anesthesia: A qualitative and quantitative systematic review of randomized controlled trials. Anesthesiology 1999; 91:1919-1927
3. Carvalho B, Cohen SE, Lipman SS, et al. Patient preferences for anesthesia outcomes associated with cesarean delivery. Anesth Analg 2005; 101:1182-1187
4. Palmer CM, Emerson S, Volgoropolous D, Alves D. Dose-response relationship of intrathecal morphine for postcesarean analgesia. Anesthesiology 1999; 90:437-444
5. Palmer CM, Nogami WM, Van Maren G, Alves DM. Postcesarean epidural morphine: A dose-response study. Anesth Analg 2000; 90:887-891
6. Girgin NK, Gurbet A, Turker G, et al. Intrathecal morphine in anesthesia for cesarean delivery: Dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine. J Clin Anesth 2008; 20:180-185
7. Mikuni I, Hirai H, Toyama Y, et al. Efficacy of intrathecal morphine with epidural ropivacaine infusion for postcesarean analgesia. J Clin Anesth 2010; 22:268-273
8. Wong JY, Carvalho B, Riley ET. Intrathecal morphine 100 and 200 mg for postcesarean delivery analgesia: A trade-off between analgesic efficacy and side effects. Int J Obstet Anesth 2013; 22:36-41
9. Balki M, Carvalho JC. Intraoperative nausea and vomiting during cesarean section under regional anesthesia. Int J Obstet Anesth 2005; 14:230-241
10. Griffiths JD, Gyte GM, Paranjothy S, et al. Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section. Cochrane Database Syst Rev 2012; 9:CD007579
11. Mishriky BM, Habib AS. Metoclopramide for nausea and vomiting prophylaxis during and after caesarean delivery: A systematic review and meta-Analysis. Br J Anaesth 2012; 108:374-383
12. Mishriky BM, Habib AS. Impact of data by Fujii and colleagues on the metaanalysis of metoclopramide for antiemetic prophylaxis in women undergoing caesarean delivery under neuraxial anaesthesia. Br J Anaesth 2012; 109:826
13. George RB, Allen TK, Habib AS. Serotonin receptor antagonists for the prevention and treatment of pruritus, nausea, and vomiting in women undergoing cesarean delivery with intrathecal morphine: A systematic review and meta-Analysis. Anesth Analg 2009; 109:174-182
14. Allen TK, Jones CA, Habib AS. Dexamethasone for the prophylaxis of postoperative nausea and vomiting associated with neuraxial morphine administration: A systematic review and meta-Analysis. Anesth Analg 2012; 114:813-822
15. Duman A, Apiliogullari S, Gok F, et al. A randomized comparison of dimenhydrinate, metoclopramide, and placebo for the prevention of nausea and vomiting following intrathecal fentanyl and morphine in cesarean delivery. Nobel Medicus 2010; 6:13-19
16. Habib AS, George RB, McKeen DM, et al. Antiemetics added to phenylephrine infusion during cesarean delivery: A randomized controlled trial. Obstet Gynecol 2013; 121:615-623
17. Harnett MJ, O'Rourke N, Walsh M, et al. Transdermal scopolamine for prevention of intrathecal morphine-induced nausea and vomiting after cesarean delivery. Anesth Analg 2007; 105:764-769
18. Henzi I, Walder B, Tramer MR. Dexamethasone for the prevention of postoperative nausea and vomiting: A quantitative systematic review. Anesth Analg 2000; 90:186-194
19. Waldron NH, Jones CA, Gan TJ, et al. Impact of perioperative dexamethasone on postoperative analgesia and side-effects: Systematic review and metaanalysis. Br J Anaesth 2013; 110:191-200
20. Cardoso MM, Leite AO, Santos EA, et al. Effect of dexamethasone on prevention of postoperative nausea, vomiting and pain after caesarean section: A randomised, placebo-controlled, double-blind trial. Eur J Anaesthesiol 2013; 30:102-105
21. Baciarello M, Cornini A, Zasa M, et al. Intrathecal atropine to prevent postoperative nausea and vomiting after cesarean section: A randomized, controlled trial. Minerva Anestesiol 2011; 77:781-788
22. Apfel CC, Korttila K, Abdalla M, et al. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med 2004; 350:2441-2451
23. Abdel-Aleem M, Osman A, Morsy K. Effect of coadministration of dexamethasone with intrathecal morphine on postoperative outcomes after cesarean delivery. Int J Gynaecol Obstet 2012; 116:158-161
24. Allen TK, Habib AS. P6 stimulation for the prevention of nausea and vomiting associated with cesarean delivery under neuraxial anesthesia: A systematic review of randomized controlled trials. Anesth Analg 2008; 107:1308-1312
25. Phillips TW Jr, Broussard DM, Sumrall WD 3rd, Hart SR. Intraoperative oxygen administration does not reduce the incidence or severity of nausea or vomiting associated with neuraxial anesthesia for cesarean delivery. Anesth Analg 2007; 105:1113-1117
26. Pecora FS, Malbouisson LM, Torres ML. Supplemental oxygen and the incidence of perioperative nausea and vomiting in cesarean sections under subarachnoid block. Rev Bras Anestesiol 2009; 59:558-569
27. Gan TJ, Meyer TA, Apfel CC, et al. Society for Ambulatory Anesthesia guidelines for the management of postoperative nausea and vomiting. Anesth Analg 2007; 105:1615-1628
28. Habib AS, Reuveni J, Taguchi A, et al. A comparison of ondansetron with promethazine for treating postoperative nausea and vomiting in patients who received prophylaxis with ondansetron: A retrospective database analysis. Anesth Analg 2007; 104:548-551
29. Sposito JA, Habib AS. Low-dose naloxone infusion for the treatment of intractable nausea and vomiting after intrathecal morphine in a parturient. Int J Obstet Anesth 2010; 19:119-121
30. Szarvas S, Harmon D, Murphy D. Neuraxial opioid-induced pruritus: A review. J Clin Anesth 2003; 15:234-239
31. Tsai FF, Fan SZ, Yang YM, et al. Human opioid mu-receptor A118G polymorphism may protect against central pruritus by epidural morphine for postcesarean analgesia. Acta Anaesthesiol Scand 2010; 54:1265-1269
32. Wong CA, McCarthy RJ, Blouin J, Landau R. Observational study of the effect of mu-opioid receptor genetic polymorphism on intrathecal opioid labor analgesia and postcesarean delivery analgesia. Int J Obstet Anesth 2010; 19:246-253
33. Kjellberg F, Tramer MR. Pharmacological control of opioid-induced pruritus: A quantitative systematic review of randomized trials. Eur J Anaesthesiol 2001; 18:346-357
34. Tan T, Ojo R, Immani S, et al. Reduction of severity of pruritus after elective caesarean section under spinal anaesthesia with subarachnoid morphine: A randomised comparison of prophylactic granisetron and ondansetron. Int J Obstet Anesth 2010; 19:56-60
35. Siddik-Sayyid SM, Aouad MT, Taha SK, et al. Does ondansetron or granisetron prevent subarachnoid morphine-induced pruritus after cesarean delivery? Anesth Analg 2007; 104:421-424
36. Han DW, Hong SW, Kwon JY, et al. Epidural ondansetron is more effective to prevent postoperative pruritus and nausea than intravenous ondansetron in elective cesarean delivery. Acta Obstet Gynecol Scand 2007; 86:683-687
37. Liao CC, Chang CS, Tseng CH, et al. Efficacy of intramuscular nalbuphine versus diphenhydramine for the prevention of epidural morphine-induced pruritus after cesarean delivery. Chang Gung Med J 2011; 34:172-178
38. Pongraweewan O, Santawata U, Weerasarn L, et al. Epidural nalbuphine for post cesarean epidural morphine induced pruritus. J Med Assoc Thai 2009; 92:782-786
39. Wu Z, Kong M, Wang N, et al. Intravenous butorphanol administration reduces intrathecal morphine-induced pruritus after cesarean delivery: A randomized, double-blind, placebo-controlled study. J Anesth 2012; 26:752-757
40. Lockington PF, Fa'aea P. Subcutaneous naloxone for the prevention of intrathecal morphine induced pruritus in elective caesarean delivery. Anaesthesia 2007; 62:672-676
41. Jeon Y, Hwang J, Kang J, et al. Effects of epidural naloxone on pruritus induced by epidural morphine: A randomized controlled trial. Int J Obstet Anesth 2005; 14:22-25
42. Horta ML, Morejon LC, da Cruz AW, et al. Study of the prophylactic effect of droperidol, alizapride, propofol and promethazine on spinal morphine-induced pruritus. Br J Anaesth 2006; 96:796-800
43. Charuluxananan S, Somboonviboon W, Kyokong O, Nimcharoendee K. Ondansetron for treatment of intrathecal morphine-induced pruritus after cesarean delivery. Reg Anesth Pain Med 2000; 25:535-539
44. Borgeat A, Stirnemann HR. Ondansetron is effective to treat spinal or epidural morphine-induced pruritus. Anesthesiology 1999; 90:432-436
45. Tamdee D, Charuluxananan S, Punjasawadwong Y, et al. A randomized controlled trial of pentazocine versus ondansetron for the treatment of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery. Anesth Analg 2009; 109:1606-1611
46. Siddik-Sayyid SM, Yazbeck-KaramVG, Zahreddine BW, et al. Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery. Acta Anaesthesiol Scand 2010; 54:764-769