Map4k4 suppresses Srebp-1 and adipocyte lipogenesis independent of JNK signaling

Journal of Lipid Research

Volumn 54, Issue 10, 2013, Pages 2697-2707

  Danai, Laura V ^a   Guilherme, Adilson ^a   Guntur, Kalyani V ^a,b   Straubhaar, Juerg ^a   Nicoloro, Sarah M ^a   Czech, Michael P ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b Berg Biosystems   (United States)

Author keywords

AMP protein kinase; C Jun NH 2 terminal kinase; Insulin; Lipid synthesis; Mechanistic target of rapamycin; Mitogen activated protein kinase kinase kinase kinase 4; Sterol regulated element binding protein 1

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; JANUS KINASE 1; JANUS KINASE 2; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 4; SERINE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; GENOME ANALYSIS; LIPOGENESIS; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

AMP-PROTEIN KINASE; C-JUN NH2-TERMINAL KINASE; INSULIN; LIPID SYNTHESIS; MECHANISTIC TARGET OF RAPAMYCIN; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 4; STEROL-REGULATED ELEMENT BINDING PROTEIN-1;

3T3-L1 CELLS; ADIPOCYTES; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ENZYME ACTIVATION; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; LIPOGENESIS; MAP KINASE SIGNALING SYSTEM; MICE; OBESITY; PROTEIN-SERINE-THREONINE KINASES; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TOR SERINE-THREONINE KINASES; TRANSCRIPTIONAL ACTIVATION; TRIGLYCERIDES;

EID: 84884149694     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M038802     Document Type: Article

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