Preventing phosphorylation of sterol regulatory element-binding protein 1a by MAP-kinases protects mice from fatty liver and visceral obesity

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Kotzka, Jorg ^a   Knebel, Birgit ^a   Haas, Jutta ^b   Kremer, Lorena ^a   Jacob, Sylvia ^a   Hartwig, Sonja ^a   Nitzgen, Ulrike ^a   Muller Wieland, Dirk ^b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SERINE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1A; STRESS ACTIVATED PROTEIN KINASE; THREONINE; DNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ABDOMINAL OBESITY; ADIPOSE TISSUE; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOLOGY; DYSLIPIDEMIA; ENHANCER REGION; ENZYME ACTIVITY; FATTY LIVER; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHENOTYPE; PROMOTER REGION; PROTECTION; PROTEIN ANALYSIS; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; BINDING SITE; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; SIGNAL TRANSDUCTION;

MUS; MUS MUSCULUS;

ANIMALS; BINDING SITES; DNA; FATTY LIVER; HEP G2 CELLS; HUMANS; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MICE; MICE, TRANSGENIC; OBESITY, ABDOMINAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOTYPE; PHOSPHORYLATION; PROTEIN BINDING; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84857548618     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032609     Document Type: Article

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