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Volumn 16, Issue 6, 1997, Pages 1279-1290

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

Author keywords

MEKK1; Nck interacting kinase; Ste20 related kinase; Stress activated protein kinase

Indexed keywords

CELL SURFACE RECEPTOR; PHOSPHOTRANSFERASE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE;

EID: 0030907935     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.6.1279     Document Type: Article
Times cited : (223)

References (56)
  • 1
    • 0029680639 scopus 로고    scopus 로고
    • Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in immunodeficiency disorder Wiskott-Aldrich syndrome
    • Aspenstrom, P., Lindberg, U. and Hall, A. (1996) Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in immunodeficiency disorder Wiskott-Aldrich syndrome. Curr. Biol., 6, 70-75.
    • (1996) Curr. Biol. , vol.6 , pp. 70-75
    • Aspenstrom, P.1    Lindberg, U.2    Hall, A.3
  • 2
    • 0028875683 scopus 로고
    • Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation
    • Bagrodia, S., Derijard, B., Davis, R.J. and Cerione, R.A. (1995) Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation. J. Biol. Chem., 270, 27995-27998.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27995-27998
    • Bagrodia, S.1    Derijard, B.2    Davis, R.J.3    Cerione, R.A.4
  • 3
    • 0029913457 scopus 로고    scopus 로고
    • Molecular cloning of Mitogen-activated protein/ERK Kinase Kinases (MEKK) 2 and 3
    • Blank, J., Bervins, P., Elliott, E.M., Sather, S. and Johnson, G.L. (1996) Molecular cloning of Mitogen-activated protein/ERK Kinase Kinases (MEKK) 2 and 3. J. Biol. Chem., 271, 5361-5368.
    • (1996) J. Biol. Chem. , vol.271 , pp. 5361-5368
    • Blank, J.1    Bervins, P.2    Elliott, E.M.3    Sather, S.4    Johnson, G.L.5
  • 4
    • 0023392945 scopus 로고
    • High efficiency transformation of mammalian cells by plasmid DNA
    • Chen, C. and Okiyama, H. (1987) High efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7, 2745-2752.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2745-2752
    • Chen, C.1    Okiyama, H.2
  • 5
    • 0027983908 scopus 로고
    • Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating of S. cerevisiae
    • Choi, K.Y., Scatterberg, B., Lyons, D.M. and Elion, E.A. (1994) Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating of S. cerevisiae. Cell, 78, 499-512.
    • (1994) Cell , vol.78 , pp. 499-512
    • Choi, K.Y.1    Scatterberg, B.2    Lyons, D.M.3    Elion, E.A.4
  • 6
    • 0028904384 scopus 로고
    • A novel ligand for SH3 domains
    • Chou, M.M. and Hanafusa, H. (1995) A novel ligand for SH3 domains J. Biol. Chem., 270, 7359-7364.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7359-7364
    • Chou, M.M.1    Hanafusa, H.2
  • 7
    • 0026453352 scopus 로고
    • The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels
    • Chou, M.M., Fajardo, E. and Hanafusa, H. (1992) The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels. Mol. Cell. Biol., 12, 5834-5842.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 5834-5842
    • Chou, M.M.1    Fajardo, E.2    Hanafusa, H.3
  • 8
    • 0029043582 scopus 로고
    • How MAP kinases are regulated
    • Cobb, M.H. and Goldsmith, E.J. (1995) How MAP kinases are regulated. J. Biol. Chem., 270, 14843-14846.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14843-14846
    • Cobb, M.H.1    Goldsmith, E.J.2
  • 9
    • 0028895654 scopus 로고
    • Modular binding domains in signal transduction proteins
    • Cohen, G.B., Ren, R. and Baltimore, D. (1995) Modular binding domains in signal transduction proteins. Cell, 80, 237-248.
    • (1995) Cell , vol.80 , pp. 237-248
    • Cohen, G.B.1    Ren, R.2    Baltimore, D.3
  • 10
    • 0029101740 scopus 로고
    • Cloning and characterization of human protein kinase with homology to Ste20
    • Creasy, C.L. and Chernoff, J. (1995) Cloning and characterization of human protein kinase with homology to Ste20. J. Biol. Chem., 270, 21695-21700.
    • (1995) J. Biol. Chem. , vol.270 , pp. 21695-21700
    • Creasy, C.L.1    Chernoff, J.2
  • 11
    • 0028073283 scopus 로고
    • MAPKs: New JNK expands the group
    • Davis, R.J. (1994) MAPKs: new JNK expands the group. Trends Biochem. Sci., 19, 470-473.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 470-473
    • Davis, R.J.1
  • 12
    • 0028935974 scopus 로고
    • Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms
    • Derijard, B., Raingeaud, J., Barrett, T., Wu, I.-H., Han, J., Ulevitch, R.J. and Davis, R.J. (1995) Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms. Science, 267, 682-685.
    • (1995) Science , vol.267 , pp. 682-685
    • Derijard, B.1    Raingeaud, J.2    Barrett, T.3    Wu, I.-H.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 13
    • 0022340978 scopus 로고
    • Isolation of monoclonal antibodies specific for human c-myc protooncogene product
    • Evan, G.I., Lewis, G.K., Ramsay, G. and Bishop, J.M. (1985) Isolation of monoclonal antibodies specific for human c-myc protooncogene product. Mol. Cell. Biol., 5, 3610-3616.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 3610-3616
    • Evan, G.I.1    Lewis, G.K.2    Ramsay, G.3    Bishop, J.M.4
  • 14
    • 0028071624 scopus 로고
    • Mutation of Sps1-encoded protein kinase of Saccharomyces cerevisiae leads to defects in transcription and morphology during spore formation
    • Friesen, H., Lunz, R., Doyle, S. and Segall, J. (1994) Mutation of Sps1-encoded protein kinase of Saccharomyces cerevisiae leads to defects in transcription and morphology during spore formation. Genes Dev., 8, 2162-2175.
    • (1994) Genes Dev. , vol.8 , pp. 2162-2175
    • Friesen, H.1    Lunz, R.2    Doyle, S.3    Segall, J.4
  • 15
    • 0029830139 scopus 로고    scopus 로고
    • The adaptor protein Nek links receptor tyrosine kinases with the serine-threonine kinase Pak1
    • Galisteo, M.L., Chernoff, J., Su, Y.-C., Skolnik, E.Y. and Schlessinger, J. (1996) The adaptor protein Nek links receptor tyrosine kinases with the serine-threonine kinase Pak1. J. Biol. Chem., 271, 20997-21000
    • (1996) J. Biol. Chem. , vol.271 , pp. 20997-21000
    • Galisteo, M.L.1    Chernoff, J.2    Su, Y.-C.3    Skolnik, E.Y.4    Schlessinger, J.5
  • 16
    • 0029943447 scopus 로고    scopus 로고
    • Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein
    • Garrity, P.A., Rao, Y., Salecker, I., McGlade, J., Pawson, T. and Zipursky, L. (1996) Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein. Cell, 85, 639-650.
    • (1996) Cell , vol.85 , pp. 639-650
    • Garrity, P.A.1    Rao, Y.2    Salecker, I.3    McGlade, J.4    Pawson, T.5    Zipursky, L.6
  • 17
    • 0028905076 scopus 로고
    • Transcription factor ATF2 regulation by the JNK signal transduction pathway
    • Gupta, S., Campbell,D., Derijard, B. and Davis, R.J. (1995) Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science, 267, 389-393.
    • (1995) Science , vol.267 , pp. 389-393
    • Gupta, S.1    Campbell, D.2    Derijard, B.3    Davis, R.J.4
  • 18
    • 0001624285 scopus 로고
    • Guide to yeast genetics and molecular biology
    • Guthrie, C. and Fink, G.R. (1992) Guide to yeast genetics and molecular biology. Methods Enzvmol., 194, 12-18.
    • (1992) Methods Enzvmol. , vol.194 , pp. 12-18
    • Guthrie, C.1    Fink, G.R.2
  • 19
    • 0027936755 scopus 로고
    • A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
    • Han, J., Lee, J.-D., Bibbs, L. and Ulevitch, R.J. (1994) A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science. 265, 808-811.
    • (1994) Science , vol.265 , pp. 808-811
    • Han, J.1    Lee, J.-D.2    Bibbs, L.3    Ulevitch, R.J.4
  • 20
    • 0030044182 scopus 로고    scopus 로고
    • Characterization of the structure and function of a novel MAP kinase kinase (MKK6)
    • Han, J., Lee, J.-D., Jiang, Y., Li, Z., Feng, L. and Ulevitch, R.J. (1996) Characterization of the structure and function of a novel MAP kinase kinase (MKK6). J. Biol. Chem., 271, 1886-1891.
    • (1996) J. Biol. Chem. , vol.271 , pp. 1886-1891
    • Han, J.1    Lee, J.-D.2    Jiang, Y.3    Li, Z.4    Feng, L.5    Ulevitch, R.J.6
  • 21
    • 0029020282 scopus 로고
    • The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification
    • Hanks, S.K. and Hunter, T. (1995) The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J., 9, 576-596.
    • (1995) FASEB J. , vol.9 , pp. 576-596
    • Hanks, S.K.1    Hunter, T.2
  • 22
    • 0028985079 scopus 로고
    • MAP kinase pathways in yeast: For mating and more
    • Herskowitz, I. (1995) MAP kinase pathways in yeast: for mating and more. Cell, 80, 187-197.
    • (1995) Cell , vol.80 , pp. 187-197
    • Herskowitz, I.1
  • 23
    • 0028817657 scopus 로고
    • Binding of NCK to SOS and activation of ras-dependent gene expression
    • Hu, Q., Milfay, D. and Williams, L.T. (1995) Binding of NCK to SOS and activation of ras-dependent gene expression. Mol. Cell. Biol., 15. 1169-1174.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1169-1174
    • Hu, Q.1    Milfay, D.2    Williams, L.T.3
  • 24
    • 0029763450 scopus 로고    scopus 로고
    • Human HPK1, a novel hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade
    • Hu, M.C.-T., Qiu, W.R., Wang, X., Meyer, C.F. and Tan, T.-H. (1996) Human HPK1, a novel hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade. Genes Dev., 10, 2251-2264.
    • (1996) Genes Dev. , vol.10 , pp. 2251-2264
    • Hu, M.C.-T.1    Qiu, W.R.2    Wang, X.3    Meyer, C.F.4    Tan, T.-H.5
  • 25
    • 13344278677 scopus 로고    scopus 로고
    • Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo
    • Isakoff, S.J., Yu, Y., Su, Y.-C., Blaikie, P., Yajnik, V., Rose, E., Weidner, K.M., Sachs, M., Margolis, B. and Skolnik, E.Y. (1996) Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo. J. Biol. Chem., 271, 3959-3962.
    • (1996) J. Biol. Chem. , vol.271 , pp. 3959-3962
    • Isakoff, S.J.1    Yu, Y.2    Su, Y.-C.3    Blaikie, P.4    Yajnik, V.5    Rose, E.6    Weidner, K.M.7    Sachs, M.8    Margolis, B.9    Skolnik, E.Y.10
  • 26
    • 0028609209 scopus 로고
    • JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation
    • Kallunki, T., Su, B., Tsigelny, I., Sluss, H.K., Derijard, B., Moore, G., Davis, R. and Karin, M. (1994) JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation. Genes Dev., 8, 2886-3007.
    • (1994) Genes Dev. , vol.8 , pp. 2886-3007
    • Kallunki, T.1    Su, B.2    Tsigelny, I.3    Sluss, H.K.4    Derijard, B.5    Moore, G.6    Davis, R.7    Karin, M.8
  • 27
    • 0028279796 scopus 로고
    • Differential expression of a novel protein kinase in human B lymphocytes
    • Katz, P., Whalen, G. and Kehrl, J.H. (1994) Differential expression of a novel protein kinase in human B lymphocytes. J. Biol. Chem., 269, 16802-16809.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16802-16809
    • Katz, P.1    Whalen, G.2    Kehrl, J.H.3
  • 28
    • 0024546509 scopus 로고
    • The scanning model for translation: An update
    • Kozak, M. (1989) The scanning model for translation: an update. J. Cell Biol., 108, 229-241.
    • (1989) J. Cell Biol. , vol.108 , pp. 229-241
    • Kozak, M.1
  • 29
    • 0028074621 scopus 로고
    • Ras-dependent growth factor regulation of MEK kinase in PC12 cells
    • Lange-Carter, C.A. and Johnson, G.L. (1994) Ras-dependent growth factor regulation of MEK kinase in PC12 cells. Science, 265, 1458-1461.
    • (1994) Science , vol.265 , pp. 1458-1461
    • Lange-Carter, C.A.1    Johnson, G.L.2
  • 31
    • 0025273452 scopus 로고
    • Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of Src homology units SH2 and SH3
    • Lehman, J.M., Riethmuller, G. and Johnson, J.P. (1990) Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of Src homology units SH2 and SH3. Nucleic Acids Res., 18, 1048.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 1048
    • Lehman, J.M.1    Riethmuller, G.2    Johnson, J.P.3
  • 32
    • 0026452004 scopus 로고
    • The SH2 and SH3 domain-containing Nek protein is oncogenic and a common target for phosphorylation by different surface receptors
    • Li, W., Skolnik, E.Y., Ullrich, A. and Schlessinger, J. (1992) The SH2 and SH3 domain-containing Nek protein is oncogenic and a common target for phosphorylation by different surface receptors. Mol. Cell. Biol., 12, 5824-5833.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 5824-5833
    • Li, W.1    Skolnik, E.Y.2    Ullrich, A.3    Schlessinger, J.4
  • 33
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by Cdc42 and Rac1
    • Manser, E., Leung, T., Salihuddin, H., Zhao, Z. and Lim, L. (1994) A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature, 367, 40-46.
    • (1994) Nature , vol.367 , pp. 40-46
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.4    Lim, L.5
  • 34
    • 0027991228 scopus 로고
    • Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module
    • Marcus, S., Poliverino, R., Barr, M. and Wigler, M. (1994) Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module. Proc. Natl Acad. Sci. USA, 91, 7762-7766.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 7762-7766
    • Marcus, S.1    Poliverino, R.2    Barr, M.3    Wigler, M.4
  • 35
    • 0029056399 scopus 로고
    • A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20
    • Martin, G.A., Bollag, G., McCormick, F. and Abo, A. (1995) A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20. EMBO J., 14, 1970-1978.
    • (1995) EMBO J. , vol.14 , pp. 1970-1978
    • Martin, G.A.1    Bollag, G.2    McCormick, F.3    Abo, A.4
  • 36
    • 0029281993 scopus 로고
    • Minding your p's and q's
    • Mayer, B.J. and Eck, M.J. (1995) Minding your p's and q's. Curr. Biol., 5, 364-367.
    • (1995) Curr. Biol. , vol.5 , pp. 364-367
    • Mayer, B.J.1    Eck, M.J.2
  • 38
    • 0026497434 scopus 로고
    • Phosphorylation of Nek in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP
    • Park, D. and Goo Rhee, S. (1992) Phosphorylation of Nek in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP. Mol. Cell. Biol., 12, 5816-5823.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 5816-5823
    • Park, D.1    Goo Rhee, S.2
  • 39
    • 0028859279 scopus 로고
    • Protein modules and signaling networks
    • Pawson, T. (1995) Protein modules and signaling networks. Nature, 373, 573-580.
    • (1995) Nature , vol.373 , pp. 573-580
    • Pawson, T.1
  • 41
    • 0029814060 scopus 로고    scopus 로고
    • Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway
    • Pombo, C.M., Bonventre, J.V., Molnar, A., Kyriakis, J. and Force, T. (1996) Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway. EMBO J., 15, 4537-4546.
    • (1996) EMBO J. , vol.15 , pp. 4537-4546
    • Pombo, C.M.1    Bonventre, J.V.2    Molnar, A.3    Kyriakis, J.4    Force, T.5
  • 42
    • 0028892253 scopus 로고
    • Phosphatidylinositol (3,4,5) P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins
    • Rameh, L., Chen, C.-S. and Cantley, L.C. (1995) Phosphatidylinositol (3,4,5) P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins. Cell, 83, 821-830.
    • (1995) Cell , vol.83 , pp. 821-830
    • Rameh, L.1    Chen, C.-S.2    Cantley, L.C.3
  • 43
    • 0027530380 scopus 로고
    • A dominant truncation allele identifies a gene, STE20, that encodes a putative kinase necessary for mating of Saccharomyces cerevisiae
    • Ramer, S.W. and Davis, R.W. (1993) A dominant truncation allele identifies a gene, STE20, that encodes a putative kinase necessary for mating of Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA, 90, 452-456.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 452-456
    • Ramer, S.W.1    Davis, R.W.2
  • 44
    • 0028308576 scopus 로고
    • Physical association between Src homology 3 elements and the protein product of the c-cbl proto-oncogene
    • Rivero-Lezcano,O.M., Sameshima, J.H., Marcilla, A. and Robbins, K.C. (1994) Physical association between Src homology 3 elements and the protein product of the c-cbl proto-oncogene. J. Biol. Chem., 269. 17363-17366.
    • (1994) J. Biol. Chem. , vol.269 , pp. 17363-17366
    • Rivero-Lezcano, O.M.1    Sameshima, J.H.2    Marcilla, A.3    Robbins, K.C.4
  • 45
    • 0029126878 scopus 로고
    • Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains
    • Rivero-Lezcano, O.M., Marcilla, A., Sameshima, J.H. and Robbins, K.C. (1995) Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains. Mol. Cell. Biol., 15, 5725-5731.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5725-5731
    • Rivero-Lezcano, O.M.1    Marcilla, A.2    Sameshima, J.H.3    Robbins, K.C.4
  • 46
    • 0344265606 scopus 로고
    • A vector for expressing GAL4(1-147) fusions in mammalian cells
    • Sadowski, I. and Ptashne, M. (1989) A vector for expressing GAL4(1-147) fusions in mammalian cells. Nucleic Acids Res., 17, 7539.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 7539
    • Sadowski, I.1    Ptashne, M.2
  • 47
    • 0028558986 scopus 로고
    • Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
    • Sanchez, I., Hughes, R.T., Mayer, B.J., Yee, K., Woodgett, J.R., Avruch, J., Kyriakis, J.M. and Zon, L.I. (1994) Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature, 372, 794-797.
    • (1994) Nature , vol.372 , pp. 794-797
    • Sanchez, I.1    Hughes, R.T.2    Mayer, B.J.3    Yee, K.4    Woodgett, J.R.5    Avruch, J.6    Kyriakis, J.M.7    Zon, L.I.8
  • 49
    • 0025921611 scopus 로고
    • Cloning of PI3-kinase associated p85 using a novel method for expression/cloning of target proteins for receptor tyrosine kinases
    • Skolnik, E.Y., Margolis, B., Mohammadi, M., Lowenstein, E., Fisher, R., Drepps, A., Ullrich, A. and Schlessinger, J. (1991) Cloning of PI3-kinase associated p85 using a novel method for expression/cloning of target proteins for receptor tyrosine kinases. Cell, 65, 83-91.
    • (1991) Cell , vol.65 , pp. 83-91
    • Skolnik, E.Y.1    Margolis, B.2    Mohammadi, M.3    Lowenstein, E.4    Fisher, R.5    Drepps, A.6    Ullrich, A.7    Schlessinger, J.8
  • 50
    • 0027288587 scopus 로고
    • Interaction of GRB-2/SEM-5 with insulin receptor substrate-1 (IRS-1) and Shc is implicated in insulin receptor-mediated Ras activation
    • Skolnik, E.Y. et al. (1993) Interaction of GRB-2/SEM-5 with insulin receptor substrate-1 (IRS-1) and Shc is implicated in insulin receptor-mediated Ras activation. EMBO J., 12, 1929-1936.
    • (1993) EMBO J. , vol.12 , pp. 1929-1936
    • Skolnik, E.Y.1
  • 51
    • 0030006284 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization
    • Symons, M., Derry, J.M., Karkak, B., Jiang, S., Lemajieu, V., McCormick, F., Francke, U. and Abo, A. (1996) Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization. Cell, 84, 723-724.
    • (1996) Cell , vol.84 , pp. 723-724
    • Symons, M.1    Derry, J.M.2    Karkak, B.3    Jiang, S.4    Lemajieu, V.5    McCormick, F.6    Francke, U.7    Abo, A.8
  • 52
    • 0028789982 scopus 로고
    • Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins
    • Tanaka, M., Gupta, R. and Mayer, B.J. (1995) Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins. Mol. Cell. Biol., 15, 6829-6837.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6829-6837
    • Tanaka, M.1    Gupta, R.2    Mayer, B.J.3
  • 53
    • 0027250250 scopus 로고
    • Mammalian Ras interacts directly with the serine/threonine kinase Raf
    • Voyjtek, A.B., Hollenberg, S.M. and Cooper, J.M. (1993) Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell, 74, 205-214.
    • (1993) Cell , vol.74 , pp. 205-214
    • Voyjtek, A.B.1    Hollenberg, S.M.2    Cooper, J.M.3
  • 54
    • 0029942952 scopus 로고    scopus 로고
    • Cloning of rat MEK Kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain
    • Xu, S., Robbins, D.J., Christerson, L.B., English, J.M., Vanderbilt, C.A. and Cobb, M.H. (1996) Cloning of rat MEK Kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain. Proc. Natl Acad. Sci. USA, 93, 5291-5295.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 5291-5295
    • Xu, S.1    Robbins, D.J.2    Christerson, L.B.3    English, J.M.4    Vanderbilt, C.A.5    Cobb, M.H.6
  • 55
    • 0028670788 scopus 로고
    • Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
    • Yan, M., Dia, T., Deak, J.C., Kyriakis, J.M., Zon, L.I., Woodgett, J.R. and Templeton, D.J. (1994) Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1. Nature, 372, 798-800.
    • (1994) Nature , vol.372 , pp. 798-800
    • Yan, M.1    Dia, T.2    Deak, J.C.3    Kyriakis, J.M.4    Zon, L.I.5    Woodgett, J.R.6    Templeton, D.J.7
  • 56
    • 0013484134 scopus 로고
    • Structural basis for the binding of proline-rich peptides to the SH3 domains
    • Yu, H., Chen, J.K., Feng, S., Dalgarno, D.C., Brauer, A.W. and Schreiber, S.L. (1994) Structural basis for the binding of proline-rich peptides to the SH3 domains. Cell, 76, 933-945.
    • (1994) Cell , vol.76 , pp. 933-945
    • Yu, H.1    Chen, J.K.2    Feng, S.3    Dalgarno, D.C.4    Brauer, A.W.5    Schreiber, S.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.