-
1
-
-
37249044261
-
First steps in establishing a developmental toxicity test method based on human embryonic stem cells
-
Adler, S., Pellizzer, C., Hareng, L., et al. (2008). First steps in establishing a developmental toxicity test method based on human embryonic stem cells. Toxicol In Vitro 22, 200-211.
-
(2008)
Toxicol in Vitro
, vol.22
, pp. 200-211
-
-
Adler, S.1
Pellizzer, C.2
Hareng, L.3
-
2
-
-
59449099932
-
Ketoconazole- and fluconazole-induced embryotoxicity and skeletal anomalies in wistar rats: A comparative study
-
Amaral, V. C. and Nunes, G. P. Jr. (2008). Ketoconazole- and fluconazole-induced embryotoxicity and skeletal anomalies in wistar rats: A comparative study. Brazilian Archives of Biology and Technology 51, 1153-1161.
-
(2008)
Brazilian Archives of Biology and Technology
, vol.51
, pp. 1153-1161
-
-
Amaral, V.C.1
Nunes Jr., G.P.2
-
3
-
-
68749100629
-
Prednisone reduces ketoconazole-induced skeletal defects in rat fetuses
-
Amaral, V. C. and Nunes, G. P. Jr. (2009). Prednisone reduces ketoconazole-induced skeletal defects in rat fetuses. Arch Toxicol 83, 863-871.
-
(2009)
Arch Toxicol
, vol.83
, pp. 863-871
-
-
Amaral, V.C.1
Nunes Jr., G.P.2
-
4
-
-
0037082643
-
Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro
-
Andersen, H. R., Vinggaard, A. M., Rasmussen, T. H., et al. (2002). Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro. Toxicol Appl Pharmacol 179, 1-12.
-
(2002)
Toxicol Appl Pharmacol
, vol.179
, pp. 1-12
-
-
Andersen, H.R.1
Vinggaard, A.M.2
Rasmussen, T.H.3
-
5
-
-
0023228346
-
Inhibition of rat testicular 17 alpha-hydroxylase and 17,20-lyase activities by anti-androgens (flutamide, hydroxyflutamide, RU23908, cyproterone acetate) in vitro
-
Ayub, M. and Levell, M. J. (1987). Inhibition of rat testicular 17 alpha-hydroxylase and 17,20-lyase activities by anti-androgens (flutamide, hydroxyflutamide, RU23908, cyproterone acetate) in vitro. J Steroid Biochem 28, 43-47.
-
(1987)
J Steroid Biochem
, vol.28
, pp. 43-47
-
-
Ayub, M.1
Levell, M.J.2
-
6
-
-
0023747159
-
Structure-activity relationships of the inhibition of human placental aromatase by imidazole drugs including ketoconazole
-
Ayub, M. and Levell, M. J. (1988). Structure-activity relationships of the inhibition of human placental aromatase by imidazole drugs including ketoconazole. J Steroid Biochem 31, 65-72.
-
(1988)
J Steroid Biochem
, vol.31
, pp. 65-72
-
-
Ayub, M.1
Levell, M.J.2
-
7
-
-
0023180034
-
Teratogenicity in vitro - A comparative study of four antimycotic drugs using the whole-embryo culture system
-
Bechter, R. and Schmid, B. P. (1987). Teratogenicity in vitro - A comparative study of four antimycotic drugs using the whole-embryo culture system. Toxicol In Vitro 1, 11-15.
-
(1987)
Toxicol in Vitro
, vol.1
, pp. 11-15
-
-
Bechter, R.1
Schmid, B.P.2
-
8
-
-
84883881637
-
-
Becker, , External Scientific Report: Identification of cumulative assessment groups of pesticides (accessed 05.11.2012).
-
Becker 1988). CAPEG Database V1.2 and User Guide, External Scientific Report: Identification of cumulative assessment groups of pesticides http://www.efsa.europa.eu/en/supporting/pub/269e.htm (accessed 05.11.2012).
-
(1988)
CAPEG Database V1.2 and User Guide
-
-
-
9
-
-
85039637606
-
Embryotoxicity study (including teratogenicity) with Prochloraz Technical in the rabbit (main study
-
Council Directive 91/414/EEC
-
Becker, H., Mueller, E., Vogel, W., et al. (1988). Embryotoxicity study (including teratogenicity) with Prochloraz Technical in the rabbit (main study). Draft Assessment Report. Initial risk assessment report provided by rappoteur member state Ireland for the existing active substance PROCHLORAZ of the third stage (part B) of the review programme referred to in Article 8(2) of Council Directive 91/414/EEC.
-
(1988)
Draft Assessment Report. Initial Risk Assessment Report Provided by Rappoteur Member State Ireland for the Existing Active Substance PROCHLORAZ of the Third Stage (Part B) of the Review Programme Referred to in Article
, vol.8
, pp. 2
-
-
Becker, H.1
Mueller, E.2
Vogel, W.3
-
10
-
-
84883862135
-
-
External Scientific Report: Identification of cumulative assessment groups of pesticides (accessed 05.11.2012).
-
Becker and Biedermann 1995). CAPEG Database V1.2 and User Guide, External Scientific Report: Identification of cumulative assessment groups of pesticides http://www.efsa.europa.eu/en/supporting/pub/269e.htm (accessed 05.11.2012).
-
Becker and Biedermann 1995). CAPEG Database V1.2 and User Guide
-
-
-
12
-
-
7444221917
-
The combined antiandrogenic effects of five commonly used pesticides
-
Birkhoj, M., Nellemann, C., Jarfelt, K., et al. (2004). The combined antiandrogenic effects of five commonly used pesticides. Toxicol Appl Pharmacol 201, 10-20.
-
(2004)
Toxicol Appl Pharmacol
, vol.201
, pp. 10-20
-
-
Birkhoj, M.1
Nellemann, C.2
Jarfelt, K.3
-
13
-
-
77953592110
-
Characterization of the androgen-sensitive MDA-kb2 cell line for assessing complex environmental mixtures
-
Blake, L. S., Martinovic, D., Gray, L. E. Jr., et al. (2010). Characterization of the androgen-sensitive MDA-kb2 cell line for assessing complex environmental mixtures. Environ Toxicol Chem 29, 1367-1376.
-
(2010)
Environ Toxicol Chem
, vol.29
, pp. 1367-1376
-
-
Blake, L.S.1
Martinovic, D.2
Gray Jr., L.E.3
-
14
-
-
34447566135
-
Sensitivity of fetal rat testicular steroidogenesis to maternal prochloraz exposure and the underlying mechanism of inhibition
-
Blystone, C. R., Lambright, C. S., Howdeshell, K. L., et al. (2007). Sensitivity of fetal rat testicular steroidogenesis to maternal prochloraz exposure and the underlying mechanism of inhibition. Toxicol Sci 97, 512-519.
-
(2007)
Toxicol Sci
, vol.97
, pp. 512-519
-
-
Blystone, C.R.1
Lambright, C.S.2
Howdeshell, K.L.3
-
15
-
-
27744491638
-
Effect of pesticides on estrogen receptor transactivation in vitro: A comparison of stable transfected MVLN and transient transfected MCF-7 cells
-
Bonefeld-Jorgensen, E. C., Grunfeld, H. T., and Gjermandsen, I. M. (2005). Effect of pesticides on estrogen receptor transactivation in vitro: a comparison of stable transfected MVLN and transient transfected MCF-7 cells. Mol Cell Endocrinol 244, 20-30.
-
(2005)
Mol Cell Endocrinol
, vol.244
, pp. 20-30
-
-
Bonefeld-Jorgensen, E.C.1
Grunfeld, H.T.2
Gjermandsen, I.M.3
-
16
-
-
84883894348
-
-
Borders1 1985), External Scientific Report: Identification of cumulative assessment groups of pesticides (accessed 05.11.2012).
-
Borders1 1985). CAPEG Database V1.2 and User Guide, External Scientific Report: Identification of cumulative assessment groups of pesticides http://www.efsa.europa.eu/en/supporting/pub/269e.htm (accessed 05.11.2012).
-
CAPEG Database V1.2 and User Guide
-
-
-
17
-
-
79958158241
-
Evaluation of 309 environmental chemicals using a mouse embryonic stem cell adherent cell differentiation and cytotoxicity assay
-
Chandler, K. J., Barrier, M., Jeffay, S., et al. (2011). Evaluation of 309 environmental chemicals using a mouse embryonic stem cell adherent cell differentiation and cytotoxicity assay. PloS One 6, e18540.
-
(2011)
PloS One
, vol.6
-
-
Chandler, K.J.1
Barrier, M.2
Jeffay, S.3
-
18
-
-
85039642016
-
-
Initial risk assessment report provided by rappoteur member state Ireland for the existing active substance PROCHLORAZ of the third stage (part B of the review programme referred to in Article 8 2) of Council Directive 91/414/EEC
-
Cozens, D. D. (1982). The effect of BTS 40 542 on reproductive function of multiple generations in the rat. Draft Assessment Report. Initial risk assessment report provided by rappoteur member state Ireland for the existing active substance PROCHLORAZ of the third stage (part B) of the review programme referred to in Article 8(2) of Council Directive 91/414/EEC.
-
(1982)
The Effect of BTS 40 542 on Reproductive Function of Multiple Generations in the Rat. Draft Assessment Report
-
-
Cozens, D.D.1
-
19
-
-
85033509641
-
Ketoconazole impairs early pregnancy and the decidual cell response via alterations in ovarian function
-
Cummings, A. M., Hedge, J. L., and Laskey, J. (1997). Ketoconazole impairs early pregnancy and the decidual cell response via alterations in ovarian function. Fundam Appl Toxicol 40, 238-246.
-
(1997)
Fundam Appl Toxicol
, vol.40
, pp. 238-246
-
-
Cummings, A.M.1
Hedge, J.L.2
Laskey, J.3
-
20
-
-
34447262150
-
Embryonic cardiac arrhythmia and generation of reactive oxygen species: Common teratogenic mechanism for IKr blocking drugs
-
Danielsson, B. R., Danielsson, C., and Nilsson, M. F. (2007). Embryonic cardiac arrhythmia and generation of reactive oxygen species: common teratogenic mechanism for IKr blocking drugs. Reprod Toxicol 24, 42-56.
-
(2007)
Reprod Toxicol
, vol.24
, pp. 42-56
-
-
Danielsson, B.R.1
Danielsson, C.2
Nilsson, M.F.3
-
21
-
-
84860242065
-
Prenatal epoxiconazole exposure effects on rat postnatal development
-
de Castro, V. L. and Maia, A. H. (2012). Prenatal epoxiconazole exposure effects on rat postnatal development. Birth Defects Res B Dev Reprod Toxicol 95, 123-129.
-
Birth Defects Res B Dev Reprod Toxicol
, vol.95
, Issue.2012
, pp. 123-129
-
-
De Castro, V.L.1
Maia, A.H.2
-
22
-
-
79955604503
-
Comparison of the mouse Embryonic Stem Cell Test, the rat Whole Embryo Culture and the Zebrafish Embryotoxicity Test as alternative methods for developmental toxicity testing of six 1,2,4-triazoles
-
de Jong, E., Barenys, M., Hermsen, S. A., et al. (2011). Comparison of the mouse Embryonic Stem Cell Test, the rat Whole Embryo Culture and the Zebrafish Embryotoxicity Test as alternative methods for developmental toxicity testing of six 1,2,4-triazoles. Toxicol Appl Pharmacol 253, 103-111.
-
(2011)
Toxicol Appl Pharmacol
, vol.253
, pp. 103-111
-
-
De Jong, E.1
Barenys, M.2
Hermsen, S.A.3
-
23
-
-
0024272784
-
Comparative effects of ketoconazole on rat, dog and human testicular steroidogenesis
-
De Coster, R., Coene, M. C., Van Camp, C., et al. (1989). Comparative effects of ketoconazole on rat, dog and human testicular steroidogenesis. J Enzyme Inhib 2, 261-268.
-
(1989)
J Enzyme Inhib
, vol.2
, pp. 261-268
-
-
De Coster, R.1
Coene, M.C.2
Van Camp, C.3
-
24
-
-
79960837213
-
Is the amphibian X. Laevis WEC a good alternative method to rodent WEC teratogenicity assay? the example of the three triazole derivative fungicides Triadimefon, Tebuconazole, Cyproconazole
-
Di Renzo, F., Bacchetta, R., Bizzo, A., et al. (2011). Is the amphibian X. laevis WEC a good alternative method to rodent WEC teratogenicity assay? The example of the three triazole derivative fungicides Triadimefon, Tebuconazole, Cyproconazole. Reprod Toxicol 32, 220-226.
-
(2011)
Reprod Toxicol
, vol.32
, pp. 220-226
-
-
Di Renzo, F.1
Bacchetta, R.2
Bizzo, A.3
-
25
-
-
84878346786
-
Prenatal prochloraz treatment significantly increases pregnancy length and reduces offspring weight but does not affect social-olfactory memory in rats
-
Dmytriyeva, O., Klementiev, B., Berezin, V., et al. (2013). Prenatal prochloraz treatment significantly increases pregnancy length and reduces offspring weight but does not affect social-olfactory memory in rats. Exp Toxicol Pathol 65, 591-3.
-
(2013)
Exp Toxicol Pathol
, vol.65
, pp. 591-593
-
-
Dmytriyeva, O.1
Klementiev, B.2
Berezin, V.3
-
26
-
-
84883894348
-
-
Eiben 1987), External Scientific Report: Identification of cumulative assessment groups of pesticides, (accessed 05.11.2012).
-
Eiben 1987). CAPEG Database V1.2 and User Guide, External Scientific Report: Identification of cumulative assessment groups of pesticides http://www.efsa.europa.eu/en/supporting/pub/269e.htm (accessed 05.11.2012).
-
CAPEG Database V1.2 and User Guide
-
-
-
27
-
-
0017597209
-
Uncoupling of vaginal opening and the first ovulation - An indication of an alteration in the pituitary-gonadal axis
-
Firlit, M. G. and Schwartz, N. B. (1977). Uncoupling of vaginal opening and the first ovulation - an indication of an alteration in the pituitary-gonadal axis. Biol Reprod 16, 441-444.
-
(1977)
Biol Reprod
, vol.16
, pp. 441-444
-
-
Firlit, M.G.1
Schwartz, N.B.2
-
28
-
-
84861465078
-
BLTK1 murine Leydig cells: A novel steroidogenic model for evaluating the effects of reproductive and developmental toxicants
-
Forgacs, A. L., Ding, Q., Jaremba, R. G., et al. (2012). BLTK1 murine Leydig cells: A novel steroidogenic model for evaluating the effects of reproductive and developmental toxicants. Toxicol Sci 127, 391-402.
-
(2012)
Toxicol Sci
, vol.127
, pp. 391-402
-
-
Forgacs, A.L.1
Ding, Q.2
Jaremba, R.G.3
-
29
-
-
0023178993
-
Ovine placental aromatase: Studies of activity levels, kinetic characteristics and effects of aromatase inhibitors
-
France, J. T., Mason, J. I., Magness, R. R., et al. (1987). Ovine placental aromatase: studies of activity levels, kinetic characteristics and effects of aromatase inhibitors. J Steroid Biochem 28, 155-160.
-
(1987)
J Steroid Biochem
, vol.28
, pp. 155-160
-
-
France, J.T.1
Mason, J.I.2
Magness, R.R.3
-
30
-
-
0036098620
-
The ECVAM international validation study on in vitro embryotoxicity tests: Results of the definitive phase and evaluation of prediction models. European Centre for the Validation of Alternative Methods
-
Genschow, E., Spielmann, H., Scholz, G., et al. (2002). The ECVAM international validation study on in vitro embryotoxicity tests: results of the definitive phase and evaluation of prediction models. European Centre for the Validation of Alternative Methods. Altern Lab Anim 30, 151-176.
-
(2002)
Altern Lab Anim
, vol.30
, pp. 151-176
-
-
Genschow, E.1
Spielmann, H.2
Scholz, G.3
-
31
-
-
8744223170
-
Validation of the embryonic stem cell test in the international ECVAM validation study on three in vitro embryotoxicity tests
-
Genschow, E., Spielmann, H., Scholz, G., et al. (2004). Validation of the embryonic stem cell test in the international ECVAM validation study on three in vitro embryotoxicity tests. Altern Lab Anim 32, 209-244.
-
(2004)
Altern Lab Anim
, vol.32
, pp. 209-244
-
-
Genschow, E.1
Spielmann, H.2
Scholz, G.3
-
32
-
-
77955920494
-
Are azole fungicides a teratogenic risk for human conceptus?
-
Giavini, E. and Menegola, E. (2010). Are azole fungicides a teratogenic risk for human conceptus? Toxicol Lett 198, 106-111.
-
(2010)
Toxicol Lett
, vol.198
, pp. 106-111
-
-
Giavini, E.1
Menegola, E.2
-
33
-
-
33845656069
-
Disruption of testosterone homeostasis as a mode of action for the reproduce tive toxicity of triazole fungicides in the male rat
-
Goetz, A. K., Ren, H., Schmid, J. E., et al. (2007). Disruption of testosterone homeostasis as a mode of action for the reproduce tive toxicity of triazole fungicides in the male rat. Toxicol Sci 95, 227-239.
-
(2007)
Toxicol Sci
, vol.95
, pp. 227-239
-
-
Goetz, A.K.1
Ren, H.2
Schmid, J.E.3
-
34
-
-
72949088372
-
Inhibition of rat and human steroidogenesis by triazole antifungals
-
Goetz, A. K., Rockett, J. C., Ren, H., et al. (2009). Inhibition of rat and human steroidogenesis by triazole antifungals. Syst Biol Reprod Med 55, 214-226.
-
(2009)
Syst Biol Reprod Med
, vol.55
, pp. 214-226
-
-
Goetz, A.K.1
Rockett, J.C.2
Ren, H.3
-
35
-
-
84863996698
-
Adverse effects on sexual development in rat offspring after low dose exposure to a mixture of endocrine disrupting pesticides
-
Hass, U., Boberg, J., Christiansen, S., et al. (2012). Adverse effects on sexual development in rat offspring after low dose exposure to a mixture of endocrine disrupting pesticides. Reprod Toxicol 34, 261-74.
-
(2012)
Reprod Toxicol
, vol.34
, pp. 261-274
-
-
Hass, U.1
Boberg, J.2
Christiansen, S.3
-
36
-
-
33750351770
-
Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: Hormone production
-
Hecker, M., Newsted, J. L., Murphy, M. B., et al. (2006). Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: hormone production. Toxicol Appl Pharmacol 217, 114-124.
-
(2006)
Toxicol Appl Pharmacol
, vol.217
, pp. 114-124
-
-
Hecker, M.1
Newsted, J.L.2
Murphy, M.B.3
-
38
-
-
85039634997
-
-
Study of the prenatal toxicity of Reg 205 259 in rabbits after oral administration (gavage (accessed 05.11.2012
-
Hellwig, J. and Hildebrand, B. (1990a). Annex XV Dossier: Proposal for harmonised classification and labelling. Study of the prenatal toxicity of Reg. 205 259 in rabbits after oral administration (gavage). http://echa.europa.eu/ documents/10162/f39183f6-ef29-40ae-a274-8c1c197d5f9e (accessed 05.11.2012).
-
(1990)
Annex XV Dossier: Proposal for Harmonised Classification and Labelling
-
-
Hellwig, J.1
Hildebrand, B.2
-
39
-
-
84883893638
-
-
External Scientific Report: Identification of cumulative assessment groups of pesticides (accessed 05.11.2012
-
Hellwig, J. and Hildebrand, B. (1990b). CAPEG Database V1.2 and User Guide, External Scientific Report: Identification of cumulative assessment groups of pesticides. http://www.efsa.europa.eu/en/supporting/pub/269e.htm (accessed 05.11.2012).
-
(1990)
CAPEG Database V1.2 and User Guide
-
-
Hellwig, J.1
Hildebrand, B.2
-
41
-
-
0345276652
-
A comparison of human H295R and rat R2C cell lines as in vitro screening tools for effects on aromatase
-
Heneweer, M., van den Berg, M., and Sanderson, J. T. (2004). A comparison of human H295R and rat R2C cell lines as in vitro screening tools for effects on aromatase. Toxicol Lett 146, 183-194.
-
(2004)
Toxicol Lett
, vol.146
, pp. 183-194
-
-
Heneweer, M.1
Van Den Berg, M.2
Sanderson, J.T.3
-
42
-
-
79952040775
-
Relative embryotoxicity of two classes of chemicals in a modified zebrafish embryotoxicity test and comparison with their in vivo potencies
-
Hermsen, S. A., van den Brandhof, E. J., van der Ven, L. T., and Piersma, A. H. (2011). Relative embryotoxicity of two classes of chemicals in a modified zebrafish embryotoxicity test and comparison with their in vivo potencies. Toxicol In Vitro 25, 745-753.
-
(2011)
Toxicol in Vitro
, vol.25
, pp. 745-753
-
-
Hermsen, S.A.1
Van Den Brandhof, E.J.2
Van Der Ven, L.T.3
Piersma, A.H.4
-
43
-
-
77952671420
-
Assessment of chemical effects on aromatase activity using the H295R cell line
-
Higley, E. B., Newsted, J. L., Zhang, X., et al. (2010). Assessment of chemical effects on aromatase activity using the H295R cell line. Environ Sci Pollut Res Int 17, 1137-1148.
-
(2010)
Environ Sci Pollut Res Int
, vol.17
, pp. 1137-1148
-
-
Higley, E.B.1
Newsted, J.L.2
Zhang, X.3
-
45
-
-
84864023143
-
Persistent developmental toxicity in rat offspring after low dose exposure to a mixture of endocrine disrupting pesticides
-
Jacobsen, P. R., Axelstad, M., and Boberg, J. (2012). Persistent developmental toxicity in rat offspring after low dose exposure to a mixture of endocrine disrupting pesticides. Reprod Toxicol 34, 237-250.
-
(2012)
Reprod Toxicol
, vol.34
, pp. 237-250
-
-
Jacobsen, P.R.1
Axelstad, M.2
Boberg, J.3
-
46
-
-
0034837182
-
The fungicide propiconazole interferes with embryonic development of the crustacean Daphnia magna
-
Kast-Hutcheson, K., Rider, C. V., and LeBlanc, G. A. (2001). The fungicide propiconazole interferes with embryonic development of the crustacean Daphnia magna. Environ Toxicol Chem 20, 502-509.
-
(2001)
Environ Toxicol Chem
, vol.20
, pp. 502-509
-
-
Kast-Hutcheson, K.1
Rider, C.V.2
Leblanc, G.A.3
-
47
-
-
79955789073
-
Effects of azole fungicides on the function of sex and thyroid hormones
-
Report for the Danish Environmental Protection Agency
-
Kjaerstad, M. B., et al. (2007). Effects of azole fungicides on the function of sex and thyroid hormones. Pesticides Research No. 111, Report for the Danish Environmental Protection Agency.
-
(2007)
Pesticides Research
, Issue.111
-
-
Kjaerstad, M.B.1
-
48
-
-
77949586144
-
Mixture effects of endocrine disrupting compounds in vitro
-
Kjaerstad, M. B., Taxvig, C., Andersen, H. R., et al. (2010a). Mixture effects of endocrine disrupting compounds in vitro. Int J Androl 33, 425-433.
-
(2010)
Int J Androl
, vol.33
, pp. 425-433
-
-
Kjaerstad, M.B.1
Taxvig, C.2
Andersen, H.R.3
-
49
-
-
78649477675
-
Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals
-
Kjaerstad, M. B., Taxvig, C., Nellemann, C., et al. (2010b). Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals. Reprod Toxicol 30, 573-582.
-
(2010)
Reprod Toxicol
, vol.30
, pp. 573-582
-
-
Kjaerstad, M.B.1
Taxvig, C.2
Nellemann, C.3
-
50
-
-
0036443388
-
Assessing pregnancy risks of azole antifungals using a high throughput aromatase inhibition assay
-
Kragie, L., Turner, S. D., Patten, C. J., et al. (2002). Assessing pregnancy risks of azole antifungals using a high throughput aromatase inhibition assay. Endocr Res 28, 129-140.
-
(2002)
Endocr Res
, vol.28
, pp. 129-140
-
-
Kragie, L.1
Turner, S.D.2
Patten, C.J.3
-
51
-
-
0027725071
-
Validation of whole chick embryo cultures, whole rat embryo cultures and aggregating embryonic brain cell cultures using six pairs of coded compounds
-
Kucera, P., Cano, E., Honegger, P., et al. (1993). Validation of whole chick embryo cultures, whole rat embryo cultures and aggregating embryonic brain cell cultures using six pairs of coded compounds. Toxicol In Vitro 7, 785-798.
-
(1993)
Toxicol in Vitro
, vol.7
, pp. 785-798
-
-
Kucera, P.1
Cano, E.2
Honegger, P.3
-
52
-
-
84866517272
-
Embryonic stem cell test: Stem cell use in predicting developmental cardiotoxicity and osteotoxicity
-
Kuske, B., Pulyanina, P. Y., and zur Nieden, N. I. (2012). Embryonic stem cell test: stem cell use in predicting developmental cardiotoxicity and osteotoxicity. Methods Mol Biol 889, 147-179.
-
(2012)
Methods Mol Biol
, vol.889
, pp. 147-179
-
-
Kuske, B.1
Pulyanina, P.Y.2
Zur Nieden, N.I.3
-
53
-
-
33646807130
-
Mechanisms of action underlying the antiandrogenic effects of the fungicide prochloraz
-
Laier, P., Metzdorff, S. B., Borch, J., et al. (2006). Mechanisms of action underlying the antiandrogenic effects of the fungicide prochloraz. Toxicol Appl Pharmacol 213, 160-171.
-
(2006)
Toxicol Appl Pharmacol
, vol.213
, pp. 160-171
-
-
Laier, P.1
Metzdorff, S.B.2
Borch, J.3
-
54
-
-
60749089958
-
Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production
-
Lambrot, R., Muczynski, V., Lecureuil, C., et al. (2009). Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production. Environ Health Perspect 117, 32-37.
-
(2009)
Environ Health Perspect
, vol.117
, pp. 32-37
-
-
Lambrot, R.1
Muczynski, V.2
Lecureuil, C.3
-
55
-
-
33750009766
-
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line
-
Laville, N., Balaguer, P., Brion, F., et al. (2006). Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line. Toxicology 228, 98-108.
-
(2006)
Toxicology
, vol.228
, pp. 98-108
-
-
Laville, N.1
Balaguer, P.2
Brion, F.3
-
56
-
-
0242494051
-
Effects of currently used pesticides in the AhR-CALUXassay: Comparison between the human TV101L and the rat H4IIE cell line
-
Long, M., Laier, P., Vinggaard, A. M., et al. (2003). Effects of currently used pesticides in the AhR-CALUXassay: comparison between the human TV101L and the rat H4IIE cell line. Toxicology 194, 77-93.
-
(2003)
Toxicology
, vol.194
, pp. 77-93
-
-
Long, M.1
Laier, P.2
Vinggaard, A.M.3
-
59
-
-
69849088915
-
A review of the implementation of the embryonic stem cell test (EST). The report and recommendations of an ECVAM/ReProTect Workshop
-
Marx-Stoelting, P., Adriaens, E., Ahr, H. J., et al. (2009). A review of the implementation of the embryonic stem cell test (EST). The report and recommendations of an ECVAM/ReProTect Workshop. Altern Lab Anim 37, 313-328.
-
(2009)
Altern Lab Anim
, vol.37
, pp. 313-328
-
-
Marx-Stoelting, P.1
Adriaens, E.2
Ahr, H.J.3
-
60
-
-
0021802377
-
Imidazole antimycotics: Inhibitors of steroid aromatase
-
Mason, J. I., Murry, B. A., Olcott, M., et al. (1985). Imidazole antimycotics: inhibitors of steroid aromatase. Biochem Pharmacol 34, 1087-1092.
-
(1985)
Biochem Pharmacol
, vol.34
, pp. 1087-1092
-
-
Mason, J.I.1
Murry, B.A.2
Olcott, M.3
-
61
-
-
0023479804
-
Imidazole antimycotics: Selective inhibitors of steroid aromatization and progesterone hydroxylation
-
Mason, J. I., Carr, B. R., and Murry, B. A. (1987). Imidazole antimycotics: selective inhibitors of steroid aromatization and progesterone hydroxylation. Steroids 50, 179-189.
-
(1987)
Steroids
, vol.50
, pp. 179-189
-
-
Mason, J.I.1
Carr, B.R.2
Murry, B.A.3
-
62
-
-
30044439387
-
Dysmorphogenic effects of some fungicides derived from the imidazole on rat embryos cultured in vitro
-
Menegola, E., Broccia, M. L., Di Renzo, F., et al. (2006). Dysmorphogenic effects of some fungicides derived from the imidazole on rat embryos cultured in vitro. Reprod Toxicol 21, 74-82.
-
(2006)
Reprod Toxicol
, vol.21
, pp. 74-82
-
-
Menegola, E.1
Broccia, M.L.2
Di Renzo, F.3
-
63
-
-
84855228517
-
Malformation spectrum induced by ketoconazole after single administration to pregnant rats during the critical period - Comparison with vitamin A-induced malformation spectrum
-
Mineshima, H., Fukuta, T., Kato, E., et al. (2012). Malformation spectrum induced by ketoconazole after single administration to pregnant rats during the critical period - comparison with vitamin A-induced malformation spectrum. J Appl Toxicol 32, 98-107.
-
(2012)
J Appl Toxicol
, vol.32
, pp. 98-107
-
-
Mineshima, H.1
Fukuta, T.2
Kato, E.3
-
64
-
-
0034899131
-
The effects of perinatal tebuconazole exposure on adult neurological, immunological, and reproductive function in rats
-
Moser, V. C., Barone, S. Jr., Smialowicz, R. J., et al. (2001). The effects of perinatal tebuconazole exposure on adult neurological, immunological, and reproductive function in rats. Toxicol Sci 62, 339-352.
-
(2001)
Toxicol Sci
, vol.62
, pp. 339-352
-
-
Moser, V.C.1
Barone Jr., S.2
Smialowicz, R.J.3
-
66
-
-
84856432457
-
H295R cells as a model for steroidogenic disruption: A broader perspective using simultaneous chemical analysis of 7 key steroid hormones
-
Nielsen, F. K., Hansen, C. H., Fey, J. A., et al. (2012). H295R cells as a model for steroidogenic disruption: a broader perspective using simultaneous chemical analysis of 7 key steroid hormones. Toxicol In Vitro 26, 343-350.
-
(2012)
Toxicol in Vitro
, vol.26
, pp. 343-350
-
-
Nielsen, F.K.1
Hansen, C.H.2
Fey, J.A.3
-
67
-
-
18844429502
-
Late gestational exposure to the fungicide prochloraz delays the onset of parturition and causes reproductive malformations in male but not female rat offspring
-
Noriega, N. C., Ostby, J., Lambright, C., et al. (2005). Late gestational exposure to the fungicide prochloraz delays the onset of parturition and causes reproductive malformations in male but not female rat offspring. Biol Reprod 72, 1324-1335.
-
(2005)
Biol Reprod
, vol.72
, pp. 1324-1335
-
-
Noriega, N.C.1
Ostby, J.2
Lambright, C.3
-
68
-
-
77954817430
-
Mixture effects of imidazole fungicides on cortisol and aldosterone secretion in human adrenocortical H295R cells
-
Ohlsson, A., Cedergreen, N., Oskarsson, A., et al. (2010). Mixture effects of imidazole fungicides on cortisol and aldosterone secretion in human adrenocortical H295R cells. Toxicology 275, 21-28.
-
(2010)
Toxicology
, vol.275
, pp. 21-28
-
-
Ohlsson, A.1
Cedergreen, N.2
Oskarsson, A.3
-
69
-
-
9944266190
-
A novel nonradioactive method for measuring aromatase activity using a human ovarian granulosa-like tumor cell line and an estrone ELISA
-
Ohno, K., Araki, N., Yanase, T., et al. (2004). A novel nonradioactive method for measuring aromatase activity using a human ovarian granulosa-like tumor cell line and an estrone ELISA. Toxicol Sci 82, 443-450.
-
(2004)
Toxicol Sci
, vol.82
, pp. 443-450
-
-
Ohno, K.1
Araki, N.2
Yanase, T.3
-
70
-
-
84948006407
-
Ketoconazole blocks testosterone synthesis
-
Pont, A., Williams, P. L., Azhar, S., et al. (1982). Ketoconazole blocks testosterone synthesis. Arch Intern Med 142, 2137-2140.
-
(1982)
Arch Intern Med
, vol.142
, pp. 2137-2140
-
-
Pont, A.1
Williams, P.L.2
Azhar, S.3
-
72
-
-
79955475110
-
Defined culture medium for stem cell differentiation: Applicability of serum-free conditions in the mouse embryonic stem cell test
-
Riebeling, C., Schlechter, K., Buesen, R., et al. (2011). Defined culture medium for stem cell differentiation: applicability of serum-free conditions in the mouse embryonic stem cell test. Toxicol In Vitro 25, 914-921.
-
(2011)
Toxicol in Vitro
, vol.25
, pp. 914-921
-
-
Riebeling, C.1
Schlechter, K.2
Buesen, R.3
-
73
-
-
84865255041
-
Screening for modulatory effects on steroidogenesis using the human H295R adrenocortical cell line: A metabolomics approach
-
Rijk, J. C., Peijnenburg, A. A., Blokland, M. H., et al. (2012). Screening for modulatory effects on steroidogenesis using the human H295R adrenocortical cell line: A metabolomics approach. Chem Res Toxicol 25, 1720-1731.
-
(2012)
Chem Res Toxicol
, vol.25
, pp. 1720-1731
-
-
Rijk, J.C.1
Peijnenburg, A.A.2
Blokland, M.H.3
-
74
-
-
33749595073
-
Effect of conazole fungicides on reproductive development in the female rat
-
Rockett, J. C., Narotsky, M. G., Thompson, K. E., et al. (2006). Effect of conazole fungicides on reproductive development in the female rat. Reprod Toxicol 22, 647-658.
-
(2006)
Reprod Toxicol
, vol.22
, pp. 647-658
-
-
Rockett, J.C.1
Narotsky, M.G.2
Thompson, K.E.3
-
75
-
-
0036070511
-
Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells
-
Sanderson, J. T., Boerma, J., Lansbergen, G. W., et al. (2002). Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells. Toxicol Appl Pharmacol 182, 44-54.
-
(2002)
Toxicol Appl Pharmacol
, vol.182
, pp. 44-54
-
-
Sanderson, J.T.1
Boerma, J.2
Lansbergen, G.W.3
-
76
-
-
85039636244
-
-
BAS 480 F - Maternal toxicity study in Wistar rats - Oral administration (gavage, Accessed 05.11.2012
-
Schneider, S. (2001). Annex XV Dossier: Proposal for harmonised classification and labelling. BAS 480 F - Maternal toxicity study in Wistar rats - Oral administration (gavage). http://echa.europa.eu/documents/10162/f39183f6- ef29-40ae-a274-8c1c197d5f9e (accessed 05.11.2012).
-
(2001)
Annex XV Dossier: Proposal for Harmonised Classification and Labeling
-
-
Schneider, S.1
-
78
-
-
0021331551
-
Effect of ketoconazole and other imidazole fungicides on testosterone biosynthesis
-
Schurmeyer, T. and Nieschlag, E. (1984). Effect of ketoconazole and other imidazole fungicides on testosterone biosynthesis. Acta Endocrinol (Copenh) 105, 275-280.
-
(1984)
Acta Endocrinol (Copenh
, vol.105
, pp. 275-280
-
-
Schurmeyer, T.1
Nieschlag, E.2
-
79
-
-
33747618281
-
Use of murine embryonic stem cells in embryotoxicity assays: The embryonic stem cell test
-
Seiler, A. E., Buesen, R., Visan, A., et al. (2006). Use of murine embryonic stem cells in embryotoxicity assays: the embryonic stem cell test. Methods Mol Biol 329, 371-395.
-
(2006)
Methods Mol Biol
, vol.329
, pp. 371-395
-
-
Seiler, A.E.1
Buesen, R.2
Visan, A.3
-
80
-
-
79959877538
-
The validated embryonic stem cell test to predict embryotoxicity in vitro
-
Seiler, A. E. and Spielmann, H. (2011). The validated embryonic stem cell test to predict embryotoxicity in vitro. Nat Protoc 6, 961-978.
-
(2011)
Nat Protoc
, vol.6
, pp. 961-978
-
-
Seiler, A.E.1
Spielmann, H.2
-
81
-
-
0034633287
-
A high-throughput screen to identify inhibitors of aromatase (CYP19
-
Stresser, D. M., Turner, S. D., McNamara, J., et al. (2000). A high-throughput screen to identify inhibitors of aromatase (CYP19). Anal Biochem 284, 427-430.
-
(2000)
Anal Biochem
, vol.284
, pp. 427-430
-
-
Stresser, D.M.1
Turner, S.D.2
McNamara, J.3
-
82
-
-
53449100719
-
Embryotoxicity hazard assessment of cadmium and arsenic compounds using embryonic stem cells
-
Stummann, T. C., Hareng, L., and Bremer, S. (2008). Embryotoxicity hazard assessment of cadmium and arsenic compounds using embryonic stem cells. Toxicology 252, 118-122.
-
(2008)
Toxicology
, vol.252
, pp. 118-122
-
-
Stummann, T.C.1
Hareng, L.2
Bremer, S.3
-
83
-
-
84866030472
-
Blockade of K+ and Ca2+ channels by azole antifungal agents in neonatal rat ventricular myocytes
-
Sung, D. J., Kim, J. G., Won, K. J., et al. (2012). Blockade of K+ and Ca2+ channels by azole antifungal agents in neonatal rat ventricular myocytes. Biol Pharm Bull 35, 1469-1475.
-
(2012)
Biol Pharm Bull
, vol.35
, pp. 1469-1475
-
-
Sung, D.J.1
Kim, J.G.2
Won, K.J.3
-
84
-
-
55649118438
-
In vitro screening for aryl hydrocarbon receptor agonistic activity in 200 pesticides using a highly sensitive reporter cell line, DR-EcoScreen cells, and in vivo mouse liver cytochrome P450-1A induction by propanil, diuron and linuron
-
Takeuchi, S., Iida, M., Yabushita, H., et al. (2008). In vitro screening for aryl hydrocarbon receptor agonistic activity in 200 pesticides using a highly sensitive reporter cell line, DR-EcoScreen cells, and in vivo mouse liver cytochrome P450-1A induction by propanil, diuron and linuron. Chemosphere 74, 155-165.
-
(2008)
Chemosphere
, vol.74
, pp. 155-165
-
-
Takeuchi, S.1
Iida, M.2
Yabushita, H.3
-
85
-
-
36248999429
-
Endocrine-disrupting activities in vivo of the fungicides tebuconazole and epoxiconazole
-
Taxvig, C., Hass, U., Axelstad, M., et al. (2007). Endocrine-disrupting activities in vivo of the fungicides tebuconazole and epoxiconazole. Toxicol Sci 100, 464-473.
-
(2007)
Toxicol Sci
, vol.100
, pp. 464-473
-
-
Taxvig, C.1
Hass, U.2
Axelstad, M.3
-
86
-
-
40349100229
-
Endocrine-disrupting properties in vivo of widely used azole fungicides
-
Taxvig, C., Vinggaard, A. M., Hass, U., et al. (2008). Endocrine-disrupting properties in vivo of widely used azole fungicides. Int J Androl 31, 170-177.
-
(2008)
Int J Androl
, vol.31
, pp. 170-177
-
-
Taxvig, C.1
Vinggaard, A.M.2
Hass, U.3
-
88
-
-
7544250772
-
Comparative assessment of the inhibition of recombinant human CYP19 (aromatase) by azoles used in agriculture and as drugs for humans
-
Trosken, E. R., Scholz, K., Lutz, R. W., et al. (2004). Comparative assessment of the inhibition of recombinant human CYP19 (aromatase) by azoles used in agriculture and as drugs for humans. Endocr Res 30, 387-394.
-
(2004)
Endocr Res
, vol.30
, pp. 387-394
-
-
Trosken, E.R.1
Scholz, K.2
Lutz, R.W.3
-
89
-
-
31044449968
-
Inhibition of human CYP19 by azoles used as antifungal agents and aromatase inhibitors, using a new LC-MS/MS method for the analysis of estradiol product formation
-
Trosken, E. R., Fischer, K., Volkel, W., et al. (2006). Inhibition of human CYP19 by azoles used as antifungal agents and aromatase inhibitors, using a new LC-MS/MS method for the analysis of estradiol product formation. Toxicology 219, 33-40.
-
(2006)
Toxicology
, vol.219
, pp. 33-40
-
-
Trosken, E.R.1
Fischer, K.2
Volkel, W.3
-
90
-
-
79851515789
-
Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures
-
van Dartel, D. A., Pennings, J. L., de la Fonteyne, L. J., et al. (2011). Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures. Toxicol Appl Pharmacol 251, 110-118.
-
(2011)
Toxicol Appl Pharmacol
, vol.251
, pp. 110-118
-
-
Van Dartel, D.A.1
Pennings, J.L.2
De La Fonteyne, L.J.3
-
91
-
-
34250646120
-
Comparison of fathead minnow ovary explant and H295R cell-based steroidogenesis assays for identifying endocrine-active chemicals
-
Villeneuve, D. L., Ankley, G. T., Makynen, E. A., et al. (2007). Comparison of fathead minnow ovary explant and H295R cell-based steroidogenesis assays for identifying endocrine-active chemicals. Ecotoxicol Environ Saf 68, 20-32.
-
(2007)
Ecotoxicol Environ Saf
, vol.68
, pp. 20-32
-
-
Villeneuve, D.L.1
Ankley, G.T.2
Makynen, E.A.3
-
92
-
-
0034106868
-
Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro
-
Vinggaard, A. M., Hnida, C., Breinholt, V., et al. (2000). Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro. Toxicol In Vitro 14, 227-234.
-
(2000)
Toxicol in Vitro
, vol.14
, pp. 227-234
-
-
Vinggaard, A.M.1
Hnida, C.2
Breinholt, V.3
-
93
-
-
0036773166
-
Antiandrogenic effects in vitro and in vivo of the fungicide prochloraz
-
Vinggaard, A. M., Nellemann, C., Dalgaard, M., et al. (2002). Antiandrogenic effects in vitro and in vivo of the fungicide prochloraz. Toxicol Sci 69, 344-353.
-
(2002)
Toxicol Sci
, vol.69
, pp. 344-353
-
-
Vinggaard, A.M.1
Nellemann, C.2
Dalgaard, M.3
-
94
-
-
20544470681
-
Perinatal exposure to the fungicide prochloraz feminizes the male rat offspring
-
Vinggaard, A. M., Christiansen, S., Laier, P., et al. (2005). Perinatal exposure to the fungicide prochloraz feminizes the male rat offspring. Toxicol Sci 85, 886-897.
-
(2005)
Toxicol Sci
, vol.85
, pp. 886-897
-
-
Vinggaard, A.M.1
Christiansen, S.2
Laier, P.3
-
95
-
-
43149089371
-
Screening of 397 chemicals and development of a quantitative structure - Activity relationship model for androgen receptor antagonism
-
Vinggaard, A. M., Niemela, J., Wedebye, E. B., et al. (2008). Screening of 397 chemicals and development of a quantitative structure - activity relationship model for androgen receptor antagonism. Chem Res Toxicol 21, 813-823.
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 813-823
-
-
Vinggaard, A.M.1
Niemela, J.2
Wedebye, E.B.3
-
97
-
-
77954817641
-
Predicting human developmental toxicity of pharmaceuticals using human embryonic stem cells and metabolomics
-
West, P. R., Weir, A. M., Smith, A. M., et al. (2010). Predicting human developmental toxicity of pharmaceuticals using human embryonic stem cells and metabolomics. Toxicol Appl Pharmacol 247, 18-27.
-
(2010)
Toxicol Appl Pharmacol
, vol.247
, pp. 18-27
-
-
West, P.R.1
Weir, A.M.2
Smith, A.M.3
-
98
-
-
0346366559
-
Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis
-
Wilson, V. S., Lambright, C., Furr, J., et al. (2004). Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis. Toxicol Lett 146, 207-215.
-
(2004)
Toxicol Lett
, vol.146
, pp. 207-215
-
-
Wilson, V.S.1
Lambright, C.2
Furr, J.3
|