Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals

Reproductive Toxicology

Volumn 30, Issue 4, 2010, Pages 573-582

  Kjærstad, Mia B ^a   Taxvig, Camilla ^b   Nellemann, Christine ^b   Vinggaard, Anne Marie ^b   Andersen, Helle R ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

AR reporter gene assay; Conazole antifungal; Endocrine disrupters; H295R; Imidazole; MCF 7 cell proliferation; Steroid synthesis; Triazole

Indexed keywords

ANDROGEN RECEPTOR; AROMATASE; ECONAZOLE; ENDOCRINE DISRUPTOR; EPOXICONAZOLE; ESTRADIOL; KETOCONAZOLE; MICONAZOLE; PESTICIDE; PROCHLORAZ; PROGESTERONE; PROPICONAZOLE; SULFAMETHIZOLE; TEBUCONAZOLE; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASSAY; CELL PROLIFERATION; CELL STRAIN MCF 7; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PROGESTERONE RELEASE; REPORTER GENE; TESTOSTERONE SYNTHESIS;

ANDROGEN RECEPTOR ANTAGONISTS; ANIMALS; ANTIFUNGAL AGENTS; AROMATASE; AROMATASE INHIBITORS; ARYL HYDROCARBON HYDROXYLASES; CELL LINE, TUMOR; CELL PROLIFERATION; CHO CELLS; CRICETINAE; CRICETULUS; ENDOCRINE DISRUPTORS; ESTRADIOL; ESTROGEN ANTAGONISTS; FUNGICIDES, INDUSTRIAL; GENES, REPORTER; HUMANS; IMIDAZOLES; PROGESTERONE; RECEPTORS, ANDROGEN; TESTOSTERONE; TRIAZOLES;

EID: 78649477675     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2010.07.009     Document Type: Article

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