Blockade of K+ and Ca2+ channels by azole antifungal agents in neonatal rat ventricular myocytes

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 9, 2012, Pages 1469-1475

  Sung, Dong Jun ^a   Kim, Jae Gon ^a   Won, Kyung Jong ^a   Kim, Bokyung ^a   Shin, Ho Chul ^b   Park, Jae Yong ^c   Bae, Young Min ^a  

^a Konkuk University School of Medicine   (South Korea)

^b Konkuk University   (South Korea)

^c Gyeongsang National University School of Medicine   (South Korea)

Author keywords

Arrhythmia; Azole antifungal agent; Neonate rat cardiomyocyte

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL L TYPE; DELAYED RECTIFIER POTASSIUM CHANNEL; FLUCONAZOLE; INWARDLY RECTIFYING POTASSIUM CHANNEL; ITRACONAZOLE; KETOCONAZOLE; MICONAZOLE; POTASSIUM CHANNEL; PYRROLE DERIVATIVE; ANTIFUNGAL AGENT; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; POTASSIUM; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL HERG; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEART MUSCLE CELL; IC 50; MEMBRANE CURRENT; NEWBORN; NONHUMAN; POTASSIUM CURRENT; RAT; VOLTAGE CLAMP; ACTION POTENTIAL; ANIMAL; CYTOLOGY; DRUG EFFECT; HEART VENTRICLE; METABOLISM; PATCH CLAMP; SPRAGUE DAWLEY RAT;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; ANTIFUNGAL AGENTS; AZOLES; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; ETHER-A-GO-GO POTASSIUM CHANNELS; HEART VENTRICLES; INHIBITORY CONCENTRATION 50; KETOCONAZOLE; MICONAZOLE; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84866030472     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00002     Document Type: Article

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