Oxidative stress and phthalate-induced down-regulation of steroidogenesis in MA-10 Leydig cells

Reproductive Toxicology

Volumn 42, Issue , 2013, Pages 95-101

  Zhou, Liang ^a   Beattie, Matthew C ^a   Lin, Chieh Yin ^a   Liu, June ^a   Traore, Kassim ^b   Papadopoulos, Vassilios ^c   Zirkin, Barry R ^a   Chen, Haolin ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b ELIZABETH CITY STATE UNIVERSITY   (United States)

^c RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

Leydig cell; MEHP; Oxidative stress; Phthalate; Steroidogenesis

Indexed keywords

22 HYDROXYCHOLESTEROL; BUCLADESINE; BUTHIONINE SULFOXIMINE; CHOLERA TOXIN; CHOLESTEROL; CYCLIC AMP; FORSKOLIN; GLUTATHIONE; LUTEINIZING HORMONE; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PREGNENOLONE; PROGESTERONE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CELL LEVEL; CELL STIMULATION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; HORMONE INHIBITION; LEYDIG CELL; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROGESTERONE SYNTHESIS; PROTEIN DEPLETION; REPRODUCTIVE TOXICITY; SIGNAL TRANSDUCTION; STEROIDOGENESIS;

22-HYDROXYCHOLESTEROL; 22HC; 2′,7′-DICHLORODIHYDROFLUORESCEIN DIACETATE; 3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYL TETRAZOLIUM BROMIDE; BSO; DBCAMP; DCF; DEHP; DI-(2-ETHYLHEXYL) PHTHALATE; DIBUTYRYL CAMP; GLUTATHIONE; GSH; GSΑ; IBMX; ISOBUTYL-METHYLXANTHINE; L-BUTHIONINE-SULFOXIMINE; LEYDIG CELL; LH; LUTEINIZING HORMONE; MEHP; MONO-(2-ETHYLHEXYL) PHTHALATE; MTT; OXIDATIVE STRESS; P5; PHTHALATE; PREGNENOLONE; REACTIVE OXYGEN SPECIES; ROS; STAR; STEROIDOGENESIS; STEROIDOGENIC ACUTE REGULATORY PROTEIN; STIMULATORY G PROTEIN Α SUBUNIT;

ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; CYCLIC AMP; DIETHYLHEXYL PHTHALATE; DOWN-REGULATION; GLUTATHIONE; LEYDIG CELLS; LUTEINIZING HORMONE; MALE; MICE; OXIDATIVE STRESS; PROGESTERONE; REACTIVE OXYGEN SPECIES;

EID: 84883728576     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2013.07.025     Document Type: Article

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