Tracking the role of a StAR in the sky of the new millennium

Molecular Endocrinology

Volumn 15, Issue 8, 2001, Pages 1245-1254

  Stocco, Douglas M ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; PREGNENOLONE; STEROIDOGENIC ACUTE REGULATORY PROTEIN;

CHOLESTEROL TRANSPORT; GENE MUTATION; HUMAN; LIPID TRANSPORT; MITOCHONDRIAL MEMBRANE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN STRUCTURE; REGULATORY MECHANISM; SHORT SURVEY; STEROIDOGENESIS; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION;

EID: 0034899563     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.15.8.0697     Document Type: Short Survey

References (78)

1. Preparation of anti-serum to rat cytochrome P-450 cholesterol side chain cleavage, and its use for ultrastructural localization of the immunoreactive enzyme by protein A-gold technique
2. Effect of ACTH on cholesterol side-chain cleavage in rat adrenal mitochondria
3. Evidence that the cycloheximide-sensitive site of ACTH action is in the mitochondrion
4. Intracellular movement of cholesterol in rat adrenal cells
5. Regulation of intramitochondrial cholesterol transfer to side-chain cleavage cytochrome P450scc in rat adrenal gland
6. Puromycin and adrenal responsiveness to adrenocorticotropic hormone
7. Protein synthesis and adrenocorticotropin responsiveness
8. A possible role of "steroidogenic factor" in the corticoidogenic response to ACTH; Effect of ACTH, cycloheximide and aminoglutethimide on the content of cholesterol in the outer and inner mitochondrial membrane of rat adrenal cortex
9. Regulation of the acute production of steroids in steroidogenic cells
10. A StAR search: Implications in controlling steroidogenesis
11. The steroidogenic acute regulatory (StAR) protein two years later: An update
12. The role of the steroidogenic acute regulatory protein in steroidogenesis
13. Steroidogenic acute regulatory protein. The StAR still shines brightly
14. Mitochondrial specificity of the early steps in steroidogenesis
15. Congenital lipoid adrenal hyperplasia: The human gene knockout of the steroidogenic acute regulatory protein
16. A review of the characteristics of the protein required for the acute regulation of steroid hormone biosynthesis: The case for the steroidogenic acute regulatory (StAR) protein
17. Recent advances in the role of the steroidogenic acute regulatory (StAR) protein
18. Lessons from congenital lipoid adrenal hyperplasia
19. Mitochondrial regulation of mineralocorticoid biosynthesis by calcium and the StAR protein
20. Steroidogenic acute regulatory protein
21. Regulation of steroid hormone biosynthesis: Identification of precursors of a phosphoprotein targeted to the mitochondrion in stimulated rat adrenal cortex cells
22. The 30-kDa mitochondrial proteins induced by hormone stimulation in MA-10 mouse Leydig tumor cells are processed from larger precursors
23. The purification, cloning, and expression of a novel LH-induced mitochondrial protein in MA-10 mouse Leydig tumor cells: Characterization of the steroidogenic acute regulatory protein (StAR)
24. Human steroidogenic acute regulatory protein: Functional activity in COS-1 cells, tissue-specific expression, and mapping of the gene to 8p11.2 and a pseudogene to chromosome 13
25. Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis
26. The pathophysiology and genetics of congenital lipoid adrenal hyperplasia
27. Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia
28. StAR protein and the regulation of steroid hormone biosynthesis
29. Transcriptional regulation of the StAR gene
30. Elements involved in the regulation of the StAR gene
31. Steroidogenic acute regulatory protein (StAR) and the intramitochondrial translocation of cholesterol
32. Hormonal and developmental regulation of the steroidogenic acute regulatory (StAR) protein
33. Structure of the human steroidogenic acute regulatory protein (StAR) gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase activity
34. Mechanisms of insulin-like growth factor I augmentation of follicle-stimulating hormone-induced porcine steroidogenic acute regulatory protein gene promoter activity in granulosa cells
35. Characterization of the promoter region of the mouse gene encoding the steroidogenic acute regulatory protein
36. Steroidogenic factor 1-dependent promoter activity of the human steroidogenic acute regulatory protein (StAR) gene
37. Multiple steroidogenic factor 1 binding elements in the human steroidogenic acute regulatory protein gene 5′-flanking region are required for maximal promoter activity and cyclic AMP responsiveness
38. Transcriptional regulation of the rat steroidogenic acute regulatory protein gene by steroidogenic factor 1
39. Identification of C/EBP basic region residues involved in DNA sequence recognition and half-site spacing preference
40. Luteinizing hormone-dependent gene regulation in Leydig cells may be mediated by CCAAT/enhancer-binding protein-β
41. Transcriptional regulation of the rat prostaglandin endoperoxide synthase 2 gene in granulosa cells. Evidence for the role of a cis-acting C/EBPβ promoter element
42. Interactions between SF-1 and C/EBPβ are required for high level expression from the murine StAR promoter
43. CCAAT enhancer-binding protein-β and GATA-4 binding regions within the promoter of the steroidogenic acute regulatory protein (StAR) gene are required for transcription in rat ovarian cells
44. CCAAT/enhancer-binding proteins regulate expression of the human steroidogenic acute regulatory protein (StAR) gene
45. Conditional response of the human steroidogenic acute regulatory protein gene promoter to sterol regulatory element binding protein-1a
46. Sterol regulatory element binding protein-1a regulation of the steroidogenic acute regulatory protein gene
47. A dosage sensitive locus at chromosome Xp21 is involved in male to female sex reversal
48. DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis
49. A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypoplasia congenita
50. DAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita
51. Characterization of translocation contact sites involved in the import of mitochondrial proteins
52. Protein import into mitochondria: ATP-dependent protein translocation activity in a submitochondrial fraction enriched in membrane contact sites and specific proteins
53. Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: Implications for thre mechanism of StAR action
54. The mechanism of action of steroidogenic acute regulatory protein (StAR): StAR acts on the outside of mitochondria to stimulate steroidogenesis
55. Effect of truncated forms of the steroidogenic acute regulatory protein on intramitochondrial cholesterol transfer
56. MLN64 exhibits homology with the steroidogenic acute regulatory protein (StAR) and is overexpressed in human breast carcinomas
57. MLN64 contains a domain with homology to the steroidogenic acute regulatory protein (StAR) that stimulates steroidogenesis
58. N-218 MLN64, a protein with StAR-like steroidogenic activity, is folded and cleaved similarly to StAR
59. Steroidogenic acute regulatory protein (StAR) is a sterol transfer protein
60. Regulation of mitochondrial cholesterol metabolism
61. The active form of the steroidogenic acute regulatory protein, StAR, appears to be a molten globule
62. Unveiling the mechanism of action and regulation of the steroidogenic acute regulatory protein
63. Steroidogenic acute regulatory protein and peripheral-type benzodiazepine receptor associate at the mitochondrial membrane
64. Peripheral-type benzodiazepine/diazepam binding inhibitor receptor: Biological role in steroidogenic cell function
65. START: A lipid-binding domain in StAR, HD-ZIP and signalling proteins
66. Structure and lipid transport mechanism of a StAR-related protein
67. Molten globule structure and membrane binding of the N-terminal protease-resistant domain (63-193) of the steroidogenic acute regulatory protein (StAR)
68. Electrophoretic investigations of the acid conformational change of α-lactalbumin
69. The effect of tri-N-acetylglucosamine on hydrogen exchange in hen egg white lysozyme
70. Fusion of phospholipid vesicles induced by α-lactalbmin at acidic pH
71. Penetration and fusion of phospholipid vesicles by lysozyme
72. Binding of molten globule-like conformations to lipid bilayers. Structure of native and partially folded α-lactalbumin bound to model membranes
73. Binding of StAR to synthetic membranes suggests an active molten globule
74. Membrane cholesterol dynamics: Cholesterol domains and kinetic pools
75. Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern
76. Relationship of StAR expression to mitochondrial cholesterol transfer and metabolism
77. Effects of disruption of the mitochondrial electrochemical gradient on steroidogenesis and the steroidogenic acute regulatory (StAR) protein
78. Submitochondrial localization of the steroidogenic proteins (steroidogenic acute regulatory protein, P450 side-chain cleavage and 3β-hydroxysteroid dehydrogenase isomerase enzymes) upon stimulation by intracellular calcium in adrenal glomerulosa cells