Evaluation of cytotoxicity and oxidative DNA damaging effects of di(2-ethylhexyl)-phthalate (DEHP) and mono(2-ethylhexyl)-phthalate (MEHP) on MA-10 Leydig cells and protection by selenium

Toxicology and Applied Pharmacology

Volumn 248, Issue 1, 2010, Pages 52-62

  Erkekoglu, Pinar ^a,b   Rachidi, Walid ^a   Yuzugullu, Ozge Gursoy ^c,d   Giray, Belma ^b   Favier, Alain ^a   Ozturk, Mehmet ^c,d   Hincal, Filiz ^b  

^a CEA GRENOBLE   (France)

^b HACETTEPE UNIVERSITY   (Turkey)

^c BILKENT UNIVERSITY   (Turkey)

^d UNIV GRENOBLE ALPES   (France)

Author keywords

Antioxidant enzymes; Comet assay; Cytotoxicity; Di(2 ethylhexyl) phthalate; Mono(2 ethylhexyl) phthalate; Oxidative stress; P53; Selenium

Indexed keywords

CELL DNA; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SELENOMETHIONINE; SODIUM SELENITE; ANTIOXIDANT; MONO-(2-ETHYLHEXYL)PHTHALATE;

ANIMAL CELL; ARTICLE; CELL PROTECTION; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; IMMUNOCYTOCHEMISTRY; LEYDIG CELL; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; REDOX STRESS; REPRODUCTIVE TOXICITY; ANALOGS AND DERIVATIVES; ANIMAL; COMPARATIVE STUDY; DRUG EFFECTS; MALE; METABOLISM; MUTAGEN TESTING; PATHOLOGY; TOXICITY; TUMOR CELL LINE;

ANIMALS; ANTIOXIDANTS; CELL LINE, TUMOR; COMET ASSAY; DIETHYLHEXYL PHTHALATE; DNA DAMAGE; LEYDIG CELLS; MALE; MICE; MUTAGENICITY TESTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SELENOMETHIONINE; SODIUM SELENITE; TUMOR SUPPRESSOR PROTEIN P53;

RODENTIA;

EID: 77956402478     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.07.016     Document Type: Article

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