-
1
-
-
1842530953
-
Suppression of steroidogenesis and activator protein-1 transcription factor activity in rat adrenals by vitamin E deficiency-induced oxidative stress
-
Abidi P, Leers-Sucheta S & Azhar S 2004 Suppression of steroidogenesis and activator protein-1 transcription factor activity in rat adrenals by vitamin E deficiency-induced oxidative stress. Journal of Nutritional Biochemistry 15 210-219.
-
(2004)
Journal of Nutritional Biochemistry
, vol.15
, pp. 210-219
-
-
Abidi, P.1
Leers-Sucheta, S.2
Azhar, S.3
-
2
-
-
40549101870
-
Evidence that age-related changes in p38 MAP kinase contribute to the decreased steroid production by the adrenocortical cells from old rats
-
Abidi P, Leers-Sucheta S, Cortez Y, Han J & Azhar S 2008 Evidence that age-related changes in p38 MAP kinase contribute to the decreased steroid production by the adrenocortical cells from old rats. Aging Cell 7 168-178.
-
(2008)
Aging Cell
, vol.7
, pp. 168-178
-
-
Abidi, P.1
Leers-Sucheta, S.2
Cortez, Y.3
Han, J.4
Azhar, S.5
-
3
-
-
85176693926
-
-
Alessi DR, Cuenda A, Cohen P, Dudley DT & Saltiel AR 1995 PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. Journal of Biological Chemistry 270 27489-27494.
-
Alessi DR, Cuenda A, Cohen P, Dudley DT & Saltiel AR 1995 PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. Journal of Biological Chemistry 270 27489-27494.
-
-
-
-
4
-
-
3343021042
-
Dehydroepiandrosterone and ageing. Best Practice and Research
-
Arlt W 2004 Dehydroepiandrosterone and ageing. Best Practice and Research. Clinical Endocrinology and Metabolism 18 363-380.
-
(2004)
Clinical Endocrinology and Metabolism
, vol.18
, pp. 363-380
-
-
Arlt, W.1
-
5
-
-
0029125737
-
Alteration of the adrenal antioxidant system during aging in rats
-
Azhar S, Cao L & Reaven E 1995 Alteration of the adrenal antioxidant system during aging in rats. Journal of Clinical Investigation 96 1414-1424.
-
(1995)
Journal of Clinical Investigation
, vol.96
, pp. 1414-1424
-
-
Azhar, S.1
Cao, L.2
Reaven, E.3
-
6
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of jun N-terminal kinase
-
Bennett BL, Sasaki DT, Murray BW, O'Leary EC, Sakata ST, Xu W, Leisten JC, Motiwala A, Pierce S, Satoh Y et al. 2001 SP600125, an anthrapyrazolone inhibitor of jun N-terminal kinase. PNAS 98 13681-13686.
-
(2001)
PNAS
, vol.98
, pp. 13681-13686
-
-
Bennett, B.L.1
Sasaki, D.T.2
Murray, B.W.3
O'Leary, E.C.4
Sakata, S.T.5
Xu, W.6
Leisten, J.C.7
Motiwala, A.8
Pierce, S.9
Satoh, Y.10
-
7
-
-
0018341648
-
Age-related changes in reproductive hormones and in Leydig cell responsivity in the male Fischer 344 rat
-
Bethea CL & Walker RF 1979 Age-related changes in reproductive hormones and in Leydig cell responsivity in the male Fischer 344 rat. Journal of Gerontology 34 21-27.
-
(1979)
Journal of Gerontology
, vol.34
, pp. 21-27
-
-
Bethea, C.L.1
Walker, R.F.2
-
9
-
-
1542329063
-
Aging alters the functional expression of enzymatic and non-enzymatic anti-oxidant defense system in testicular rat Leydig cells
-
Cao L, Leers-Sucheta S & Azhar S 2004 Aging alters the functional expression of enzymatic and non-enzymatic anti-oxidant defense system in testicular rat Leydig cells. Journal of Steroid Biochemistry and Molecular Biology 88 61-67.
-
(2004)
Journal of Steroid Biochemistry and Molecular Biology
, vol.88
, pp. 61-67
-
-
Cao, L.1
Leers-Sucheta, S.2
Azhar, S.3
-
10
-
-
0028558510
-
Age-related decreased Leydig cell testosterone production in the Brown Norway rat
-
Chen H, Hardy MP, Huhtaniemi L & Zirkin BR 1994 Age-related decreased Leydig cell testosterone production in the Brown Norway rat. Journal of Andrology 15 551-557.
-
(1994)
Journal of Andrology
, vol.15
, pp. 551-557
-
-
Chen, H.1
Hardy, M.P.2
Huhtaniemi, L.3
Zirkin, B.R.4
-
11
-
-
0024993001
-
Diminished adrenal steroidogenesis in aging rats: New evidence from adrenal cells cultured from young and aged normal and hypoxic animals
-
Cheng B, Horst IA, Mader SL & Kowal J 1990 Diminished adrenal steroidogenesis in aging rats: new evidence from adrenal cells cultured from young and aged normal and hypoxic animals. Molecular and Cellular Endocrinology 73 R7-R12.
-
(1990)
Molecular and Cellular Endocrinology
, vol.73
-
-
Cheng, B.1
Horst, I.A.2
Mader, S.L.3
Kowal, J.4
-
12
-
-
0035971433
-
Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity
-
Chinenov Y & Kerppola TK 2001 Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity. Oncogene 20 2438-2452.
-
(2001)
Oncogene
, vol.20
, pp. 2438-2452
-
-
Chinenov, Y.1
Kerppola, T.K.2
-
13
-
-
29444440875
-
Association of the mSin3A-histone deacetylase 1/2 corepressor complex with the mouse steroidogenic acute regulatory protein gene
-
Clem BE & Clark BJ 2006 Association of the mSin3A-histone deacetylase 1/2 corepressor complex with the mouse steroidogenic acute regulatory protein gene. Molecular Endocrinology 20 100-113.
-
(2006)
Molecular Endocrinology
, vol.20
, pp. 100-113
-
-
Clem, B.E.1
Clark, B.J.2
-
14
-
-
0028988138
-
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
-
Cueda A, Rouse J, Doza YN, Meier R, Cohen P, Gallagher TF, Young PR & Lee JC 1995 SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Letters 364 229-233.
-
(1995)
FEBS Letters
, vol.364
, pp. 229-233
-
-
Cueda, A.1
Rouse, J.2
Doza, Y.N.3
Meier, R.4
Cohen, P.5
Gallagher, T.F.6
Young, P.R.7
Lee, J.C.8
-
15
-
-
0036220150
-
Cholesterol transport, peripheral benzodiazepine receptor, and steroido-genesis in aging Leydig cells
-
Culty M, Luo L, Yao, Z-X, Chen H, Papadopoulos V & Zirkin BR 2002 Cholesterol transport, peripheral benzodiazepine receptor, and steroido-genesis in aging Leydig cells. Journal of Andrology 23 439-447.
-
(2002)
Journal of Andrology
, vol.23
, pp. 439-447
-
-
Culty, M.1
Luo, L.2
Yao, Z.-X.3
Chen, H.4
Papadopoulos, V.5
Zirkin, B.R.6
-
18
-
-
4444320809
-
MAP kinases as structural adaptors and enzymatic activators in transcription complexes
-
Edmunds JW & Mahadevan LC 2004 MAP kinases as structural adaptors and enzymatic activators in transcription complexes. Journal of Cell Science 117 3715-3723.
-
(2004)
Journal of Cell Science
, vol.117
, pp. 3715-3723
-
-
Edmunds, J.W.1
Mahadevan, L.C.2
-
19
-
-
0037036455
-
Distinct modes of cell death induced by different reactive oxygen species: Amino acyl chloramines mediate hypochlorous acid-induced apoptosis
-
Englert EP & Shacter E 2002 Distinct modes of cell death induced by different reactive oxygen species: amino acyl chloramines mediate hypochlorous acid-induced apoptosis. Journal of Biological Chemistry 277 20518-20526.
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 20518-20526
-
-
Englert, E.P.1
Shacter, E.2
-
20
-
-
0031916832
-
Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6
-
Enslen H, Raingeaud J & Davis RJ 1998 Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6. Journal of Biological Chemistry 273 1741-1748.
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 1741-1748
-
-
Enslen, H.1
Raingeaud, J.2
Davis, R.J.3
-
21
-
-
0025814980
-
Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and related aldehydes
-
Esterbauer H, Schauer RJ & Zollner H 1991 Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and related aldehydes. Free Radical Biology and Medicine 11 81-128.
-
(1991)
Free Radical Biology and Medicine
, vol.11
, pp. 81-128
-
-
Esterbauer, H.1
Schauer, R.J.2
Zollner, H.3
-
22
-
-
0017682803
-
Receptor-mediated uptake of low density hpoprotein and utilization of its cholesterol for steroid biosynthesis in cultured mouse adrenal cells
-
Faust JR, Goldstein JL & Brown MS 1977 Receptor-mediated uptake of low density hpoprotein and utilization of its cholesterol for steroid biosynthesis in cultured mouse adrenal cells. Journal of Biological Chemistry 252 4861-4871.
-
(1977)
Journal of Biological Chemistry
, vol.252
, pp. 4861-4871
-
-
Faust, J.R.1
Goldstein, J.L.2
Brown, M.S.3
-
23
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
Favata MF, Horiuchi KY, Manos EJ, Dauleriot AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitts WJ, Earl RA, Hobbs F et al. 1998 Identification of a novel inhibitor of mitogen-activated protein kinase kinase. Journal of Biological Chemistry 273 18623-18632.
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
Dauleriot, A.J.4
Stradley, D.A.5
Feeser, W.S.6
Van Dyk, D.E.7
Pitts, W.J.8
Earl, R.A.9
Hobbs, F.10
-
24
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel T & Holbrook NJ 2000 Oxidants, oxidative stress and the biology of ageing. Nature 408 239-247.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
25
-
-
33747620073
-
Cyclooxygenase-2 and prostaglandin F2 in Syrian hamster Leydig cells: Inhibitory role on luteinizing hormone/human chronic gonadotropin-stimulated testosterone production
-
Frungieri MB, Gonzalez-Calvar SI, Parborell F, Albrecht M, Mayerhofer A & Calandra RS 2006 Cyclooxygenase-2 and prostaglandin F2 in Syrian hamster Leydig cells: inhibitory role on luteinizing hormone/human chronic gonadotropin-stimulated testosterone production. Endocrinology 147 4476-4485.
-
(2006)
Endocrinology
, vol.147
, pp. 4476-4485
-
-
Frungieri, M.B.1
Gonzalez-Calvar, S.I.2
Parborell, F.3
Albrecht, M.4
Mayerhofer, A.5
Calandra, R.S.6
-
26
-
-
34247467989
-
The role of Ets transcription factors in the basal transcription of the translocator protein (18 kDa)
-
Giatzakis C, Batarseh A, Dettin L & Papadopoulos V 2007 The role of Ets transcription factors in the basal transcription of the translocator protein (18 kDa). Biochemistry 46 4763-4774.
-
(2007)
Biochemistry
, vol.46
, pp. 4763-4774
-
-
Giatzakis, C.1
Batarseh, A.2
Dettin, L.3
Papadopoulos, V.4
-
27
-
-
0031821531
-
Lipid hydroperoxide generation, turnover, and effector action in biological systems
-
Girotti AW 1998 Lipid hydroperoxide generation, turnover, and effector action in biological systems. Journal of Lipid Research 39 1529-1542.
-
(1998)
Journal of Lipid Research
, vol.39
, pp. 1529-1542
-
-
Girotti, A.W.1
-
28
-
-
0032582347
-
Interleukin-1-α induced cyclooxygenase-2 expression requires activation of both c-Jun NH2-terminal kinase and p38 MAPK signal pathways in rat renal mesangial cells
-
Guan Z, Buckman SY, Miller BW, Springer LD & Morrison AR 1998 Interleukin-1-α induced cyclooxygenase-2 expression requires activation of both c-Jun NH2-terminal kinase and p38 MAPK signal pathways in rat renal mesangial cells. Journal of Biological Chemistry 273 28670-28676.
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 28670-28676
-
-
Guan, Z.1
Buckman, S.Y.2
Miller, B.W.3
Springer, L.D.4
Morrison, A.R.5
-
29
-
-
33646701679
-
Antioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 systems in steroidogenic cells
-
Hanukoglu I 2006 Antioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 systems in steroidogenic cells. Drug Metabolism Reviews 38 171-196.
-
(2006)
Drug Metabolism Reviews
, vol.38
, pp. 171-196
-
-
Hanukoglu, I.1
-
30
-
-
20844461661
-
Testosterone in older men after the Institute of Medicine Report: Where do we go from here?
-
Harman SM 2005 Testosterone in older men after the Institute of Medicine Report: where do we go from here? Climacteric 8 124-135.
-
(2005)
Climacteric
, vol.8
, pp. 124-135
-
-
Harman, S.M.1
-
31
-
-
0346732317
-
Up-regulation of cyclooxygenase-2 and apoptosis resistance by p38 MAPK in hypericin-mediated photodynamic therapy of human cancer cells
-
Hendrickx N, Volanti C, Moens U, Seternes OM, de White P, Vandenheede JR, Pierce J & Agostinis P 2003 Up-regulation of cyclooxygenase-2 and apoptosis resistance by p38 MAPK in hypericin-mediated photodynamic therapy of human cancer cells. Journal of Biological Chemistry 278 52231-52239.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 52231-52239
-
-
Hendrickx, N.1
Volanti, C.2
Moens, U.3
Seternes, O.M.4
de White, P.5
Vandenheede, J.R.6
Pierce, J.7
Agostinis, P.8
-
33
-
-
1542666924
-
Temporal and spatial changes in transcription factor binding and histone modifications at the steroidogenic acute regulatory protein (StAR) locus associated with StAR transcription
-
Hiroi H, Christenson LK, Chang L, Sammel MD, Berger SL & Strauss JF III 2004 Temporal and spatial changes in transcription factor binding and histone modifications at the steroidogenic acute regulatory protein (StAR) locus associated with StAR transcription. Molecular Endocrinology 18 791-806.
-
(2004)
Molecular Endocrinology
, vol.18
, pp. 791-806
-
-
Hiroi, H.1
Christenson, L.K.2
Chang, L.3
Sammel, M.D.4
Berger, S.L.5
Strauss III, J.F.6
-
34
-
-
0032823313
-
Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways
-
Holtmann H, Winzen R, Holland P, Eickemeir S, Hoffmann E, Wallach D, Malinin NL, Cooper JA, Resch K & Kracht M 1999 Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways. Molecular and Cellular Biology 19 6742-6753.
-
(1999)
Molecular and Cellular Biology
, vol.19
, pp. 6742-6753
-
-
Holtmann, H.1
Winzen, R.2
Holland, P.3
Eickemeir, S.4
Hoffmann, E.5
Wallach, D.6
Malinin, N.L.7
Cooper, J.A.8
Resch, K.9
Kracht, M.10
-
35
-
-
34748824160
-
The mitogen-activated protein kinase p38 regulates activator protein 1 by direct phosphorylation of c-Jun
-
Humar M, Loop T, Schmidt R, Hoetzel A, Roesslein M, Andriopoulos N, Pahl HL, Geiger KK & Pannen BHJ 2007 The mitogen-activated protein kinase p38 regulates activator protein 1 by direct phosphorylation of c-Jun. International Journal of Biochemistry and Cell Biology 39 2278-2288.
-
(2007)
International Journal of Biochemistry and Cell Biology
, vol.39
, pp. 2278-2288
-
-
Humar, M.1
Loop, T.2
Schmidt, R.3
Hoetzel, A.4
Roesslein, M.5
Andriopoulos, N.6
Pahl, H.L.7
Geiger, K.K.8
Pannen, B.H.J.9
-
36
-
-
0030828701
-
Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38δ
-
Jiang Y, Gram H, Zhao M, New L, Gu J, Feng L, Di Padova F, Ulevitch RJ & Han J 1997 Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38δ. Journal of Biological Chemistry 272 30122-30128.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 30122-30128
-
-
Jiang, Y.1
Gram, H.2
Zhao, M.3
New, L.4
Gu, J.5
Feng, L.6
Di Padova, F.7
Ulevitch, R.J.8
Han, J.9
-
37
-
-
0032756960
-
Oxalate-induced changes in the viability and growth of human renal epithelial cells
-
Jonassen JA, Cooney R, Kennington L, Gravel K, Honeyman T & Scheid CR 1999 Oxalate-induced changes in the viability and growth of human renal epithelial cells. Journal of the American Society of Nephrology 14 S446-S451.
-
(1999)
Journal of the American Society of Nephrology
, vol.14
-
-
Jonassen, J.A.1
Cooney, R.2
Kennington, L.3
Gravel, K.4
Honeyman, T.5
Scheid, C.R.6
-
38
-
-
26444515048
-
The decline of androgen levels in elderly men and its clinical and therapeutic implications
-
Kaufman JM & Vermeulen A 2005 The decline of androgen levels in elderly men and its clinical and therapeutic implications. Endocrine Reviews 26 833-876.
-
(2005)
Endocrine Reviews
, vol.26
, pp. 833-876
-
-
Kaufman, J.M.1
Vermeulen, A.2
-
39
-
-
0034648298
-
The Haber-Weiss reaction and mechanisms of toxicity
-
Kehrer JP 2000 The Haber-Weiss reaction and mechanisms of toxicity. Toxicology 149 43-50.
-
(2000)
Toxicology
, vol.149
, pp. 43-50
-
-
Kehrer, J.P.1
-
40
-
-
11044223897
-
Analysis of dichlorodihydrofluorescein and dihydrocalcein as probes for the detection of intracellular reactive oxygen species
-
Keller A, Mohamed A, Dröse S, Brandt U, Fleming I & Brandes RP 2004 Analysis of dichlorodihydrofluorescein and dihydrocalcein as probes for the detection of intracellular reactive oxygen species. Free Radical Research 38 1257-1267.
-
(2004)
Free Radical Research
, vol.38
, pp. 1257-1267
-
-
Keller, A.1
Mohamed, A.2
Dröse, S.3
Brandt, U.4
Fleming, I.5
Brandes, R.P.6
-
41
-
-
0842291584
-
High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation
-
Kelley L, Allan G & Azhar S 2004 High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation. Endocrinology 145 548-555.
-
(2004)
Endocrinology
, vol.145
, pp. 548-555
-
-
Kelley, L.1
Allan, G.2
Azhar, S.3
-
42
-
-
0141755317
-
Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: Potential role in diabetic nephropathy
-
Kiritoshi S, Nishikawa T, Sonoda K, Kukidome D, Senokuchi T, Matsuo T, Matsumura T, Tokunaga H, Brownlee M & Araki E 2003 Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy. Diabetes 52 2570-2577.
-
(2003)
Diabetes
, vol.52
, pp. 2570-2577
-
-
Kiritoshi, S.1
Nishikawa, T.2
Sonoda, K.3
Kukidome, D.4
Senokuchi, T.5
Matsuo, T.6
Matsumura, T.7
Tokunaga, H.8
Brownlee, M.9
Araki, E.10
-
44
-
-
9144219652
-
A lipid peroxidation-derived inflammatory mediator: Identifiaction of 4-hydroxy-2-nonenal as a potential inducer of cyclooxygenase-2 in macrophages
-
Kumgai T, Matsukawa N, Kaneko Y, Kusumi Y, Mitsumata M & Uchida K 2004 A lipid peroxidation-derived inflammatory mediator: identifiaction of 4-hydroxy-2-nonenal as a potential inducer of cyclooxygenase-2 in macrophages. Journal of Biological Chemistry 279 48389-48396.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 48389-48396
-
-
Kumgai, T.1
Matsukawa, N.2
Kaneko, Y.3
Kusumi, Y.4
Mitsumata, M.5
Uchida, K.6
-
45
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis JM & Avruch J 2001 Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiological Reviews 81 807-869.
-
(2001)
Physiological Reviews
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
46
-
-
0034077529
-
Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade
-
Lasa M, Mahtani KR, Finch A, Brewer G, Saklatvala J & Clark AR 2000 Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade. Molecular and Cellular Biology 20 4265-4274.
-
(2000)
Molecular and Cellular Biology
, vol.20
, pp. 4265-4274
-
-
Lasa, M.1
Mahtani, K.R.2
Finch, A.3
Brewer, G.4
Saklatvala, J.5
Clark, A.R.6
-
47
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, McNulty D, Blumenthal MJ, Heys JR, Landvatter SW et al. 1994 A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372 739-746.
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
-
48
-
-
0033105616
-
Down-regulation of steroidogenic acute regulatory (StAR) protein in rat Leydig cells: Implications for regulation of testosterone production during aging
-
Leers-Sucheta S, Stocco DM & Azhar S 1999 Down-regulation of steroidogenic acute regulatory (StAR) protein in rat Leydig cells: implications for regulation of testosterone production during aging. Mechanisms of Ageing and Development 107 197-203.
-
(1999)
Mechanisms of Ageing and Development
, vol.107
, pp. 197-203
-
-
Leers-Sucheta, S.1
Stocco, D.M.2
Azhar, S.3
-
50
-
-
0027275205
-
Age-related decline in the steroidogenic capacity of isolated rat Rat Leydig cells: A defect in cholesterol mobilization and processing
-
Liao C, Reaven E & Azhar S 1993 Age-related decline in the steroidogenic capacity of isolated rat Rat Leydig cells: a defect in cholesterol mobilization and processing. Journal of Steroid Biochemistry and Molecular Biology 64 39-47.
-
(1993)
Journal of Steroid Biochemistry and Molecular Biology
, vol.64
, pp. 39-47
-
-
Liao, C.1
Reaven, E.2
Azhar, S.3
-
51
-
-
0042889456
-
PAP7, a PBR/ PKA-RIα-associated protein: A new element in the relay of the hormonal induction of steroidogenesis
-
Liu J, Li H & Padadopoulos V 2003 PAP7, a PBR/ PKA-RIα-associated protein: a new element in the relay of the hormonal induction of steroidogenesis. Journal of Steroid Biochemistry and Molecular Biology 85 275-283.
-
(2003)
Journal of Steroid Biochemistry and Molecular Biology
, vol.85
, pp. 275-283
-
-
Liu, J.1
Li, H.2
Padadopoulos, V.3
-
52
-
-
0035189247
-
Leydig cell aging: Steroidogenic acute regulatory protein (StAR) and cholesterol side-chain cleavage enzyme
-
Luo L, Chen H & Zirkin BR 2001 Leydig cell aging: steroidogenic acute regulatory protein (StAR) and cholesterol side-chain cleavage enzyme. Journal of Andrology 22 149-156.
-
(2001)
Journal of Andrology
, vol.22
, pp. 149-156
-
-
Luo, L.1
Chen, H.2
Zirkin, B.R.3
-
53
-
-
0020580974
-
Aging of the rat adrenocortical cell: Response to ACTH and cyclic AMP in vitro
-
Malamed S & Carsia RV 1983 Aging of the rat adrenocortical cell: response to ACTH and cyclic AMP in vitro. Journal of Gerontology 38 130-136.
-
(1983)
Journal of Gerontology
, vol.38
, pp. 130-136
-
-
Malamed, S.1
Carsia, R.V.2
-
54
-
-
15444380459
-
Regulation of steroidogenic acute regulatory protein expression: Functional and physiological consequences
-
Manna PR & Stocco DM 2005 Regulation of steroidogenic acute regulatory protein expression: functional and physiological consequences. Current Drug Targets. Immune, Endocrine and Metabolic Disorders 5 93-108.
-
(2005)
Current Drug Targets. Immune, Endocrine and Metabolic Disorders
, vol.5
, pp. 93-108
-
-
Manna, P.R.1
Stocco, D.M.2
-
55
-
-
35748951940
-
Crosstalk of CREB and Fos/Jun on a single cis-element: Transcriptional repression of the steroidogenic acute regulatory protein gene
-
Manna PR & Stocco DM 2007 Crosstalk of CREB and Fos/Jun on a single cis-element: transcriptional repression of the steroidogenic acute regulatory protein gene. Journal of Molecular Endocrinology 39 261-277.
-
(2007)
Journal of Molecular Endocrinology
, vol.39
, pp. 261-277
-
-
Manna, P.R.1
Stocco, D.M.2
-
56
-
-
0344825081
-
Involvement of multiple transcription factors in the regulation of steroidogenic acute regulatory protein gene expression
-
Manna PR, Wand XJ & Stocco DM 2003 Involvement of multiple transcription factors in the regulation of steroidogenic acute regulatory protein gene expression. Steroids 68 1125-1134.
-
(2003)
Steroids
, vol.68
, pp. 1125-1134
-
-
Manna, P.R.1
Wand, X.J.2
Stocco, D.M.3
-
57
-
-
1542357572
-
Assessment of the role of activator protein-1 on transcription of the mouse steroidogenic acute regulatory protein gene
-
Manna PR, Eubank DW & Stocco DM 2004 Assessment of the role of activator protein-1 on transcription of the mouse steroidogenic acute regulatory protein gene. Molecular Endocrinology 18 558-573.
-
(2004)
Molecular Endocrinology
, vol.18
, pp. 558-573
-
-
Manna, P.R.1
Eubank, D.W.2
Stocco, D.M.3
-
58
-
-
0018178434
-
A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples
-
Markwell MA, Hass SM, Bieber L & Tolbert NE 1978 A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Analytical Biochemistry 87 206-210.
-
(1978)
Analytical Biochemistry
, vol.87
, pp. 206-210
-
-
Markwell, M.A.1
Hass, S.M.2
Bieber, L.3
Tolbert, N.E.4
-
59
-
-
0036260697
-
Cellular response to oxidative stress: Signaling for suicide and survival
-
Martindale JL & Holbrook NJ 2002 Cellular response to oxidative stress: signaling for suicide and survival. Journal of Cellular Physiology 192 1-15.
-
(2002)
Journal of Cellular Physiology
, vol.192
, pp. 1-15
-
-
Martindale, J.L.1
Holbrook, N.J.2
-
60
-
-
14044265068
-
Stress-responsive protein kinases in redox-regulated apoptosis signaling
-
Matsuzawa A & Ichijo H 2005 Stress-responsive protein kinases in redox-regulated apoptosis signaling. Antioxidants and Redox Signaling 7 472-481.
-
(2005)
Antioxidants and Redox Signaling
, vol.7
, pp. 472-481
-
-
Matsuzawa, A.1
Ichijo, H.2
-
62
-
-
0035009632
-
Impaired activation of AP-1 and altered expression of constitutive proteins in rat adrenal during aging
-
Medicherla R, Leers-Sucheta S, Luto Y & Azhar S 2001 Impaired activation of AP-1 and altered expression of constitutive proteins in rat adrenal during aging. Mechanisms of Ageing and Development 122 1169-1186.
-
(2001)
Mechanisms of Ageing and Development
, vol.122
, pp. 1169-1186
-
-
Medicherla, R.1
Leers-Sucheta, S.2
Luto, Y.3
Azhar, S.4
-
64
-
-
33847235315
-
StAR search - what we know about how the steroidogenic acute regulatory protein mediates mitochondrial cholesterol import
-
Miller WL 2007 StAR search - what we know about how the steroidogenic acute regulatory protein mediates mitochondrial cholesterol import. Molecular Endocrinology 21 589-601.
-
(2007)
Molecular Endocrinology
, vol.21
, pp. 589-601
-
-
Miller, W.L.1
-
65
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T 1983 Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods 65 55-63.
-
(1983)
Journal of Immunological Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
66
-
-
3042591342
-
Early single cell bifurcation of pro- and antiapoptotic states during oxidative stress
-
Nair VD, Yuen T, Olanow CW & Sealfon SC 2004 Early single cell bifurcation of pro- and antiapoptotic states during oxidative stress. Journal of Biological Chemistry 279 27494-27501.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 27494-27501
-
-
Nair, V.D.1
Yuen, T.2
Olanow, C.W.3
Sealfon, S.C.4
-
67
-
-
0034804050
-
Reactive oxygen species up-regulates cyclooxygenase-2, p53, and Bax mRNA expression in bovine luteal cells
-
Nakamura T & Sakamoto K 2001 Reactive oxygen species up-regulates cyclooxygenase-2, p53, and Bax mRNA expression in bovine luteal cells. Biochemical and Biophysical Research Communications 284 203-210.
-
(2001)
Biochemical and Biophysical Research Communications
, vol.284
, pp. 203-210
-
-
Nakamura, T.1
Sakamoto, K.2
-
68
-
-
33746035655
-
Translocator protein (18 kDa): New nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function
-
Papadopoulos V, Baraldi M, Guilarte TR, Knudsen TB, Lacapè J-J, Lindemann P, Norenberg MD, Nutt D, Weizman A, Zhang M-R et al. 2006 Translocator protein (18 kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function. Trends in Pharmacological Sciences 27 402-409.
-
(2006)
Trends in Pharmacological Sciences
, vol.27
, pp. 402-409
-
-
Papadopoulos, V.1
Baraldi, M.2
Guilarte, T.R.3
Knudsen, T.B.4
Lacapè, J.-J.5
Lindemann, P.6
Norenberg, M.D.7
Nutt, D.8
Weizman, A.9
Zhang, M.-R.10
-
69
-
-
33847039156
-
Is there a mitochondrial signaling complex facilitating cholesterol import?
-
Papadopoulos V, Liu J & Culty M 2007 Is there a mitochondrial signaling complex facilitating cholesterol import? Molecular and Cellular Endocrinology 265-266 69-64.
-
(2007)
Molecular and Cellular Endocrinology
, vol.265-266
, pp. 69-64
-
-
Papadopoulos, V.1
Liu, J.2
Culty, M.3
-
70
-
-
0035980171
-
Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes
-
Pimental DR, Amin JK, Xiao L, Miller T, Viereck J, Oliver-krasinski J, Baliga R, Wang J, Siwik DA, Singh K et al. 2001 Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes. Circulation Research 89 453-460.
-
(2001)
Circulation Research
, vol.89
, pp. 453-460
-
-
Pimental, D.R.1
Amin, J.K.2
Xiao, L.3
Miller, T.4
Viereck, J.5
Oliver-krasinski, J.6
Baliga, R.7
Wang, J.8
Siwik, D.A.9
Singh, K.10
-
71
-
-
0023269864
-
Effects of aging on cholesterol content and cholesterol-metabolizing enzymes in the rat adrenal gland
-
Popplewell PY & Azhar S 1987 Effects of aging on cholesterol content and cholesterol-metabolizing enzymes in the rat adrenal gland. Endocrinology 121 64-73.
-
(1987)
Endocrinology
, vol.121
, pp. 64-73
-
-
Popplewell, P.Y.1
Azhar, S.2
-
72
-
-
0023026808
-
Differential effects of aging on adrenocorticotropin receptors, adenosine 3′5′-monophosphate response, and corticosterone secretion in adrenocortical cells from Sprague-Dawley rats
-
Popplewell PY, Tsubokawa M, Ramachandran J & Azhar S 1986 Differential effects of aging on adrenocorticotropin receptors, adenosine 3′5′-monophosphate response, and corticosterone secretion in adrenocortical cells from Sprague-Dawley rats. Endocrinology 119 2206-2213.
-
(1986)
Endocrinology
, vol.119
, pp. 2206-2213
-
-
Popplewell, P.Y.1
Tsubokawa, M.2
Ramachandran, J.3
Azhar, S.4
-
73
-
-
0038363324
-
p38 Isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun: The determinant role of the isoforms in the MAPK signal specificity
-
Pramanik R, Qi X, Borowicz S, Choubey D, Schultz RM, Han J & Chen G 2003 p38 Isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun: the determinant role of the isoforms in the MAPK signal specificity. Journal of Biological Chemistry 278 4831-4839.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 4831-4839
-
-
Pramanik, R.1
Qi, X.2
Borowicz, S.3
Choubey, D.4
Schultz, R.M.5
Han, J.6
Chen, G.7
-
74
-
-
0018749073
-
Mutations in cyclic AMP-dependent protein kinase and corticotrophin (ACTH)-sensitive adenylate cyclase effect adrenal steroidogenesis
-
Rae PA, Gutmann NS, Tsao J & Schimmer BP 1979 Mutations in cyclic AMP-dependent protein kinase and corticotrophin (ACTH)-sensitive adenylate cyclase effect adrenal steroidogenesis. PNAS 76 1896-1900.
-
(1979)
PNAS
, vol.76
, pp. 1896-1900
-
-
Rae, P.A.1
Gutmann, N.S.2
Tsao, J.3
Schimmer, B.P.4
-
75
-
-
0030051528
-
MKK3- and MKK-6 regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
-
Raingeaud J, Whitmarsh AJ, Barrett T, Dérijard B & Davis RJ 1996 MKK3- and MKK-6 regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Molecular and Cellular Biology 16 1247-1255.
-
(1996)
Molecular and Cellular Biology
, vol.16
, pp. 1247-1255
-
-
Raingeaud, J.1
Whitmarsh, A.J.2
Barrett, T.3
Dérijard, B.4
Davis, R.J.5
-
76
-
-
34248597065
-
Differential regulation and properties of MAPKs
-
Raman M, Chen W & Cobb MH 2007 Differential regulation and properties of MAPKs. Oncogene 26 3100-3112.
-
(2007)
Oncogene
, vol.26
, pp. 3100-3112
-
-
Raman, M.1
Chen, W.2
Cobb, M.H.3
-
77
-
-
0025187223
-
Interaction of lipoproteins with isolated ovary plasma membranes
-
Reaven E, Shi X-Y & Azhar S 1990 Interaction of lipoproteins with isolated ovary plasma membranes. Journal of Biological Chemistry 265 19100-19111.
-
(1990)
Journal of Biological Chemistry
, vol.265
, pp. 19100-19111
-
-
Reaven, E.1
Shi, X.-Y.2
Azhar, S.3
-
80
-
-
0034717943
-
Intramitochondrial cholesterol transfer
-
Stocco DM 2000 Intramitochondrial cholesterol transfer. Biochimica et Biophysica Acta 1486 184-197.
-
(2000)
Biochimica et Biophysica Acta
, vol.1486
, pp. 184-197
-
-
Stocco, D.M.1
-
81
-
-
0030047248
-
Regulation of the acute production of steroids in steroidogenic cells
-
Stucco DM & Clark BJ 1996 Regulation of the acute production of steroids in steroidogenic cells. Endocrine Reviews 17 221-244.
-
(1996)
Endocrine Reviews
, vol.17
, pp. 221-244
-
-
Stucco, D.M.1
Clark, B.J.2
-
82
-
-
21444439970
-
Phosphorylation of c-Fos by Members of the p38 MAPK family: Role in the AP-1 response to UV light
-
Tanos T, Marinissen MJ, Leskow FC, Hochbaum D, Martinetto H, Gutkind JS & Coso OA 2005 Phosphorylation of c-Fos by Members of the p38 MAPK family: role in the AP-1 response to UV light. Journal of Biological Chemistry 280 18842-18852.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 18842-18852
-
-
Tanos, T.1
Marinissen, M.J.2
Leskow, F.C.3
Hochbaum, D.4
Martinetto, H.5
Gutkind, J.S.6
Coso, O.A.7
-
83
-
-
0031459459
-
Scavenger receptor calss B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells
-
Temel RE, Trigatti B, DeMattos RB, Azhar S, Krieger M & Williams DL 1997 Scavenger receptor calss B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells. PNAS 94 13600-13605.
-
(1997)
PNAS
, vol.94
, pp. 13600-13605
-
-
Temel, R.E.1
Trigatti, B.2
DeMattos, R.B.3
Azhar, S.4
Krieger, M.5
Williams, D.L.6
-
84
-
-
0001618646
-
Determination of cholesterol and cholesterol esters
-
Tercyak A 1991 Determination of cholesterol and cholesterol esters. Journal of Nutritional Biochemistry 2 281-292.
-
(1991)
Journal of Nutritional Biochemistry
, vol.2
, pp. 281-292
-
-
Tercyak, A.1
-
86
-
-
0018607928
-
Age-related alterations of isolated rat Leydig cell function: Gonadotropin receptors, adenosine 3′5′-monophosphate response, and testosterone secretion
-
Tsitouras PD, Kowatch MA & Harman SM 1979 Age-related alterations of isolated rat Leydig cell function: gonadotropin receptors, adenosine 3′5′-monophosphate response, and testosterone secretion. Endocrinology 105 1400-1405.
-
(1979)
Endocrinology
, vol.105
, pp. 1400-1405
-
-
Tsitouras, P.D.1
Kowatch, M.A.2
Harman, S.M.3
-
87
-
-
0034466444
-
Cellular response to bioactive lipid peroxidation products
-
Uchida K 2000 Cellular response to bioactive lipid peroxidation products. Free Radical Research 33 731-737.
-
(2000)
Free Radical Research
, vol.33
, pp. 731-737
-
-
Uchida, K.1
-
88
-
-
0033593225
-
Activation of stress signaling pathways by the end product of lipid peroxidation: 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production
-
Uchida K, Shiraishi M, Naito Y, Torii Y, Nakamura Y & Osawa T 1999 Activation of stress signaling pathways by the end product of lipid peroxidation: 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production. Journal of Biological Chemistry 274 2234-2242.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 2234-2242
-
-
Uchida, K.1
Shiraishi, M.2
Naito, Y.3
Torii, Y.4
Nakamura, Y.5
Osawa, T.6
-
89
-
-
1042289790
-
Cellular carbonyl stress enhances the expression of plasminogen activator inhibitor-1 in rat white adipocytes via reactive oxygen species-dependent pathway
-
Uchida Y, Ohba K, Yoshioka T, Irie K, Muraki T & Maru Y 2004 Cellular carbonyl stress enhances the expression of plasminogen activator inhibitor-1 in rat white adipocytes via reactive oxygen species-dependent pathway. Journal of Biological Chemistry 279 4075-4083.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 4075-4083
-
-
Uchida, Y.1
Ohba, K.2
Yoshioka, T.3
Irie, K.4
Muraki, T.5
Maru, Y.6
-
90
-
-
20444390632
-
The decline in testosterone biosynthesis during male aging: A consequence of multiple alterations
-
Wang X & Stocco DM 2005 The decline in testosterone biosynthesis during male aging: a consequence of multiple alterations. Molecular and Cellular Endocrinology 238 1-7.
-
(2005)
Molecular and Cellular Endocrinology
, vol.238
, pp. 1-7
-
-
Wang, X.1
Stocco, D.M.2
-
91
-
-
0042315391
-
Inhibition of cyclooxygenase-2 activity enhances steroidogenesis and steroidogenic acute regulatory gene expression in MA-10 mouse Leydig cells
-
Wang X, Dyson MT, Jo Y & Stocco DM 2003 Inhibition of cyclooxygenase-2 activity enhances steroidogenesis and steroidogenic acute regulatory gene expression in MA-10 mouse Leydig cells. Endocrinology 144 3368-3375.
-
(2003)
Endocrinology
, vol.144
, pp. 3368-3375
-
-
Wang, X.1
Dyson, M.T.2
Jo, Y.3
Stocco, D.M.4
-
93
-
-
34547196977
-
Regulation of gene transcription by mitogen-activated protein kinase signaling pathways
-
Whitmarsh AJ 2007 Regulation of gene transcription by mitogen-activated protein kinase signaling pathways. Biochimica et Biophysica Acta 1773 1285-1298.
-
(2007)
Biochimica et Biophysica Acta
, vol.1773
, pp. 1285-1298
-
-
Whitmarsh, A.J.1
-
94
-
-
0029808748
-
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
-
Whitmarsh AJ & Davis RJ 1996 Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. Journal of Molecular Medicine 74 589-607.
-
(1996)
Journal of Molecular Medicine
, vol.74
, pp. 589-607
-
-
Whitmarsh, A.J.1
Davis, R.J.2
-
95
-
-
0032928614
-
Mitogen-activated protein kinase: Conservation ofa three-kinase module from yeast to human
-
Widmann C, Gibson S, Jarpe MB & Johnson GL 1999 Mitogen-activated protein kinase: conservation ofa three-kinase module from yeast to human. Physiological Reviews 79 143-180.
-
(1999)
Physiological Reviews
, vol.79
, pp. 143-180
-
-
Widmann, C.1
Gibson, S.2
Jarpe, M.B.3
Johnson, G.L.4
-
96
-
-
27144524287
-
Hypertonic induction of COX-2 in collecting duct cells by reactive oxygen species of mitochondrial origin
-
Yang T, Zhang A, Honeggar M, Kohn DE, Mizel D, Sanders K, Hoidal JR, Briggs JP & Schnermann JB 2005 Hypertonic induction of COX-2 in collecting duct cells by reactive oxygen species of mitochondrial origin. Journal of Biological Chemistry 280 34966-34973.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 34966-34973
-
-
Yang, T.1
Zhang, A.2
Honeggar, M.3
Kohn, D.E.4
Mizel, D.5
Sanders, K.6
Hoidal, J.R.7
Briggs, J.P.8
Schnermann, J.B.9
-
97
-
-
33746108825
-
Nitric oxide stimulates COX-2 expression in cultured collecting duct cells through MAP kinases and superoxide but not cGMP
-
Yang T, Zhang A, pasumarthy A, Zhang L, Warnock Z & Schnermann JB 2006 Nitric oxide stimulates COX-2 expression in cultured collecting duct cells through MAP kinases and superoxide but not cGMP. American Journal of Physiology. Renal Physiology 291 F891-F895.
-
(2006)
American Journal of Physiology. Renal Physiology
, vol.291
-
-
Yang, T.1
Zhang, A.2
pasumarthy, A.3
Zhang, L.4
Warnock, Z.5
Schnermann, J.B.6
-
98
-
-
34248598495
-
The lipid peroxidation end-product 4-HNE induces COX-2 expression through p38 MAPK activation in 3T3-L1 adipose cell
-
Zarrouki B, Soares AF, Guichardant M, Lagarde M & Géloën A 2007 The lipid peroxidation end-product 4-HNE induces COX-2 expression through p38 MAPK activation in 3T3-L1 adipose cell. FEBS Letters 581 2394-2400.
-
(2007)
FEBS Letters
, vol.581
, pp. 2394-2400
-
-
Zarrouki, B.1
Soares, A.F.2
Guichardant, M.3
Lagarde, M.4
Géloën, A.5
-
99
-
-
13844255631
-
Novel signaling stimulated by arsenite increases cholesterol metabolism through increases in unphosphorylated acute regulatory (StAR) protein
-
Zhao D, Xue H, Artemenko I & Jefcoate C 2006 Novel signaling stimulated by arsenite increases cholesterol metabolism through increases in unphosphorylated acute regulatory (StAR) protein. Molecular and Cellular Endocrinology 231 95-107.
-
(2006)
Molecular and Cellular Endocrinology
, vol.231
, pp. 95-107
-
-
Zhao, D.1
Xue, H.2
Artemenko, I.3
Jefcoate, C.4
-
100
-
-
0033796721
-
Regulation of Leydig cell steroidogenic function during aging
-
Zirkin BR & Chen H 2000 Regulation of Leydig cell steroidogenic function during aging. Biology of Reproduction 63 977-981.
-
(2000)
Biology of Reproduction
, vol.63
, pp. 977-981
-
-
Zirkin, B.R.1
Chen, H.2
|