Effects of di-(2-ethylhexyl) phthalate and four of its metabolites on steroidogenesis in MA-10 cells

Ecotoxicology and Environmental Safety

Volumn 79, Issue , 2012, Pages 108-115

  Piché, Carlie D ^a   Sauvageau, Dominic ^a,b   Vanlian, Marie ^a   Erythropel, Hanno C ^a   Robaire, Bernard ^a   Leask, Richard L ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

DEHP metabolites; Di (2 ethylhexyl) phthalate; MA 10 cells; Phthalate; Plasticizer; Steroidogenesis

Indexed keywords

2 ETHYLHEXANAL; 2 ETHYLHEXANOIC ACID; 2 ETHYLHEXANOL; CARRIER PROTEIN; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); HEXANAL; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PLASTICIZER; PROGESTERONE; STEROIDOGENIC ACUTE REGULATORY PROTEIN; UNCLASSIFIED DRUG;

ENZYME ACTIVITY; EXPERIMENTAL STUDY; GENE EXPRESSION; METABOLITE; PHTHALATE; POLLUTION EFFECT; STEROID; TOXICITY;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYP11A1 GENE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE EXPRESSION PROFILING; IN VITRO STUDY; LEYDIG CELL; MALE; MOUSE; NONHUMAN; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCTIVE TOXICITY; STAR GENE; STEROIDOGENESIS; TESTIS TOXICITY; TSPO GENE;

ALDEHYDES; ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; DIETHYLHEXYL PHTHALATE; ENDOCRINE DISRUPTORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEXANOIC ACIDS; HEXANOLS; LEYDIG CELL TUMOR; MALE; MICE; PLASTICIZERS; REAL-TIME POLYMERASE CHAIN REACTION; STEROIDS;

ANIMALIA;

EID: 84858285868     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2011.12.008     Document Type: Article

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