-
1
-
-
67650927396
-
Epistatic interactions modulate the evolution of mammalian mitochondrial respiratory complex components
-
doi:10.1186/1471-2164-10-266
-
Azevedo, L., Carneiro, J., van Asch, B., Moleirinho, A., Pereira, F., and Amorim, A. (2009). Epistatic interactions modulate the evolution of mammalian mitochondrial respiratory complex components. BMC Genomics 10:266. doi:10.1186/1471-2164-10-266
-
(2009)
BMC Genomics
, vol.10
, pp. 266
-
-
Azevedo, L.1
Carneiro, J.2
van Asch, B.3
Moleirinho, A.4
Pereira, F.5
Amorim, A.6
-
2
-
-
0742305866
-
Network biology: understanding the cell's functional organization
-
Barabasi, A. L., and Oltvai, Z. N. (2004). Network biology: understanding the cell's functional organization. Nat. Rev. Genet. 5, 101-113.
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 101-113
-
-
Barabasi, A.L.1
Oltvai, Z.N.2
-
4
-
-
83255187278
-
A systematic eQTL study of cis-trans epistasis in 210 HapMap individuals
-
Becker, J., Wendland, J. R., Haenisch, B., Nothen, M. M., and Schumacher, J. (2012). A systematic eQTL study of cis-trans epistasis in 210 HapMap individuals. Eur. J. Hum. Genet. 20, 97-101.
-
(2012)
Eur. J. Hum. Genet.
, vol.20
, pp. 97-101
-
-
Becker, J.1
Wendland, J.R.2
Haenisch, B.3
Nothen, M.M.4
Schumacher, J.5
-
5
-
-
34249041230
-
Exploring genetic interactions and networks with yeast
-
Boone, C., Bussey, H., and Andrews, B. J. (2007). Exploring genetic interactions and networks with yeast. Nat. Rev. Genet. 8, 437-449.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 437-449
-
-
Boone, C.1
Bussey, H.2
Andrews, B.J.3
-
6
-
-
0035478854
-
Random forests
-
Breiman, L. (2001). Random forests. Mach. Learn. 45, 5-32.
-
(2001)
Mach. Learn.
, vol.45
, pp. 5-32
-
-
Breiman, L.1
-
7
-
-
55449096399
-
Genetical genomics: spotlight on QTL hotspots
-
doi:10.1371/journal.pgen.1000232
-
Breitling, R., Li, Y., Tesson, B. M., Fu, J., Wu, C., Wiltshire, T., et al. (2008). Genetical genomics: spotlight on QTL hotspots. PLoS Genet. 4:e1000232. doi:10.1371/journal.pgen.1000232
-
(2008)
PLoS Genet.
, vol.4
-
-
Breitling, R.1
Li, Y.2
Tesson, B.M.3
Fu, J.4
Wu, C.5
Wiltshire, T.6
-
8
-
-
23644434284
-
Genetic interactions between polymorphisms that affect gene expression in yeast
-
Brem, R. B., Storey, J. D., Whittle, J., and Kruglyak, L. (2005). Genetic interactions between polymorphisms that affect gene expression in yeast. Nature 436, 701-703.
-
(2005)
Nature
, vol.436
, pp. 701-703
-
-
Brem, R.B.1
Storey, J.D.2
Whittle, J.3
Kruglyak, L.4
-
9
-
-
0037177625
-
Genetic dissection of transcriptional regulation in budding yeast
-
Brem, R. B., Yvert, G., Clinton, R., and Kruglyak, L. (2002). Genetic dissection of transcriptional regulation in budding yeast. Science 296, 752-755.
-
(2002)
Science
, vol.296
, pp. 752-755
-
-
Brem, R.B.1
Yvert, G.2
Clinton, R.3
Kruglyak, L.4
-
10
-
-
37649007447
-
A forest-based approach to identifying gene and gene gene interactions
-
U.S.A.
-
Chen, X., Liu, C. T., Zhang, M., and Zhang, H. (2007). A forest-based approach to identifying gene and gene gene interactions. Proc. Natl. Acad. Sci. U.S.A. 104, 19199-19203.
-
(2007)
Proc. Natl. Acad. Sci.
, vol.104
, pp. 19199-19203
-
-
Chen, X.1
Liu, C.T.2
Zhang, M.3
Zhang, H.4
-
11
-
-
60349092402
-
Mapping complex disease traits with global gene expression
-
Cookson, W., Liang, L., Abecasis, G., Moffatt, M., and Lathrop, M. (2009). Mapping complex disease traits with global gene expression. Nat. Rev. Genet. 10, 184-194.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 184-194
-
-
Cookson, W.1
Liang, L.2
Abecasis, G.3
Moffatt, M.4
Lathrop, M.5
-
12
-
-
0036797562
-
Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans
-
Cordell, H. J. (2002). Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans. Hum. Mol. Genet. 11, 2463-2468.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2463-2468
-
-
Cordell, H.J.1
-
13
-
-
80855127462
-
The causes of epistasis
-
de Visser, J. A., Cooper, T. F., and Elena, S. F. (2011). The causes of epistasis. Proc. Biol. Sci. 278, 3617-3624.
-
(2011)
Proc. Biol. Sci.
, vol.278
, pp. 3617-3624
-
-
de Visser, J.A.1
Cooper, T.F.2
Elena, S.F.3
-
14
-
-
0032441150
-
Cluster analysis and display of genome-wide expression patterns
-
U.S.A.
-
Eisen M.B. Spellman, P. T., Brown, P. O., and Botstein, D. (1998). Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. U.S.A. 95, 14863-14868.
-
(1998)
Proc. Natl. Acad. Sci.
, vol.95
, pp. 14863-14868
-
-
Eisen, M.B.1
Spellman, P.T.2
Brown, P.O.3
Botstein, D.4
-
15
-
-
70349629971
-
Using biological networks to search for interacting loci in genome-wide association studies
-
Emily, M., Mailund, T., Hein, J., Schauser, L., and Schierup, M. H. (2009). Using biological networks to search for interacting loci in genome-wide association studies. Eur. J. Hum. Genet. 17, 1231-1240.
-
(2009)
Eur. J. Hum. Genet.
, vol.17
, pp. 1231-1240
-
-
Emily, M.1
Mailund, T.2
Hein, J.3
Schauser, L.4
Schierup, M.H.5
-
16
-
-
33749388527
-
Two-stage two-locus models in genome-wide association
-
doi:10.1371/journal.pgen.0020157
-
Evans, D. M., Marchini, J., Morris, A. P., and Cardon, L. R. (2006). Two-stage two-locus models in genome-wide association. PLoS Genet. 2:e157. doi:10.1371/journal.pgen.0020157
-
(2006)
PLoS Genet.
, vol.2
-
-
Evans, D.M.1
Marchini, J.2
Morris, A.P.3
Cardon, L.R.4
-
17
-
-
84971185409
-
The correlation between relatives on the supposition of mendelian inheritance
-
Fisher, R. A. (1918). The correlation between relatives on the supposition of mendelian inheritance. Trans R Soc Edinb. 52, 399-433.
-
(1918)
Trans R Soc Edinb.
, vol.52
, pp. 399-433
-
-
Fisher, R.A.1
-
18
-
-
54749157466
-
Regulatory hotspots in the malaria parasite genome dictate transcriptional variation
-
doi:10.1371/journal.pbio.0060238
-
Gonzales, J. M., Patel, J. J., Ponmee, N., Jiang, L., Tan, A., Maher, S. P., et al. (2008). Regulatory hotspots in the malaria parasite genome dictate transcriptional variation. PLoS Biol. 6:e238. doi:10.1371/journal.pbio.0060238
-
(2008)
PLoS Biol.
, vol.6
-
-
Gonzales, J.M.1
Patel, J.J.2
Ponmee, N.3
Jiang, L.4
Tan, A.5
Maher, S.P.6
-
19
-
-
67349242369
-
Interactions in epidemiology: relevance, identification, and estimation
-
Greenland, S. (2009). Interactions in epidemiology: relevance, identification, and estimation. Epidemiology 20, 14-17.
-
(2009)
Epidemiology
, vol.20
, pp. 14-17
-
-
Greenland, S.1
-
20
-
-
0036898532
-
Rapid coevolution of the nematode sex-determining genes fem-3 and tra-2
-
Haag, E. S., Wang, S., and Kimble, J. (2002). Rapid coevolution of the nematode sex-determining genes fem-3 and tra-2. Curr. Biol. 12, 2035-2041.
-
(2002)
Curr. Biol.
, vol.12
, pp. 2035-2041
-
-
Haag, E.S.1
Wang, S.2
Kimble, J.3
-
21
-
-
79960867202
-
bNEAT: a Bayesian network method for detecting epistatic interactions in genome-wide association studies
-
doi:10.1186/1471-2164-12-S2-S9
-
Han, B., and Chen, X. W. (2011). bNEAT: a Bayesian network method for detecting epistatic interactions in genome-wide association studies. BMC Genomics 12(Suppl. 2):S9. doi:10.1186/1471-2164-12-S2-S9
-
(2011)
BMC Genomics
, vol.12
, Issue.SUPPL. 2
-
-
Han, B.1
Chen, X.W.2
-
22
-
-
74249100674
-
Genome-wide association data reveal a global map of genetic interactions among protein complexes
-
doi:10.1371/journal.pgen.1000782
-
Hannum, G., Srivas, R., Guenole, A., van Attikum, H., Krogan, N. J., Karp, R. M., et al. (2009). Genome-wide association data reveal a global map of genetic interactions among protein complexes. PLoS Genet. 5:e1000782. doi:10.1371/journal.pgen.1000782
-
(2009)
PLoS Genet.
, vol.5
-
-
Hannum, G.1
Srivas, R.2
Guenole, A.3
van Attikum, H.4
Krogan, N.J.5
Karp, R.M.6
-
23
-
-
33644770200
-
Negative epistasis between natural variants of the Saccharomyces cerevisiae MLH1 and PMS1 genes results in a defect in mismatch repair
-
U.S.A.
-
Heck, J. A., Argueso, J. L., Gemici, Z., Reeves, R. G., Bernard, A., Aquadro, C. F., et al. (2006). Negative epistasis between natural variants of the Saccharomyces cerevisiae MLH1 and PMS1 genes results in a defect in mismatch repair. Proc. Natl. Acad. Sci. U.S.A. 103, 3256-3261.
-
(2006)
Proc. Natl. Acad. Sci.
, vol.103
, pp. 3256-3261
-
-
Heck, J.A.1
Argueso, J.L.2
Gemici, Z.3
Reeves, R.G.4
Bernard, A.5
Aquadro, C.F.6
-
24
-
-
75849134020
-
INTERSNP: genome-wide interaction analysis guided by a priori information
-
Herold, C., Steffens, M., Brockschmidt, F. F., Baur, M. P., and Becker, T. (2009). INTERSNP: genome-wide interaction analysis guided by a priori information. Bioinformatics 25, 3275-3281.
-
(2009)
Bioinformatics
, vol.25
, pp. 3275-3281
-
-
Herold, C.1
Steffens, M.2
Brockschmidt, F.F.3
Baur, M.P.4
Becker, T.5
-
25
-
-
80052590363
-
Characterizing genetic interactions in human disease association studies using statistical epistasis networks
-
doi:10.1186/1471-2105-12-364
-
Hu, T., Sinnott-Armstrong, N. A., Kiralis, J. W., Andrew, A. S., Karagas, M. R., and Moore, J. H. (2011). Characterizing genetic interactions in human disease association studies using statistical epistasis networks. BMC Bioinformatics 12:364. doi:10.1186/1471-2105-12-364
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 364
-
-
Hu, T.1
Sinnott-Armstrong, N.A.2
Kiralis, J.W.3
Andrew, A.S.4
Karagas, M.R.5
Moore, J.H.6
-
26
-
-
84859812487
-
Symmetric epistasis estimation (SEE) and its application to dissecting interaction map of Plasmodium falciparum
-
Huang, Y., Siwo, G., Wuchty, S., Ferdig, M. T., and Przytycka, T. M. (2012). Symmetric epistasis estimation (SEE) and its application to dissecting interaction map of Plasmodium falciparum. Mol. Biosyst. 8, 1544-1552.
-
(2012)
Mol. Biosyst.
, vol.8
, pp. 1544-1552
-
-
Huang, Y.1
Siwo, G.2
Wuchty, S.3
Ferdig, M.T.4
Przytycka, T.M.5
-
27
-
-
39749132326
-
Genotype matrix mapping: searching for quantitative trait loci interactions in genetic variation in complex traits
-
Isobe, S., Nakaya, A., and Tabata, S. (2007). Genotype matrix mapping: searching for quantitative trait loci interactions in genetic variation in complex traits. DNA Res. 14, 217-225.
-
(2007)
DNA Res.
, vol.14
, pp. 217-225
-
-
Isobe, S.1
Nakaya, A.2
Tabata, S.3
-
28
-
-
0001002693
-
Simulation of quantitative characters from qualitatively acting genes
-
Jana, S. (1971). Simulation of quantitative characters from qualitatively acting genes. Theor. Appl. Genet. 41, 216-226.
-
(1971)
Theor. Appl. Genet.
, vol.41
, pp. 216-226
-
-
Jana, S.1
-
29
-
-
60849093174
-
A random forest approach to the detection of epistatic interactions in case-control studies
-
doi:10.1186/1471-2105-10-S1-S65
-
Jiang, R., Tang, W., Wu, X., and Fu, W. (2009). A random forest approach to the detection of epistatic interactions in case-control studies. BMC Bioinformatics 10(Suppl. 1), S65. doi:10.1186/1471-2105-10-S1-S65
-
(2009)
BMC Bioinformatics
, vol.10
, Issue.SUPPL 1
-
-
Jiang, R.1
Tang, W.2
Wu, X.3
Fu, W.4
-
30
-
-
84964922459
-
A fast algorithm for learning epistatic genomic relationships
-
Jiang, X., Neapolitan, R. E., Barmada, M. M., Visweswaran, S., and Cooper, G. F. (2010). A fast algorithm for learning epistatic genomic relationships. AMIA Annu. Symp. Proc. 2010, 341-345.
-
(2010)
AMIA Annu. Symp. Proc.
, vol.2010
, pp. 341-345
-
-
Jiang, X.1
Neapolitan, R.E.2
Barmada, M.M.3
Visweswaran, S.4
Cooper, G.F.5
-
31
-
-
15044353444
-
Transcription control reprogramming in genetic backup circuits
-
Kafri, R., Bar-Even, A., and Pilpel, Y. (2005). Transcription control reprogramming in genetic backup circuits. Nat. Genet. 37, 295-299.
-
(2005)
Nat. Genet.
, vol.37
, pp. 295-299
-
-
Kafri, R.1
Bar-Even, A.2
Pilpel, Y.3
-
32
-
-
84866358654
-
Integration of disease-specific single nucleotide polymorphisms, expression quantitative trait loci and coexpression networks reveal novel candidate genes for type 2 diabetes
-
Kang, H. P., Yang, X., Chen, R., Zhang, B., Corona, E., Schadt, E. E., et al. (2012). Integration of disease-specific single nucleotide polymorphisms, expression quantitative trait loci and coexpression networks reveal novel candidate genes for type 2 diabetes. Diabetologia. 55, 2205-2213.
-
(2012)
Diabetologia.
, vol.55
, pp. 2205-2213
-
-
Kang, H.P.1
Yang, X.2
Chen, R.3
Zhang, B.4
Corona, E.5
Schadt, E.E.6
-
33
-
-
83655198250
-
Comparison of strategies to detect epistasis from eQTL data
-
doi:10.1371/journal.pone.0028415
-
Kapur, K., Schupbach, T., Xenarios, I., Kutalik, Z., and Bergmann, S. (2011). Comparison of strategies to detect epistasis from eQTL data. PLoS ONE 6, e28415. doi:10.1371/journal.pone.0028415
-
(2011)
PLoS ONE
, vol.6
-
-
Kapur, K.1
Schupbach, T.2
Xenarios, I.3
Kutalik, Z.4
Bergmann, S.5
-
34
-
-
22844450110
-
Systematic interpretation of genetic interactions using protein networks
-
Kelley, R., and Ideker, T. (2005). Systematic interpretation of genetic interactions using protein networks. Nat. Biotechnol. 23, 561-566.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 561-566
-
-
Kelley, R.1
Ideker, T.2
-
35
-
-
79953645463
-
Identifying causal genes and dysregulated pathways in complex diseases
-
doi:10.1371/journal.pcbi.1001095
-
Kim, Y. A., Wuchty, S., and Przytycka, T. M. (2011). Identifying causal genes and dysregulated pathways in complex diseases. PLoS Comput. Biol. 7, e1001095. doi:10.1371/journal.pcbi.1001095
-
(2011)
PLoS Comput. Biol.
, vol.7
-
-
Kim, Y.A.1
Wuchty, S.2
Przytycka, T.M.3
-
36
-
-
80052731734
-
Epistatic selection between coding and regulatory variation in human evolution and disease
-
Lappalainen, T., Montgomery, S. B., Nica, A. C., and Dermitzakis, E. T. (2011). Epistatic selection between coding and regulatory variation in human evolution and disease. Am. J. Hum. Genet. 89, 459-463.
-
(2011)
Am. J. Hum. Genet.
, vol.89
, pp. 459-463
-
-
Lappalainen, T.1
Montgomery, S.B.2
Nica, A.C.3
Dermitzakis, E.T.4
-
37
-
-
79959708547
-
From SNPs to genes: disease association at the gene level
-
doi:10.1371/journal.pone.0020133
-
Lehne, B., Lewis, C. M., and Schlitt, T. (2011). From SNPs to genes: disease association at the gene level. PLoS ONE 6,e20133. doi:10.1371/journal.pone.0020133
-
(2011)
PLoS ONE
, vol.6
-
-
Lehne, B.1
Lewis, C.M.2
Schlitt, T.3
-
38
-
-
79960642108
-
Molecular mechanisms of epistasis within and between genes
-
Lehner, B. (2011). Molecular mechanisms of epistasis within and between genes. Trends Genet. 27, 323-331.
-
(2011)
Trends Genet.
, vol.27
, pp. 323-331
-
-
Lehner, B.1
-
39
-
-
66149119826
-
Modularity and interactions in the genetics of gene expression
-
U.S.A.
-
Litvin, O., Causton, H. C., Chen, B. J., and Pe'er, D. (2009). Modularity and interactions in the genetics of gene expression. Proc. Natl. Acad. Sci. U.S.A. 106, 6441-6446.
-
(2009)
Proc. Natl. Acad. Sci.
, vol.106
, pp. 6441-6446
-
-
Litvin, O.1
Causton, H.C.2
Chen, B.J.3
Pe'er, D.4
-
40
-
-
79953753220
-
Genome-wide interaction-based association analysis identified multiple new susceptibility loci for common diseases
-
doi:10.1371/journal.pgen.1001338
-
Liu, Y., Xu, H., Chen, S., Chen, X., Zhang, Z., Zhu, Z., et al. (2011). Genome-wide interaction-based association analysis identified multiple new susceptibility loci for common diseases. PLoS Genet. 7, e1001338. doi:10.1371/journal.pgen.1001338
-
(2011)
PLoS Genet.
, vol.7
-
-
Liu, Y.1
Xu, H.2
Chen, S.3
Chen, X.4
Zhang, Z.5
Zhu, Z.6
-
41
-
-
42149137884
-
Defining genetic interaction
-
U.S.A.
-
Mani, R., St Onge, R. P., Hartman, J. L. IV., Giaever, G., and Roth, F. P. (2008). Defining genetic interaction. Proc. Natl. Acad. Sci. U.S.A. 105, 3461-3466.
-
(2008)
Proc. Natl. Acad. Sci.
, vol.105
, pp. 3461-3466
-
-
Mani, R.1
St Onge, R.P.2
Hartman, J.L.3
Giaever, G.4
Roth, F.P.5
-
42
-
-
16844366786
-
Genome-wide strategies for detecting multiple loci that influence complex diseases
-
Marchini, J., Donnelly, P., and Cardon, L. R. (2005). Genome-wide strategies for detecting multiple loci that influence complex diseases. Nat. Genet. 37, 413-417.
-
(2005)
Nat. Genet.
, vol.37
, pp. 413-417
-
-
Marchini, J.1
Donnelly, P.2
Cardon, L.R.3
-
43
-
-
63449100294
-
Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis
-
doi:10.1371/journal.pgen.1000432
-
McKinney, B. A., Crowe, J. E., Guo, J., and Tian, D. (2009). Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis. PLoS Genet. 5, e1000432. doi:10.1371/journal.pgen.1000432
-
(2009)
PLoS Genet.
, vol.5
-
-
McKinney, B.A.1
Crowe, J.E.2
Guo, J.3
Tian, D.4
-
44
-
-
34548577158
-
Evaporative cooling feature selection for genotypic data involving interactions
-
McKinney, B. A., Reif, D. M., White, B. C., Crowe, J. E. Jr., and Moore, J. H. (2007). Evaporative cooling feature selection for genotypic data involving interactions. Bioinformatics 23, 2113-2120.
-
(2007)
Bioinformatics
, vol.23
, pp. 2113-2120
-
-
McKinney, B.A.1
Reif, D.M.2
White, B.C.3
Crowe Jr., J.E.4
Moore, J.H.5
-
45
-
-
70349885499
-
An algorithm for learning maximum entropy probability models of disease risk that efficiently searches and sparingly encodes multilocus genomic interactions
-
Miller, D. J., Zhang, Y., Yu, G., Liu, Y., Chen, L., Langefeld, C. D., et al. (2009). An algorithm for learning maximum entropy probability models of disease risk that efficiently searches and sparingly encodes multilocus genomic interactions. Bioinformatics 25, 2478-2485.
-
(2009)
Bioinformatics
, vol.25
, pp. 2478-2485
-
-
Miller, D.J.1
Zhang, Y.2
Yu, G.3
Liu, Y.4
Chen, L.5
Langefeld, C.D.6
-
46
-
-
46949101742
-
Exploiting the proteome to improve the genome-wide genetic analysis of epistasis in common human diseases
-
Pattin, K. A., and Moore, J. H. (2008). Exploiting the proteome to improve the genome-wide genetic analysis of epistasis in common human diseases. Hum. Genet. 124, 19-29.
-
(2008)
Hum. Genet.
, vol.124
, pp. 19-29
-
-
Pattin, K.A.1
Moore, J.H.2
-
47
-
-
79960931252
-
Replication and explorations of high-order epistasis using a large advanced intercross line pedigree
-
doi:10.1371/journal.pgen.1002180
-
Pettersson, M., Besnier, F., Siegel, P. B., and Carlborg, O. (2011). Replication and explorations of high-order epistasis using a large advanced intercross line pedigree. PLoS Genet. 7, e1002180. doi:10.1371/journal.pgen.1002180
-
(2011)
PLoS Genet.
, vol.7
-
-
Pettersson, M.1
Besnier, F.2
Siegel, P.B.3
Carlborg, O.4
-
48
-
-
54149088214
-
Epistasis - the essential role of gene interactions in the structure and evolution of genetic systems
-
Phillips, P. C. (2008). Epistasis - the essential role of gene interactions in the structure and evolution of genetic systems. Nat. Rev. Genet. 9, 855-867.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 855-867
-
-
Phillips, P.C.1
-
49
-
-
0035154941
-
Marker pair selection for mapping quantitative trait loci
-
Piepho, H. P., and Gauch, H. G. Jr. (2001). Marker pair selection for mapping quantitative trait loci. Genetics 157, 433-444.
-
(2001)
Genetics
, vol.157
, pp. 433-444
-
-
Piepho, H.P.1
Gauch, H.G.Jr.2
-
50
-
-
0034973569
-
Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer
-
Ritchie, M. D., Hahn, L. W., Roodi, N., Bailey, L. R., Dupont, W. D., Parl, F. F., et al. (2001). Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am. J. Hum. Genet. 69, 138-147.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 138-147
-
-
Ritchie, M.D.1
Hahn, L.W.2
Roodi, N.3
Bailey, L.R.4
Dupont, W.D.5
Parl, F.F.6
-
51
-
-
70249134919
-
Molecular networks as sensors and drivers of common human diseases
-
Schadt, E. E. (2009). Molecular networks as sensors and drivers of common human diseases. Nature 461, 218-223.
-
(2009)
Nature
, vol.461
, pp. 218-223
-
-
Schadt, E.E.1
-
52
-
-
83455201603
-
Performance analysis of novel methods for detecting epistasis
-
doi:10.1186/1471-2105-12-475
-
Shang, J., Zhang, J., Sun, Y., Liu, D., Ye, D., and Yin, Y. (2011). Performance analysis of novel methods for detecting epistasis. BMC Bioinformatics 12, 475. doi:10.1186/1471-2105-12-475
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 475
-
-
Shang, J.1
Zhang, J.2
Sun, Y.3
Liu, D.4
Ye, D.5
Yin, Y.6
-
53
-
-
34548570371
-
Power to detect higher-order epistatic interactions in a metabolic pathway using a new mapping strategy
-
Stich, B., Yu, J., Melchinger, A. E., Piepho, H. P., Utz, H. F., Maurer, H. P., et al. (2007). Power to detect higher-order epistatic interactions in a metabolic pathway using a new mapping strategy. Genetics 176, 563-570.
-
(2007)
Genetics
, vol.176
, pp. 563-570
-
-
Stich, B.1
Yu, J.2
Melchinger, A.E.3
Piepho, H.P.4
Utz, H.F.5
Maurer, H.P.6
-
54
-
-
23644434473
-
Multiple locus linkage analysis of genomewide expression in yeast
-
doi:10.1371/journal.pbio.0030267
-
Storey, J. D., Akey, J. M., and Kruglyak, L. (2005). Multiple locus linkage analysis of genomewide expression in yeast. PLoS Biol. 3, e267. doi:10.1371/journal.pbio.0030267
-
(2005)
PLoS Biol.
, vol.3
-
-
Storey, J.D.1
Akey, J.M.2
Kruglyak, L.3
-
55
-
-
34548738566
-
Population genomics of human gene expression
-
Stranger, B. E., Nica, A. C., Forrest, M. S., Dimas, A., Bird, C. P., Beazley, C., et al. (2007). Population genomics of human gene expression. Nat. Genet. 39, 1217-1224.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1217-1224
-
-
Stranger, B.E.1
Nica, A.C.2
Forrest, M.S.3
Dimas, A.4
Bird, C.P.5
Beazley, C.6
-
56
-
-
0141993704
-
A gene-coexpression network for global discovery of conserved genetic modules
-
Stuart, J. M., Segal, E., Koller, D., and Kim, S. K. (2003). A gene-coexpression network for global discovery of conserved genetic modules. Science 302, 249-255.
-
(2003)
Science
, vol.302
, pp. 249-255
-
-
Stuart, J.M.1
Segal, E.2
Koller, D.3
Kim, S.K.4
-
57
-
-
42949096140
-
eQED: an efficient method for interpreting eQTL associations using protein networks
-
Suthram, S., Beyer, A., Karp, R. M., Eldar, Y., and Ideker, T. (2008). eQED: an efficient method for interpreting eQTL associations using protein networks. Mol. Syst. Biol. 4, 162.
-
(2008)
Mol. Syst. Biol.
, vol.4
, pp. 162
-
-
Suthram, S.1
Beyer, A.2
Karp, R.M.3
Eldar, Y.4
Ideker, T.5
-
58
-
-
78651324347
-
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
-
Szklarczyk, D., Franceschini, A., Kuhn, M., Simonovic, M., Roth, A., Minguez, P., et al. (2011). The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. Nucleic Acids Res. 39, D561-D568.
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Szklarczyk, D.1
Franceschini, A.2
Kuhn, M.3
Simonovic, M.4
Roth, A.5
Minguez, P.6
-
59
-
-
66649108315
-
Epistatic module detection for case-control studies: a Bayesian model with a Gibbs sampling strategy
-
doi:10.1371/journal.pgen.1000464
-
Tang, W., Wu, X., Jiang, R., and Li, Y. (2009). Epistatic module detection for case-control studies: a Bayesian model with a Gibbs sampling strategy. PLoS Genet. 5, e1000464. doi:10.1371/journal.pgen.1000464
-
(2009)
PLoS Genet.
, vol.5
-
-
Tang, W.1
Wu, X.2
Jiang, R.3
Li, Y.4
-
60
-
-
0025959790
-
Effect modification and the limits of biological inference from epidemiologic data
-
Thompson, W. D. (1991). Effect modification and the limits of biological inference from epidemiologic data. J. Clin. Epidemiol. 44, 221-232.
-
(1991)
J. Clin. Epidemiol.
, vol.44
, pp. 221-232
-
-
Thompson, W.D.1
-
61
-
-
84855661466
-
Travelling the world of gene-gene interactions
-
Van Steen, K. (2012). Travelling the world of gene-gene interactions. Brief. Bioinformatics 13, 1-19.
-
(2012)
Brief. Bioinformatics
, vol.13
, pp. 1-19
-
-
Van Steen, K.1
-
62
-
-
78649938122
-
Functional overlap and regulatory links shape genetic interactions between signaling pathways
-
van Wageningen, S., Kemmeren, P., Lijnzaad, P., Margaritis, T., Benschop, J. J., de Castro, I. J., et al. (2010). Functional overlap and regulatory links shape genetic interactions between signaling pathways. Cell 143, 991-1004.
-
(2010)
Cell
, vol.143
, pp. 991-1004
-
-
van Wageningen, S.1
Kemmeren, P.2
Lijnzaad, P.3
Margaritis, T.4
Benschop, J.J.5
de Castro, I.J.6
-
63
-
-
0035452110
-
Alternative definitions of epistasis: dependence and interaction
-
Wade, M. J., Winther, R. G., Agrawal, A. F., and Goodnight, C. J. (2001). Alternative definitions of epistasis: dependence and interaction. Trends Ecol. Evol. (Amst.) 16, 498-504.
-
(2001)
Trends Ecol. Evol. (Amst.)
, vol.16
, pp. 498-504
-
-
Wade, M.J.1
Winther, R.G.2
Agrawal, A.F.3
Goodnight, C.J.4
-
64
-
-
36248936497
-
The road to modularity
-
Wagner, G. P., Pavlicev, M., and Cheverud, J. M. (2007). The road to modularity. Nat. Rev. Genet. 8, 921-931.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 921-931
-
-
Wagner, G.P.1
Pavlicev, M.2
Cheverud, J.M.3
-
65
-
-
77956395423
-
BOOST: a fast approach to detecting gene-gene interactions in genome-wide case-control studies
-
Wan, X., Yang, C., Yang, Q., Xue, H., Fan, X., Tang, N. L., et al. (2010a). BOOST: a fast approach to detecting gene-gene interactions in genome-wide case-control studies. Am. J. Hum. Genet. 87, 325-340.
-
(2010)
Am. J. Hum. Genet.
, vol.87
, pp. 325-340
-
-
Wan, X.1
Yang, C.2
Yang, Q.3
Xue, H.4
Fan, X.5
Tang, N.L.6
-
66
-
-
75249087515
-
Predictive rule inference for epistatic interaction detection in genome-wide association studies
-
Wan, X., Yang, C., Yang, Q., Xue, H., Tang, N. L., and Yu, W. (2010b). Predictive rule inference for epistatic interaction detection in genome-wide association studies. Bioinformatics 26, 30-37.
-
(2010)
Bioinformatics
, vol.26
, pp. 30-37
-
-
Wan, X.1
Yang, C.2
Yang, Q.3
Xue, H.4
Tang, N.L.5
Yu, W.6
-
67
-
-
60849086187
-
MegaSNPHunter: a learning approach to detect disease predisposition SNPs and high level interactions in genome wide association study
-
doi:10.1186/1471-2105-10-13
-
Wan, X., Yang, C., Yang, Q., Xue, H., Tang, N. L., and Yu, W. (2009). MegaSNPHunter: a learning approach to detect disease predisposition SNPs and high level interactions in genome wide association study. BMC Bioinformatics 10,13. doi:10.1186/1471-2105-10-13
-
(2009)
BMC Bioinformatics
, vol.10
, pp. 13
-
-
Wan, X.1
Yang, C.2
Yang, Q.3
Xue, H.4
Tang, N.L.5
Yu, W.6
-
68
-
-
79951521125
-
A model selection approach for expression quantitative trait loci (eQTL) mapping
-
Wang, P., Dawson, J. A., Keller, M. P., Yandell, B. S., Thornberry, N. A., Zhang, B. B., et al. (2011a). A model selection approach for expression quantitative trait loci (eQTL) mapping. Genetics 187, 611-621.
-
(2011)
Genetics
, vol.187
, pp. 611-621
-
-
Wang, P.1
Dawson, J.A.2
Keller, M.P.3
Yandell, B.S.4
Thornberry, N.A.5
Zhang, B.B.6
-
69
-
-
78650304195
-
Statistical interaction in human genetics: how should we model it if we are looking for biological interaction?
-
Wang, X., Elston, R. C., and Zhu, X. (2011b). Statistical interaction in human genetics: how should we model it if we are looking for biological interaction? Nat. Rev. Genet. 12, 74.
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 74
-
-
Wang, X.1
Elston, R.C.2
Zhu, X.3
-
70
-
-
77953271464
-
AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm
-
doi:10.1186/1756-0500-3-117
-
Wang, Y., Liu, X., Robbins, K., and Rekaya, R. (2010). AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm. BMC Res. Notes 3, 117. doi:10.1186/1756-0500-3-117
-
(2010)
BMC Res. Notes
, vol.3
, pp. 117
-
-
Wang, Y.1
Liu, X.2
Robbins, K.3
Rekaya, R.4
-
71
-
-
77950075619
-
Controlling false positives in the mapping of epistatic QTL
-
Wei, W. H., Knott, S., Haley, C. S., and de Koning, D. J. (2010). Controlling false positives in the mapping of epistatic QTL. Heredity 104, 401-409.
-
(2010)
Heredity
, vol.104
, pp. 401-409
-
-
Wei, W.H.1
Knott, S.2
Haley, C.S.3
de Koning, D.J.4
-
72
-
-
60149109479
-
SNPHarvester: a filtering-based approach for detecting epistatic interactions in genome-wide association studies
-
Yang, C., He, Z., Wan, X., Yang, Q., Xue, H., and Yu, W. (2009). SNPHarvester: a filtering-based approach for detecting epistatic interactions in genome-wide association studies. Bioinformatics 25, 504-511.
-
(2009)
Bioinformatics
, vol.25
, pp. 504-511
-
-
Yang, C.1
He, Z.2
Wan, X.3
Yang, Q.4
Xue, H.5
Yu, W.6
-
73
-
-
75149156212
-
Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
-
doi:10.1186/1471-2105-11-S1-S18
-
Yang, C., Wan, X., Yang, Q., Xue, H., and Yu, W. (2010). Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso. BMC Bioinformatics 11(Suppl. 1), S18. doi:10.1186/1471-2105-11-S1-S18
-
(2010)
BMC Bioinformatics
, vol.11
, Issue.SUPPL. 1
-
-
Yang, C.1
Wan, X.2
Yang, Q.3
Xue, H.4
Yu, W.5
-
74
-
-
34547830821
-
Mapping the genetic architecture of complex traits in experimental populations
-
Yang, J., Zhu, J., and Williams, R. W. (2007). Mapping the genetic architecture of complex traits in experimental populations. Bioinformatics 23, 1527-1536.
-
(2007)
Bioinformatics
, vol.23
, pp. 1527-1536
-
-
Yang, J.1
Zhu, J.2
Williams, R.W.3
-
75
-
-
83155178509
-
SNPInterForest: a new method for detecting epistatic interactions
-
doi:10.1186/1471-2105-12-469
-
Yoshida, M., and Koike, A. (2011). SNPInterForest: a new method for detecting epistatic interactions. BMC Bioinformatics 12, 469. doi:10.1186/1471-2105-12-469
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 469
-
-
Yoshida, M.1
Koike, A.2
-
76
-
-
76749132132
-
A Bayesian partition method for detecting pleiotropic and epistatic eQTL modules
-
doi:10.1371/journal.pcbi.1000642
-
Zhang, W., Zhu, J., Schadt, E. E., and Liu, J. S. (2010a). A Bayesian partition method for detecting pleiotropic and epistatic eQTL modules. PLoS Comput. Biol. 6, e1000642. doi:10.1371/journal.pcbi.1000642
-
(2010)
PLoS Comput. Biol.
, vol.6
-
-
Zhang, W.1
Zhu, J.2
Schadt, E.E.3
Liu, J.S.4
-
77
-
-
77954182718
-
TEAM: efficient two-locus epistasis tests in human genome-wide association study
-
Zhang, X., Huang, S., Zou, F., and Wang, W. (2010b). TEAM: efficient two-locus epistasis tests in human genome-wide association study. Bioinformatics 26, i217-227.
-
(2010)
Bioinformatics
, vol.26
-
-
Zhang, X.1
Huang, S.2
Zou, F.3
Wang, W.4
-
78
-
-
77950798630
-
COE: a general approach for efficient genome-wide two-locus epistasis test in disease association study
-
Zhang, X., Pan, F., Xie, Y., Zou, F., and Wang, W. (2010c). COE: a general approach for efficient genome-wide two-locus epistasis test in disease association study. J. Comput. Biol. 17, 401-415.
-
(2010)
J. Comput. Biol.
, vol.17
, pp. 401-415
-
-
Zhang, X.1
Pan, F.2
Xie, Y.3
Zou, F.4
Wang, W.5
-
80
-
-
61949439681
-
FastChi: an efficient algorithm for analyzing gene-gene interactions
-
Zhang, X., Zou, F., and Wang, W. (2009). FastChi: an efficient algorithm for analyzing gene-gene interactions. Pac. Symp. Biocomput. 2009, 528-539.
-
(2009)
Pac. Symp. Biocomput.
, vol.2009
, pp. 528-539
-
-
Zhang, X.1
Zou, F.2
Wang, W.3
-
81
-
-
34548352849
-
Bayesian inference of epistatic interactions in case-control studies
-
Zhang, Y., and Liu, J. S. (2007). Bayesian inference of epistatic interactions in case-control studies. Nat. Genet. 39, 1167-1173.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1167-1173
-
-
Zhang, Y.1
Liu, J.S.2
-
82
-
-
70350105765
-
Multiple interval mapping for gene expression QTL analysis
-
Zou, W., and Zeng, Z. B. (2009). Multiple interval mapping for gene expression QTL analysis. Genetica 137, 125-134.
-
(2009)
Genetica
, vol.137
, pp. 125-134
-
-
Zou, W.1
Zeng, Z.B.2
-
83
-
-
84856405512
-
The mystery of missing heritability: genetic interactions create phantom heritability
-
U.S.A.
-
Zuk, O., Hechter, E., Sunyaev, S. R., and Lander, E. S. (2012). The mystery of missing heritability: genetic interactions create phantom heritability. Proc. Natl. Acad. Sci. U.S.A. 109, 1193-1198.
-
(2012)
Proc. Natl. Acad. Sci.
, vol.109
, pp. 1193-1198
-
-
Zuk, O.1
Hechter, E.2
Sunyaev, S.R.3
Lander, E.S.4
|