-
1
-
-
84969213492
-
Genomewide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Consortium WTCC
-
Consortium WTCC (2007) Genomewide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447:661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
2
-
-
0037177625
-
Genetic dissection of transcriptional regulation in budding yeast
-
Brem RB, Yvert G, Clinton R, Kruglyak L (2002) Genetic dissection of transcriptional regulation in budding yeast. Science 296:752-755.
-
(2002)
Science
, vol.296
, pp. 752-755
-
-
Brem, R.B.1
Yvert, G.2
Clinton, R.3
Kruglyak, L.4
-
3
-
-
0037370311
-
Natural variation in human gene expression assessed in lymphoblastoid cells
-
Cheung VG, et al. (2003) Natural variation in human gene expression assessed in lymphoblastoid cells. Nat Genet 33:422-425.
-
(2003)
Nat Genet
, vol.33
, pp. 422-425
-
-
Cheung, V.G.1
-
4
-
-
0037456823
-
Genetics of gene expression surveyed in maize, mouse, and man
-
Schadt EE, et al. (2003) Genetics of gene expression surveyed in maize, mouse, and man. Nature 422:297-302.
-
(2003)
Nature
, vol.422
, pp. 297-302
-
-
Schadt, E.E.1
-
5
-
-
0042856391
-
Trans -acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors
-
Yvert G, et al. (2003) Trans -acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors. Nat Genet 35:57-64.
-
(2003)
Nat Genet
, vol.35
, pp. 57-64
-
-
Yvert, G.1
-
6
-
-
13444306165
-
The landscape of genetic complexity across 5,700 gene expression traits in yeast
-
Brem RB, Kruglyak L (2005) The landscape of genetic complexity across 5,700 gene expression traits in yeast. Proc Natl Acad Sci USA 102:1572-1577.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1572-1577
-
-
Brem, R.B.1
Kruglyak, L.2
-
7
-
-
43249129715
-
Gene-environment interaction in yeast gene expression
-
Smith EN, Kruglyak L (2008) Gene-environment interaction in yeast gene expression. PLoS Biol 6:e83.
-
(2008)
PLoS Biol
, vol.6
-
-
Smith, E.N.1
Kruglyak, L.2
-
8
-
-
23644434473
-
Multiple locus linkage analysis of genomewide expression in yeast
-
Storey JD, Akey JM, Kruglyak L (2005) Multiple locus linkage analysis of genomewide expression in yeast. PLoS Biol 3:e267.
-
(2005)
PLoS Biol
, vol.3
-
-
Storey, J.D.1
Akey, J.M.2
Kruglyak, L.3
-
9
-
-
23644434284
-
Genetic interactions between polymorphisms that affect gene expression in yeast
-
Brem RB, Storey JD, Whittle J, Kruglyak L (2005) Genetic interactions between polymorphisms that affect gene expression in yeast. Nature 436:701-703.
-
(2005)
Nature
, vol.436
, pp. 701-703
-
-
Brem, R.B.1
Storey, J.D.2
Whittle, J.3
Kruglyak, L.4
-
10
-
-
45149106353
-
Integrating large-scale functional genomic dadta to dissect the complexity of yeast regulatory networks
-
Zhu J, et al. (2008) Integrating large-scale functional genomic dadta to dissect the complexity of yeast regulatory networks. Nat Genet 40:854-861.
-
(2008)
Nat Genet
, vol.40
, pp. 854-861
-
-
Zhu, J.1
-
11
-
-
34047179422
-
Genetic basis of individual differences in the response to small-molecule drugs in yeast
-
Perlstein EO, Ruderfer DM, Roberts DC, Schreiber SL, Kruglyak L (2007) Genetic basis of individual differences in the response to small-molecule drugs in yeast. Nat Genet 39:496-502.
-
(2007)
Nat Genet
, vol.39
, pp. 496-502
-
-
Perlstein, E.O.1
Ruderfer, D.M.2
Roberts, D.C.3
Schreiber, S.L.4
Kruglyak, L.5
-
13
-
-
0037941585
-
Module networks: Identifying regulatory modules and their condition-specific regulators from gene expression data
-
Segal E, et al. (2003) Module networks: Identifying regulatory modules and their condition-specific regulators from gene expression data. Nat Genet 34:166 -176.
-
(2003)
Nat Genet
, vol.34
, pp. 166-176
-
-
Segal, E.1
-
14
-
-
0034616930
-
Functional discovery via a compendium of expression profiles
-
Hughes TR, et al. (2000) Functional discovery via a compendium of expression profiles. Cell 102:109-126.
-
(2000)
Cell
, vol.102
, pp. 109-126
-
-
Hughes, T.R.1
-
15
-
-
0032052761
-
Oxygen sensing and the transcriptional regulation of oxygen-responsive genes in yeast
-
Kwast KE, Burke PV, Poyton RO (1998) Oxygen sensing and the transcriptional regulation of oxygen-responsive genes in yeast. J Exp Biol 201:1177-1195.
-
(1998)
J Exp Biol
, vol.201
, pp. 1177-1195
-
-
Kwast, K.E.1
Burke, P.V.2
Poyton, R.O.3
-
16
-
-
0033610793
-
The Saccharomyces cerevisiae TCM62 gene encodes a chaperone necessary for the assembly of the mitochondrial succinate dehydrogenase (complex II)
-
Dibrov E, Fu S, Lemire BD (1998) The Saccharomyces cerevisiae TCM62 gene encodes a chaperone necessary for the assembly of the mitochondrial succinate dehydrogenase (complex II). J Biol Chem 273:32042-32048.
-
(1998)
J Biol Chem
, vol.273
, pp. 32042-32048
-
-
Dibrov, E.1
Fu, S.2
Lemire, B.D.3
-
17
-
-
33645769260
-
An improved map of conserved regulatory sites for Saccha-romyces cerevisiae
-
MacIsaac KD, et al. (2006) An improved map of conserved regulatory sites for Saccha-romyces cerevisiae . BMC Bioinformatics 7:113.
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 113
-
-
MacIsaac, K.D.1
-
18
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late-onset families
-
Corder EH, et al. (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late-onset families. Science 261:921-923.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
-
19
-
-
50449091647
-
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
-
McCarroll SA, et al. (2008) Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet 40:1107-1112.
-
(2008)
Nat Genet
, vol.40
, pp. 1107-1112
-
-
McCarroll, S.A.1
-
20
-
-
41649120431
-
A survey of allelic imbalance in F1 mice
-
Campbell CD, Kirby A, Nemesh J, Daly MJ, Hirschhorn JN (2008) A survey of allelic imbalance in F1 mice. Genome Res 18:555-563.
-
(2008)
Genome Res
, vol.18
, pp. 555-563
-
-
Campbell, C.D.1
Kirby, A.2
Nemesh, J.3
Daly, M.J.4
Hirschhorn, J.N.5
-
21
-
-
43249119095
-
-
Fernando MM, et al. (2008) Defining the role of the MHC in autoimmunity: A review and pooled analysis. PLoS Genet 4:e1000024.
-
Fernando MM, et al. (2008) Defining the role of the MHC in autoimmunity: A review and pooled analysis. PLoS Genet 4:e1000024.
-
-
-
-
22
-
-
46449111382
-
Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network
-
Iossifov I, Zheng T, Baron M, Gilliam TC, Rzhetsky A (2008) Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network. Genome Res 18:1150-1162.
-
(2008)
Genome Res
, vol.18
, pp. 1150-1162
-
-
Iossifov, I.1
Zheng, T.2
Baron, M.3
Gilliam, T.C.4
Rzhetsky, A.5
-
23
-
-
42949096140
-
eQED: An efficient method for interpreting eQTL associations using protein networks
-
Suthram S, Beyer A, Karp RM, Eldar Y, Ideker T (2008) eQED: An efficient method for interpreting eQTL associations using protein networks. Mol Syst Biol 4:162.
-
(2008)
Mol Syst Biol
, vol.4
, pp. 162
-
-
Suthram, S.1
Beyer, A.2
Karp, R.M.3
Eldar, Y.4
Ideker, T.5
-
25
-
-
33749037129
-
Identifying regulatory mechanisms using individual variation reveals key role for chromatin modification
-
Lee SI, Pe'er D, Dudley AM, Church GM, Koller D (2006) Identifying regulatory mechanisms using individual variation reveals key role for chromatin modification. Proc Natl Acad Sci USA 103:14062-14067.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 14062-14067
-
-
Lee, S.I.1
Pe'er, D.2
Dudley, A.M.3
Church, G.M.4
Koller, D.5
-
26
-
-
34247556038
-
Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations
-
Zhu J, et al. (2007) Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations. PLoS Comput Biol 3:e69.
-
(2007)
PLoS Comput Biol
, vol.3
-
-
Zhu, J.1
-
27
-
-
40749105508
-
Variations in DNA elucidate molecular networks that cause disease
-
Chen Y, et al. (2008) Variations in DNA elucidate molecular networks that cause disease. Nature 452:429-435.
-
(2008)
Nature
, vol.452
, pp. 429-435
-
-
Chen, Y.1
-
28
-
-
0028877463
-
Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
-
Lander E, Kruglyak L (1995) Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247.
-
(1995)
Nat Genet
, vol.11
, pp. 241-247
-
-
Lander, E.1
Kruglyak, L.2
-
29
-
-
0000576729
-
The significance of the difference between two means when the population variances are unequal
-
Welch BL (1938) The significance of the difference between two means when the population variances are unequal. Biometrika 29:350-362.
-
(1938)
Biometrika
, vol.29
, pp. 350-362
-
-
Welch, B.L.1
-
30
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: A practical and powerful approach to multiple testing. J R Stat Soc B 57:289-300.
-
(1995)
J R Stat Soc B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
|