메뉴 건너뛰기




Volumn 113, Issue 5, 2013, Pages 617-631

Regulation of cardiac L-Type Ca2+ channel CaV1.2 via the β-adrenergic-cAMP-protein kinase a pathway: Old dogmas, advances, and new uncertainties

Author keywords

adrenergic; calcium channels; cyclic AMP dependent protein kinases; heart; molecular mechanism

Indexed keywords

ADRENERGIC RECEPTOR; CALCIUM CHANNEL L TYPE; CYCLIC AMP DEPENDENT PROTEIN KINASE;

EID: 84883440241     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.113.301781     Document Type: Review
Times cited : (96)

References (193)
  • 1
    • 43549098268 scopus 로고    scopus 로고
    • Calcium cycling and signaling in cardiac myocytes
    • Bers DM. Calcium cycling and signaling in cardiac myocytes. Annu Rev Physiol. 2008;70:23-49
    • (2008) Annu Rev Physiol , vol.70 , pp. 23-49
    • Bers, D.M.1
  • 2
    • 78049359992 scopus 로고    scopus 로고
    • Signaling complexes of voltage-gated sodium and calcium channels
    • Catterall WA. Signaling complexes of voltage-gated sodium and calcium channels. Neurosci Lett. 2010;486:107-116
    • (2010) Neurosci Lett , Issue.486 , pp. 107-116
    • Catterall, W.A.1
  • 4
    • 69349100194 scopus 로고    scopus 로고
    • Regulation of basal and reserve cardiac pacemaker function by interactions of cAMP-mediated PKA-dependent Ca2+ cycling with surface membrane channels
    • Vinogradova TM, Lakatta EG. Regulation of basal and reserve cardiac pacemaker function by interactions of cAMP-mediated PKA-dependent Ca2+ cycling with surface membrane channels. J Mol Cell Cardiol. 2009;47:456-474
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 456-474
    • Vinogradova, T.M.1    Lakatta, E.G.2
  • 5
    • 0032953165 scopus 로고    scopus 로고
    • Beta-adrenergic receptors and receptor signaling in heart failure
    • Post SR, Hammond HK, Insel PA. Beta-adrenergic receptors and receptor signaling in heart failure. Annu Rev Pharmacol Toxicol. 1999;39:343-360
    • (1999) Annu Rev Pharmacol Toxicol , vol.39 , pp. 343-360
    • Post, S.R.1    Hammond, H.K.2    Insel, P.A.3
  • 6
    • 3042659100 scopus 로고    scopus 로고
    • Subtype-specific beta-adrenoceptor signaling pathways in the heart and their potential clinical implications
    • Xiao RP, Zhu W, Zheng M, Chakir K, Bond R, Lakatta EG, Cheng H. Subtype-specific beta-adrenoceptor signaling pathways in the heart and their potential clinical implications. Trends Pharmacol Sci. 2004;25:358-365
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 358-365
    • Xiao, R.P.1    Zhu, W.2    Zheng, M.3    Chakir, K.4    Bond, R.5    Lakatta, E.G.6    Cheng, H.7
  • 7
    • 0033607558 scopus 로고    scopus 로고
    • Recent advances in cardiac beta (2)-adrenergic signal transduction
    • Xiao RP, Cheng H, Zhou YY, Kuschel M, Lakatta EG. Recent advances in cardiac beta(2)-adrenergic signal transduction. Circ Res. 1999;85:1092-1100
    • (1999) Circ Res , Issue.85 , pp. 1092-1100
    • Xiao, R.P.1    Cheng, H.2    Zhou, Y.Y.3    Kuschel, M.4    Lakatta, E.G.5
  • 9
    • 84855983508 scopus 로고    scopus 로고
    • Different subcellular populations of L-type Ca2+ channels exhibit unique regulation and functional roles in cardiomyocytes
    • Best JM, Kamp TJ. Different subcellular populations of L-type Ca2+ channels exhibit unique regulation and functional roles in cardiomyocytes. J Mol Cell Cardiol. 2012;52:376-387
    • (2012) J Mol Cell Cardiol , Issue.52 , pp. 376-387
    • Best, J.M.1    Kamp, T.J.2
  • 10
    • 0020693764 scopus 로고
    • Calcium channel modulation by neurotransmitters, enzymes and drugs
    • Reuter H. Calcium channel modulation by neurotransmitters, enzymes and drugs. Nature. 1983;301:569-574
    • (1983) Nature , vol.301 , pp. 569-574
    • Reuter, H.1
  • 11
    • 0020668844 scopus 로고
    • Calcium channels in excitable cell membranes
    • Tsien RW. Calcium channels in excitable cell membranes. Annu Rev Physiol. 1983;45:341-358
    • (1983) Annu Rev Physiol , vol.45 , pp. 341-358
    • Tsien, R.W.1
  • 12
    • 0025273128 scopus 로고
    • Regulation of cardiac L-type calcium current by phosphorylation and G proteins
    • Trautwein W, Hescheler J. Regulation of cardiac L-type calcium current by phosphorylation and G proteins. Annu Rev Physiol. 1990;52:257-274
    • (1990) Annu Rev Physiol , vol.52 , pp. 257-274
    • Trautwein, W.1    Hescheler, J.2
  • 14
    • 0037049999 scopus 로고    scopus 로고
    • Cardiac channelopathies
    • Marbán E. Cardiac channelopathies. Nature. 2002;415:213-218
    • (2002) Nature , vol.415 , pp. 213-218
    • Marbán, E.1
  • 15
    • 67649973701 scopus 로고    scopus 로고
    • Supramolecular assemblies and localized regulation of voltage-gated ion channels
    • Dai S, Hall DD, Hell JW. Supramolecular assemblies and localized regulation of voltage-gated ion channels. Physiol Rev. 2009;89:411-452
    • (2009) Physiol Rev , vol.89 , pp. 411-452
    • Dai, S.1    Hall, D.D.2    Hell, J.W.3
  • 16
    • 79953311130 scopus 로고    scopus 로고
    • Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons
    • Marshall MR, Clark JP 3rd, Westenbroek R, Yu FH, Scheuer T, Catterall WA. Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons. J Biol Chem. 2011;286:12627-12639
    • (2011) J Biol Chem , Issue.286 , pp. 12627-12639
    • Marshall, M.R.1    Clark III, J.P.2    Westenbroek, R.3    Yu, F.H.4    Scheuer, T.5    Catterall, W.A.6
  • 17
    • 82555175873 scopus 로고    scopus 로고
    • Modulation of calcium-dependent inactivation of L-type Ca2+ channels via ß-adrenergic signaling in thalamocortical relay neurons
    • Rankovic V, Landgraf P, Kanyshkova T, Ehling P, Meuth SG, Kreutz MR, Budde T, Munsch T. Modulation of calcium-dependent inactivation of L-type Ca2+ channels via ß-adrenergic signaling in thalamocortical relay neurons. PLoS One. 2011;6:e27474
    • (2011) PLoS One , Issue.6
    • Rankovic, V.1    Landgraf, P.2    Kanyshkova, T.3    Ehling, P.4    Meuth, S.G.5    Kreutz, M.R.6    Budde, T.7    Munsch, T.8
  • 18
    • 0034623827 scopus 로고    scopus 로고
    • Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C.
    • Kamp TJ, Hell JW. Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C. Circ Res. 2000;87:1095-1102
    • (2000) Circ Res , vol.87 , pp. 1095-1102
    • Kamp, T.J.1    Hell, J.W.2
  • 19
    • 0024454626 scopus 로고
    • Protein phosphorylation and compartments of cyclic AMP in the control of cardiac contraction
    • Murray KJ, Reeves ML, England PJ. Protein phosphorylation and compartments of cyclic AMP in the control of cardiac contraction. Mol Cell Biochem. 1989;89:175-179
    • (1989) Mol Cell Biochem , vol.89 , pp. 175-179
    • Murray, K.J.1    Reeves, M.L.2    England, P.J.3
  • 20
    • 33845563635 scopus 로고    scopus 로고
    • Ahnak, a new player in beta-adrenergic regulation of the cardiac L-type Ca2+ channel
    • Haase H. Ahnak, a new player in beta-adrenergic regulation of the cardiac L-type Ca2+ channel. Cardiovasc Res. 2007;73:19-25
    • (2007) Cardiovasc Res , vol.73 , pp. 19-25
    • Haase, H.1
  • 21
    • 0035661773 scopus 로고    scopus 로고
    • Regulation of cardiac and smooth muscle Ca (2+) channels (Ca(V)1.2a,b) by protein kinases
    • Keef KD, Hume JR, Zhong J. Regulation of cardiac and smooth muscle Ca(2+) channels (Ca(V)1.2a,b) by protein kinases. Am J Physiol Cell Physiol. 2001;281:C1743-C1756
    • (2001) Am J Physiol Cell Physiol , Issue.281
    • Keef, K.D.1    Hume, J.R.2    Zhong, J.3
  • 22
    • 11144332992 scopus 로고    scopus 로고
    • Molecular aspects of adrenergic modulation of cardiac L-type Ca2+ channels
    • van der Heyden MA, Wijnhoven TJ, Opthof T. Molecular aspects of adrenergic modulation of cardiac L-type Ca2+ channels. Cardiovasc Res. 2005;65:28-39
    • (2005) Cardiovasc Res , vol.65 , pp. 28-39
    • Van Der Heyden, M.A.1    Wijnhoven, T.J.2    Opthof, T.3
  • 23
    • 58049209252 scopus 로고    scopus 로고
    • Unchanged beta-adrenergic stimulation of cardiac L-type calcium channels in Ca v 1.2 phosphorylation site S1928A mutant mice
    • Lemke T, Welling A, Christel CJ, Blaich A, Bernhard D, Lenhardt P, Hofmann F, Moosmang S. Unchanged beta-adrenergic stimulation of cardiac L-type calcium channels in Ca v 1.2 phosphorylation site S1928A mutant mice. J Biol Chem. 2008;283:34738-34744
    • (2008) J Biol Chem , Issue.283 , pp. 34738-34744
    • Lemke, T.1    Welling, A.2    Christel, C.J.3    Blaich, A.4    Bernhard, D.5    Lenhardt, P.6    Hofmann, F.7    Moosmang, S.8
  • 25
    • 77957256718 scopus 로고    scopus 로고
    • Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels
    • Nichols CB, Rossow CF, Navedo MF, Westenbroek RE, Catterall WA, Santana LF, McKnight GS. Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels. Circ Res. 2010;107:747-756
    • (2010) Circ Res , Issue.107 , pp. 747-756
    • Nichols, C.B.1    Rossow, C.F.2    Navedo, M.F.3    Westenbroek, R.E.4    Catterall, W.A.5    Santana, L.F.6    McKnight, G.S.7
  • 26
    • 84863317895 scopus 로고    scopus 로고
    • Deletion of the C-terminal phosphorylation sites in the cardiac ß-subunit does not affect the basic ß- adrenergic response of the heart and the Ca (v)1.2 channel
    • Brandmayr J, Poomvanicha M, Domes K, Ding J, Blaich A, Wegener JW, Moosmang S, Hofmann F. Deletion of the C-terminal phosphorylation sites in the cardiac ß-subunit does not affect the basic ß- adrenergic response of the heart and the Ca(v)1.2 channel. J Biol Chem. 2012;287:22584-22592
    • (2012) J Biol Chem , vol.287 , pp. 22584-22592
    • Brandmayr, J.1    Poomvanicha, M.2    Domes, K.3    Ding, J.4    Blaich, A.5    Wegener, J.W.6    Moosmang, S.7    Hofmann, F.8
  • 27
    • 0028935585 scopus 로고
    • Regulation of L-type calcium channels of vascular smooth muscle cells
    • Xiong Z, Sperelakis N. Regulation of L-type calcium channels of vascular smooth muscle cells. J Mol Cell Cardiol. 1995;27:75-91
    • (1995) J Mol Cell Cardiol , vol.27 , pp. 75-91
    • Xiong, Z.1    Sperelakis, N.2
  • 28
    • 0034518423 scopus 로고    scopus 로고
    • Structure and regulation of voltage-gated Ca2+ channels
    • Catterall WA. Structure and regulation of voltage-gated Ca2+ channels. Annu Rev Cell Dev Biol. 2000;16:521-555
    • (2000) Annu Rev Cell Dev Biol , vol.16 , pp. 521-555
    • Catterall, W.A.1
  • 30
    • 79955650122 scopus 로고    scopus 로고
    • Microdomain organization and frequency-dependence of CREB-dependent transcriptional signaling in heart cells
    • Kobrinsky E, Duong SQ, Sheydina A, Soldatov NM. Microdomain organization and frequency-dependence of CREB-dependent transcriptional signaling in heart cells. FASEB J. 2011;25:1544-1555
    • (2011) FASEB J. , Issue.25 , pp. 1544-1555
    • Kobrinsky, E.1    Duong, S.Q.2    Sheydina, A.3    Soldatov, N.M.4
  • 31
    • 79958207831 scopus 로고    scopus 로고
    • L-type calcium channel auto-regulation of transcription
    • Satin J, Schroder EA, Crump SM. L-type calcium channel auto-regulation of transcription. Cell Calcium. 2011;49:306-313
    • (2011) Cell Calcium , Issue.49 , pp. 306-313
    • Satin, J.1    Schroder, E.A.2    Crump, S.M.3
  • 32
    • 84861558035 scopus 로고    scopus 로고
    • Ca(V)1 and Ca (V)2 channels engage distinct modes of Ca(2+) signaling to control CREB-dependent gene expression
    • Wheeler DG, Groth RD, Ma H, Barrett CF, Owen SF, Safa P, Tsien RW. Ca(V)1 and Ca(V)2 channels engage distinct modes of Ca(2+) signaling to control CREB-dependent gene expression. Cell. 2012;149:1112-1124
    • (2012) Cell , Issue.149 , pp. 1112-1124
    • Wheeler, D.G.1    Groth, R.D.2    Ma, H.3    Barrett, C.F.4    Owen, S.F.5    Safa, P.6    Tsien, R.W.7
  • 33
    • 46149096244 scopus 로고    scopus 로고
    • Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system
    • Flavell SW, Greenberg ME. Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system. Annu Rev Neurosci. 2008;31:563-590
    • (2008) Annu Rev Neurosci , vol.31 , pp. 563-590
    • Flavell, S.W.1    Greenberg, M.E.2
  • 34
    • 1242319239 scopus 로고    scopus 로고
    • The impact of splice isoforms on voltage- gated calcium channel alpha1 subunits
    • Jurkat-Rott K, Lehmann-Horn F. The impact of splice isoforms on voltage- gated calcium channel alpha1 subunits. J Physiol. 2004;554:609-619
    • (2004) J Physiol , vol.554 , pp. 609-619
    • Jurkat-Rott, K.1    Lehmann-Horn, F.2
  • 35
    • 67649531617 scopus 로고    scopus 로고
    • Alternative splicing of voltage-gated calcium channels: From molecular biology to disease
    • Liao P, Zhang HY, Soong TW. Alternative splicing of voltage-gated calcium channels: From molecular biology to disease. Pflugers Arch. 2009;458:481-487
    • (2009) Pflugers Arch , vol.458 , pp. 481-487
    • Liao, P.1    Zhang, H.Y.2    Soong, T.W.3
  • 36
    • 0030805902 scopus 로고    scopus 로고
    • Identification and subcellular localization of the subunits of L-type calcium channels and adenylyl cyclase in cardiac myocytes
    • Gao T, Puri TS, Gerhardstein BL, Chien AJ, Green RD, Hosey MM. Identification and subcellular localization of the subunits of L-type calcium channels and adenylyl cyclase in cardiac myocytes. J Biol Chem. 1997;272:19401-19407
    • (1997) J Biol Chem , vol.272 , pp. 19401-19407
    • Gao, T.1    Puri, T.S.2    Gerhardstein, B.L.3    Chien, A.J.4    Green, R.D.5    Hosey, M.M.6
  • 38
    • 0029795275 scopus 로고    scopus 로고
    • Specific phosphorylation of a site in the full-length form of the alpha 1 subunit of the cardiac L-type calcium channel by adenosine 3',5'-cyclic monophosphate-dependent protein kinase
    • De Jongh KS, Murphy BJ, Colvin AA, Hell JW, Takahashi M, Catterall WA. Specific phosphorylation of a site in the full-length form of the alpha 1 subunit of the cardiac L-type calcium channel by adenosine 3',5'-cyclic monophosphate-dependent protein kinase. Biochemistry. 1996;35:10392-10402
    • (1996) Biochemistry , vol.35 , pp. 10392-10402
    • De Jongh, K.S.1    Murphy, B.J.2    Colvin, A.A.3    Hell, J.W.4    Takahashi, M.5    Catterall, W.A.6
  • 39
    • 0025840253 scopus 로고
    • Characterization of the two size forms of the alpha 1 subunit of skeletal muscle L-type calcium channels
    • De Jongh KS, Warner C, Colvin AA, Catterall WA. Characterization of the two size forms of the alpha 1 subunit of skeletal muscle L-type calcium channels. Proc Natl Acad Sci U S A. 1991;88:10778-10782
    • (1991) Proc Natl Acad Sci U S A. , vol.88 , pp. 10778-10782
    • De Jongh, K.S.1    Warner, C.2    Colvin, A.A.3    Catterall, W.A.4
  • 42
  • 43
    • 0035877640 scopus 로고    scopus 로고
    • C-terminal fragments of the alpha 1C (CaV1.2) subunit associate with and regulate L-type calcium channels containing C-terminaltruncated alpha 1C subunits
    • Gao T, Cuadra AE, Ma H, Bunemann M, Gerhardstein BL, Cheng T, Eick RT, Hosey MM. C-terminal fragments of the alpha 1C (CaV1.2) subunit associate with and regulate L-type calcium channels containing C-terminaltruncated alpha 1C subunits. J Biol Chem. 2001;276:21089-21097
    • (2001) J Biol Chem , vol.276 , pp. 21089-21097
    • Gao, T.1    Cuadra, A.E.2    Ma, H.3    Bunemann, M.4    Gerhardstein, B.L.5    Cheng, T.6    Eick, R.T.7    Hosey, M.M.8
  • 44
    • 33748098546 scopus 로고    scopus 로고
    • Autoinhibitory control of the CaV1.2 channel by its proteolytically processed distal C-terminal domain
    • Hulme JT, Yarov-Yarovoy V, Lin TW, Scheuer T, Catterall WA. Autoinhibitory control of the CaV1.2 channel by its proteolytically processed distal C-terminal domain. J Physiol. 2006;576:87-102
    • (2006) J Physiol , vol.576 , pp. 87-102
    • Hulme, J.T.1    Yarov-Yarovoy, V.2    Lin, T.W.3    Scheuer, T.4    Catterall, W.A.5
  • 45
    • 0028179146 scopus 로고
    • Calcium channel beta-subunit binds to a conserved motif in the I-II cytoplasmic linker of the alpha 1-subunit
    • Pragnell M, De Waard M, Mori Y, Tanabe T, Snutch TP, Campbell KP. Calcium channel beta-subunit binds to a conserved motif in the I-II cytoplasmic linker of the alpha 1-subunit. Nature. 1994;368:67-70
    • (1994) Nature , vol.368 , pp. 67-70
    • Pragnell, M.1    De Waard, M.2    Mori, Y.3    Tanabe, T.4    Snutch, T.P.5    Campbell, K.P.6
  • 46
    • 77957124347 scopus 로고    scopus 로고
    • The s subunit of voltage-gated Ca2+ channels
    • Buraei Z, Yang J. The s subunit of voltage-gated Ca2+ channels. Physiol Rev. 2010;90:1461-1506
    • (2010) Physiol Rev , Issue.90 , pp. 1461-1506
    • Buraei, Z.1    Yang, J.2
  • 47
    • 84864153599 scopus 로고    scopus 로고
    • Calcium channel auxiliary a2d and ß subunits: Trafficking and one step beyond
    • Dolphin AC. Calcium channel auxiliary a2d and ß subunits: Trafficking and one step beyond. Nat Rev Neurosci. 2012;13:542-555
    • (2012) Nat Rev Neurosci , Issue.13 , pp. 542-555
    • Dolphin, A.C.1
  • 48
    • 0025124412 scopus 로고
    • Beta-adrenergic stimulation of calcium channels occurs by potentiation of high-activity gating modes
    • Yue DT, Herzig S, Marban E. Beta-adrenergic stimulation of calcium channels occurs by potentiation of high-activity gating modes. Proc Natl Acad Sci U S A. 1990;87:753-757
    • (1990) Proc Natl Acad Sci U S A. , vol.87 , pp. 753-757
    • Yue, D.T.1    Herzig, S.2    Marban, E.3
  • 49
    • 0027368612 scopus 로고
    • Mechanisms of betaadrenergic stimulation of cardiac Ca2+ channels revealed by discrete-time Markov analysis of slow gating
    • Herzig S, Patil P, Neumann J, Staschen CM, Yue DT. Mechanisms of betaadrenergic stimulation of cardiac Ca2+ channels revealed by discrete-time Markov analysis of slow gating. Biophys J. 1993;65:1599-1612
    • (1993) Biophys J. , vol.65 , pp. 1599-1612
    • Herzig, S.1    Patil, P.2    Neumann, J.3    Staschen, C.M.4    Yue, D.T.5
  • 50
    • 0022527164 scopus 로고
    • Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists
    • Tsien RW, Bean BP, Hess P, Lansman JB, Nilius B, Nowycky MC. Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists. J Mol Cell Cardiol. 1986;18:691-710
    • (1986) J Mol Cell Cardiol , vol.18 , pp. 691-710
    • Tsien, R.W.1    Bean, B.P.2    Hess, P.3    Lansman, J.B.4    Nilius, B.5    Nowycky, M.C.6
  • 51
    • 0021182780 scopus 로고
    • Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists
    • Hess P, Lansman JB, Tsien RW. Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists. Nature. 1984;311:538-544
    • (1984) Nature , vol.311 , pp. 538-544
    • Hess, P.1    Lansman, J.B.2    Tsien, R.W.3
  • 52
    • 0033781028 scopus 로고    scopus 로고
    • Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels
    • Dzhura I, Wu Y, Colbran RJ, Balser JR, Anderson ME. Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nat Cell Biol. 2000;2:173-177
    • (2000) Nat Cell Biol , vol.2 , pp. 173-177
    • Dzhura, I.1    Wu, Y.2    Colbran, R.J.3    Balser, J.R.4    Anderson, M.E.5
  • 53
    • 0032519842 scopus 로고    scopus 로고
    • Facilitation by the beta2a subunit of pore openings in cardiac Ca2+ channels
    • Pt 1
    • Costantin J, Noceti F, Qin N, Wei X, Birnbaumer L, Stefani E. Facilitation by the beta2a subunit of pore openings in cardiac Ca2+ channels. J Physiol. 1998;507 (Pt 1):93-103
    • (1998) J Physiol , vol.507 , pp. 93-103
    • Costantin, J.1    Noceti, F.2    Qin, N.3    Wei, X.4    Birnbaumer, L.5    Stefani, E.6
  • 54
    • 0025002345 scopus 로고
    • Novel mechanism of voltage-dependent gating in L-type calcium channels
    • Pietrobon D, Hess P. Novel mechanism of voltage-dependent gating in L-type calcium channels. Nature. 1990;346:651-655
    • (1990) Nature , vol.346 , pp. 651-655
    • Pietrobon, D.1    Hess, P.2
  • 55
    • 0028297589 scopus 로고
    • Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells
    • McDonald TF, Pelzer S, Trautwein W, Pelzer DJ. Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells. Physiol Rev. 1994;74:365-507
    • (1994) Physiol Rev , vol.74 , pp. 365-507
    • McDonald, T.F.1    Pelzer, S.2    Trautwein, W.3    Pelzer, D.J.4
  • 56
    • 0842344647 scopus 로고    scopus 로고
    • Physiological modulation of inactivation in L-type Ca2+ channels: One switch
    • Findlay I. Physiological modulation of inactivation in L-type Ca2+ channels: One switch. J Physiol. 2004;554:275-283
    • (2004) J Physiol , vol.554 , pp. 275-283
    • Findlay, I.1
  • 57
    • 0001421246 scopus 로고
    • Some aspects of the biological role of adenosine 3',5'-monophosphate (cyclic AMP).
    • Sutherland EW, Robinson GA, Butcher RW. Some aspects of the biological role of adenosine 3',5'-monophosphate (cyclic AMP). Circulation. 1968;37:279-306
    • (1968) Circulation , vol.37 , pp. 279-306
    • Sutherland, E.W.1    Robinson, G.A.2    Butcher, R.W.3
  • 58
    • 0018337894 scopus 로고
    • Phosphorylation-dephosphorylation of enzymes
    • Krebs EG, Beavo JA. Phosphorylation-dephosphorylation of enzymes. Annu Rev Biochem. 1979;48:923-959
    • (1979) Annu Rev Biochem , vol.48 , pp. 923-959
    • Krebs, E.G.1    Beavo, J.A.2
  • 59
    • 84866729606 scopus 로고    scopus 로고
    • Assembly of allosteric macromolecular switches: Lessons from PKA
    • Taylor SS, Ilouz R, Zhang P, Kornev AP. Assembly of allosteric macromolecular switches: Lessons from PKA. Nat Rev Mol Cell Biol. 2012;13:646-658
    • (2012) Nat Rev Mol Cell Biol , Issue.13 , pp. 646-658
    • Taylor, S.S.1    Ilouz, R.2    Zhang, P.3    Kornev, A.P.4
  • 61
    • 0033954554 scopus 로고    scopus 로고
    • Effects of serine/threonine protein phosphatases on ion channels in excitable membranes
    • Herzig S, Neumann J. Effects of serine/threonine protein phosphatases on ion channels in excitable membranes. Physiol Rev. 2000;80: 173-210
    • (2000) Physiol Rev , vol.80 , pp. 173-210
    • Herzig, S.1    Neumann, J.2
  • 62
    • 0026002028 scopus 로고
    • Dihydropyridine-sensitive calcium channels from skeletal muscle. II. Functional effects of differential phosphorylation of channel subunits
    • Chang CF, Gutierrez LM, Mundina-Weilenmann C, Hosey MM. Dihydropyridine-sensitive calcium channels from skeletal muscle. II. Functional effects of differential phosphorylation of channel subunits. J Biol Chem. 1991;266:16395-16400
    • (1991) J Biol Chem , vol.266 , pp. 16395-16400
    • Chang, C.F.1    Gutierrez, L.M.2    Mundina-Weilenmann, C.3    Hosey, M.M.4
  • 63
    • 0023041553 scopus 로고
    • Purified dihydropyridine-binding site from skeletal muscle t-tubules is a functional calcium channel
    • Flockerzi V, Oeken HJ, Hofmann F, Pelzer D, Cavalié A, Trautwein W. Purified dihydropyridine-binding site from skeletal muscle t-tubules is a functional calcium channel. Nature. 1986;323:66-68
    • (1986) Nature , vol.323 , pp. 66-68
    • Flockerzi, V.1    Oeken, H.J.2    Hofmann, F.3    Pelzer, D.4    Cavalié, A.5    Trautwein, W.6
  • 64
    • 0023773163 scopus 로고
    • Calcium efflux through cardiac calcium channels reconstituted into liposomes-flux measurement with fura-2
    • Kameyama A, Nakayama T. Calcium efflux through cardiac calcium channels reconstituted into liposomes-flux measurement with fura-2. Biochem Biophys Res Commun. 1988;154:1067-1074
    • (1988) Biochem Biophys Res Commun , vol.154 , pp. 1067-1074
    • Kameyama, A.1    Nakayama, T.2
  • 65
    • 0029761155 scopus 로고    scopus 로고
    • Cyclic AMPdependent protein kinase but not protein kinase C regulates the cardiac Ca2+ channel through phosphorylation of its alpha 1 subunit
    • Kameyama A, Shearman MS, Sekiguchi K, Kameyama M. Cyclic AMPdependent protein kinase but not protein kinase C regulates the cardiac Ca2+ channel through phosphorylation of its alpha 1 subunit. J Biochem. 1996;120:170-176
    • (1996) J Biochem , vol.120 , pp. 170-176
    • Kameyama, A.1    Shearman, M.S.2    Sekiguchi, K.3    Kameyama, M.4
  • 66
    • 0024728731 scopus 로고
    • Activation of purified calcium channels by stoichiometric protein phosphorylation
    • Nunoki K, Florio V, Catterall WA. Activation of purified calcium channels by stoichiometric protein phosphorylation. Proc Natl Acad Sci U S A. 1989;86:6816-6820
    • (1989) Proc Natl Acad Sci U S A. , vol.86 , pp. 6816-6820
    • Nunoki, K.1    Florio, V.2    Catterall, W.A.3
  • 67
    • 0024203072 scopus 로고
    • Dihydropyridine and phenylalkylamine receptors associated with cardiac and skeletal muscle calcium channels are structurally different
    • Chang FC, Hosey MM. Dihydropyridine and phenylalkylamine receptors associated with cardiac and skeletal muscle calcium channels are structurally different. J Biol Chem. 1988;263:18929-18937
    • (1988) J Biol Chem , vol.263 , pp. 18929-18937
    • Chang, F.C.1    Hosey, M.M.2
  • 68
    • 0027372328 scopus 로고
    • Phosphorylation of the L-type calcium channel beta subunit is involved in beta-adrenergic signal transduction in canine myocardium
    • Haase H, Karczewski P, Beckert R, Krause EG. Phosphorylation of the L-type calcium channel beta subunit is involved in beta-adrenergic signal transduction in canine myocardium. FEBS Lett. 1993;335:217-222
    • (1993) FEBS Lett , vol.335 , pp. 217-222
    • Haase, H.1    Karczewski, P.2    Beckert, R.3    Krause, E.G.4
  • 69
    • 0024328801 scopus 로고
    • Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel
    • Mikami A, Imoto K, Tanabe T, Niidome T, Mori Y, Takeshima H, Narumiya S, Numa S. Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel. Nature. 1989;340:230-233
    • (1989) Nature , vol.340 , pp. 230-233
    • Mikami, A.1    Imoto, K.2    Tanabe, T.3    Niidome, T.4    Mori, Y.5    Takeshima, H.6    Narumiya, S.7    Numa, S.8
  • 70
    • 0029758087 scopus 로고    scopus 로고
    • Identification of PK-A phosphorylation sites in the carboxyl terminus of L-type calcium channel alpha 1 subunits
    • Mitterdorfer J, Froschmayr M, Grabner M, Moebius FF, Glossmann H, Striessnig J. Identification of PK-A phosphorylation sites in the carboxyl terminus of L-type calcium channel alpha 1 subunits. Biochemistry. 1996;35:9400-9406
    • (1996) Biochemistry , vol.35 , pp. 9400-9406
    • Mitterdorfer, J.1    Froschmayr, M.2    Grabner, M.3    Moebius, F.F.4    Glossmann, H.5    Striessnig, J.6
  • 71
    • 33750804385 scopus 로고
    • Phosphorylation of Serine in the distal C-terminal domain of cardiac CaV1.2 channels during beta1-adrenergic regulation
    • Hulme JT, Westenbroek RE, Scheuer T, Catterall WA. Phosphorylation of serine 1928 in the distal C-terminal domain of cardiac CaV1.2 channels during beta1-adrenergic regulation. Proc Natl Acad Sci U S A. 2006;103:16574-16579
    • (1928) Proc Natl Acad Sci U S A. , vol.2006 , Issue.103 , pp. 16574-16579
    • Hulme, J.T.1    Westenbroek, R.E.2    Scheuer, T.3    Catterall, W.A.4
  • 72
    • 80053945719 scopus 로고    scopus 로고
    • Adenylyl cyclase/cAMP-PKA-mediated phosphorylation of basal L-type Ca2+ channels in mouse embryonic ventricular myocytes
    • Yan X, Gao S, Tang M, Xi J, Gao L, Zhu M, Luo H, Hu X, Zheng Y, Hescheler J, Liang H. Adenylyl cyclase/cAMP-PKA-mediated phosphorylation of basal L-type Ca2+ channels in mouse embryonic ventricular myocytes. Cell Calcium. 2011;50:433-443
    • (2011) Cell Calcium , Issue.50 , pp. 433-443
    • Yan, X.1    Gao, S.2    Tang, M.3    Xi, J.4    Gao, L.5    Zhu, M.6    Luo, H.7    Hu, X.8    Zheng, Y.9    Hescheler, J.10    Liang, H.11
  • 75
    • 82555168148 scopus 로고    scopus 로고
    • Protein Kinase D Regulates The Human Cardiac L-type Voltage-gated Calcium Channel Through Serine 1884
    • Aita Y, Kurebayashi N, Hirose S, Maturana AD. Protein kinase D regulates the human cardiac L-type voltage-gated calcium channel through serine 1884. FEBS Lett. 2011;585:3903-3906
    • (2011) FEBS Lett , Issue.585 , pp. 3903-3906
    • Aita, Y.1    Kurebayashi, N.2    Hirose, S.3    Maturana, A.D.4
  • 76
    • 78649863650 scopus 로고    scopus 로고
    • Beta-adrenergicregulated phosphorylation of the skeletal muscle Ca (V)1.1 channel in the fight-or-flight response
    • Emrick MA, Sadilek M, Konoki K, Catterall WA. Beta-adrenergicregulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response. Proc Natl Acad Sci U S A. 2010;107:18712-18717
    • (2010) Proc Natl Acad Sci U S A. , vol.107 , pp. 18712-18717
    • Emrick, M.A.1    Sadilek, M.2    Konoki, K.3    Catterall, W.A.4
  • 77
    • 0039136238 scopus 로고    scopus 로고
    • Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the beta (2) subunit
    • Bünemann M, Gerhardstein BL, Gao T, Hosey MM. Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the beta(2) subunit. J Biol Chem. 1999;274:33851-33854
    • (1999) J Biol Chem , Issue.274 , pp. 33851-33854
    • Bünemann, M.1    Gerhardstein, B.L.2    Gao, T.3    Hosey, M.M.4
  • 78
    • 0029750390 scopus 로고    scopus 로고
    • In-vivo phosphorylation of the cardiac L-type calcium channel beta-subunit in response to catecholamines
    • Haase H, Bartel S, Karczewski P, Morano I, Krause EG. In-vivo phosphorylation of the cardiac L-type calcium channel beta-subunit in response to catecholamines. Mol Cell Biochem. 1996;163-164:99-106
    • (1996) Mol Cell Biochem , vol.163-164 , pp. 99-106
    • Haase, H.1    Bartel, S.2    Karczewski, P.3    Morano, I.4    Krause, E.G.5
  • 79
    • 0033543140 scopus 로고    scopus 로고
    • Identification of the sites phosphorylated by cyclic AMP-dependent protein kinase on the beta 2 subunit of L-type voltage-dependent calcium channels
    • Gerhardstein BL, Puri TS, Chien AJ, Hosey MM. Identification of the sites phosphorylated by cyclic AMP-dependent protein kinase on the beta 2 subunit of L-type voltage-dependent calcium channels. Biochemistry. 1999;38:10361-10370
    • (1999) Biochemistry , vol.38 , pp. 10361-10370
    • Gerhardstein, B.L.1    Puri, T.S.2    Chien, A.J.3    Hosey, M.M.4
  • 81
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J. 2000;351:95-105
    • (2000) Biochem J. , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 82
    • 0015217645 scopus 로고
    • Purification and characterization of a protein inhibitor of adenosine 3',5'-monophosphate-dependent protein kinases
    • Walsh DA, Ashby CD, Gonzalez C, Calkins D, Fischer EH. Krebs EG: Purification and characterization of a protein inhibitor of adenosine 3',5'-monophosphate-dependent protein kinases. J Biol Chem. 1971;246:1977-1985
    • (1971) J Biol Chem , vol.246 , pp. 1977-1985
    • Walsh, D.A.1    Ashby, C.D.2    Gonzalez, C.3    Calkins, D.4    Fischer, E.H.5    Krebs, E.G.6
  • 84
    • 0015523833 scopus 로고
    • Characterization of the interaction of a protein inhibitor with adenosine 3',5'-monophosphate-dependent protein kinases. I. Interaction with the catalytic subunit of the protein kinase
    • Ashby CD, Walsh DA. Characterization of the interaction of a protein inhibitor with adenosine 3',5'-monophosphate-dependent protein kinases. I. Interaction with the catalytic subunit of the protein kinase. J Biol Chem. 1972;247:6637-6642
    • (1972) J Biol Chem , Issue.247 , pp. 6637-6642
    • Ashby, C.D.1    Walsh, D.A.2
  • 85
    • 0026326821 scopus 로고
    • Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
    • Knighton DR, Zheng JH, Ten Eyck LF, Xuong NH, Taylor SS, Sowadski JM. Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science. 1991;253:414-420
    • (1991) Science , vol.253 , pp. 414-420
    • Knighton, D.R.1    Zheng, J.H.2    Ten Eyck, L.F.3    Xuong, N.H.4    Taylor, S.S.5    Sowadski, J.M.6
  • 86
    • 0025733341 scopus 로고
    • Isolation and characterization of cDNA clones for an inhibitor protein of cAMP-dependent protein kinase
    • Olsen SR, Uhler MD. Isolation and characterization of cDNA clones for an inhibitor protein of cAMP-dependent protein kinase. J Biol Chem. 1991;266:11158-11162
    • (1991) J Biol Chem , vol.266 , pp. 11158-11162
    • Olsen, S.R.1    Uhler, M.D.2
  • 87
    • 0022381201 scopus 로고
    • On the mechanism of betaadrenergic regulation of the Ca channel in the guinea-pig heart
    • Kameyama M, Hofmann F, Trautwein W. On the mechanism of betaadrenergic regulation of the Ca channel in the guinea-pig heart. Pflugers Arch. 1985;405:285-293
    • (1985) Pflugers Arch , vol.405 , pp. 285-293
    • Kameyama, M.1    Hofmann, F.2    Trautwein, W.3
  • 88
    • 0022474217 scopus 로고
    • Modulation of Ca current during the phosphorylation cycle in the guinea pig heart
    • Kameyama M, Hescheler J, Hofmann F, Trautwein W. Modulation of Ca current during the phosphorylation cycle in the guinea pig heart. Pflugers Arch. 1986;407:123-128
    • (1986) Pflugers Arch , vol.407 , pp. 123-128
    • Kameyama, M.1    Hescheler, J.2    Hofmann, F.3    Trautwein, W.4
  • 89
    • 0026093740 scopus 로고
    • Role of the GTP-binding protein Gs in the beta-adrenergic modulation of cardiac Ca channels
    • Cavalié A, Allen TJ, Trautwein W. Role of the GTP-binding protein Gs in the beta-adrenergic modulation of cardiac Ca channels. Pflugers Arch. 1991;419:433-443
    • (1991) Pflugers Arch , vol.419 , pp. 433-443
    • Cavalié, A.1    Allen, T.J.2    Trautwein, W.3
  • 90
    • 0025356601 scopus 로고
    • Wholecell calcium current in guinea-pig ventricular myocytes dialysed with guanine nucleotides
    • Shuba YM, Hesslinger B, Trautwein W, McDonald TF, Pelzer D. Wholecell calcium current in guinea-pig ventricular myocytes dialysed with guanine nucleotides. J Physiol. 1990;424:205-228
    • (1990) J Physiol , vol.424 , pp. 205-228
    • Shuba, Y.M.1    Hesslinger, B.2    Trautwein, W.3    McDonald, T.F.4    Pelzer, D.5
  • 91
    • 0025851846 scopus 로고
    • Sympathetic regulation of cardiac calcium current is due exclusively to cAMP-dependent phosphorylation
    • Hartzell HC, Méry PF, Fischmeister R, Szabo G. Sympathetic regulation of cardiac calcium current is due exclusively to cAMP-dependent phosphorylation. Nature. 1991;351:573-576
    • (1991) Nature , vol.351 , pp. 573-576
    • Hartzell, H.C.1    Méry, P.F.2    Fischmeister, R.3    Szabo, G.4
  • 92
    • 0030809055 scopus 로고    scopus 로고
    • Effects of protein phosphatase and kinase inhibitors on Ca2+ and Cl- currents in guinea pig ventricular myocytes
    • Hirayama Y, Hartzell HC. Effects of protein phosphatase and kinase inhibitors on Ca2+ and Cl- currents in guinea pig ventricular myocytes. Mol Pharmacol. 1997;52:725-734
    • (1997) Mol Pharmacol , vol.52 , pp. 725-734
    • Hirayama, Y.1    Hartzell, H.C.2
  • 93
    • 0030809185 scopus 로고    scopus 로고
    • Beta-2 adrenergic activation of L-type Ca++ current in cardiac myocytes
    • Skeberdis VA, Jurevicius J, Fischmeister aR. Beta-2 adrenergic activation of L-type Ca++ current in cardiac myocytes. J Pharmacol Exp Ther. 1997;283:452-461
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 452-461
    • Skeberdis, V.A.1    Jurevicius, J.2    Fischmeistera, R.3
  • 96
    • 0023758453 scopus 로고
    • The stimulatory G protein of adenylyl cyclase, Gs, also stimulates dihydropyridine-sensitive Ca2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist
    • Yatani A, Imoto Y, Codina J, Hamilton SL, Brown AM, Birnbaumer L. The stimulatory G protein of adenylyl cyclase, Gs, also stimulates dihydropyridine-sensitive Ca2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist. J Biol Chem. 1988;263:9887-9895
    • (1988) J Biol Chem , vol.263 , pp. 9887-9895
    • Yatani, A.1    Imoto, Y.2    Codina, J.3    Hamilton, S.L.4    Brown, A.M.5    Birnbaumer, L.6
  • 97
    • 0025159817 scopus 로고
    • Membrane-delimited stimulation of heart cell calcium current by beta-adrenergic signal-transducing Gs protein
    • Pelzer S, Shuba YM, Asai T, Codina J, Birnbaumer L, McDonald TF, Pelzer D. Membrane-delimited stimulation of heart cell calcium current by beta-adrenergic signal-transducing Gs protein. Am J Physiol. 1990;259:H264-H267
    • (1990) Am J Physiol , vol.259
    • Pelzer, S.1    Shuba, Y.M.2    Asai, T.3    Codina, J.4    Birnbaumer, L.5    McDonald, T.F.6    Pelzer, D.7
  • 98
    • 0024375272 scopus 로고
    • Rapid beta-adrenergic modulation of cardiac calcium channel currents by a fast G protein pathway
    • Yatani A, Brown AM. Rapid beta-adrenergic modulation of cardiac calcium channel currents by a fast G protein pathway. Science. 1989;245:71-74
    • (1989) Science , vol.245 , pp. 71-74
    • Yatani, A.1    Brown, A.M.2
  • 99
    • 0027214363 scopus 로고
    • A comparative analysis of the time course of cardiac Ca2+ current response to rapid applications of beta-adrenergic and dihydropyridine agonists
    • Méry PF, Frace AM, Hartzell HC, Fischmeister R. A comparative analysis of the time course of cardiac Ca2+ current response to rapid applications of beta-adrenergic and dihydropyridine agonists. Naunyn Schmiedebergs Arch Pharmacol. 1993;348:197-206
    • (1993) Naunyn Schmiedebergs Arch Pharmacol , vol.348 , pp. 197-206
    • Méry, P.F.1    Frace, A.M.2    Hartzell, H.C.3    Fischmeister, R.4
  • 100
    • 43449095725 scopus 로고    scopus 로고
    • Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: Role of phosphodiesterases
    • Leroy J, Abi-Gerges A, Nikolaev VO, Richter W, Lechêne P, Mazet JL, Conti M, Fischmeister R, Vandecasteele G. Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: Role of phosphodiesterases. Circ Res. 2008;102:1091-1100
    • (2008) Circ Res , vol.102 , pp. 1091-1100
    • Leroy, J.1    Abi-Gerges, A.2    Nikolaev, V.O.3    Richter, W.4    Lechêne, P.5    Mazet, J.L.6    Conti, M.7    Fischmeister, R.8    Vandecasteele, G.9
  • 101
    • 0142243420 scopus 로고    scopus 로고
    • Regulation of L-type Ca2+ channels in the heart: Overview of recent advances
    • Yamaoka K, Kameyama M. Regulation of L-type Ca2+ channels in the heart: Overview of recent advances. Mol Cell Biochem. 2003;253:3-13
    • (2003) Mol Cell Biochem , vol.253 , pp. 3-13
    • Yamaoka, K.1    Kameyama, M.2
  • 102
    • 0342314167 scopus 로고
    • Injection of protein kinase inhibitor into cultured heart cells blocks calcium slow channels
    • Bkaily G, Sperelakis N. Injection of protein kinase inhibitor into cultured heart cells blocks calcium slow channels. Am J Physiol. 1984;246:H630-H634
    • (1984) Am J Physiol , vol.246
    • Bkaily, G.1    Sperelakis, N.2
  • 103
    • 0040613702 scopus 로고
    • Voltage-activated calcium channels that must be phosphorylated to respond to membrane depolarization
    • Armstrong D, Eckert R. Voltage-activated calcium channels that must be phosphorylated to respond to membrane depolarization. Proc Natl Acad Sci U S A. 1987;84:2518-2522
    • (1987) Proc Natl Acad Sci U S A. , vol.84 , pp. 2518-2522
    • Armstrong, D.1    Eckert, R.2
  • 104
    • 1942517938 scopus 로고    scopus 로고
    • Protein phosphatase 1 and an opposing protein kinase regulate steady-state L-type Ca2+ current in mouse cardiac myocytes
    • duBell WH, Rogers TB. Protein phosphatase 1 and an opposing protein kinase regulate steady-state L-type Ca2+ current in mouse cardiac myocytes. J Physiol. 2004;556:79-93
    • (2004) J Physiol , vol.556 , pp. 79-93
    • Du Bell, W.H.1    Rogers, T.B.2
  • 105
    • 0037144097 scopus 로고    scopus 로고
    • L-type Ca2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices
    • Chen X, Piacentino V 3rd, Furukawa S, Goldman B, Margulies KB, Houser SR. L-type Ca2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices. Circ Res. 2002;91:517-524
    • (2002) Circ Res , vol.91 , pp. 517-524
    • Chen, X.1    Piacentino III, V.2    Furukawa, S.3    Goldman, B.4    Margulies, K.B.5    Houser, S.R.6
  • 106
    • 84862815375 scopus 로고    scopus 로고
    • Protein phosphatase 2A effectively modulates basal L-type Ca (2+) current by dephosphorylating Ca(v)1.2 at serine 1866 in mouse cardiac myocytes
    • Shi J, Gu P, Zhu Z, Liu J, Chen Z, Sun X, Chen W, Gao X, Zhang Z. Protein phosphatase 2A effectively modulates basal L-type Ca(2+) current by dephosphorylating Ca(v)1.2 at serine 1866 in mouse cardiac myocytes. Biochem Biophys Res Commun. 2012;418:792-798
    • (2012) Biochem Biophys Res Commun , vol.418 , pp. 792-798
    • Shi, J.1    Gu, P.2    Zhu, Z.3    Liu, J.4    Chen, Z.5    Sun, X.6    Chen, W.7    Gao, X.8    Zhang, Z.9
  • 107
    • 36148946749 scopus 로고    scopus 로고
    • Simulated ischemia enhances L-type calcium current in pacemaker cells isolated from the rabbit sinoatrial node
    • Du YM, Nathan RD. Simulated ischemia enhances L-type calcium current in pacemaker cells isolated from the rabbit sinoatrial node. Am J Physiol Heart Circ Physiol. 2007;293:H2986-H2994
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Du, Y.M.1    Nathan, R.D.2
  • 108
    • 0028961069 scopus 로고
    • Acetylcholine elicits a rebound stimulation of Ca2+ current mediated by pertussis toxin-sensitive G protein and cAMP-dependent protein kinase A in atrial myocytes
    • Wang YG, Lipsius SL. Acetylcholine elicits a rebound stimulation of Ca2+ current mediated by pertussis toxin-sensitive G protein and cAMP-dependent protein kinase A in atrial myocytes. Circ Res. 1995;76:634-644
    • (1995) Circ Res , vol.76 , pp. 634-644
    • Wang, Y.G.1    Lipsius, S.L.2
  • 109
    • 56649106667 scopus 로고    scopus 로고
    • Calmodulin kinase II activation is required for the maintenance of basal activity of L-type Ca2+ channels in guinea-pig ventricular myocytes
    • Hao LY, Xu JJ, Minobe E, Kameyama A, Kameyama M. Calmodulin kinase II activation is required for the maintenance of basal activity of L-type Ca2+ channels in guinea-pig ventricular myocytes. J Pharmacol Sci. 2008;108:290-300
    • (2008) J Pharmacol Sci , vol.108 , pp. 290-300
    • Hao, L.Y.1    Xu, J.J.2    Minobe, E.3    Kameyama, A.4    Kameyama, M.5
  • 110
    • 0036903878 scopus 로고    scopus 로고
    • Cytoskeletal disrupting agents prevent calmodulin kinase, IQ domain and voltage-dependent facilitation of L-type Ca2+ channels
    • Dzhura I, Wu Y, Colbran RJ, Corbin JD, Balser JR, Anderson ME. Cytoskeletal disrupting agents prevent calmodulin kinase, IQ domain and voltage-dependent facilitation of L-type Ca2+ channels. J Physiol. 2002;545:399-406
    • (2002) J Physiol , vol.545 , pp. 399-406
    • Dzhura, I.1    Wu, Y.2    Colbran, R.J.3    Corbin, J.D.4    Balser, J.R.5    Anderson, M.E.6
  • 113
    • 0027329805 scopus 로고
    • Two phosphatase sites on the Ca2+ channel affecting different kinetic functions
    • Ono K, Fozzard HA. Two phosphatase sites on the Ca2+ channel affecting different kinetic functions. J Physiol. 1993;470:73-84
    • (1993) J Physiol , vol.470 , pp. 73-84
    • Ono, K.1    Fozzard, H.A.2
  • 114
    • 48249116482 scopus 로고    scopus 로고
    • PIP2 is a necessary cofactor for ion channel function: How and why?
    • Suh BC, Hille B. PIP2 is a necessary cofactor for ion channel function: How and why? Annu Rev Biophys. 2008;37:175-195
    • (2008) Annu Rev Biophys , vol.37 , pp. 175-195
    • Suh, B.C.1    Hille, B.2
  • 115
    • 0037206832 scopus 로고    scopus 로고
    • Dual regulation of voltagegated calcium channels by PtdIns( 4, 5)P2
    • Wu L, Bauer CS, Zhen XG, Xie C, Yang J. Dual regulation of voltagegated calcium channels by PtdIns(4,5)P2. Nature. 2002;419:947-952
    • (2002) Nature , vol.419 , pp. 947-952
    • Wu, L.1    Bauer, C.S.2    Zhen, X.G.3    Xie, C.4    Yang, J.5
  • 116
    • 33749460024 scopus 로고    scopus 로고
    • A single amino acid mutation attenuates rundown of voltage-gated calcium channels
    • Zhen XG, Xie C, Yamada Y, Zhang Y, Doyle C, Yang J. A single amino acid mutation attenuates rundown of voltage-gated calcium channels. FEBS Lett. 2006;580:5733-5738
    • (2006) FEBS Lett , vol.580 , pp. 5733-5738
    • Zhen, X.G.1    Xie, C.2    Yamada, Y.3    Zhang, Y.4    Doyle, C.5    Yang, J.6
  • 117
    • 77955488732 scopus 로고    scopus 로고
    • Modulation of high-voltage activated Ca (2+) channels by membrane phosphatidylinositol 4,5-bisphosphate
    • Suh BC, Leal K, Hille B. Modulation of high-voltage activated Ca(2+) channels by membrane phosphatidylinositol 4,5-bisphosphate. Neuron. 2010;67:224-238
    • (2010) Neuron , Issue.67 , pp. 224-238
    • Suh, B.C.1    Leal, K.2    Hille, B.3
  • 118
    • 0027509511 scopus 로고
    • Cardiac pacemaking in the sinoatrial node
    • Irisawa H, Brown HF, Giles W. Cardiac pacemaking in the sinoatrial node. Physiol Rev. 1993;73:197-227
    • (1993) Physiol Rev , vol.73 , pp. 197-227
    • Irisawa, H.1    Brown, H.F.2    Giles, W.3
  • 119
    • 0026699335 scopus 로고
    • Phosphorylation restores activity of L-type calcium channels after rundown in inside-out patches from rabbit cardiac cells
    • Ono K, Fozzard HA. Phosphorylation restores activity of L-type calcium channels after rundown in inside-out patches from rabbit cardiac cells. J Physiol. 1992;454:673-688
    • (1992) J Physiol , vol.454 , pp. 673-688
    • Ono, K.1    Fozzard, H.A.2
  • 120
    • 0025964175 scopus 로고
    • Calpastatin and nucleotides stabilize cardiac calcium channel activity in excised patches
    • Romanin C, Grösswagen P, Schindler H. Calpastatin and nucleotides stabilize cardiac calcium channel activity in excised patches. Pflugers Arch. 1991;418:86-92
    • (1991) Pflugers Arch , vol.418 , pp. 86-92
    • Romanin, C.1    Grösswagen, P.2    Schindler, H.3
  • 121
    • 0033082119 scopus 로고    scopus 로고
    • A cytoplasmic factor, calpastatin and ATP together reverse run-down of Ca2+ channel activity in guineapig heart
    • Pt 3
    • Hao LY, Kameyama A, Kameyama M. A cytoplasmic factor, calpastatin and ATP together reverse run-down of Ca2+ channel activity in guineapig heart. J Physiol. 1999;514(Pt 3):687-699
    • (1999) J Physiol , vol.514 , pp. 687-699
    • Hao, L.Y.1    Kameyama, A.2    Kameyama, M.3
  • 122
    • 8644255945 scopus 로고    scopus 로고
    • Calmodulin reverses rundown of L-type Ca (2+) channels in guinea pig ventricular myocytes
    • Xu JJ, Hao LY, Kameyama A, Kameyama M. Calmodulin reverses rundown of L-type Ca(2+) channels in guinea pig ventricular myocytes. Am J Physiol Cell Physiol. 2004;287:C1717-C1724
    • (2004) Am J Physiol Cell Physiol , Issue.287
    • Xu, J.J.1    Hao, L.Y.2    Kameyama, A.3    Kameyama, M.4
  • 123
    • 77950636256 scopus 로고    scopus 로고
    • Calmodulin- and Ca2+-dependent facilitation and inactivation of the Cav1.2 Ca2+ channels in guinea-pig ventricular myocytes
    • Han DY, Minobe E, Wang WY, Guo F, Xu JJ, Hao LY, Kameyama M. Calmodulin- and Ca2+-dependent facilitation and inactivation of the Cav1.2 Ca2+ channels in guinea-pig ventricular myocytes. J Pharmacol Sci. 2010;112:310-319
    • (2010) J Pharmacol Sci , Issue.112 , pp. 310-319
    • Han, D.Y.1    Minobe, E.2    Wang, W.Y.3    Guo, F.4    Xu, J.J.5    Hao, L.Y.6    Kameyama, M.7
  • 124
    • 84862128440 scopus 로고    scopus 로고
    • Ca2+-dependent modulation of voltage-gated Ca2+ channels
    • Christel C, Lee A. Ca2+-dependent modulation of voltage-gated Ca2+ channels. Biochim Biophys Acta. 2012;1820:1243-1252
    • (2012) Biochim Biophys Acta , vol.1820 , pp. 1243-1252
    • Christel, C.1    Lee, A.2
  • 125
    • 84877359523 scopus 로고    scopus 로고
    • Competition between a-actinin and Ca2+-calmodulin controls surface retention of the L-type Ca2+ channel Ca (V)1.2
    • Hall DD, Dai S, Tseng PY, et al. Competition between a-actinin and Ca2+-calmodulin controls surface retention of the L-type Ca2+ channel Ca(V)1.2. Neuron. 2013;78:483-497
    • (2013) Neuron , Issue.78 , pp. 483-497
    • Hall, D.D.1    Dai, S.2    Tseng, P.Y.3
  • 127
    • 79953303621 scopus 로고    scopus 로고
    • Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo
    • Fu Y, Westenbroek RE, Yu FH, Clark JP 3rd, Marshall MR, Scheuer T, Catterall WA. Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo. J Biol Chem. 2011;286:12617-12626
    • (2011) J Biol Chem , Issue.286 , pp. 12617-12626
    • Fu, Y.1    Westenbroek, R.E.2    Yu, F.H.3    Clark III, J.P.4    Marshall, M.R.5    Scheuer, T.6    Catterall, W.A.7
  • 128
    • 33750433556 scopus 로고    scopus 로고
    • The C terminus of the L-type voltage-gated calcium channel Ca (V)1.2 encodes a transcription factor
    • Gomez-Ospina N, Tsuruta F, Barreto-Chang O, Hu L, Dolmetsch R. The C terminus of the L-type voltage-gated calcium channel Ca(V)1.2 encodes a transcription factor. Cell. 2006;127:591-606
    • (2006) Cell , Issue.127 , pp. 591-606
    • Gomez-Ospina, N.1    Tsuruta, F.2    Barreto-Chang, O.3    Hu, L.4    Dolmetsch, R.5
  • 129
    • 67650264043 scopus 로고    scopus 로고
    • L-type calcium channel C terminus autoregulates transcription
    • Schroder E, Byse M, Satin J. L-type calcium channel C terminus autoregulates transcription. Circ Res. 2009;104:1373-1381
    • (2009) Circ Res , vol.104 , pp. 1373-1381
    • Schroder, E.1    Byse, M.2    Satin, J.3
  • 130
  • 132
    • 84873314764 scopus 로고    scopus 로고
    • The cardiac L-type calcium channel distal carboxy terminus autoinhibition is regulated by calcium
    • Crump SM, Andres DA, Sievert G, Satin J. The cardiac L-type calcium channel distal carboxy terminus autoinhibition is regulated by calcium. Am J Physiol Heart Circ Physiol. 2013;304:H455-H464
    • (2013) Am J Physiol Heart Circ Physiol , Issue.304
    • Crump, S.M.1    Andres, D.A.2    Sievert, G.3    Satin, J.4
  • 133
    • 0029591843 scopus 로고
    • Roles of a membrane-localized beta subunit in the formation and targeting of functional L-type Ca2+ channels
    • Chien AJ, Zhao X, Shirokov RE, Puri TS, Chang CF, Sun D, Rios E, Hosey MM. Roles of a membrane-localized beta subunit in the formation and targeting of functional L-type Ca2+ channels. J Biol Chem. 1995;270:30036-30044
    • (1995) J Biol Chem , vol.270 , pp. 30036-30044
    • Chien, A.J.1    Zhao, X.2    Shirokov, R.E.3    Puri, T.S.4    Chang, C.F.5    Sun, D.6    Rios, E.7    Hosey, M.M.8
  • 134
    • 0032504167 scopus 로고    scopus 로고
    • Crucial role of N terminus in function of cardiac L-type Ca2+ channel and its modulation by protein kinase C
    • Shistik E, Ivanina T, Blumenstein Y, Dascal N. Crucial role of N terminus in function of cardiac L-type Ca2+ channel and its modulation by protein kinase C. J Biol Chem. 1998;273:17901-17909
    • (1998) J Biol Chem , vol.273 , pp. 17901-17909
    • Shistik, E.1    Ivanina, T.2    Blumenstein, Y.3    Dascal, N.4
  • 135
    • 0028970740 scopus 로고
    • Ca2+ current enhancement by alpha 2/delta and beta subunits in Xenopus oocytes: Contribution of changes in channel gating and alpha 1 protein level
    • Pt1
    • Shistik E, Ivanina T, Puri T, Hosey M, Dascal N. Ca2+ current enhancement by alpha 2/delta and beta subunits in Xenopus oocytes: Contribution of changes in channel gating and alpha 1 protein level. J Physiol. 1995;489(Pt 1):55-62
    • (1995) J Physiol , vol.489 , pp. 55-62
    • Shistik, E.1    Ivanina, T.2    Puri, T.3    Hosey, M.4    Dascal, N.5
  • 136
    • 0034708683 scopus 로고    scopus 로고
    • Proteolytic processing of the C terminus of the alpha(1C) subunit of L-type calcium channels and the role of a proline-rich domain in membrane tethering of proteolytic fragments
    • Gerhardstein BL, Gao T, Bünemann M, Puri TS, Adair A, Ma H, Hosey MM. Proteolytic processing of the C terminus of the alpha(1C) subunit of L-type calcium channels and the role of a proline-rich domain in membrane tethering of proteolytic fragments. J Biol Chem. 2000;275:8556-8563
    • (2000) J Biol Chem , vol.275 , pp. 8556-8563
    • Gerhardstein, B.L.1    Gao, T.2    Bünemann, M.3    Puri, T.S.4    Adair, A.5    Ma, H.6    Hosey, M.M.7
  • 137
    • 0028175280 scopus 로고
    • Modification of Ca2+ channel activity by deletions at the carboxyl terminus of the cardiac alpha 1 subunit
    • Wei X, Neely A, Lacerda AE, Olcese R, Stefani E, Perez-Reyes E, Birnbaumer L. Modification of Ca2+ channel activity by deletions at the carboxyl terminus of the cardiac alpha 1 subunit. J Biol Chem. 1994;269:1635-1640
    • (1994) J Biol Chem , vol.269 , pp. 1635-1640
    • Wei, X.1    Neely, A.2    Lacerda, A.E.3    Olcese, R.4    Stefani, E.5    Perez-Reyes, E.6    Birnbaumer, L.7
  • 139
    • 0028941490 scopus 로고
    • Dual activation of the cardiac Ca2+ channel alpha 1C-subunit and its modulation by the beta-subunit
    • Neely A, Olcese R, Baldelli P, Wei X, Birnbaumer L, Stefani E. Dual activation of the cardiac Ca2+ channel alpha 1C-subunit and its modulation by the beta-subunit. Am J Physiol. 1995;268:C732-C740
    • (1995) Am J Physiol , vol.268
    • Neely, A.1    Olcese, R.2    Baldelli, P.3    Wei, X.4    Birnbaumer, L.5    Stefani, E.6
  • 140
    • 0026742961 scopus 로고
    • Specific phosphorylation of a COOH-terminal site on the full-length form of the alpha 1 subunit of the skeletal muscle calcium channel by cAMP-dependent protein kinase
    • Rotman EI, De Jongh KS, Florio V, Lai Y, Catterall WA. Specific phosphorylation of a COOH-terminal site on the full-length form of the alpha 1 subunit of the skeletal muscle calcium channel by cAMP-dependent protein kinase. J Biol Chem. 1992;267:16100-16105
    • (1992) J Biol Chem , vol.267 , pp. 16100-16105
    • Rotman, E.I.1    De Jongh, K.S.2    Florio, V.3    Lai, Y.4    Catterall, W.A.5
  • 141
    • 0029126336 scopus 로고
    • Involvement of the carboxyl-terminal region of the alpha 1 subunit in voltagedependent inactivation of cardiac calcium channels
    • Klöckner U, Mikala G, Varadi M, Varadi G, Schwartz A. Involvement of the carboxyl-terminal region of the alpha 1 subunit in voltagedependent inactivation of cardiac calcium channels. J Biol Chem. 1995;270:17306-17310
    • (1995) J Biol Chem , vol.270 , pp. 17306-17310
    • Klöckner, U.1    Mikala, G.2    Varadi, M.3    Varadi, G.4    Schwartz, A.5
  • 142
    • 0029915158 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons
    • Hell JW, Westenbroek RE, Breeze LJ, Wang KK, Chavkin C, Catterall WA. N-methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons. Proc Natl Acad Sci U S A. 1996;93:3362-3367
    • (1996) Proc Natl Acad Sci U S A. , vol.93 , pp. 3362-3367
    • Hell, J.W.1    Westenbroek, R.E.2    Breeze, L.J.3    Wang, K.K.4    Chavkin, C.5    Catterall, W.A.6
  • 143
    • 0023947092 scopus 로고
    • Run-down of the Ca current during long whole-cell recordings in guinea pig heart cells: Role of phosphorylation and intracellular calcium
    • Belles B, Malécot CO, Hescheler J, Trautwein W. "Run-down" of the Ca current during long whole-cell recordings in guinea pig heart cells: Role of phosphorylation and intracellular calcium. Pflugers Arch. 1988;411:353-360
    • (1988) Pflugers Arch , vol.411 , pp. 353-360
    • Belles, B.1    Malécot, C.O.2    Hescheler, J.3    Trautwein, W.4
  • 144
    • 0028045950 scopus 로고
    • Cardiac calcium channels expressed in Xenopus oocytes are modulated by dephosphorylation but not by cAMP-dependent phosphorylation
    • Singer-Lahat D, Lotan I, Biel M, Flockerzi V, Hofmann F, Dascal N. Cardiac calcium channels expressed in Xenopus oocytes are modulated by dephosphorylation but not by cAMP-dependent phosphorylation. Receptors Channels. 1994;2:215-226
    • (1994) Receptors Channels , vol.2 , pp. 215-226
    • Singer-Lahat, D.1    Lotan, I.2    Biel, M.3    Flockerzi, V.4    Hofmann, F.5    Dascal, N.6
  • 145
    • 0028212976 scopus 로고
    • Regulation of the cloned L-type cardiac calcium channel by cyclic-AMP-dependent protein kinase
    • Perez-Reyes E, Yuan W, Wei X, Bers DM. Regulation of the cloned L-type cardiac calcium channel by cyclic-AMP-dependent protein kinase. FEBS Lett. 1994;342:119-123
    • (1994) FEBS Lett , vol.342 , pp. 119-123
    • Perez-Reyes, E.1    Yuan, W.2    Wei, X.3    Bers, D.M.4
  • 147
    • 0030007989 scopus 로고    scopus 로고
    • A potential site of functional modulation by protein kinase A in the cardiac Ca2+ channel alpha 1C subunit
    • Perets T, Blumenstein Y, Shistik E, Lotan I, Dascal N. A potential site of functional modulation by protein kinase A in the cardiac Ca2+ channel alpha 1C subunit. FEBS Lett. 1996;384:189-192
    • (1996) FEBS Lett , vol.384 , pp. 189-192
    • Perets, T.1    Blumenstein, Y.2    Shistik, E.3    Lotan, I.4    Dascal, N.5
  • 148
    • 34447283760 scopus 로고    scopus 로고
    • AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signaling
    • Oliveria SF, Dell'Acqua ML, Sather WA. AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signaling. Neuron. 2007;55:261-275
    • (2007) Neuron , vol.55 , pp. 261-275
    • Oliveria, S.F.1    Dell'Acqua, M.L.2    Sather, W.A.3
  • 150
    • 0023774366 scopus 로고
    • Use-dependent reduction and facilitation of Ca2+ current in guinea-pig myocytes
    • Fedida D, Noble D, Spindler AJ. Use-dependent reduction and facilitation of Ca2+ current in guinea-pig myocytes. J Physiol. 1988;405:439-460
    • (1988) J Physiol , vol.405 , pp. 439-460
    • Fedida, D.1    Noble, D.2    Spindler, A.J.3
  • 151
    • 0019395344 scopus 로고
    • Voltage-dependent potentiation of the slow inward current in frog atrium
    • Noble S, Shimoni Y. Voltage-dependent potentiation of the slow inward current in frog atrium. J Physiol. 1981;310:77-95
    • (1981) J Physiol , vol.310 , pp. 77-95
    • Noble, S.1    Shimoni, Y.2
  • 153
    • 78650842356 scopus 로고    scopus 로고
    • Progress in the structural understanding of voltage-gated calcium channel (CaV) function and modulation
    • Minor DL Jr, Findeisen F. Progress in the structural understanding of voltage-gated calcium channel (CaV) function and modulation. Channels (Austin). 2010;4:459-474
    • (2010) Channels (Austin). , Issue.4 , pp. 459-474
    • Minor Jr., D.L.1    Findeisen, F.2
  • 154
    • 84862296973 scopus 로고    scopus 로고
    • Calmodulindependent protein kinase II: Linking heart failure and arrhythmias
    • Swaminathan PD, Purohit A, Hund TJ, Anderson ME. Calmodulindependent protein kinase II: Linking heart failure and arrhythmias. Circ Res. 2012;110:1661-1677
    • (2012) Circ Res , Issue.110 , pp. 1661-1677
    • Swaminathan, P.D.1    Purohit, A.2    Hund, T.J.3    Anderson, M.E.4
  • 155
    • 0021488253 scopus 로고
    • Facilitation of Ca2+-channel currents in bovine adrenal chromaffin cells
    • Hoshi T, Rothlein J, Smith SJ. Facilitation of Ca2+-channel currents in bovine adrenal chromaffin cells. Proc Natl Acad Sci U S A. 1984;81:5871-5875
    • (1984) Proc Natl Acad Sci U S A. , vol.81 , pp. 5871-5875
    • Hoshi, T.1    Rothlein, J.2    Smith, S.J.3
  • 156
    • 0344197075 scopus 로고    scopus 로고
    • G protein modulation of voltage-gated calcium channels
    • Dolphin AC. G protein modulation of voltage-gated calcium channels. Pharmacol Rev. 2003;55:607-627
    • (2003) Pharmacol Rev , vol.55 , pp. 607-627
    • Dolphin, A.C.1
  • 157
    • 33751517370 scopus 로고    scopus 로고
    • Direct G protein modulation of Cav2 calcium channels
    • Tedford HW, Zamponi GW. Direct G protein modulation of Cav2 calcium channels. Pharmacol Rev. 2006;58:837-862
    • (2006) Pharmacol Rev , vol.58 , pp. 837-862
    • Tedford, H.W.1    Zamponi, G.W.2
  • 158
    • 0033952557 scopus 로고    scopus 로고
    • Voltage-dependent facilitation of cardiac L-type Ca channels expressed in HEK-293 cells requires ß subunit
    • Kamp TJ, Hu H, Marban E. Voltage-dependent facilitation of cardiac L-type Ca channels expressed in HEK-293 cells requires ß subunit. Am J Physiol. 2000;278:H126-136
    • (2000) Am J Physiol , vol.278
    • Kamp, T.J.1    Hu, H.2    Marban, E.3
  • 160
    • 0032951697 scopus 로고    scopus 로고
    • The role of subunit composition on prepulse facilitation of the cardiac L-type calcium channel
    • Dai S, Klugbauer N, Zong X, Seisenberger C, Hofmann F. The role of subunit composition on prepulse facilitation of the cardiac L-type calcium channel. FEBS Lett. 1999;442:70-74
    • (1999) FEBS Lett , vol.442 , pp. 70-74
    • Dai, S.1    Klugbauer, N.2    Zong, X.3    Seisenberger, C.4    Hofmann, F.5
  • 161
    • 0032541069 scopus 로고    scopus 로고
    • Promotion and inhibition of L-type Ca2+ channel facilitation by distinct domains of the subunit
    • Cens T, Restituito S, Vallentin A, Charnet P. Promotion and inhibition of L-type Ca2+ channel facilitation by distinct domains of the subunit. J Biol Chem. 1998;273:18308-18315
    • (1998) J Biol Chem , vol.273 , pp. 18308-18315
    • Cens, T.1    Restituito, S.2    Vallentin, A.3    Charnet, P.4
  • 164
    • 0030760304 scopus 로고    scopus 로고
    • Camp-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits
    • Gao T, Yatani A, Dell'Acqua ML, Sako H, Green SA, Dascal N, Scott JD, Hosey MM. cAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits. Neuron. 1997;19:185-196
    • (1997) Neuron , vol.19 , pp. 185-196
    • Gao, T.1    Yatani, A.2    Dell'Acqua, M.L.3    Sako, H.4    Green, S.A.5    Dascal, N.6    Scott, J.D.7    Hosey, M.M.8
  • 165
    • 0029417345 scopus 로고
    • Camp-dependent phosphorylation of the cardiac L-type Ca channel: A missing link?
    • Charnet P, Lory P, Bourinet E, Collin T, Nargeot J. cAMP-dependent phosphorylation of the cardiac L-type Ca channel: A missing link? Biochimie. 1995;77:957-962
    • (1995) Biochimie , vol.77 , pp. 957-962
    • Charnet, P.1    Lory, P.2    Bourinet, E.3    Collin, T.4    Nargeot, J.5
  • 166
    • 0023043827 scopus 로고
    • Expression and modulation of voltage-gated calcium channels after RNA injection in Xenopus oocytes
    • Dascal N, Snutch TP, Lübbert H, Davidson N, Lester HA. Expression and modulation of voltage-gated calcium channels after RNA injection in Xenopus oocytes. Science. 1986;231:1147-1150
    • (1986) Science , vol.231 , pp. 1147-1150
    • Dascal, N.1    Snutch, T.P.2    Lübbert, H.3    Davidson, N.4    Lester, H.A.5
  • 167
    • 0026529975 scopus 로고
    • Cyclic AMP-dependent modulation of cardiac Ca channels expressed in Xenopus laevis oocytes
    • Lory P, Nargeot J. Cyclic AMP-dependent modulation of cardiac Ca channels expressed in Xenopus laevis oocytes. Biochem Biophys Res Commun. 1992;182:1059-1065
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 1059-1065
    • Lory, P.1    Nargeot, J.2
  • 168
    • 0027425580 scopus 로고
    • Voltage-dependent potentiation of the activity of cardiac L-type calcium channel alpha 1 subunits due to phosphorylation by cAMP-dependent protein kinase
    • Sculptoreanu A, Rotman E, Takahashi M, Scheuer T, Catterall WA. Voltage-dependent potentiation of the activity of cardiac L-type calcium channel alpha 1 subunits due to phosphorylation by cAMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1993;90:10135-10139
    • (1993) Proc Natl Acad Sci U S A. , vol.90 , pp. 10135-10139
    • Sculptoreanu, A.1    Rotman, E.2    Takahashi, M.3    Scheuer, T.4    Catterall, W.A.5
  • 169
    • 0026757556 scopus 로고
    • Cyclic AMP-dependent phosphorylation and regulation of the cardiac dihydropyridine- sensitive Ca channel
    • Yoshida A, Takahashi M, Nishimura S, Takeshima H, Kokubun S. Cyclic AMP-dependent phosphorylation and regulation of the cardiac dihydropyridine- sensitive Ca channel. FEBS Lett. 1992;309:343-349
    • (1992) FEBS Lett , vol.309 , pp. 343-349
    • Yoshida, A.1    Takahashi, M.2    Nishimura, S.3    Takeshima, H.4    Kokubun, S.5
  • 170
    • 0035951378 scopus 로고    scopus 로고
    • Ser(1901) of alpha(1C) subunit is required for the PKA-mediated enhancement of L-type Ca (2+) channel currents but not for the negative shift of activation
    • Naguro I, Nagao T, Adachi-Akahane S. Ser(1901) of alpha(1C) subunit is required for the PKA-mediated enhancement of L-type Ca(2+) channel currents but not for the negative shift of activation. FEBS Lett. 2001;489:87-91
    • (2001) FEBS Lett , vol.489 , pp. 87-91
    • Naguro, I.1    Nagao, T.2    Adachi-Akahane, S.3
  • 171
    • 42049118530 scopus 로고    scopus 로고
    • Role of CaVbeta subunits, and lack of functional reserve, in protein
    • Miriyala J, Nguyen T, Yue DT, Colecraft HM. Role of CaVbeta subunits, and lack of functional reserve, in protein kinase A modulation of cardiac CaV1.2 channels. Circ Res. 2008;102:e54-e64
    • (2008) Circ Res , vol.102
    • Miriyala, J.1    Nguyen, T.2    Yue, D.T.3    Colecraft, H.M.4
  • 173
    • 33644849507 scopus 로고    scopus 로고
    • Betaadrenergic Stimulation Of L-type Ca2+ Channels In Cardiac Myocytes Requires The Distal Carboxyl Terminus Of Alpha1C But Not Serine 1928
    • Ganesan AN, Maack C, Johns DC, Sidor A, O'Rourke B. Betaadrenergic stimulation of L-type Ca2+ channels in cardiac myocytes requires the distal carboxyl terminus of alpha1C but not serine 1928. Circ Res. 2006;98:e11-e18
    • (2006) Circ Res , Issue.98
    • Ganesan, A.N.1    Maack, C.2    Johns, D.C.3    Sidor, A.4    O'Rourke, B.5
  • 174
    • 84871417418 scopus 로고    scopus 로고
    • Modulation Of Distinct Isoforms Of L-type Calcium Channels By G(q)- Coupled Receptors In Xenopus Oocytes: Antagonistic Effects Of Gß? And Protein Kinase C
    • Weiss S, Keren-Raifman T, Oz S, Ben Mocha A, Haase H, Dascal N. Modulation of distinct isoforms of L-type calcium channels by G(q)- coupled receptors in Xenopus oocytes: Antagonistic effects of Gß? and protein kinase C. Channels (Austin). 2012;6:426-437
    • (2012) Channels (Austin) , Issue.6 , pp. 426-437
    • Weiss, S.1    Keren-Raifman, T.2    Oz, S.3    Ben Mocha, A.4    Haase, H.5    Dascal, N.6
  • 175
    • 33746381639 scopus 로고    scopus 로고
    • AKAP signaling complexes: Getting to the heart of the matter
    • McConnachie G, Langeberg LK, Scott JD. AKAP signaling complexes: Getting to the heart of the matter. Trends Mol Med. 2006;12:317-323
    • (2006) Trends Mol Med , vol.12 , pp. 317-323
    • McConnachie, G.1    Langeberg, L.K.2    Scott, J.D.3
  • 176
    • 0035834749 scopus 로고    scopus 로고
    • Receptor number and caveolar co-localization determine receptor coupling efficiency to adenylyl cyclase
    • Ostrom RS, Gregorian C, Drenan RM, Xiang Y, Regan JW, Insel PA. Receptor number and caveolar co-localization determine receptor coupling efficiency to adenylyl cyclase. J Biol Chem. 2001;276:42063-42069
    • (2001) J Biol Chem , vol.276 , pp. 42063-42069
    • Ostrom, R.S.1    Gregorian, C.2    Drenan, R.M.3    Xiang, Y.4    Regan, J.W.5    Insel, P.A.6
  • 177
    • 33646592211 scopus 로고    scopus 로고
    • Localization of cardiac L-type Ca (2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation
    • Balijepalli RC, Foell JD, Hall DD, Hell JW, Kamp TJ. Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation. Proc Natl Acad Sci U S A. 2006;103:7500-7505
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7500-7505
    • Balijepalli, R.C.1    Foell, J.D.2    Hall, D.D.3    Hell, J.W.4    Kamp, T.J.5
  • 181
    • 84864877375 scopus 로고    scopus 로고
    • Anchoring proteins as regulators of signaling pathways
    • Perino A, Ghigo A, Scott JD, Hirsch E. Anchoring proteins as regulators of signaling pathways. Circ Res. 2012;111:482-492
    • (2012) Circ Res , Issue.111 , pp. 482-492
    • Perino, A.1    Ghigo, A.2    Scott, J.D.3    Hirsch, E.4
  • 182
    • 0242331601 scopus 로고    scopus 로고
    • Betaadrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15
    • Hulme JT, Lin TW, Westenbroek RE, Scheuer T, Catterall WA. Betaadrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15. Proc Natl Acad Sci U S A. 2003;100:13093-13098
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 13093-13098
    • Hulme, J.T.1    Lin, T.W.2    Westenbroek, R.E.3    Scheuer, T.4    Catterall, W.A.5
  • 183
    • 33846982906 scopus 로고    scopus 로고
    • Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons
    • Hall DD, Davare MA, Shi M, Allen ML, Weisenhaus M, McKnight GS, Hell JW. Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons. Biochemistry. 2007;46:1635-1646
    • (2007) Biochemistry , vol.46 , pp. 1635-1646
    • Hall, D.D.1    Davare, M.A.2    Shi, M.3    Allen, M.L.4    Weisenhaus, M.5    McKnight, G.S.6    Hell, J.W.7
  • 184
    • 0037040223 scopus 로고    scopus 로고
    • A novel leucine zipper targets AKAP15 and cyclic AMP-dependent protein kinase to the C terminus of the skeletal muscle Ca2+ channel and modulates its function
    • Hulme JT, Ahn M, Hauschka SD, Scheuer T, Catterall WA. A novel leucine zipper targets AKAP15 and cyclic AMP-dependent protein kinase to the C terminus of the skeletal muscle Ca2+ channel and modulates its function. J Biol Chem. 2002;277:4079-4087
    • (2002) J Biol Chem , vol.277 , pp. 4079-4087
    • Hulme, J.T.1    Ahn, M.2    Hauschka, S.D.3    Scheuer, T.4    Catterall, W.A.5
  • 185
    • 0033563033 scopus 로고    scopus 로고
    • Regulation of L-type Ca2+ channels in rabbit portal vein by G protein alphas and betagamma subunits
    • Pt1
    • Zhong J, Dessauer CW, Keef KD, Hume Jr. Regulation of L-type Ca2+ channels in rabbit portal vein by G protein alphas and betagamma subunits. J Physiol. 1999;517(Pt 1):109-120
    • (1999) J Physiol , vol.517 , pp. 109-120
    • Zhong, J.1    Dessauer, C.W.2    Keef, K.D.3    Hume, J.R.4
  • 190
    • 84874039308 scopus 로고    scopus 로고
    • Ca2+-independent activation of Ca2+/ calmodulin-dependent protein kinase II bound to the C-terminal domain of CaV2.1 calcium channels
    • Magupalli VG, Mochida S, Yan J, Jiang X, Westenbroek RE, Nairn AC, Scheuer T, Catterall WA. Ca2+-independent activation of Ca2+/ calmodulin-dependent protein kinase II bound to the C-terminal domain of CaV2.1 calcium channels. J Biol Chem. 2013;288:4637-4648
    • (2013) J Biol Chem , vol.288 , pp. 4637-4648
    • Magupalli, V.G.1    Mochida, S.2    Yan, J.3    Jiang, X.4    Westenbroek, R.E.5    Nairn, A.C.6    Scheuer, T.7    Catterall, W.A.8
  • 191
    • 0026590639 scopus 로고
    • Beta-subunit expression is required for cAMP-dependent increase of cloned cardiac and vascular calcium channel currents
    • Klöckner U, Itagaki K, Bodi I, Schwartz A. Beta-subunit expression is required for cAMP-dependent increase of cloned cardiac and vascular calcium channel currents. Pflugers Arch. 1992;420:413-415
    • (1992) Pflugers Arch , vol.420 , pp. 413-415
    • Klöckner, U.1    Itagaki, K.2    Bodi, I.3    Schwartz, A.4
  • 192
    • 0026566261 scopus 로고
    • Endogenous Xenopusoocyte Ca-channels are regulated by protein kinases A and C.
    • Bourinet E, Fournier F, Nargeot J, Charnet P. Endogenous Xenopusoocyte Ca-channels are regulated by protein kinases A and C. FEBS Lett. 1992;299:5-9
    • (1992) FEBS Lett , vol.299 , pp. 5-9
    • Bourinet, E.1    Fournier, F.2    Nargeot, J.3    Charnet, P.4
  • 193
    • 0033996163 scopus 로고    scopus 로고
    • Developmental regulation of the L-type calcium channel alpha1C subunit expression in heart
    • Liu L, O'Hara DS, Cala SE, Poornima I, Hines RN, Marsh JD. Developmental regulation of the L-type calcium channel alpha1C subunit expression in heart. Mol Cell Biochem. 2000;205:101-109
    • (2000) Mol Cell Biochem , vol.205 , pp. 101-109
    • Liu, L.1    O'Hara, D.S.2    Cala, S.E.3    Poornima, I.4    Hines, R.N.5    Marsh, J.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.