Facilitation by the β(2a) subunit of pore openings in cardiac Ca2+ channels

Journal of Physiology

Volumn 507, Issue 1, 1998, Pages 93-103

  Costantin, James ^a   Noceti, Francesca ^a   Qin, Ning ^a   Wei, Xiangyang ^c   Birnbaumer, Lutz ^a   Stefani, Enrico ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Conicet ^*  (Argentina)

^c Box 951778 ^*

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; PROTEIN SUBUNIT; 1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; CALCIUM CHANNEL STIMULATING AGENT; CALCIUM CHANNEL ALPHA 1C SUBUNIT; CALCIUM CHANNEL BETA 2A SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DEPOLARIZATION; GENE OVEREXPRESSION; NONHUMAN; OOCYTE; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOPUS; ANIMAL; DRUG EFFECT; FEMALE; HEART MUSCLE; METABOLISM; PHYSIOLOGY; PROBABILITY; MOLECULAR BIOLOGY; PATCH CLAMP TECHNIQUE;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; ANIMALS; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNELS; FEMALE; ION CHANNEL GATING; MYOCARDIUM; OOCYTES; PATCH-CLAMP TECHNIQUES; PROBABILITY; XENOPUS;

EID: 0032519842     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1998.093bu.x     Document Type: Article

References (27)

1. BEAN, B. P. (1989). Neurotransmitter inhibition of neuronal calcium currents by changes in channel voltage dependence. Nature 340, 153-156.
2. BEAN, B. P. (1990). Calcium channels: gating for the physiologist. Nature 348, 192-193.
3. BROWNLEE, K. A. (1965). Statistical Theory and Methodology in Science and Engineering. Wiley, New York.
4. CATTERALL, W. A. (1991). Functional subunit structure of voltage-gated calcium channels. Science 253, 1499-1500.
5. DELCOUR, A. H. & TSIEN, R. W. (1993). Altered prevalence of gating modes in neurotransmitter inhibition of N-type calcium channels. Science 259, 980-984.
6. HESS, P., LANSMAN, J. B. & TSIEN, R. W. (1984). Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists. Nature 311, 538-544.
7. 2+ channel diversity. Annual Review of Neuroscience 17, 399-418.
8. 2+ channel. Nature 352, 527-530.
9. 2+ channel alpha 1 subunit as expressed in mouse L cells. FEBS Letters 315, 167-172.
10. MCDONALD, T. F., PELZER, S., TRAUTWEIN, W. & PELZER, D. J. (1994). Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells. Physiological Reviews 74, 365-507.
11. 2+ binding reactions. Journal of General Physiology 82, 511-542.
12. NEELY, A., WEI, X., OLCESE, R., BIRNBAUMER, L. & STEFANI, E. (1993). Potentiation by the β subunit of the ratio of the ionic current to the charge movement in the cardiac calcium channel. Science 262, 575-578.
13. OLCESE, R., QIN, N., SCHNEIDER, T., NEELY, A., WEI, X., STEFANI, E. & BIRNBAUMER, L. (1994). The amino terminus of a calcium channel β subunit sets rates of channel inactivation independently of the subunit's effect on activation. Neuron 13, 1433-1438.
14. 1 and β subunits. Journal of General Physiology 105, 289-306.
15. PEREZ-REYES, E., CASTELLANO, A., KIM, H. S., BERTRAND, P., BAGGSTROM, E., LACERDA, A. E., WEI, X., BIRNBAUMER, L. & WEI, X. Y. (1992). Cloning and expression of cardiac/brain β subunit of the L-type calcium channel. Journal of Biological Chemistry 267, 1792-1797.
16. 1-subunit of the dihydropyridine receptor from skeletal muscle. Nature 340, 233-236.
17. PIETROBON, D. & HESS, P. (1990). Novel mechanism of voltage-dependent gating in L-type calcium channels. Nature 346, 651-655.
18. PLUMMER, M. R. & HESS, P. (1991). Reversible uncoupling of inactivation in N-type calcium channels. Nature 351, 657-659.
19. REUTER, H., STEVENS, C. F., TSIEN, R. W. & YELLEN, G. (1982). Properties of single calcium channels in cardiac cell culture. Nature 297, 501-504.
20. RITTENHOUSE, A. R. & HESS, P. (1994). Microscopic heterogeneity in unitary N-type calcium currents in rat sympathetic neurons. Journal of Physiology 474, 87-99.
21. SIGWORTH, F. J. & SINE, S. M. (1987). Data transformations from improved display and fitting of single channel dwell time histograms. Biophysical Journal 52, 1047-1054.
22. SINGER, D., BIEL, M., LOTAN, I., FLOCKERZI, V., HOFMANN, F. & DASCAL, N. (1991). The roles of the subunits in the function of the calcium channel. Science 253, 1553-1557.
23. VANDONGEN, A. M. (1996). A new algorithm for idealizing single ion channel data containing multiple unknown conductance levels. Biophysical Journal 70, 1303-1315.
24. VARADI, G., LORY, P., SCHULTZ, D., VARADI, M. & SCHWARTZ, A. (1991). Acceleration of activation and inactivation by the beta subunit of the skeletal muscle calcium channel. Nature 352, 159-162.
25. 2+ channels. Journal of Biological Chemistry 266, 21943-21947.
26. WILLIAMS, M. E., FELDMAN, D. H., MCCUE, A. F., BRENNER, R., VELICELEBI, G., ELLIS, S. B. & HARPOLD, M. M. (1992). Structure and functional expression of alpha 1, alpha 2, and beta subunits of a novel human neuronal calcium channel subtype. Neuron 8, 71-84.
27. ZAR, J. H. (1974). Biostatistical Analysis. Prentice-Hall, Englewood Cliffs, NJ, USA.