Molecular aspects of adrenergic modulation of cardiac L-type Ca 2+ channels

Cardiovascular Research

Volumn 65, Issue 1, 2005, Pages 28-39

  Van Der Heyden, Marcel A G ^a   Wijnhoven, Tessa J M ^a   Opthof, Tobias ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Adrenergic (ant)agonists; Ca (cellular); Ca channel; G proteins; Protein kinase A; Protein kinase C; Protein kinase G; Protein phosphatase; Protein phosphorylation; Second messengers; Tyrosine protein kinase

Indexed keywords

ADENYLATE CYCLASE; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CALCIUM CHANNEL L TYPE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN KINASE C; PROTEIN TYROSINE KINASE;

ADRENERGIC SYSTEM; CALCIUM CURRENT; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART; HUMAN; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR INTRINSIC ACTIVITY; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION;

ADRENERGIC AGENTS; AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; HUMANS; ION CHANNEL GATING; MOLECULAR SEQUENCE DATA; MYOCARDIUM; PROTEIN KINASES; RECEPTORS, ADRENERGIC; SEQUENCE ALIGNMENT;

EID: 11144332992     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2004.09.028     Document Type: Review

References (89)

1. R.K. Orkand, and R. Niedergerke Heart action potential dependance on external calcium and sodium ions Science 146 1964 1176 1177
2. M.J. Janse, and A.L. Wit Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction Physiol. Rev. 69 1989 1040 1169
3. L.B. Salkoff, and M.A. Tanouye Genetics of ion channels Physiol. Rev. 66 1986 301 329
4. M.P. Davies, R.H. An, P. Doevendans, S. Kubalak, K.R. Chien, and R.S. Kass Developmental changes in ionic channel activity in the embryonic murine heart Circ. Res. 78 1996 15 25
5. M.A.G. Van der Heyden, J. Hescheler, and C.L. Mummery Spotlight on stem cells-makes old hearts fresh Cardiovasc. Res. 58 2003 241 245
6. J. Hescheler, B.K. Fleischman, S. Lentini, V.A. Maltsev, J. Rohwedel, and A.M. Wobus Embryonic stem cells: a model to study structural and functional properties in cardiomyogenesis Cardiovasc. Res. 36 1997 149 162
7. C. Mummery, D. Ward-Van Oostwaard, P. Doevendans, R. Spijker, S. Van den Brink, and R. Hassink Differentiation of human embryonic stem cells to cardiomyocytes. Role of coculture with visceral endoderm-like cells Circulation 107 2003 2733 2740
8. M.A.G. Van der Heyden, M.J.A. Van Kempen, Y. Tsuji, M.B. Rook, H.J. Jongsma, and T. Opthof P19 embryonal carcinoma cells: a suitable model system for cardiac electrophysiological differentiation at the molecular and functional level Cardiovasc. Res. 58 2003 410 422
9. H. Reuter Calcium channel modulation by neurotransmitters, enzymes and drugs Nature 301 1983 569 574
10. H. Irisawa, H.F. Brown, and W.R. Giles Cardiac pacemaking in the sinoatrial node Physiol. Rev. 73 1993 197 227
11. M.-C. Wang, R.F. Collins, R.C. Ford, N.S. Berrow, A.C. Dolphin, and A. Kitmitto The three-dimensional structure of the cardiac L-type voltage-gated calcium channel J. Biol. Chem. 279 2004 7159 7168
12. M.-C. Wang, A. Dolphin, and A. Kitmitto L-type voltage-gated calcium channels: understanding function through structure FEBS Lett. 564 2004 245 250
13. v1.2a,b) by protein kinases Am. J. Physiol. Cell Physiol. 281 2001 C1743 C1756
14. 2+ channels Annu. Rev. Dev. Biol. 16 2000 521 555
15. L.H. Jiang, D.J. Gawler, N. Hodson, C.J. Milligan, H.A. Pearson, and V. Porter Regulation of cloned cardiac L-type calcium channels by cGMP-dependent protein kinase J. Biol. Chem. 275 2000 6135 6143
16. M.M. Hosey, A.J. Chien, and T.S. Puri Structure and regulation of L-type calcium channels: a current assessment of the properties and roles of channel subunits Trends Cardiovasc. Med. 6 1996 265 273
17. 2+ channels Cell Physiol. Biochem. 9 1999 242 269
18. R.I. Norman, and R.N. Leach Subunit structure and phosphorylation of the cardiac L-type calcium channel Biochem. Soc. Trans. 22 1994 492 495
19. D. Pelzer, S. Pelzer, and T.F. McDonald Properties and regulation of calcium channels in muscle cells Rev. Physiol. Biochem. Pharmacol. 114 1990 107 207
20. T.F. McDonald, S. Pelzer, W. Trautwein, and D.J. Pelzer Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells Physiol. Rev. 74 1994 365 507
21. V.A. Maltsev, A.M. Wobus, J. Rohwedel, M. Bader, and J. Hescheler Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents Circ. Res. 75 1994 233 244
22. H.C. Hartzell, and I. Duchatelle-Gourdon Structure and neural modulation of cardiac calcium channels J. Cardiovasc. Electrophysiol. 3 1992 567 578
23. 2+ currents from newborn rat cardiomyocytes in primary culture Pflügers Arch. 428 1994 241 249
24. T. Osaka, and R.W. Joyner Developmental changes in calcium currents of rabbit ventricular cells Circ. Res. 68 1991 788 796
25. M. Wibo, G. Bravo, and T. Godfraind Postnatal maturation of excitation-contraction coupling in rat ventricle in relation to the subcellular localization and surface density of 1,4 dihydropyridine and ryanodine receptors Circ. Res. 68 1991 662 673
26. 2+ currents in rat ventricular myocytes Am. J. Physiol. Heart Circ. Physiol. 279 2000 H889 H900
27. R.J. Lefkowitz, H.A. Rockman, and W.J. Koch Catecholamines, cardiac β-adrenergic receptors, and heart failure Circulation 101 2000 1634 1637
28. O.E. Brodde, and M.C. Michel Adrenergic and muscarinic receptors in the human heart Pharmacol. Rev. 51 1999 651 690
29. 2+ channels Biophys. J. 79 2000 2547 2556
30. i proteins Circ. Res. 87 2000 635 637
31. 3-Adrenoceptors in the heart Cardiovasc. Res. 56 2002 353 356
32. T. Maki, E.J. Gruver, A.J. Davidoff, N. Izzo, D. Toupin, and W. Colucci Regulation of calcium channel expression in neonatal myocytes by catecholamines J. Clin. Invest. 97 1996 656 663
33. v1.2) and antagonizes channel phosphorylation by cAMP-dependent protein kinase J. Biol. Chem. 275 2000 39710 39717
34. T.J. Kamp, and J.W. Hell Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C Circ. Res. 87 2000 1095 1102
35. 2+ current in cardiac myocytes Pflügers Arch. 423 1993 245 250
36. Reuter H, Effects of neurotransmitters on the slow inward current. In: DP Zipes, JC Bailey, V Elharrar, editors. The slow inward current and cardiac arrhythmias. The Hague/Boston/London: Martinus Nijhoff Publishers; 1980. p. 205-19.
37. Carmeliet E, Electrophysiological effects of catecholamines in the heart. In: RA Riemersma, MF Oliver, editors. Catecholamines in the non-ischemic and ischemic myocardium. Amsterdam/New York/Oxford: Elsevier/North Holland biomedical press; 1982. p.77-86.
38. 2 adrenoceptor stimulation on potentials and contractions in the rabbit heart J. Physiol. (Lond.) 355 1984 523 546
39. 1-receptors in the mammalian heart J. Mol. Cell. Cardiol. 17 1985 639 645
40. H.C. Hartzell Regulation of cardiac ion channels by catecholamines, acetylcholine and second messenger systems Prog. Biophys. Mol. Biol. 52 1988 165 247
41. A. Zaza, R.P. Kline, and M.R. Rosen Effects of α-adrenergic stimulation on intracellular sodium activity and automaticity in canine Purkinje fibers Circ. Res. 66 1990 416 426
42. S.J. Liu, and R.H. Kennedy α1-Adrenergic activation of L-type Ca current in rat ventricular myocytes: perforated patch-clamp recordings Am. J. Physiol. 274 1998 H2203 H2207
43. Q.-Y. Liu, E. Karpinski, and P.K.T. Pang The L-type calcium channel current is increased by alpha-1 adrenoceptor activation in neonatal rat ventricular cells J. Pharmacol. Exp. Ther. 271 1994 935 943
44. 1- adrenergic-induced hypertrophy Am. J. Physiol. Heart Circ. Physiol. 44 1998 H577 H590
45. A. Yatani, J. Codina, Y. Imoto, J.P. Reeves, L. Birnbaumer, and A.M. Brown A G protein directly regulates mammalian cardiac calcium channels Science 238 1987 1288 1292
46. H.J. Yu, H. Ma, and R.D. Green Calcium entry via L-type calcium channels acts as a negative regulator of adenylyl cyclase activity and cyclic AMP levels in cardiac myocytes Mol. Pharmacol. 44 1993 689 693
47. ++ current in cardiac myocytes J. Pharmacol. Exp. Ther. 283 1997 452 461
48. 2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes Am. Soc. Pharmacol. Exp. Ther. 47 1995 322 329
49. 2- adrenergic modulation of cardiac excitation-contraction coupling Am. J. Physiol. Heart Circ. Physiol. 42 1997 H1611 H1618
50. 2 receptor subtype and evidence for PKA-independent activation of the channel Cell Signal. 11 1999 337 342
51. C. Communal, K. Singh, D.R. Pimentel, and W.S. Colucci Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway Circulation 98 1998 1329 1334
52. 2+ current in the early stages of cardiomyocyte development Circ. Res. 84 1999 136 145
53. 2+ channel currents in early-stage embryonic mouse heart Am. J. Physiol. 276 1999 H608 H613
54. T. Gao, T.S. Puri, B.L. Gerhardstein, A.J. Chien, R.D. Green, and M.M. Hosey Identification and subcellular localization of the subunits of L-type calcium channels and adenylyl cyclase in cardiac myocytes J. Biol. Chem. 272 1997 19401 19407
55. 2-Adrenergic receptor signalling complexes in cardiomyocyte caveolae/lipid rafts J. Mol. Cell. Cardiol. 37 2004 407 415
56. C. Schwenke, M. Yamamoto, S. Okumura, Y. Toya, S.-J. Kim, and Y. Ishikawa Compartmentation of cyclic adenosine 3′,5′-monophosphate signalling in caveolae Mol. Endocrinol. 13 1999 1061 1070
57. S.F. Steinberg, and L.L. Brunton Compartmentation of G-protein-coupled signalling pathways in cardiac myocytes Annu. Rev. Pharmacol. Toxicol. 41 2001 751 773
58. 2+ channel FEBS Lett. 309 1992 343 349
59. 1 subunit of the cardiac L-type calcium channel by adenosine 3′,5′-cyclic monophosphate-dependent protein kinase Biochemistry 35 1996 10392 10402
60. 2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits Neuron 19 1997 185 195
61. 2 subunit J. Biol. Chem. 274 1999 33851 33854
62. 1C subunit of L-type calcium channels and the role of a proline-rich domain in membrane tethering of proteolytic fragments J. Biol. Chem. 275 2000 8556 8563
63. 1c subunits J. Biol. Chem. 276 2001 21089 21097
64. 1 subunit of the L-type calcium channel: importance of the C-terminus Mol. Cell. Biochem. 250 2003 81 89
65. 1C subunit FEBS Lett. 384 1996 189 192
66. 2+ channels J. Physiol. (Lond.) 484 1995 583 592
67. - currents in guinea pig ventricular myocytes Mol. Pharmacol. 52 1997 725 734
68. H. Haase, P. Karczewski, R. Beckert, and E.G. Krause Phosphorylation of the L-type calcium channel β subunit is involved in β-adrenergic signal transduction in canine myocardium FEBS Lett. 335 1993 217 222
69. 2 subunit of L-type voltage-dependent calcium channels Biochemistry 38 1999 10361 10370
70. 1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15 Proc. Natl. Acad. Sci. U. S. A. 100 2003 13093 13098
71. H. Haase, T. Podzuweit, G. Lutsch, A. Hohaus, S. Kostka, and C. Lindschau Signaling from β-adrenoceptor to L-type calcium channel: identification of a novel cardiac protein kinase A target possessing similarities to AHNAK FASEB J. 13 1999 2161 2172
72. J. Alvarez, J. Hamplova, A. Hohaus, I. Morano, H. Haase, and G. Vassort Calcium current in rat cardiomyocytes is modulated by the carboxyl-terminal Ahnak domain J. Biol. Chem. 279 2004 12456 12461
73. 2+ channels is upregulated by Protein Kinase C J. Biol. Chem. 277 2002 3419 3423
74. v1.2 Biochem. Biophys. Res. Commun. 296 2002 429 433
75. v1.2 L-type calcium channel different from the principle heart form Biochem. Biophys. Res. Commun. 302 2003 23 28
76. v1.2 isoforms under the control of distinct 5′ flanking regulatory elements FEBS Lett. 546 2003 349 354
77. 2+ channel and its modulation by protein kinase C J. Biol. Chem. 273 1998 17901 17909
78. D. McHugh, E.M. Sharp, T. Scheuer, and W.A. Catterall Inhibition of cardiac L-type calcium channels by protein kinase C phosphorylation of two sites in the N-terminal domain Proc. Natl. Acad. Sci. U. S. A. 97 2000 12334 12338
79. 1C subunit J. Biol. Chem. 274 1999 31145 31149
80. G. Klein, H. Drexler, and F. Schröder Protein kinase G reverses all isoproterenol induced changes of cardiac single L-type calcium channel gating Cardiovasc. Res. 48 2000 367 374
81. R. Kumar, T. Namiki, and R.W. Joyner Effects of cGMP on L-type calcium current of adult and newborn rabbit ventricular cells Cardiovasc. Res. 33 1997 573 582
82. 2+ current to nitric oxide in frog ventricular myocytes J. Physiol. 534 2001 109 121
83. C. Sims, J. Chiu, and R.D. Harvey Tyrosine phosphatase inhibitors selectively antagonize β-adrenergic receptor-dependend regulation of cardiac ion channels Mol. Pharmacol. 58 2000 1213 1221
84. 2+ current cooperatively in human atrial myocytes Am. J. Physiol. Heart Circ. Physiol. 278 2000 H670 H676
85. 2+ current in guinea pig ventricular myocytes treated with modulators of tyrosine phosphorylation Am. J. Physiol. Heart Circ. Physiol. 45 1999 H1724 H1733
86. A.E. Belevych, S. Warriers, and R.D. Harvey Genistein inhibits cardiac L-type Ca(2+) channel activity by a tyrosine kinase-independent mechanism Mol. Pharmacol. 62 2002 554 565
87. A. Mikami, K. Imoto, T. Tanabe, T. Niidome, Y. Mori, and H. Takeshima Primary structure and functional expression of the cardiac dihydropyridine- sensitive calcium channel Nature 340 1989 230 233
88. R.B. Pearson, and B.E. Kemp Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations Methods Enzymol. 200 1991 62 81
89. P.J. Kennelly, and E.G. Krebs Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases J. Biol. Chem. 266 1991 15555 15558