Chronic verapamil treatment remodels ICa,L in mouse ventricle

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 292, Issue 4, 2007, Pages

  Schroder, Elizabeth ^a   Magyar, Janos ^a   Burgess, Don ^b   Andres, Douglas ^a   Satin, Jonathan ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b Asbury College   (United States)

Author keywords

Calcium channel blockade; Electrocardiogram; Electrophysiology; Ventricle

Indexed keywords

CALCIUM CHANNEL L TYPE; ISOPRENALINE; VERAPAMIL;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HEART MUSCLE CELL; HEART RATE; HOMEOSTASIS; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; WESTERN BLOTTING;

ACTION POTENTIALS; ADRENERGIC BETA-AGONISTS; ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; ELECTROCARDIOGRAPHY; FEMALE; GENE EXPRESSION; HEART; ISOPROTERENOL; MALE; MICE; MICE, INBRED ICR; MYOCYTES, CARDIAC; RNA, MESSENGER; VERAPAMIL;

EID: 34147131097     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00793.2006     Document Type: Article

References (48)

1. Antzelevich C, Fish J. Electrical heterogeneity within the ventricular wall. Basic Res Cardiol 96: 517-527, 2001.
2. 2+ channel expression at the cell surface by the small G-protein kir/Gem. Nature 411: 701-706, 2001.
3. Boknik P, Fockenbrock M, Herzig S, Knapp J, Linck B, Luss H, Muller FU, Muller T, Schmitz W, Schroder F, Neumann J. Protein phosphatase activity is increased in a rat model of long-term β-adrenergic stimulation. Naunyn Schmiedebergs Arch Pharmacol 362: 222-231, 2000.
4. Brice N, Berrow N, Campbell V, Page K, Brickley K, Tedder I, Dolphin A. Importance of the different beta subunits in the membrane expression of the alpha1A and alpha2 calcium channel subunits: studies using a depolarization-sensitive alpha1A and alpha2 calcium channel. Eur J Neurosci 9: 749-759, 1997.
5. Castellano A, Wei X, Birnbaumer L, Perez-Reyes E. Cloning and expression of a neuronal calcium channel beta subunit. J Biol Chem 268: 12359-12366, 1993.
6. 2+ channel diversity. Annu Rev Neurosci 16: 521-555, 2000.
7. 3-adrenergic receptor in the failing canine myocardium. Circ Res 89: 599-606, 2001.
8. 2+ channels. J Biol Chem 270: 30036-30044, 1995.
9. Chu V, Otero JM, Lopez O, Morgan JP, Amende I, Hampton TG. Method for non-invasively recording electrocardiograms in conscious mice. BMC Physiol 1: 6, 2001.
10. Clark EB, Hu N, Turner DR, Litter JE, Hansen J. Effect of chronic verapamil treatment on ventricular function and growth in chick embryos. Am J Physiol Heart Circ Physiol 261: H166-H171, 1991.
11. 2+ channel beta subunits revealed by their expression in adult rat heart cells. J Physiol 541: 435-452, 2002.
12. Colucci W, Sawyer D, Singh K, Communal C. Adrenergic overload and apoptosis in heart failure: implications for therapy. J Card Fail 6: 1-7, 2000.
13. Crump SM, Correll RN, Schroder EA, Lester WC, Finlin BS, Andres DA, Satin J. The L-type calcium channel α-subunit and protein kinase inhibitors modulate Rem-mediated regulation of current. Am J Physiol Heart Circ Physiol 291: H1959-H1971, 2006.
14. Danik S, Cabo C, Chiello C, Kang S, Wit AL, Coromilas J. Correlation of repolarization of ventricular monophasic action potential with ECG in the murine heart. Am J Physiol Heart Circ Physiol 283: H372-H381, 2002.
15. Demolombe S, Marionneau C, Le Bouter S, Charpentier F, Escande D. Functional genomics of cardiac ion channel genes. Cardiovasc Res 67: 438-447, 2005.
16. Fan IQ, Chen B, Marsh JD. Transcriptional regulation of L-type calcium channel expression in cardiac myocytes. J Mol Cell Cardiol 32: 1841-1849, 2000.
17. Fares N, Gomez JP, Potreau D. T-type calcium current is expressed in dedifferentiated adult rat ventricular cells in primary culture. CR Acad Sci III 319: 569-576, 1996.
18. Finlin B, Andres D. Rem is a new member of the Rad- and Gem/Kir Ras-related GTP-binding protein family repressed by lipopolysaccharide stimulation. J Biol Chem 272: 21982-21988, 1997.
19. Finlin BS, Crump SM, Satin J, Andres DA. Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases. Proc Natl Acad Sci USA 100: 14469-14474, 2003.
20. Gaborit N, Steenman M, Lamirault G, Le Meur N, Le Bouter S, Lande G, Leger J, Charpentier F, Christ T, Dobrev D, Escande D, Nattel S, Demolombe S. Human atrial ion channel and transporter subunit gene expression remodeling associated with valvular heart disease and atrial fibrillation. Circulation 112: 471-481, 2005.
21. Gao T, Chien A, Hosey M. Complexes of the alpha 1C and beta subunits generate the necessary signal for membrane targeting of class C L-type calcium channels. J Biol Chem 274: 2137-2144, 1999.
22. Girvin BG, Johnston GD. Comparison of the effects of a 7-day period of non-compliance on blood pressure control using three different antihypertensive agents. J Hypertens 22: 1409-1414, 2004.
23. Golden K, Ren J, Dean A, Marsh JD. Norepinephrine regulates the in vivo expression of the L-type calcium channel. Mol Cell Biochem 236: 107-114, 2002.
24. to,s: early afterdepolarizations, atrioventricular block, and ventricular arrhythmias in mice lacking Kv1.4 and expressing a dominant-negative Kv4 α subunit. Circ Res 87: 73-79, 2000.
25. 2+ channel alpha 2 delta subunit in current stimulation and subunit interaction. Neuron 16: 431-440, 1996.
26. 2+ channel diversity. Annu Rev Neurosci 17: 399-418, 1994.
27. Johnson BD, Zheng W, Korach KS, Scheuer T, Catterall WA, Rubanyi GM. Increased expression of the cardiac L-type calcium channel in estrogen receptor-deficient mice. J Gen Physiol 110: 135-140, 1997.
28. Jones L, Wei S, Yue D. Mechanism of auxiliary subunit modulation of neuronal alpha1E calcium channels. J Gen Physiol 112: 125-143, 1998.
29. 2+ channel. Nature 352: 527-530, 1991.
30. Leone M, Albanese J, Martin C. Positive inotropic stimulation. Curr Opin Crit Care 8: 395-403, 2002.
31. 2+ channel gamma subunit. Nat Genet 19: 340-347, 1998.
32. Lipsitz LA, Gagnon M, Vyas M, Iloputaife I, Kiely DK, Sorond F, Serrador J, Cheng DM, Babikian V, Cupples LA. Antihypertensive therapy increases cerebral blood flow and carotid distensibility in hypertensive elderly subjects. Hypertension 45: 216-221, 2005.
33. London GM, Guerin AP. Influence of arterial pulse and reflected waves on blood pressure and cardiac function. Am Heart J 138: 220-224, 1999.
34. Mandarim-de-Lacerda CA, Meirelles Pereira LM. Volume-weighted mean nuclear volume and numerical nuclear density in the cardiomyocyte following enalapril and verapamil treatment. Virchows Arch 438: 92-95, 2001.
35. Mitchell G, Andreas J, Koren G. Measurement of heart rate and A-T interval in the conscious mouse. Am J Physiol Heart Circ Physiol 274: H747-H751, 1998.
36. Olcese R, Qin N, Schneider T, Neely A, Wei X, Stefani E, Birnbaumer L. The amino terminus of a calcium channel beta subunit sets rates of channel inactivation independently of the subunit's effect on activation. Neuron 13: 1433-1438, 1994.
37. Oldenburg O, Eggebrecht H, Herrmann J, Naber CK, Haude M, Erbel R, Baumgart D. Dose-dependent effects of intracoronary verapamil on systemic and coronary hemodynamics. Cardiovasc Drugs Therapy 14: 651-655, 2000.
38. Pavlovic K, Benc D, Kmezic-Grujin J, Stojiljkovic J, Cemerlic-Adic N, Miljkovic T, Mesaros P. Fosinopril and amlodipine in the treatment of isolated systolic hypertension. Med Pregl 57: 45-53, 2004.
39. Perez-Reyes E, Castellano A, Kim H, Bertrand P, Baggstrom E, Lacerda A, Wei X, Birnbaumer L. Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel. J Biol Chem 267: 1792-1797, 1992.
40. Post SR, Hammond HK, Insel PA. Adrenergic receptors and receptor signaling in heart failure. Annu Rev Pharmacol Toxicol 39: 343-360, 1999.
41. 2+ current in compensated hypertrophy and heart failure. Cardiovasc Res 37: 300-311, 1998.
42. v4.2N transgenic mice. Circulation 105: 1850-1856, 2002.
43. Schmieder R, Messerli F, Garavaglia G, Nunez B. Cardiovascular effects of verapamil in patients with essential hypertension. Circulation 75: 1030-1036, 1987.
44. Singer D, Biel M, Lotan I, Flockerzi V, Hofmann F, Dascal N. The roles of the subunits in the function of the calcium channel. Science 253: 1553-1557, 1991.
45. 2+ channel modulation by recombinant auxiliary β subunits expressed in young adult heart cells. Circ Res 86: 175-184, 2000.
46. 2+ exchanger in failing pig myocytes. Circ Res 92: 897-903, 2003.
47. Wickenden AD, Kaprielian R, Kassiri Z, Tsoporis JN, Tsushima R, Fishman GI, Backx PH. The role of action potential prolongation and altered intracellular calcium handling in the pathogenesis of heart failure. Cardiovasc Res 37: 312-323, 1997.
48. Yamaguchi H, Hara M, Strobeck M, Fukasawa K, Schwartz A, Varadi G. Multiple modulation pathways of calcium channel activity by a beta subunit. Direct evidence of beta subunit participation in membrane trafficking of the alpha1C subunit. J Biol Chem 273: 19348-19356, 1998.