Beta-2 adrenergic activation of L-type Ca++ current in cardiac myocytes

Journal of Pharmacology and Experimental Therapeutics

Volumn 283, Issue 2, 1997, Pages 452-461

  Skeberdis, V Arvydas ^a,b   Jurevičius, Jonas ^a,b   Fischmeister, Rodolphe ^a,c  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b LITHUANIAN UNIVERSITY OF HEALTH SCIENCES   (Lithuania)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ACETYLCHOLINE; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM ION; FORSKOLIN; ISOBUTYLMETHYLXANTHINE; ZINTEROL;

ADRENERGIC SYSTEM; ADULT; AGED; ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CONCENTRATION RESPONSE; DRUG EFFECT; FEMALE; FROG; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HUMAN; HUMAN CELL; ION CURRENT; MALE; MEMBRANE POTENTIAL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL;

ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; ADULT; AGED; ANIMALS; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; CYCLIC AMP; ETHANOLAMINES; FEMALE; HUMANS; MALE; MYOCARDIUM; PHOSPHORYLATION; RANA ESCULENTA; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-2;

EID: 0030809185     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. ALTSCHULD, R. A., STARLING, R. C., HAMLIN, R. L., BILLMAN, G. E., HENSLEY, J., CASTILLO, L., FERTEL, R. H., HOHL, C. M., ROBITAILLE, P. M. L., JONES, L. R., XIAO, R. P. AND LAKATTA, E. G.: Response of failing canine and human heart cells to β2-adrenergic stimulation. Circulation 92: 1612-1618, 1995.
2. ARGIBAY, J. A., FISCHMEISTER, R. AND HARTZELL, H. C.: Inactivation, reactivation and pacing dependence of calcium current in frog cardiocytes: Correlation with current density. J. Physiol. (Lond.) 401: 201-226, 1988.
3. BILSKI, A. J., HALLIDAY, S. E., FITZGERALD, J. D. AND WADE, J. L.: The pharmacology of a β2-selective adrenoceptor antagonist (ICI 118,551). J. Cardiovasc. Pharmacol. 5: 430-437, 1983.
4. BOREA, P. A., AMERINI, S., MASINI, I., CERBAI, E., LEDDA, F., MANTELLI, L., VARANI, K. AND MUGELLI, A.: β1-adrenoceptors and β2-adrenoceptors in sheep cardiac ventricular muscle. J. Mol. Cell. Cardiol. 24: 753-763, 1992.
5. BRISTOW, M. R., HERSHBERGER, R. E., PORT, J. D., MINOBE, W. AND RASMUSSEN, R.: β1-adrenergic and β2-adrenergic receptor-mediated adenylate cyclase stimulation in nonfailing and failing human ventricular myocardium. Mol. Pharmacol. 35: 295-303, 1989.
6. BRODDE, O. E.: β1-adrenoceptors and β2-adrenoceptors in the human heart-properties, function, and alterations in chronic heart failure. Pharmacol. Rev. 43: 203-242, 1997
7. BRODDE, O. E.: (1993). Beta-adrenoceptors in cardiac disease. Pharmacol. Ther. 60: 405-430, 1991.
8. BUXTON, I. L. O. AND BRUNTON, L. L.: Direct analysis of β-adrenergic receptor subtypes on intact adult ventricular myocytes of the rat. Circ. Res. 56: 126-132, 1985.
9. CARLSSON, E., DAHLÖF, C. G., HEDBERG, A., PERSSON, H. AND TANGSTRAND, B.: Differentiation of cardiac chronotropic and inotropic effects of β-adrenoceptor agonists. Naunyn-Schmied. Arch. Pharmacol. 300: 101-105, 1977.
10. CERBAI, E., GUERRA, L., VARANI, K., BARBIERI, M., BOREA, P. A. AND MUGELLI, A.: β-adrenoceptor subtypes in young and old rat ventricular myocytes: A combined patch-clamp and binding study. Br. J. Pharmacol. 116: 1835-1842, 1995.
11. CERBAI, E., MASINI, I. AND MUGELLI, A.: Electrophysiological characterisation of cardiac β2-adrenoceptors in sheep Purkinje fibers. J. Mol. Cell. Cardiol. 22: 859-870, 1990.
12. CUI, Y. N., SHEN, Y. T., KALTHOF, B., IWASE, M., SATO, N., UECHI, M., VATNER, S. F. AND VATNER, D. E.: Identification and functional role of β-adrenergic receptor subtypes in primate and rodent: In vivo versus isolated myocytes. J. Mol. Cell. Cardiol. 28, 1307-1317, 1996.
13. DEL MONTE, F. D., KAUMANN, J. A., POOLE-WILSON, P. A., WYNNE, D. G., PEPPER, J. AND HARDING, S. E.: Coexistence of functioning β1-and β2-adrenoceptors in single myocytes from human ventricle. Circulation 88: 854-863, 1993.
14. FISCHMEISTER, R. AND HARTZELL, H. C.: Mechanisms of action of acetylcholine on calcium current in single cells from frog ventricle. J. Physiol. (Lond.) 376: 183-202, 1986.
15. FISCHMEISTER, R. AND HARTZELL, H. C.: Cyclic guanosine 3′,5′-monophosphate regulates the calcium current in single cells from frog ventricle. J. Physiol. (Lond.) 387: 453-472, 1987.
16. FBACE, A. M., MÉRY, P.-F., FISCHMEISTER, R. AND HARTZELL, H. C.: Rate-limiting steps in the β-adrenergic stimulation of cardiac calcium current. J. Gen. Physiol. 101: 337-353, 1993.
17. FREISSMUTH, M., HAUSLEITHNER, V., NEES, S., BOCK, M. AND SCHUTZ, W.: Cardiac ventricular β2-adrenoceptors in guinea-pigs and rats are localised on the coronary endothelium. Naunyn-Schmied. Arch. Pharmacol. 334: 56-62, 1986.
18. S. Mol. Pharmacol. 41: 889-893, 1992.
19. HANCOCK, A. A.,. DELEAN, A. L. AND LEFKOWITZ, R. J.: Quantitative resolution of beta-adrenergic subtypes by selective ligand binding: application of a computerized model fitting technique. Mol. Pharmacol. 16: 1-9, 1979.
20. 2+ channels by G proteins: neither proven nor necessary. Trends Pharmacol. Sci. 13: 380-385, 1992.
21. nd messenger systems. Prog. Biophys. Mol. Biol. 52: 165-247, 1988.
22. HARTZELL, H. C., MÉRY, P. F., FISCHMEISTER, R. AND SZABO, G.: Sympathetic regulation of cardiac calcium current is due exclusively to cAMP-dependent phosphorylation. Nature 351: 573-576, 1991.
23. HEDBERG, A., MINNEMAN,. K. P. AND MOLINOFF, P. B.: Differential distribution of beta-1 and beta-2 adrenergic receptors in cat and guinea-pig heart. J. Pharmacol. Exp. Ther. 212: 503-508, 1980.
24. HIEBLE, J. P. AND RUFFOLO, R. R.: Subclassification of β-adrenoceptors. β-Adrenoceptors: Mol. Biol. Biochem. Pharmacol. 7: 1-25, 1991.
25. IHL-VAHL, R., ESCHENHAGEN, T., KÜBLER, W., MARQUETANT, R., NOSE, M., SCHMITZ, W., SCHOLZ, H. AND STRASSER, R. H.: Differential regulation of mRNA specific for β1-and β2-adrenergic receptors in human failing hearts. Evaluation of the absolute cardiac mRNA levels by two independent methods. J. Mol. Cell. Cardiol. 28: 1-10, 1996.
26. IIJIMA, T. AND TAIRA, N.: β2-Adrenoceptor-mediated increase in the slow inward calcium current in atrial cells. Eur. J. Pharmacol. 163: 357-360, 1989.
27. 2+ current by acting exclusively at a site proximal to adenylyl cyclase in frog cardiac myocytes. J. Physiol. (Lond.) 491: 669-675, 1996a.
28. 2+ channels by β-adrenergic agonists. Proc. Nat. Acad. Sci. U.S.A. 93: 295-299, 1996b.
29. KAUMANN, A. J., SANDERS, L., LYNHAM, J. A., BARTEL, S., KUSCHEL, M., KARCZEWSKI, P. AND KRAUSE, E. G.: β2-adrenoceptor activation by zinterol causes protein phosphorylation, contractile effects and relaxant effects through a cAMP pathway in human atrium. Mol. Cell. Biochem. 163-164: 113-123.
30. KIRSTEIN, M., RIVET-BASTIDE, M., HATEM, S., BÉNARDEAU, A., MERCADIER, J. J. AND FISCHMEISTER, R.: Nitric oxide regulates the calcium current in isolated human atrial myocytes. J. Clin. Invest. 95: 794-802, 1995.
31. KUZNETSOV, V., PAK, E., ROBINSON, R. B. AND STEINBERG, S. F.: β2-adrenergic receptor actions in neonatal and adult rat ventricular myocytes. Circ. Res. 76: 40-52, 1995.
32. LAU, Y. H., ROBINSON, R. B., ROSEN, M. R. AND BILEZIKIAN, J. P.: Subclassification of β-adrenergic receptors in cultured rat cardiac myoblasts and fibroblasts. Circ. Res. 47: 41-48, 1980.
33. LEMOINE, H. AND KAUMANN, A. J.: Regional differences of β1-adrenoceptor-mediated and β2-adrenoceptor-mediated functions in feline heart - A β2-adrenoceptor-mediated positive inotropic effect possibly unrelated to cyclic AMP. Naunyn-Schmied. Arch. Pharmacol. 344: 56-69, 1991.
34. LEVY, F. O., ZHU, X., KAUMANN, A. J. AND BIRNBAUMER, L.: Efficacy of beta(1)-adrenergic receptors is lower than that of beta(2)-adrenergic receptors. Proc. Nat. Acad. Sci. U.S.A. 90: 10798-10802, 1993.
35. + currents in frog cardiac myocytes. J. Gen. Physiol. 104: 941-959, 1994.
36. 2+ current response to rapid applications of β-adrenergic and dihydropyridine agonists. Naunyn-Schmied. Arch. Pharmacol. 348: 197-206, 1993.
37. MCDONALD, T. F., PELZER, S., TRAUTWEIN, W. AND PELZER, D. J.: Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells. Physiol. Rev. 74: 365-507, 1994.
38. MINNEMAN, K. P., HEGSTRAND, L. R. AND MOLINOFF, P. B.: The pharmacological specificity of β-1 and β-2 adrenergic receptors in rat heart and lung in vitro. Mol. Pharmacol. 16: 21-33, 1979.
39. MOLENAAR, P. AND SUMMERS, R. J.: Characterisation of Beta-1 and Beta-2 adrenoceptors in guinea-pig atrium. Functional and receptor binding studies. J. Pharmacol. Exp. Ther. 241: 1041-1047, 1987.
40. MURPHREE, S. S. AND SAFFITZ, J. E.: Delineation of the distribution of β-adrenergic receptor subtypes in canine myocardium. Circ. Res. 63: 117-125, 1988.
41. 2-selective adrenoceptor antagonist and can be used to characterize beta-adrenoceptor populations in tissues. Life Sci. 27: 671-677, 1980.
42. PUCÉAT, M., LECHÊANE, P., CLÉMENT, O., PÉLOSIN, J. M., VENTURA-CLAPIER, R. AND VASSORT, G.: Neurohormonal control of Ca sensitivity of myofilaments in single rat heart cells. Circ. Res. 67: 517-524, 1990.
43. ROBBERECHT, P., DELHAYE, M., TATON, G., DE NEEF, P., WAELBROECK, M., DE SMET, J. M., LECLERC, J. L., CHATELAIN, P. AND CHRISTOPHE, J.: The human heart β-adrenergic receptors. 1. Heterogeneity of the binding sites: presence of 50% β1-and 50% β2-adrenergic receptors. Mol. Pharmacol. 24: 169-173, 1983.
44. RÜCKER-MARTIN, C., HATEM, S., DUBUS, I, MACE, L., SAMUEL, J.-L. AND MERCADIER, J.-J.: Behaviour of human atrial myocytes in culture is donor age dependent. Neuromusc. Disord. 3: 385-390, 1993.
45. SKEBERDIS, A. V., JUREVIČIUS, J. AND FISCHMEISTEH, R.: Beta2-adrenergic activation of cardiac Ca current is due to cAMP-dependent phosphorylation in frog ventricle. J. Mol. Cell. Cardiol. 28: A245, 1996.
46. 2+ current in frog ventricular myocytes. Br. J. Pharmacol. 121: 1277-1286, 1997.
47. STILES, G. L., CARON, M. C. AND LEFKOWITZ, R. J.: β-adrenergic receptors: biochemical mechanisms of physiological regulation. Physiol. Rev. 64: 661-743, 1984.
48. TANAKA, H., CLARK, R. B. AND GILES, W. R.: Positive chronotropic responses of rabbit sino-atrial node cells to flash photolysis of caged isoproterenol and cyclic AMP. Proc. Roy. Soc. Lond. (Biology) 263: 241-248, 1996.
49. WAELBHOECK, M., TATON, G., DELHAYE, M., CHATELAIN, P., CAMUS, J. C., POCHET, R., LECLERC, J. L., DE SMET, J. M., ROBBERECHT, P. AND CHRISTOPHE, J.: The human heart β-adrenergic receptors. 2. Coupling of β2-adrenergic receptors with the adenylate system. Mol. Pharmacol. 24: 174-182, 1983.
50. WALSH, D. A., ANGELOS, K. L., VAN PATTEN, S. M., GLASS, D. B. AND GARETTO, L. P.: The inhibitor protein of the cAMP-dependent protein kinase. In Peptides and Protein Phosphorylation, ed. by B. E. Kemp, pp. 43-84, CRC Press, Boca Raton, FL, 1990.
51. - tricular cardiomyocytes. J. Physiol. (Lond.) 489: 50P-51P, 1995.
52. WHITE, M., RODEN, R., MINOBE, W., KHAN, M. F., LARRABEE, P., WOLLMERING, M., PORT, J. D., ANDERSON, F., CAMPBELL, D., FELDMAN, A. M. AND BRISTOW, M. R.: Age-related changes in β-adrenergic neuroeffector systems in the human heart. Circulation 90: 1225-1238, 1994.
53. XIAO, R. P. AND LAKATTA, E. G.: β1-adrenoceptor stimulation and β2-adrenoceptor stimulation differ in their effects on contraction, cytosolic Ca2+, and Ca2+ current in single rat ventricular cells. Circ. Res. 73: 286-300, 1993.
54. XIAO, R. P., HOHL, C., ALTSCHULD, R., JONES, L., LIVINGSTON, B., ZIMAN, B., TANTINI, B. AND LAKATTA, E. G.: Beta(2)-adrenergic receptor-stimulated increase in cAMP in rat heart cells is not coupled to changes in Ca2+ dynamics, contractility, or phospholamban phosphorylation. J. Biol. Chem. 269: 19151-19156, 1994.
55. XIAO, R. P., JI, X. W. AND LAKATTA, E. G.: Functional coupling of the β(2)-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes. Mol. Pharmacol. 47: 322-329, 1995.