Ahnak1 interaction is affected by phosphorylation of Ser-296 on Cavβ 2

Biochemical and Biophysical Research Communications

Volumn 421, Issue 2, 2012, Pages 184-189

  Pankonien, Ines ^a,b   Otto, Albrecht ^a   Dascal, Nathan ^c   Morano, Ingo ^a,b   Haase, Hannelore ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Ahnak; Cav 2; L type calcium channel; PKA phosphorylation; Protein protein interaction

Indexed keywords

BINDING PROTEIN; CALCIUM CHANNEL L TYPE; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUTAMIC ACID; GUANYLATE KINASE; MUTANT PROTEIN; PROTEIN AHNAK1; PROTEIN CAV1.2; PROTEIN CAVBETA2; PROTEIN HOOK; PROTEIN SH3; SERINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; HEART MUSCLE CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SURFACE PLASMON RESONANCE;

ANIMALS; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; MEMBRANE PROTEINS; MICE; MICE, INBRED STRAINS; MYOCYTES, CARDIAC; NEOPLASM PROTEINS; PHOSPHORYLATION; PROTEIN INTERACTION MAPS; PROTEIN STRUCTURE, TERTIARY; SERINE;

EID: 84860468788     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.03.132     Document Type: Article

References (34)

1. Bers D.M. Cardiac excitation-contraction coupling. Nature 2002, 415:198-205.
2. Catterall W.A. Structure and regulation of voltage-gated Ca2+ channels. Annu. Rev. Cell Dev. Biol. 2000, 16:521-555.
3. Buraei Z., Yang J. The β subunit of voltage-gated Ca2+ channels. Physiol. Rev. 2010, 90:1461-1506.
4. Chen Y.H., Li M.H., Zhang Y., He L.L., Yamada Y., Fitzmaurice A., Shen Y., Zhang H., Tong L., Yang J. Structural basis of the alpha1-beta subunit interaction of voltage-gated Ca2+ channels. Nature 2004, 429:675-680.
5. Miriyala J., Nguyen T., Yue D.T., Colecraft H.M. Role of CaVbeta subunits, and lack of functional reserve, in protein kinase A modulation of cardiac CaV1.2 channels. Circ. Res. 2008, 102:e54-64.
6. Reuter H., Cachelin A.B., De Peyer J.E., Kokubun S. Modulation of calcium channels in cultured cardiac cells by isoproterenol and 8-bromo-cAMP. Cold Spring Harb. Symp. Quant. Biol. 1983, 48(Pt 1):193-200.
7. Fuller M.D., Emrick M.A., Sadilek M., Scheuer T., Catterall W.A. Molecular mechanism of calcium channel regulation in the fight-or-flight response. Sci. Signal. 2010, 3:ra70.
8. Gao T., Cuadra A.E., Ma H., Bunemann M., Gerhardstein B.L., Cheng T., Eick R.T., Hosey M.M. C-terminal fragments of the alpha 1C (CaV1.2) subunit associate with and regulate L-type calcium channels containing C-terminal-truncated alpha 1C subunits. J. Biol. Chem. 2001, 276:21089-21097.
9. Ganesan A.N., Maack C., Johns D.C., Sidor A., O'Rourke B. Beta-adrenergic stimulation of L-type Ca2+ channels in cardiac myocytes requires the distal carboxyl terminus of alpha1C but not serine 1928. Circ. Res. 2006, 98:e11-18.
10. Gomez-Ospina N., Tsuruta F., Barreto-Chang O., Hu L., Dolmetsch R. The C terminus of the L-type voltage-gated calcium channel Ca(V)1.2 encodes a transcription factor. Cell 2006, 127:591-606.
11. Schroder E., Byse M., Satin J. L-type calcium channel C terminus autoregulates transcription. Circ. Res. 2009, 104:1373-1381.
12. Gerhardstein B.L., Puri T.S., Chien A.J., Hosey M.M. Identification of the sites phosphorylated by cyclic AMP-dependent protein kinase on the beta 2 subunit of L-type voltage-dependent calcium channels. Biochemistry 1999, 38:10361-10370.
13. Bunemann M., Gerhardstein B.L., Gao T., Hosey M.M. Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the beta(2) subunit. J. Biol. Chem. 1999, 274:33851-33854.
14. Nichols C.B., Rossow C.F., Navedo M.F., Westenbroek R.E., Catterall W.A., Santana L.F., McKnight G.S. Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels. Circ. Res. 2010, 107:747-756.
15. Hohaus A., Person V., Behlke J., Schaper J., Morano I., Haase H. The carboxyl-terminal region of ahnak provides a link between cardiac L-type Ca2+ channels and the actin-based cytoskeleton. FASEB J. 2002, 16:1205-1216.
16. Matza D., Flavell R.A. Roles of Ca(v) channels and AHNAK1 in T cells: the beauty and the beast. Immunol. Rev. 2009, 231:257-264.
17. Carlson S.S., Valdez G., Sanes J.R. Presynaptic calcium channels and alpha3-integrins are complexed with synaptic cleft laminins, cytoskeletal elements and active zone components. J. Neurochem. 2010, 115:654-666.
18. Haase H. Ahnak, a new player in beta-adrenergic regulation of the cardiac L-type Ca2+ channel. Cardiovasc. Res. 2007, 73:19-25.
19. Alvarez J., Hamplova J., Hohaus A., Morano I., Haase H., Vassort G. Calcium current in rat cardiomyocytes is modulated by the carboxyl-terminal ahnak domain. J. Biol. Chem. 2004, 279:12456-12461.
20. Haase H., Alvarez J., Petzhold D., Doller A., Behlke J., Erdmann J., Hetzer R., Regitz-Zagrosek V., Vassort G., Morano I. Ahnak is critical for cardiac Ca(V)1.2 calcium channel function and its beta-adrenergic regulation. FASEB J. 2005, 19:1969-1977.
21. Alvarez J.L., Petzhold D., Pankonien I., Behlke J., Kouno M., Vassort G., Morano I., Haase H. Ahnak1 modulates L-type Ca(2+) channel inactivation of rodent cardiomyocytes. Pflugers Arch. 2010, 460:719-730.
22. Pankonien I., Alvarez J.L., Doller A., Kohncke C., Rotte D., Regitz-Zagrosek V., Morano I., Haase H. Ahnak1 is a tuneable modulator of cardiac Ca(v)1.2 calcium channel activity. J. Muscle Res. Cell Motil. 2011.
23. Perkins D.N., Pappin D.J., Creasy D.M., Cottrell J.S. Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 1999, 20:3551-3567.
24. Zacharias U., Purfurst B., Schowel V., Morano I., Spuler S., Haase H. Ahnak1 abnormally localizes in muscular dystrophies and contributes to muscle vesicle release. J. Muscle Res. Cell Motil. 2011, 32:271-280.
25. Marg A., Haase H., Neumann T., Kouno M., Morano I. AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness. Biochem. Biophys. Res. Commun. 2010, 401:143-148.
26. Huang Y., Laval S.H., van Remoortere A., Baudier J., Benaud C., Anderson L.V., Straub V., Deelder A., Frants R.R., den Dunnen J.T., Bushby K., van der Maarel S.M. AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration. FASEB J. 2007, 21:732-742.
27. Rezvanpour A., Santamaria-Kisiel L., Shaw G.S. The S100A10-annexin A2 complex provides a novel asymmetric platform for membrane repair. J. Biol. Chem. 2011.
28. Benaud C., Gentil B.J., Assard N., Court M., Garin J., Delphin C., Baudier J. AHNAK interaction with the annexin 2/S100A10 complex regulates cell membrane cytoarchitecture. J. Cell Biol. 2004, 164:133-144.
29. Van Petegem F., Clark K.A., Chatelain F.C., Minor D.L. Structure of a complex between a voltage-gated calcium channel beta-subunit and an alpha-subunit domain. Nature 2004, 429:671-675.
30. De Waard M., Pragnell M., Campbell K.P. Ca2+ channel regulation by a conserved beta subunit domain. Neuron 1994, 13:495-503.
31. Colecraft H.M., Alseikhan B., Takahashi S.X., Chaudhuri D., Mittman S., Yegnasubramanian V., Alvania R.S., Johns D.C., Marban E., Yue D.T. Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells. J. Physiol. 2002, 541:435-452.
32. Dolphin A.C. Beta subunits of voltage-gated calcium channels. J. Bioenerg. Biomembr. 2003, 35:599-620.
33. Geib S., Sandoz G., Mabrouk K., Matavel A., Marchot P., Hoshi T., Villaz M., Ronjat M., Miquelis R., Leveque C., de Waard M. Use of a purified and functional recombinant calcium-channel beta4 subunit in surface-plasmon resonance studies. Biochem. J. 2002, 364:285-292.
34. Canti C., Davies A., Berrow N.S., Butcher A.J., Page K.M., Dolphin A.C. Evidence for two concentration-dependent processes for beta-subunit effects on alpha1B calcium channels. Biophys. J. 2001, 81:1439-1451.