Spontaneous loss of tolerance of autoreactive B cells in Act1-deficient rheumatoid factor transgenic mice

Journal of Immunology

Volumn 191, Issue 5, 2013, Pages 2155-2163

  Giltiay, Natalia V ^a,c   Lu, Yi ^a   Cullen, Jaime L ^b   Jørgensen, Trine N ^a   Shlomchik, Mark J ^b   Li, Xiaoxia ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; B CELL ACTIVATING FACTOR RECEPTOR; CD40 ANTIGEN; CD40 LIGAND; CELL PROTEIN; PROTEIN ACT1; RHEUMATOID FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE ACTIVATION; B LYMPHOCYTE DIFFERENTIATION; CELL EXPANSION; CERVICAL LYMPH NODE; CONTROLLED STUDY; FLOW CYTOMETRY; GERMINAL CENTER; IMMUNOGLOBULIN PRODUCING CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SIGNAL TRANSDUCTION; SPLEEN; TRANSGENIC MOUSE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIBODY FORMATION; AUTOANTIBODIES; AUTOIMMUNITY; B-CELL ACTIVATING FACTOR; B-LYMPHOCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; RHEUMATOID FACTOR; SELF TOLERANCE;

EID: 84883384584     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1300152     Document Type: Article

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