메뉴 건너뛰기




Volumn 10, Issue 4, 1998, Pages 299-307

Positive and negative roles of the tyrosine kinase Lyn in B cell function

Author keywords

Autoimmunity; CD22; Fc RIIb; Lyn; Src family kinases

Indexed keywords

AUTOANTIBODY; CALCIUM; CD22 ANTIGEN; DNA ANTIBODY; IMMUNOGLOBULIN M; LYMPHOCYTE ANTIGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE;

EID: 0032147066     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1006/smim.1998.0122     Document Type: Article
Times cited : (81)

References (59)
  • 1
    • 0030584799 scopus 로고    scopus 로고
    • Tolerance sensitivity of immature-stage B cells. Can developmentally regulated B cell antigen receptor (BCR) signal transduction play a role?
    • 1. Monroe JG (1996) Tolerance sensitivity of immature-stage B cells. Can developmentally regulated B cell antigen receptor (BCR) signal transduction play a role? J Immunol 156:2657-2660
    • (1996) J Immunol , vol.156 , pp. 2657-2660
    • Monroe, J.G.1
  • 2
    • 0029965138 scopus 로고    scopus 로고
    • Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires
    • 2. Goodnow CC (1996) Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires. Proc Natl Acad Sci USA 93:2264-2271
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2264-2271
    • Goodnow, C.C.1
  • 5
    • 0024980981 scopus 로고
    • Antigen receptor tail clue
    • 5. Reth M (1989) Antigen receptor tail clue. Nature 338:383-384
    • (1989) Nature , vol.338 , pp. 383-384
    • Reth, M.1
  • 6
    • 0028926070 scopus 로고
    • Transmembrane signaling by antigen receptors of B and T lymphocytes
    • 6. DeFranco AL, (1995) Transmembrane signaling by antigen receptors of B and T lymphocytes. Curr Opin Cell Biol 7:163-175
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 163-175
    • DeFranco, A.L.1
  • 7
    • 0000387536 scopus 로고
    • B-cell antigen receptor motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn
    • 7. Law DA, Chan VWF, Datta SK, DeFranco AL (1993) B-cell antigen receptor motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn. Curr Biol 3:645-657
    • (1993) Curr Biol , vol.3 , pp. 645-657
    • Law, D.A.1    Chan, V.W.F.2    Datta, S.K.3    DeFranco, A.L.4
  • 8
    • 0028243540 scopus 로고
    • Role of tyrosine kinases in lymphocyte activation
    • 8. Sefton BM, Taddie JA (1994) Role of tyrosine kinases in lymphocyte activation. Curr Opin Immunol 6:372-379
    • (1994) Curr Opin Immunol , vol.6 , pp. 372-379
    • Sefton, B.M.1    Taddie, J.A.2
  • 9
    • 0031037993 scopus 로고    scopus 로고
    • B-cell antigen receptor-induced apoptosis requires both Ig alpha and Ig beta
    • 9. Tseng J, Eisfelder BJ, Clark MR (1997) B-cell antigen receptor-induced apoptosis requires both Ig alpha and Ig beta. Blood 89:1513-1520
    • (1997) Blood , vol.89 , pp. 1513-1520
    • Tseng, J.1    Eisfelder, B.J.2    Clark, M.R.3
  • 10
    • 0029864726 scopus 로고    scopus 로고
    • Cooperativity and segregation of function within the Ig-alpha/beta heterodimer of the B cell antigen receptor complex
    • 10. Luisiri P, Lee YJ, Eisfelder BJ, Clark MR (1996) Cooperativity and segregation of function within the Ig-alpha/beta heterodimer of the B cell antigen receptor complex. J Biol Chem 271:5158-5163
    • (1996) J Biol Chem , vol.271 , pp. 5158-5163
    • Luisiri, P.1    Lee, Y.J.2    Eisfelder, B.J.3    Clark, M.R.4
  • 11
    • 0028862078 scopus 로고
    • Role of B cell receptor Ig alpha and Ig beta subunits in MHC class II-restricted antigen presentation
    • 11. Bonnerot C, Lankar D, Hanau D, Spehner D, Davoust J, Salamero J, Fridman WH (1995) Role of B cell receptor Ig alpha and Ig beta subunits in MHC class II-restricted antigen presentation. Immunity 3:335-347
    • (1995) Immunity , vol.3 , pp. 335-347
    • Bonnerot, C.1    Lankar, D.2    Hanau, D.3    Spehner, D.4    Davoust, J.5    Salamero, J.6    Fridman, W.H.7
  • 12
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • 12. Weiss A, Littman DR (1994) Signal transduction by lymphocyte antigen receptors. Cell 76:263-274
    • (1994) Cell , vol.76 , pp. 263-274
    • Weiss, A.1    Littman, D.R.2
  • 13
    • 0029040199 scopus 로고
    • Protein tyrosine kinases in the initiation of antigen receptor signaling
    • 13. Bolen JB (1995) Protein tyrosine kinases in the initiation of antigen receptor signaling. Curr Opin Immunol 7:306-311
    • (1995) Curr Opin Immunol , vol.7 , pp. 306-311
    • Bolen, J.B.1
  • 14
    • 0028060150 scopus 로고
    • Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement
    • 14. Saouaf SJ, Mahajan S, Rowley RB, Kut SA, Fargnoli J, Burkhardt AL, Tsukada S, Witte ON, Bolen JB (1994) Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement. Proc Natl Acad Sci USA 91:9524-9528
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9524-9528
    • Saouaf, S.J.1    Mahajan, S.2    Rowley, R.B.3    Kut, S.A.4    Fargnoli, J.5    Burkhardt, A.L.6    Tsukada, S.7    Witte, O.N.8    Bolen, J.B.9
  • 15
    • 0028875162 scopus 로고
    • Recognition and specificity in protein tyrosine kinase-mediated signalling
    • 15. Songyang Z, Cantley L (1995) Recognition and specificity in protein tyrosine kinase-mediated signalling. Trend Biochem Sci 20:470-475
    • (1995) Trend Biochem Sci , vol.20 , pp. 470-475
    • Songyang, Z.1    Cantley, L.2
  • 16
    • 0030564833 scopus 로고    scopus 로고
    • Catalytic specificity of phosphotyrosine kinases Blk, Lyn, c-Src and Syk as assessed by phage display
    • 16. Schmitz R, Baumann G, Gram H (1996) Catalytic specificity of phosphotyrosine kinases Blk, Lyn, c-Src and Syk as assessed by phage display. J Mol Biol 260:664-677
    • (1996) J Mol Biol , vol.260 , pp. 664-677
    • Schmitz, R.1    Baumann, G.2    Gram, H.3
  • 18
    • 0030831199 scopus 로고    scopus 로고
    • The complexity of signaling pathways activated by the BCR
    • 18. DeFranco AL (1997) The complexity of signaling pathways activated by the BCR. Curr Opin Immunol 9:296-308
    • (1997) Curr Opin Immunol , vol.9 , pp. 296-308
    • DeFranco, A.L.1
  • 20
    • 0026350671 scopus 로고
    • Hematopoietic cells express two forms of lyn kinase differing by 21 amino acids in the amino terminus
    • 20. Yi TL, Bolen JB, Ihle JN (1991) Hematopoietic cells express two forms of lyn kinase differing by 21 amino acids in the amino terminus. Mol Cell Biol 11:2391-2398
    • (1991) Mol Cell Biol , vol.11 , pp. 2391-2398
    • Yi, T.L.1    Bolen, J.B.2    Ihle, J.N.3
  • 21
    • 0030740148 scopus 로고    scopus 로고
    • Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and downregulation
    • 21. Chan VWF, Meng F, Soriano P, DeFranco AL, Lowell CA (1997) Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and downregulation. Immunity 7:69-81
    • (1997) Immunity , vol.7 , pp. 69-81
    • Chan, V.W.F.1    Meng, F.2    Soriano, P.3    DeFranco, A.L.4    Lowell, C.A.5
  • 22
    • 0026593547 scopus 로고
    • Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signaling
    • 22. Yamanashi Y, Fukui Y, Wongsasant B, Kinoshita Y, Ichimori Y, Toyoshima K, Yamamoto T (1992) Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signaling. Proc Natl Acad Sci USA 89:1118-1122
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1118-1122
    • Yamanashi, Y.1    Fukui, Y.2    Wongsasant, B.3    Kinoshita, Y.4    Ichimori, Y.5    Toyoshima, K.6    Yamamoto, T.7
  • 26
    • 0027379716 scopus 로고
    • Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immune developmental intermediate in the production of long-lived marrow-derived B cells
    • 26. Allman DM, Ferguson SE, Lentz VM, Cancro MP (1993) Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immune developmental intermediate in the production of long-lived marrow-derived B cells. J Immunol 151:4431-4344
    • (1993) J Immunol , vol.151 , pp. 4431-14344
    • Allman, D.M.1    Ferguson, S.E.2    Lentz, V.M.3    Cancro, M.P.4
  • 27
    • 0030023652 scopus 로고    scopus 로고
    • Regulation of B lymphocyte negative and positive selection by tyrosine phosphatase CD45
    • 27. Cyster JG, Healy JI, Goodnow CC (1996) Regulation of B lymphocyte negative and positive selection by tyrosine phosphatase CD45. Nature 381:325-328
    • (1996) Nature , vol.381 , pp. 325-328
    • Cyster, J.G.1    Healy, J.I.2    Goodnow, C.C.3
  • 28
    • 0032492994 scopus 로고    scopus 로고
    • Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes
    • in press
    • 28. Chan VWF, Lowell CA, DeFranco AL (1998) Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes. Curr Biol 8:in press
    • (1998) Curr Biol , vol.8
    • Chan, V.W.F.1    Lowell, C.A.2    DeFranco, A.L.3
  • 30
    • 0029838991 scopus 로고    scopus 로고
    • Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice
    • 30. Wang J, Koizumi T, Watanabe T (1996) Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice. J Exp Med 184:831-838
    • (1996) J Exp Med , vol.184 , pp. 831-838
    • Wang, J.1    Koizumi, T.2    Watanabe, T.3
  • 32
    • 0030031886 scopus 로고    scopus 로고
    • Augmented humoral and anaphylactic responses in FcγRII-deficient mice
    • 32. Takai T, Ono M, Hikida M, Ohmori H, Ravetch JV (1996) Augmented humoral and anaphylactic responses in FcγRII-deficient mice. Nature 379:346-349
    • (1996) Nature , vol.379 , pp. 346-349
    • Takai, T.1    Ono, M.2    Hikida, M.3    Ohmori, H.4    Ravetch, J.V.5
  • 33
    • 0031033886 scopus 로고    scopus 로고
    • Co-ligation of the antigen and Fc receptors gives rise to the selective modulation of intracellular signaling in B cells. Regulation of the association of phosphatidylinositol 3-kinase and inositol 5′-phosphatase with the antigen receptor complex
    • 33. Kiener PA, Lioubin MN, Rohrschneider LR, Ledbetter JA, Nadler SG, Diegel ML (1997) Co-ligation of the antigen and Fc receptors gives rise to the selective modulation of intracellular signaling in B cells. Regulation of the association of phosphatidylinositol 3-kinase and inositol 5′-phosphatase with the antigen receptor complex. J Biol Chem 272:3838-3844
    • (1997) J Biol Chem , vol.272 , pp. 3838-3844
    • Kiener, P.A.1    Lioubin, M.N.2    Rohrschneider, L.R.3    Ledbetter, J.A.4    Nadler, S.G.5    Diegel, M.L.6
  • 35
    • 0031065146 scopus 로고    scopus 로고
    • Negative signaling in B cells causes reduced ras activity by reducing Shc-Grb2 interactions
    • 35. Tridandapani S, Chacko GW, Van Brocklyn JR, Coggeshall KM (1997) Negative signaling in B cells causes reduced Ras activity by reducing Shc-Grb2 interactions. J Immunol 158:1125-1132
    • (1997) J Immunol , vol.158 , pp. 1125-1132
    • Tridandapani, S.1    Chacko, G.W.2    Van Brocklyn, J.R.3    Coggeshall, K.M.4
  • 36
    • 0028932943 scopus 로고
    • Tyrosine phosphatases and the antibody response
    • 36. DeFranco AL, Law DA (1995) Tyrosine phosphatases and the antibody response. Science 268:263-264
    • (1995) Science , vol.268 , pp. 263-264
    • DeFranco, A.L.1    Law, D.A.2
  • 37
    • 0029835940 scopus 로고    scopus 로고
    • Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcγRIIB
    • 37. Ono M, Bolland S, Tempst P, Ravetch JV (1996) Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcγRIIB. Nature 383:263-266
    • (1996) Nature , vol.383 , pp. 263-266
    • Ono, M.1    Bolland, S.2    Tempst, P.3    Ravetch, J.V.4
  • 39
    • 0343307005 scopus 로고    scopus 로고
    • Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling
    • 39. Ono M, Okada H, Holland S, Yanagi S, Kurosaki T, Ravetch JV (1997) Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling. Cell 90:293-301
    • (1997) Cell , vol.90 , pp. 293-301
    • Ono, M.1    Okada, H.2    Holland, S.3    Yanagi, S.4    Kurosaki, T.5    Ravetch, J.V.6
  • 40
    • 0030792093 scopus 로고    scopus 로고
    • Protein-tyrosine phosphatase SHP-1 is dispensable for FcyRIIB-mediated inhibition of B cell antigen receptor activation
    • 40. Nadler MJS, Chen B, Anderson JS, Wortis HH, Neel BG (1997) Protein-tyrosine phosphatase SHP-1 is dispensable for FcyRIIB-mediated inhibition of B cell antigen receptor activation. J Biol Chem 272:20038-20043
    • (1997) J Biol Chem , vol.272 , pp. 20038-20043
    • Nadler, M.J.S.1    Chen, B.2    Anderson, J.S.3    Wortis, H.H.4    Neel, B.G.5
  • 41
    • 0030950344 scopus 로고    scopus 로고
    • Tuning antigen receptor signaling by CD22: Integrating cues from antigens and the microenvironment
    • 41. Cyster JG, Goodnow CC (1997) Tuning antigen receptor signaling by CD22: integrating cues from antigens and the microenvironment. Immunity 6:509-517
    • (1997) Immunity , vol.6 , pp. 509-517
    • Cyster, J.G.1    Goodnow, C.C.2
  • 42
    • 0029944192 scopus 로고    scopus 로고
    • Engagement of the adhesion receptor CD22 triggers a potent stimulatory signal for B cells and blocking CD22/CD22L interactions impairs T cell proliferation
    • 42. Tuscano J, Engel P, Tedder TF, Kehrl JH (1996) Engagement of the adhesion receptor CD22 triggers a potent stimulatory signal for B cells and blocking CD22/CD22L interactions impairs T cell proliferation. Blood 87:4723-4730
    • (1996) Blood , vol.87 , pp. 4723-4730
    • Tuscano, J.1    Engel, P.2    Tedder, T.F.3    Kehrl, J.H.4
  • 44
    • 0027175115 scopus 로고
    • Association of CD22 with the B cell antigen receptor
    • 44. Peaker CJ, Neuberger MS (1993) Association of CD22 with the B cell antigen receptor. Eur J Immunol 23:1358-1363
    • (1993) Eur J Immunol , vol.23 , pp. 1358-1363
    • Peaker, C.J.1    Neuberger, M.S.2
  • 46
    • 0030499431 scopus 로고    scopus 로고
    • CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-deficient mice
    • 46. Sato S, Miller AS, Inaoki M, Bock CB, Jansen PJ, Tang ML, Tedder TF (1996) CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity 5:551-562
    • (1996) Immunity , vol.5 , pp. 551-562
    • Sato, S.1    Miller, A.S.2    Inaoki, M.3    Bock, C.B.4    Jansen, P.J.5    Tang, M.L.6    Tedder, T.F.7
  • 49
    • 0030834178 scopus 로고    scopus 로고
    • Counterregulation by the coreceptors CD19 and CD22 of MAP kinase activation by membrane immunoglobulin
    • 49. Tooze RM, Doody GM, Fearon DT (1997) Counterregulation by the coreceptors CD19 and CD22 of MAP kinase activation by membrane immunoglobulin. Immunity 7:59-67
    • (1997) Immunity , vol.7 , pp. 59-67
    • Tooze, R.M.1    Doody, G.M.2    Fearon, D.T.3
  • 50
    • 0030047811 scopus 로고    scopus 로고
    • CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation
    • 50. Law CL, Sidorenko SP, Chandran KA, Zhao Z, Shen SH, Fischer EH, Clark EA (1996) CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation. J Exp Med 183:547-560
    • (1996) J Exp Med , vol.183 , pp. 547-560
    • Law, C.L.1    Sidorenko, S.P.2    Chandran, K.A.3    Zhao, Z.4    Shen, S.H.5    Fischer, E.H.6    Clark, E.A.7
  • 51
    • 0029048060 scopus 로고
    • Phosphotyrosine-dependent association between CD22 and the protein tyrosine phosphatase 1C
    • 51. Campbell MA, Klinman NR (1995) Phosphotyrosine-dependent association between CD22 and the protein tyrosine phosphatase 1C. Eur J Immunol 25:1573-1579
    • (1995) Eur J Immunol , vol.25 , pp. 1573-1579
    • Campbell, M.A.1    Klinman, N.R.2
  • 53
    • 0018249302 scopus 로고
    • Activation of mouse lymphocytes by anti-immunoglobulin. II. A thymus-independent response by a mature subset ofB lymphocytes
    • 53. Sieckmann DG, Scher I, Asofsky R, Mosier DE, Paul WE (1978) Activation of mouse lymphocytes by anti-immunoglobulin. II. A thymus-independent response by a mature subset ofB lymphocytes. J Exp Med 148:1628-1643
    • (1978) J Exp Med , vol.148 , pp. 1628-1643
    • Sieckmann, D.G.1    Scher, I.2    Asofsky, R.3    Mosier, D.E.4    Paul, W.E.5
  • 54
    • 0030993376 scopus 로고    scopus 로고
    • CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling
    • 54. Tedder TF, Tuscano J, Sato S, Kehrl JH (1997) CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling. Ann Rev Immunol 15:481-504
    • (1997) Ann Rev Immunol , vol.15 , pp. 481-504
    • Tedder, T.F.1    Tuscano, J.2    Sato, S.3    Kehrl, J.H.4
  • 56
    • 0030592564 scopus 로고    scopus 로고
    • Expansion or elimination of B cells in vivo: Dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor
    • 56. Rathmell JC, Townsend SE, Xu JC, Flavell RA, Goodnow CC (1996) Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell 87:319-329
    • (1996) Cell , vol.87 , pp. 319-329
    • Rathmell, J.C.1    Townsend, S.E.2    Xu, J.C.3    Flavell, R.A.4    Goodnow, C.C.5
  • 59
    • 0030586680 scopus 로고    scopus 로고
    • Signaling through CD38 augments B cell antigen receptor (BCR) responses and is dependent on BCR expression
    • 59. Lund FE, Yu N, Kim KM, Reth M, Howard MC (1996) Signaling through CD38 augments B cell antigen receptor (BCR) responses and is dependent on BCR expression. J Immunol 157:1455-1467
    • (1996) J Immunol , vol.157 , pp. 1455-1467
    • Lund, F.E.1    Yu, N.2    Kim, K.M.3    Reth, M.4    Howard, M.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.