Lack of T cells in Act1-deficient mice results in elevated IgM-specific autoantibodies but reduced lupus-like disease

European Journal of Immunology

Volumn 42, Issue 7, 2012, Pages 1695-1705

  Johnson, Angela C ^a   Davison, Laura M ^a   Giltiay, Natalia V ^a,b   Vareechon, Chairut ^a   Li, Xiaoxia ^a   Jørgensen, Trine N ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Autoantibodies; Autoimmunity; B cells; Systemic lupus erythematosus; T cells

Indexed keywords

ACT1 PROTEIN; ANTINUCLEAR ANTIBODY; CD40 LIGAND; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M ANTIBODY; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CONTROLLED STUDY; EPIGENETICS; FEMALE; GENE INTERACTION; GLOMERULITIS; HYPERGAMMAGLOBULINEMIA; KIDNEY; LUPUS LIKE SYNDROME; LYMPHADENOPATHY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SPLENOMEGALY; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIBODY SPECIFICITY; AUTOANTIBODIES; AUTOIMMUNITY; B-CELL ACTIVATING FACTOR; FEMALE; FLOW CYTOMETRY; IMMUNOGLOBULIN M; IMMUNOHISTOCHEMISTRY; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHATIC DISEASES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; SPLENOMEGALY; STATISTICS, NONPARAMETRIC; T-LYMPHOCYTES;

EID: 84863992023     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201142238     Document Type: Article

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