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Volumn 191, Issue 5, 2013, Pages 2731-2741

Differential roles of CXCL2 and CXCL3 and their receptors in regulating normal and asthmatic airway smooth muscle cell migration

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; CXCL3 CHEMOKINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 84883320616     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1203421     Document Type: Article
Times cited : (112)

References (74)
  • 6
    • 78651556965 scopus 로고    scopus 로고
    • Nogo-B regulates migration and contraction of airway smooth muscle cells by decreasing ARPC 2/3 and increasing MYL-9 expression
    • Xu, W., W. Hong, Y. Shao, Y. Ning, Z. Cai, and Q. Li. 2011. Nogo-B regulates migration and contraction of airway smooth muscle cells by decreasing ARPC 2/3 and increasing MYL-9 expression. Respir. Res. 12: 14.
    • (2011) Respir. Res. , vol.12 , pp. 14
    • Xu, W.1    Hong, W.2    Shao, Y.3    Ning, Y.4    Cai, Z.5    Li, Q.6
  • 10
    • 0037300601 scopus 로고    scopus 로고
    • The primary role in biologic activity of the neutrophil chemokines IL-8 and GRO-α in cultured nasal epithelial cells
    • Rudack, C., S. Maune, J. Eble, and J. M. Schroeder. 2003. The primary role in biologic activity of the neutrophil chemokines IL-8 and GRO-α in cultured nasal epithelial cells. J. Interferon Cytokine Res. 23: 113-123.
    • (2003) J. Interferon Cytokine Res. , vol.23 , pp. 113-123
    • Rudack, C.1    Maune, S.2    Eble, J.3    Schroeder, J.M.4
  • 11
    • 77953288700 scopus 로고    scopus 로고
    • Differential expression of the chemokines GRO-2, GRO-3, and interleukin-8 in colon cancer and their impact on metastatic disease and survival
    • Doll, D., L. Keller, M. Maak, A. L. Boulesteix, J. R. Siewert, B. Holzmann, and K. P. Janssen. 2010. Differential expression of the chemokines GRO-2, GRO-3, and interleukin-8 in colon cancer and their impact on metastatic disease and survival. Int. J. Colorectal Dis. 25: 573-581.
    • (2010) Int. J. Colorectal Dis. , vol.25 , pp. 573-581
    • Doll, D.1    Keller, L.2    Maak, M.3    Boulesteix, A.L.4    Siewert, J.R.5    Holzmann, B.6    Janssen, K.P.7
  • 12
    • 58149134863 scopus 로고    scopus 로고
    • CXC chemokines and their receptors: A case for a significant biological role in cutaneous wound healing
    • Zaja-Milatovic, S., and A. Richmond. 2008. CXC chemokines and their receptors: a case for a significant biological role in cutaneous wound healing. Histol. Histopathol. 23: 1399-1407.
    • (2008) Histol. Histopathol. , vol.23 , pp. 1399-1407
    • Zaja-Milatovic, S.1    Richmond, A.2
  • 14
    • 50649101494 scopus 로고    scopus 로고
    • Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages
    • Goleva, E., P. J. Hauk, C. F. Hall, A. H. Liu, D. W. Riches, R. J. Martin, and D. Y. Leung. 2008. Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages. J. Allergy Clin. Immunol. 122: 550-559.
    • (2008) J. Allergy Clin. Immunol. , vol.122 , pp. 550-559
    • Goleva, E.1    Hauk, P.J.2    Hall, C.F.3    Liu, A.H.4    Riches, D.W.5    Martin, R.J.6    Leung, D.Y.7
  • 16
    • 47749109823 scopus 로고    scopus 로고
    • The role of CXC chemokines and their receptors in cancer
    • Vandercappellen, J., J. Van Damme, and S. Struyf. 2008. The role of CXC chemokines and their receptors in cancer. Cancer Lett. 267: 226-244.
    • (2008) Cancer Lett. , vol.267 , pp. 226-244
    • Vandercappellen, J.1    Van Damme, J.2    Struyf, S.3
  • 17
    • 9444267059 scopus 로고    scopus 로고
    • The CXC chemokines growth-regulated oncogene (GRO) α, GROβ, GROγ, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor
    • Ahuja, S. K., and P. M. Murphy. 1996. The CXC chemokines growth-regulated oncogene (GRO) α, GROβ, GROγ, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor. J. Biol. Chem. 271: 20545-20550.
    • (1996) J. Biol. Chem. , vol.271 , pp. 20545-20550
    • Ahuja, S.K.1    Murphy, P.M.2
  • 18
    • 79952105905 scopus 로고    scopus 로고
    • Heterophilic chemokine receptor interactions in chemokine signaling and biology
    • Kramp, B. K., A. Sarabi, R. R. Koenen, and C. Weber. 2011. Heterophilic chemokine receptor interactions in chemokine signaling and biology. Exp. Cell Res. 317: 655-663.
    • (2011) Exp. Cell Res. , vol.317 , pp. 655-663
    • Kramp, B.K.1    Sarabi, A.2    Koenen, R.R.3    Weber, C.4
  • 23
    • 34548845557 scopus 로고    scopus 로고
    • Assays for in vitro monitoring of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cell migration
    • Goncharova, E. A., D. A. Goncharov, and V. P. Krymskaya. 2006. Assays for in vitro monitoring of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cell migration. Nat. Protoc. 1: 2933-2939.
    • (2006) Nat. Protoc. , vol.1 , pp. 2933-2939
    • Goncharova, E.A.1    Goncharov, D.A.2    Krymskaya, V.P.3
  • 24
    • 84866303876 scopus 로고    scopus 로고
    • STIM1 regulates platelet-derived growth factor-induced migration and Ca2+ influx in human airway smooth muscle cells
    • Suganuma, N., S. Ito, H. Aso, M. Kondo, M. Sato, M. Sokabe, and Y. Hasegawa. 2012. STIM1 regulates platelet-derived growth factor-induced migration and Ca2+ influx in human airway smooth muscle cells. PLoS ONE 7: e45056.
    • (2012) PLoS ONE , vol.7
    • Suganuma, N.1    Ito, S.2    Aso, H.3    Kondo, M.4    Sato, M.5    Sokabe, M.6    Hasegawa, Y.7
  • 28
    • 0035958732 scopus 로고    scopus 로고
    • Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway
    • Mody, N., J. Leitch, C. Armstrong, J. Dixon, and P. Cohen. 2001. Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway. FEBS Lett. 502: 21-24.
    • (2001) FEBS Lett. , vol.502 , pp. 21-24
    • Mody, N.1    Leitch, J.2    Armstrong, C.3    Dixon, J.4    Cohen, P.5
  • 30
    • 51649098950 scopus 로고    scopus 로고
    • The dual PI3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML
    • Kojima, K., M. Shimanuki, M. Shikami, I. J. Samudio, V. Ruvolo, P. Corn, N. Hanaoka, M. Konopleva, M. Andreeff, and H. Nakakuma. 2008. The dual PI3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML. Leukemia 22: 1728-1736.
    • (2008) Leukemia , vol.22 , pp. 1728-1736
    • Kojima, K.1    Shimanuki, M.2    Shikami, M.3    Samudio, I.J.4    Ruvolo, V.5    Corn, P.6    Hanaoka, N.7    Konopleva, M.8    Andreeff, M.9    Nakakuma, H.10
  • 31
    • 79959925819 scopus 로고    scopus 로고
    • Control of proliferation in astrocytoma cells by the receptor tyrosine kinase/PI3K/AKT signaling axis and the use of PI-103 and TCN as potential antiastrocytoma therapies
    • Gü rsel, D. B., Y. S. Connell-Albert, R. G. Tuskan, T. Anastassiadis, J. C. Walrath, J. J. Hawes, J. C. Amlin-Van Schaick, and K. M. Reilly. 2011. Control of proliferation in astrocytoma cells by the receptor tyrosine kinase/PI3K/AKT signaling axis and the use of PI-103 and TCN as potential antiastrocytoma therapies. Neuro-oncol. 13: 610-621.
    • (2011) Neuro-oncol. , vol.13 , pp. 610-621
    • Gürsel, D.B.1    Connell-Albert, Y.S.2    Tuskan, R.G.3    Anastassiadis, T.4    Walrath, J.C.5    Hawes, J.J.6    Amlin-Van Schaick, J.C.7    Reilly, K.M.8
  • 32
    • 0029914053 scopus 로고    scopus 로고
    • Immunotherapy suppresses the production of monocyte chemotactic and activating factor and augments the production of IL-8 in children with asthma
    • Hsieh, K. H., C. C. Chou, and B. L. Chiang. 1996. Immunotherapy suppresses the production of monocyte chemotactic and activating factor and augments the production of IL-8 in children with asthma. J. Allergy Clin. Immunol. 98: 580-587.
    • (1996) J. Allergy Clin. Immunol. , vol.98 , pp. 580-587
    • Hsieh, K.H.1    Chou, C.C.2    Chiang, B.L.3
  • 36
    • 24944580948 scopus 로고    scopus 로고
    • Chemokine response to febrile urinary tract infection
    • Otto, G., M. Burdick, R. Strieter, and G. Godaly. 2005. Chemokine response to febrile urinary tract infection. Kidney Int. 68: 62-70.
    • (2005) Kidney Int. , vol.68 , pp. 62-70
    • Otto, G.1    Burdick, M.2    Strieter, R.3    Godaly, G.4
  • 37
    • 70350461417 scopus 로고    scopus 로고
    • Critical role of the interleukin-17/interleukin-17 receptor axis in regulating host susceptibility to respiratory infection with Chlamydia species
    • Zhou, X., Q. Chen, J. Moore, J. K. Kolls, S. Halperin, and J.Wang. 2009. Critical role of the interleukin-17/interleukin-17 receptor axis in regulating host susceptibility to respiratory infection with Chlamydia species. Infect. Immun. 77: 5059-5070.
    • (2009) Infect. Immun. , vol.77 , pp. 5059-5070
    • Zhou, X.1    Chen, Q.2    Moore, J.3    Kolls, J.K.4    Halperin, S.5    Wang, J.6
  • 38
    • 84859745736 scopus 로고    scopus 로고
    • Platelet lysate from whole blood-derived pooled platelet concentrates and apheresisderived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: Production process, content and identification of active components
    • Fekete, N., M. Gadelorge, D. Fürst, C. Maurer, J. Dausend, S. Fleury-Cappellesso, V. Mailänder, R. Lotfi, A. Ignatius, L. Sensebé, et al. 2012. Platelet lysate from whole blood-derived pooled platelet concentrates and apheresisderived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identification of active components. Cytotherapy 14: 540-554.
    • (2012) Cytotherapy , vol.14 , pp. 540-554
    • Fekete, N.1    Gadelorge, M.2    Fürst, D.3    Maurer, C.4    Dausend, J.5    Fleury-Cappellesso, S.6    Mailänder, V.7    Lotfi, R.8    Ignatius, A.9    Sensebé, L.10
  • 39
    • 79955381192 scopus 로고    scopus 로고
    • PI-3K/AKT signal pathway modulates vascular smooth muscle cells migration under cyclic mechanical strain
    • Zhang, B. C., Z. W. Zhou, X. K. Li, and Y. W. Xu. 2011. PI-3K/AKT signal pathway modulates vascular smooth muscle cells migration under cyclic mechanical strain. Vasa 40: 109-116.
    • (2011) Vasa , vol.40 , pp. 109-116
    • Zhang, B.C.1    Zhou, Z.W.2    Li, X.K.3    Xu, Y.W.4
  • 40
    • 77649296147 scopus 로고    scopus 로고
    • Integrin-linked kinase functions as a downstream signal of platelet-derived growth factor to regulate actin polymerization and vascular smooth muscle cell migration
    • Esfandiarei, M., S. A. Yazdi, V. Gray, S. Dedhar, and C. van Breemen. 2010. Integrin-linked kinase functions as a downstream signal of platelet-derived growth factor to regulate actin polymerization and vascular smooth muscle cell migration. BMC Cell Biol. 11: 16.
    • (2010) BMC Cell Biol. , vol.11 , pp. 16
    • Esfandiarei, M.1    Yazdi, S.A.2    Gray, V.3    Dedhar, S.4    Van Breemen, C.5
  • 41
    • 68249150893 scopus 로고    scopus 로고
    • Adiponectin inhibits insulin-like growth factor-1-induced cell migration by the suppression of extracellular signal-regulated kinase 1/2 activation, but not Akt in vascular smooth muscle cells
    • Motobayashi, Y., Y. Izawa-Ishizawa, K. Ishizawa, S. Orino, K. Yamaguchi, K. Kawazoe, S. Hamano, K. Tsuchiya, S. Tomita, and T. Tamaki. 2009. Adiponectin inhibits insulin-like growth factor-1-induced cell migration by the suppression of extracellular signal-regulated kinase 1/2 activation, but not Akt in vascular smooth muscle cells. Hypertens. Res. 32: 188-193.
    • (2009) Hypertens. Res. , vol.32 , pp. 188-193
    • Motobayashi, Y.1    Izawa-Ishizawa, Y.2    Ishizawa, K.3    Orino, S.4    Yamaguchi, K.5    Kawazoe, K.6    Hamano, S.7    Tsuchiya, K.8    Tomita, S.9    Tamaki, T.10
  • 42
    • 0026514199 scopus 로고
    • Pathology of asthma
    • Jeffery, P. K. 1992. Pathology of asthma. Br. Med. Bull. 48: 23-39.
    • (1992) Br. Med. Bull. , vol.48 , pp. 23-39
    • Jeffery, P.K.1
  • 45
    • 84863815675 scopus 로고    scopus 로고
    • A novel adipocytokine, vaspin inhibits platelet-derived growth factor-BB-induced migration of vascular smooth muscle cells
    • Phalitakul, S., M. Okada, Y. Hara, and H. Yamawaki. 2012. A novel adipocytokine, vaspin inhibits platelet-derived growth factor-BB-induced migration of vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 423: 844-849.
    • (2012) Biochem. Biophys. Res. Commun. , vol.423 , pp. 844-849
    • Phalitakul, S.1    Okada, M.2    Hara, Y.3    Yamawaki, H.4
  • 46
    • 0032127522 scopus 로고    scopus 로고
    • Differential usage of the CXC chemokine receptors 1 and 2 by interleukin-8, granulocyte chemotactic protein-2 and epithelial-cell-derived neutrophil attractant-78
    • Wuyts, A., P. Proost, J. P. Lenaerts, A. Ben-Baruch, J. Van Damme, and J. M. Wang. 1998. Differential usage of the CXC chemokine receptors 1 and 2 by interleukin-8, granulocyte chemotactic protein-2 and epithelial-cell-derived neutrophil attractant-78. Eur. J. Biochem. 255: 67-73.
    • (1998) Eur. J. Biochem. , vol.255 , pp. 67-73
    • Wuyts, A.1    Proost, P.2    Lenaerts, J.P.3    Ben-Baruch, A.4    Van Damme, J.5    Wang, J.M.6
  • 48
    • 84862876092 scopus 로고    scopus 로고
    • Functional signaling biases in G protein-coupled receptors: Game theory and receptor dynamics
    • Maudsley, S., S. A. Patel, S. S. Park, L. M. Luttrell, and B. Martin. 2012. Functional signaling biases in G protein-coupled receptors: game theory and receptor dynamics. Mini Rev. Med. Chem. 12: 831-840.
    • (2012) Mini Rev. Med. Chem. , vol.12 , pp. 831-840
    • Maudsley, S.1    Patel, S.A.2    Park, S.S.3    Luttrell, L.M.4    Martin, B.5
  • 49
    • 84862905495 scopus 로고    scopus 로고
    • Functional selectivity in GPCR signaling: Understanding the full spectrum of receptor conformations
    • Goupil, E., S. A. Laporte, and T. E. Hébert. 2012. Functional selectivity in GPCR signaling: understanding the full spectrum of receptor conformations. Mini Rev. Med. Chem. 12: 817-830.
    • (2012) Mini Rev. Med. Chem. , vol.12 , pp. 817-830
    • Goupil, E.1    Laporte, S.A.2    Hébert, T.E.3
  • 50
    • 84862836529 scopus 로고    scopus 로고
    • Functional selectivity in GPCR heterocomplexes
    • González-Maeso, J., and S. C. Sealfon. 2012. Functional selectivity in GPCR heterocomplexes. Mini Rev. Med. Chem. 12: 851-855.
    • (2012) Mini Rev. Med. Chem. , vol.12 , pp. 851-855
    • González-Maeso, J.1    Sealfon, S.C.2
  • 52
    • 33745618476 scopus 로고    scopus 로고
    • Do biophysical properties of the airway smooth muscle in culture predict airway hyperresponsiveness?
    • An, S. S., B. Fabry, X. Trepat, N. Wang, and J. J. Fredberg. 2006. Do biophysical properties of the airway smooth muscle in culture predict airway hyperresponsiveness? Am. J. Respir. Cell Mol. Biol. 35: 55-64.
    • (2006) Am. J. Respir. Cell Mol. Biol. , vol.35 , pp. 55-64
    • An, S.S.1    Fabry, B.2    Trepat, X.3    Wang, N.4    Fredberg, J.J.5
  • 54
    • 33645827963 scopus 로고    scopus 로고
    • Inhibition of phosphoinositide 3-kinased attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model
    • Lee, K. S., H. K. Lee, J. S. Hayflick, Y. C. Lee, and K. D. Puri. 2006. Inhibition of phosphoinositide 3-kinased attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model. FASEB J. 20: 455-465.
    • (2006) FASEB J. , vol.20 , pp. 455-465
    • Lee, K.S.1    Lee, H.K.2    Hayflick, J.S.3    Lee, Y.C.4    Puri, K.D.5
  • 55
    • 84864260190 scopus 로고    scopus 로고
    • Corticosteroid insensitivity is reversed by formoterol via phosphoinositide-3-kinase inhibition
    • Rossios, C., Y. To, G. Osoata, M. Ito, P. J. Barnes, and K. Ito. 2012. Corticosteroid insensitivity is reversed by formoterol via phosphoinositide-3- kinase inhibition. Br. J. Pharmacol. 167: 775-786.
    • (2012) Br. J. Pharmacol. , vol.167 , pp. 775-786
    • Rossios, C.1    To, Y.2    Osoata, G.3    Ito, M.4    Barnes, P.J.5    Ito, K.6
  • 57
    • 80054736907 scopus 로고    scopus 로고
    • Structural basis for activation and inhibition of class I phosphoinositide 3-kinases
    • Vadas, O., J. E. Burke, X. Zhang, A. Berndt, and R. L. Williams. 2011. Structural basis for activation and inhibition of class I phosphoinositide 3-kinases. Sci. Signal. 4: re2.
    • (2011) Sci. Signal. , vol.4
    • Vadas, O.1    Burke, J.E.2    Zhang, X.3    Berndt, A.4    Williams, R.L.5
  • 60
    • 81855198898 scopus 로고    scopus 로고
    • Tangeretin, a citrus flavonoid, inhibits PGDF-BB-induced proliferation and migration of aortic smooth muscle cells by blocking AKT activation
    • Seo, J., H. S. Lee, S. Ryoo, J. H. Seo, B. S. Min, and J. H. Lee. 2011. Tangeretin, a citrus flavonoid, inhibits PGDF-BB-induced proliferation and migration of aortic smooth muscle cells by blocking AKT activation. Eur. J. Pharmacol. 673: 56-64.
    • (2011) Eur. J. Pharmacol. , vol.673 , pp. 56-64
    • Seo, J.1    Lee, H.S.2    Ryoo, S.3    Seo, J.H.4    Min, B.S.5    Lee, J.H.6
  • 61
    • 33749647713 scopus 로고    scopus 로고
    • Hyaluronan induces vascular smooth muscle cell migration through RHAMMmediated PI3K-dependent Rac activation
    • Gouëffic, Y., C. Guilluy, P. Guérin, P. Patra, P. Pacaud, and G. Loirand. 2006. Hyaluronan induces vascular smooth muscle cell migration through RHAMMmediated PI3K-dependent Rac activation. Cardiovasc. Res. 72: 339-348.
    • (2006) Cardiovasc. Res. , vol.72 , pp. 339-348
    • Gouëffic, Y.1    Guilluy, C.2    Guérin, P.3    Patra, P.4    Pacaud, P.5    Loirand, G.6
  • 62
    • 0033944872 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase and protein kinase C attenuates extracellular matrix protein-induced vascular smooth muscle cell chemotaxis
    • Willis, A. I., S. Fuse, X. J. Wang, E. Chen, G. P. Tuszynski, B. E. Sumpio, and V. Gahtan. 2000. Inhibition of phosphatidylinositol 3-kinase and protein kinase C attenuates extracellular matrix protein-induced vascular smooth muscle cell chemotaxis. J. Vasc. Surg. 31: 1160-1167.
    • (2000) J. Vasc. Surg. , vol.31 , pp. 1160-1167
    • Willis, A.I.1    Fuse, S.2    Wang, X.J.3    Chen, E.4    Tuszynski, G.P.5    Sumpio, B.E.6    Gahtan, V.7
  • 63
    • 84866077979 scopus 로고    scopus 로고
    • PI3K p110a isoform-dependent Rho GTPase Rac1 activation mediates H2S-promoted endothelial cell migration via actin cytoskeleton reorganization
    • Zhang, L. J., B. B. Tao, M. J. Wang, H. M. Jin, and Y. C. Zhu. 2012. PI3K p110a isoform-dependent Rho GTPase Rac1 activation mediates H2S-promoted endothelial cell migration via actin cytoskeleton reorganization. PLoS ONE 7: e44590.
    • (2012) PLoS ONE , vol.7
    • Zhang, L.J.1    Tao, B.B.2    Wang, M.J.3    Jin, H.M.4    Zhu, Y.C.5
  • 65
    • 77949429043 scopus 로고    scopus 로고
    • Gq-coupled purinergic receptors inhibit insulin-like growth factor-I/phosphoinositide 3-kinase pathway-dependent keratinocyte migration
    • Taboubi, S., F. Garrouste, F. Parat, G. Pommier, E. Faure, S. Monferran, H. Kovacic, and M. Lehmann. 2010. Gq-coupled purinergic receptors inhibit insulin-like growth factor-I/phosphoinositide 3-kinase pathway-dependent keratinocyte migration. Mol. Biol. Cell 21: 946-955.
    • (2010) Mol. Biol. Cell , vol.21 , pp. 946-955
    • Taboubi, S.1    Garrouste, F.2    Parat, F.3    Pommier, G.4    Faure, E.5    Monferran, S.6    Kovacic, H.7    Lehmann, M.8
  • 67
    • 67049137382 scopus 로고    scopus 로고
    • Isoform-selective phosphoinositide 3′-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: A novel therapeutic approach
    • Niedermeier, M., B. T. Hennessy, Z. A. Knight, M. Henneberg, J. Hu, A. V. Kurtova, W. G. Wierda, M. J. Keating, K. M. Shokat, and J. A. Burger. 2009. Isoform-selective phosphoinositide 3′-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach. Blood 113: 5549-5557.
    • (2009) Blood , vol.113 , pp. 5549-5557
    • Niedermeier, M.1    Hennessy, B.T.2    Knight, Z.A.3    Henneberg, M.4    Hu, J.5    Kurtova, A.V.6    Wierda, W.G.7    Keating, M.J.8    Shokat, K.M.9    Burger, J.A.10
  • 69
    • 33750285711 scopus 로고    scopus 로고
    • Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway
    • Meng, Q., C. Xia, J. Fang, Y. Rojanasakul, and B. H. Jiang. 2006. Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway. Cell. Signal. 18: 2262-2271.
    • (2006) Cell. Signal. , vol.18 , pp. 2262-2271
    • Meng, Q.1    Xia, C.2    Fang, J.3    Rojanasakul, Y.4    Jiang, B.H.5
  • 72
    • 77950243447 scopus 로고    scopus 로고
    • Drugging the PI3 kinome: From chemical tools to drugs in the clinic
    • Workman, P., P. A. Clarke, F. I. Raynaud, and R. L. van Montfort. 2010. Drugging the PI3 kinome: from chemical tools to drugs in the clinic. Cancer Res. 70: 2146-2157.
    • (2010) Cancer Res. , vol.70 , pp. 2146-2157
    • Workman, P.1    Clarke, P.A.2    Raynaud, F.I.3    Van Montfort, R.L.4
  • 74
    • 84864535429 scopus 로고    scopus 로고
    • Different PI 3-kinase inhibitors have distinct effects on endothelial permeability and leukocyte transmigration
    • Cain, R. J., B. Vanhaesebroeck, and A. J. Ridley. 2012. Different PI 3-kinase inhibitors have distinct effects on endothelial permeability and leukocyte transmigration. Int. J. Biochem. Cell Biol. 44: 1929-1936.
    • (2012) Int. J. Biochem. Cell Biol. , vol.44 , pp. 1929-1936
    • Cain, R.J.1    Vanhaesebroeck, B.2    Ridley, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.