Autocrine-regulated airway smooth muscle cell migration is dependent on IL-17-induced growth-related oncogenes

Journal of Allergy and Clinical Immunology

Volumn 130, Issue 4, 2012, Pages

  Al Alwan, Laila A ^a   Chang, Ying ^a   Baglole, Carolyn J ^a   Risse, Paul André ^a   Halayko, Andrew J ^b   Martin, James G ^a   Eidelman, David H ^a   Hamid, Qutayba ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Airway remodeling; Airway smooth muscle cells; Asthma; Growth related oncogenes; IL 17; Migration

Indexed keywords

CHEMOKINE RECEPTOR CXCR2; GROWTH RELATED ONCOGENE ALPHA; GROWTH RELATED ONCOGENE BETA; GROWTH RELATED ONCOGENE GAMMA; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; INTERLEUKIN 17F; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG;

AIRWAY REMODELING; AIRWAY SMOOTH MUSCLE CELL; ARTICLE; ASTHMA; AUTOCRINE EFFECT; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; PATHOGENESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER;

EID: 84869127960     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2012.04.042     Document Type: Article

References (52)

1. Munakata M. Airway remodeling and airway smooth muscle in asthma. Allergol Int 2006;55:235-43.
2. Vignola AM, Mirabella F, Costanzo G, Di Giorgi R, Gjomarkaj M, Bellia V, et al. Airway remodeling in asthma. Chest 2003;123(suppl):417S-22S.
3. Lazaar AL, Panettieri RA Jr. Airway smooth muscle: A modulator of airway remodeling in asthma. J Allergy Clin Immunol 2005;116:488-96.
4. Minshall EM, Leung DY, Martin RJ, Song YL, Cameron L, Ernst P, et al. Eosinophil- associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma. Am J Respir Cell Mol Biol 1997;17:326-33.
5. Hoshino M, Nakamura Y, Sim JJ. Expression of growth factors and remodeling of the airway wall in bronchial asthma. Thorax 1998;53:21-7.
6. Lambert RK,Wiggs BR, Kuwano K, Hogg JC, Pare PD. Functional significance of increased airway smooth muscle in asthma and COPD. JAppl Physiol 1993;74:2771-81.
7. Bentley JK, Hershenson MB. Airway smooth muscle growth in asthma: Proliferation, hypertrophy, and migration. Proc Am Thorac Soc 2008;5:89-96.
8. Black JL, Roth M, Lee J, Carlin S, Johnson PR. Mechanisms of airway remodeling. Airway smooth muscle. Am J Respir Crit Care Med 2001;164(suppl):S63- 6.
9. Ramos-Barbon D, Fraga-Iriso R, Brienza NS, Montero-Martinez C, Verea-Hernando H, Olivenstein R, et al. T Cells localize with proliferating smooth muscle alpha-actin1 cell compartments in asthma. Am J Respir Crit Care Med 2010; 182:317-24.
10. Fixman ED, Stewart A, Martin JG. Basic mechanisms of development of airway structural changes in asthma. Eur Respir J 2007;29:379-89.
11. Vignola AM, La Grutta S, Chiappara G, Benkeder A, BelliaV, Bonsignore G. Cellular network in airways inflammation and remodelling. Paediatr Respir Rev 2002;3:41-6.
12. Takeda N, Sumi Y, Prefontaine D, Al Abri J, Al Heialy N, Al-Ramli W, et al. Epithelium- derived chemokines induce airway smooth muscle cell migration. Clin Exp Allergy 2009;39:1018-26.
13. Kaur D, Saunders R, Berger P, Siddiqui S, Woodman L, Wardlaw A, et al. Airway smooth muscle and mast cell-derived CC chemokine ligand 19 mediate airway smooth muscle migration in asthma. Am J Respir Crit Care Med 2006;174: 1179-88.
14. Kuo PL, Hsu YL, Tsai MJ, Lien CT, Huang MS, Ko YC, et al. Nonylphenol induces bronchial epithelial apoptosis via Fas-mediated pathway and stimulates bronchial epithelium to secrete IL-6 and IL-8, causing bronchial smooth muscle proliferation and migration. Basic Clin Pharmacol Toxicol 2011;110:178-86.
15. Parameswaran K, Radford K, Fanat A, Stephen J, Bonnans C, Levy BD, et al. Modulation of human airway smooth muscle migration by lipid mediators and Th-2 cytokines. Am J Respir Cell Mol Biol 2007;37:240-7.
16. Xu W, Hong W, Shao Y, Ning Y, Cai Z, Li Q. Nogo-B regulates migration and contraction of airway smooth muscle cells by decreasing ARPC 2/3 and increasing MYL-9 expression. Respir Res 2011;12:14.
17. Prefontaine D, Lajoie-Kadoch S, Foley S, Audusseau S, Olivenstein R, Halayko AJ, et al. Increased expression of IL-33 in severe asthma: Evidence of expression by airway smooth muscle cells. J Immunol 2009;183:5094-103.
18. Clarke DL, Clifford RL, Jindarat S, Proud D, Pang L, Belvisi M, et al. TNFalpha and IFNgamma synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-kappaB, and the transcriptional coactivator CREB-binding protein. J Biol Chem 2010;285:29101-10.
19. Knobloch J, Peters H, Jungck D, Muller K, Strauch J, Koch A. TNFalpha-induced GM-CSF release from human airway smooth muscle cells depends on activation of an ET-1 autoregulatory positive feedback mechanism. Thorax 2009;64:1044-52.
20. Agache I, Ciobanu C, Agache C, Anghel M. Increased serum IL-17 is an independent risk factor for severe asthma. Respir Med 2010;104:1131-7.
21. Al-Ramli W, Prefontaine D, Chouiali F, Martin JG, Olivenstein R, Lemiere C, et al. T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma. J Allergy Clin Immunol 2009;123:1185-7.
22. Iwakura Y, Nakae S, Saijo S, Ishigame H. The roles of IL-17A in inflammatory immune responses and host defense against pathogens. Immunol Rev 2008;226: 57-79.
23. Doe C, Bafadhel M, Siddiqui S, Desai D, Mistry V, Rugman P, et al. Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD. Chest 2010;138:1140-7.
24. Chang Y, Al-Alwan L, Risse PA, Roussel L, Rousseau S, Halayko AJ, et al. TH17 cytokines induce human airway smooth muscle cell migration. J Allergy Clin Immunol 2011;127:1046-53, e1-2.
25. Wang Q, Li H, Yao Y, Xia D, Zhou J. The overexpression of heparin-binding epidermal growth factor is responsible for Th17-induced airway remodeling in an experimental asthma model. J Immunol 2010;185:834-41.
26. Olson TS, Ley K. Chemokines and chemokine receptors in leukocyte trafficking. Am J Physiol Regul Integr Comp Physiol 2002;283:R7-28.
27. Haskill S, Peace A, Morris J, Sporn SA, Anisowicz A, Lee SW, et al. Identification of three related human GRO genes encoding cytokine functions. Proc Natl Acad Sci U S A 1990;87:7732-6.
28. Rudack C, Maune S, Eble J, Schroeder JM. The primary role in biologic activity of the neutrophil chemokines IL-8 and GRO-alpha in cultured nasal epithelial cells. J Interferon Cytokine Res 2003;23:113-23.
29. Doll D, Keller L, Maak M, Boulesteix AL, Siewert JR, Holzmann B, et al. Differential expression of the chemokines GRO-2, GRO-3, and interleukin-8 in colon cancer and their impact on metastatic disease and survival. Int J Colorectal Dis 2010;25:573-81.
30. Zaja-Milatovic S, Richmond A. CXC chemokines and their receptors: A case for a significant biological role in cutaneous wound healing. Histol Histopathol 2008;23: 1399-407.
31. Goleva E, Hauk PJ, Hall CF, Liu AH, Riches DW, Martin RJ, et al. Corticosteroidresistant asthma is associated with classical antimicrobial activation of airway macrophages. J Allergy Clin Immunol 2008;122:550-9, e3.
32. Huang F, Kao CY, Wachi S, Thai P, Ryu J, Wu R. Requirement for both JAKmediated PI3K signaling and ACT1/TRAF6/TAK1-dependent NF-kappaB activation by IL-17A in enhancing cytokine expression in human airway epithelial cells. J Immunol 2007;179:6504-13.
33. Goncharova EA, Goncharov DA, Krymskaya VP. Assays for in vitro monitoring of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cell migration. Nat Protoc 2006;1:2933-9.
34. Bradley ME, Bond ME, Manini J, Brown Z, Charlton SJ. SB265610 is an allosteric, inverse agonist at the human CXCR2 receptor. Br J Pharmacol 2009;158: 328-38.
35. Rahman MS, Yamasaki A, Yang J, Shan L, Halayko AJ, Gounni AS. IL-17A induces eotaxin-1/CC chemokine ligand 11 expression in human airway smooth muscle cells: Role of MAPK (Erk1/2, JNK, and p38) pathways. J Immunol 2006; 177:4064-71.
36. Awane M, Andres PG, Li DJ, Reinecker HC. NF-kappa B-inducing kinase is a common mediator of IL-17-, TNF-alpha-, and IL-1 beta-induced chemokine promoter activation in intestinal epithelial cells. J Immunol 1999;162:5337-44.
37. Sebolt-Leopold JS, Dudley DT, Herrera R, Van Becelaere K, Wiland A, Gowan RC, et al. Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nat Med 1999;5:810-6.
38. Minamitani C, Otsuka T, Takai S, Matsushima-Nishiwaki R, Adachi S, Hanai Y, et al. Involvement of Rho-kinase in prostaglandin F2alpha-stimulated interleukin- 6 synthesis via p38 mitogen-activated protein kinase in osteoblasts. Mol Cell Endocrinol 2008;291:27-32.
39. Kelly E, Bailey CP, Henderson G. Agonist-selective mechanisms of GPCR desensitization. Br J Pharmacol 2008;153(suppl 1):S379-88.
40. Jarai G, Sukkar M, Garrett S, Duroudier N, Westwick J, Adcock I, et al. Effects of interleukin-1beta, interleukin-13 and transforming growth factor-beta on gene expression in human airway smooth muscle using gene microarrays. Eur J Pharmacol 2004;497:255-65.
41. Issa R, Xie S, Lee KY, Stanbridge RD, Bhavsar P, SukkarMB, et al. GRO-alpha regulation in airway smooth muscle by IL-1beta and TNF-alpha: Role of NF-kappaB and MAP kinases. Am J Physiol Lung Cell Mol Physiol 2006;291:L66-74.
42. Halayko AJ, Stephens NL. Potential role for phenotypic modulation of bronchial smooth muscle cells in chronic asthma. Can J Physiol Pharmacol 1994;72: 1448-57.
43. Carroll N, Carello S, Cooke C, James A. Airway structure and inflammatory cells in fatal attacks of asthma. Eur Respir J 1996;9:709-15.
44. Rahman MS, Yang J, Shan LY, Unruh H, Yang X, Halayko AJ, et al. IL-17R activation of human airway smooth muscle cells induces CXCL-8 production via a transcriptional-dependent mechanism. Clin Immunol 2005;115:268-76.
45. Wuyts WA, Vanaudenaerde BM, Dupont LJ, Van Raemdonck DE, Demedts MG, Verleden GM. Interleukin-17-induced interleukin-8 release in human airway smooth muscle cells: Role for mitogen-activated kinases and nuclear factor-kappaB. J Heart Lung Transplant 2005;24:875-81.
46. Henness S, van Thoor E, Ge Q, Armour CL, Hughes JM, Ammit AJ. IL-17A acts via p38 MAPK to increase stability of TNF-alpha-induced IL-8 mRNA in human ASM. Am J Physiol Lung Cell Mol Physiol 2006;290:L1283-90.
47. Robins S, Roussel L, Schachter A, Risse PA, Mogas AK, Olivenstein R, et al. Steroid- insensitive ERK1/2-activity drives CXCL8 synthesis and neutrophilia by airway smooth muscle. Am J Respir Cell Mol Biol 2011;45:984-90.
48. Onishi RM, Gaffen SL. Interleukin-17 and its target genes: Mechanisms of interleukin-17 function in disease. Immunology 2010;129:311-21.
49. Prause O, Laan M, Lotvall J, Linden A. Pharmacological modulation of interleukin-17-induced GCP-2-, GRO-alpha- and interleukin-8 release in human bronchial epithelial cells. Eur J Pharmacol 2003;462:193-8.
50. Gordon RJ, McGregor AL, Connor B. Chemokines direct neural progenitor cell migration following striatal cell loss. Mol Cell Neurosci 2009;41:219-32.
51. Ahuja SK, Murphy PM. The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cellderived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor. J Biol Chem 1996;271:20545-50.
52. Moran EM, Connolly M, Gao W, McCormick J, Fearon U, Veale DJ. Interleukin- 17A induces angiogenesis, cell migration, and cytoskeletal rearrangement. Arthritis Rheum 2011;63:3263-73.