The catalytic class IA PI3K isoforms play divergent roles in breast cancer cell migration

Cellular Signalling

Volumn 23, Issue 3, 2011, Pages 529-541

  De Laurentiis, Angela ^a   Pardo, Olivier E ^b   Palamidessi, Andrea ^c   Jackson, Shaun P ^d   Schoenwaelder, Simone M ^d   Reichmann, Ernst ^a   Scita, Giorgio ^c   Arcaro, Alexandre ^a  

^a UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^d MONASH UNIVERSITY   (Australia)

Author keywords

Akt; Breast cancer; Cell migration; Phosphoinositide 3 kinase

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE P100ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE P100BETA; PHOSPHATIDYLINOSITOL 3 KINASE P100DELTA; PROTEIN CDC42; PROTEIN KINASE B; RAC PROTEIN; RAS PROTEIN; S6 KINASE; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL; CATALYSIS; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FIBROBLAST; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BREAST NEOPLASMS; CELL LINE; CELL LINE, TRANSFORMED; CELL MOVEMENT; CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE; CYTOSKELETAL PROTEINS; CYTOSKELETON; DOWN-REGULATION; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENES, RAS; HUMANS; ISOENZYMES; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1; TUMOR CELLS, CULTURED;

EID: 78650417941     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2010.10.021     Document Type: Article

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