Per-Arnt-Sim kinase regulates pancreatic duodenal homeobox-1 protein stability via phosphorylation of glycogen synthase kinase 3β in pancreatic β-cells

Journal of Biological Chemistry

Volumn 288, Issue 34, 2013, Pages 24825-24833

  Semache, Meriem ^a,b   Zarrouki, Bader ^a,c   Fontés, Ghislaine ^a   Fogarty, Sarah ^d   Kikani, Chintan ^d   Chawki, Mohammad B ^a   Rutter, Jared ^d   Poitout, Vincent ^a,b,c  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Department of Biochemistry ^*  (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE-3; INSULIN GENE PROMOTER; INSULIN GENE TRANSCRIPTION; ISLETS OF LANGERHANS; PHOSPHORYLATION SITES; PROTEASOMAL DEGRADATION; PROTEIN EXPRESSIONS; SERINE PHOSPHORYLATION;

AMINO ACIDS; CELLS; CYTOLOGY; ENZYMES; GENES; GLUCOSE; INSULIN; PROTEINS; TRANSCRIPTION;

PHOSPHORYLATION;

GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; PER ARNT SIM KINASE; PROTEIN SERINE THREONINE KINASE; SERINE; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DUODENUM; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; INSULIN RELEASE; MALE; MOLECULAR MECHANICS; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN STABILITY; PROTEIN SYNTHESIS REGULATION; PROTEIN TARGETING;

Β-CELL; DIABETES; GLYCOGEN SYNTHASE KINASE 3; INSULIN; PANCREATIC DUODENAL HOMEOBOX-1; PANCREATIC ISLETS;

ANIMALS; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3; HEP G2 CELLS; HOMEODOMAIN PROTEINS; HUMANS; INSULIN-SECRETING CELLS; MALE; MICE; MUTATION; PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, WISTAR; SWEETENING AGENTS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

EID: 84883191685     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.495945     Document Type: Article

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