Human mutation within per-arnt-sim (PAS) domain-containing protein kinase (PASK) causes basal insulin hypersecretion

Journal of Biological Chemistry

Volumn 286, Issue 51, 2011, Pages 44005-44014

  Semplici, Francesca ^a   Vaxillaire, Martine ^c,d   Fogarty, Sarah ^e   Semache, Meriem ^f   Bonnefond, Amélie ^c,d   Fonte, Ghislaine ^f   Philippe, Julien ^c,d   Meur, Gargi ^a   Diraison, Frederique ^g   Sessions, Richard B ^h   Rutter, Jared ^e   Poitout, Vincent ^f,i   Froguel, Philippe ^b,c,d   Rutter, Guy A ^a  

^a Section of Cell Biology   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c INSTITUT PASTEUR DE LILLE   (France)

^d UNIV LILLE   (France)

^e UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^f CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^g UNIVERSITY OF THE WEST OF ENGLAND   (United Kingdom)

^h UNIVERSITY OF BRISTOL   (United Kingdom)

ⁱ UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; AUTOPHOSPHORYLATION; CATALYTIC EFFICIENCIES; CONFORMATIONAL CHANGE; DOMAIN-CONTAINING PROTEINS; GLUCOSE-STIMULATED INSULIN SECRETIONS; HEK293 CELLS; HYPERSECRETION; INSULIN RELEASE; INSULIN SECRETION; INSULIN SENSITIVITY; KINASE ACTIVITY; MATURITY-ONSET DIABETES OF THE YOUNG; PANCREATIC ISLET; PROTEIN KINASE; WILD TYPES;

AMINO ACIDS; ENZYMES; GENES; GLUCOSE; PHYSIOLOGY; PROTEINS;

INSULIN;

ADENOVIRUS VECTOR; GLUCAGON; GLUCOSE; GLYCINE; INSULIN; PER ARNT SIM DOMAIN CONTAINING PROTEIN KINASE; PROTEIN KINASE; THREONINE; UNCLASSIFIED DRUG;

ADENOVIRUS INFECTION; ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHOSPHORYLATION; CATALYSIS; CELL STRAIN HEK293; CLINICAL ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; FAMILY; FEMALE; GENE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; INSULIN RELEASE; MALE; MATURITY ONSET DIABETES MELLITUS; MOUSE; MUTANT; NONHUMAN; PANCREAS ISLET; PASK GENE; PRIORITY JOURNAL; WILD TYPE;

ADULT; ANIMALS; CELL LINE; DIABETES MELLITUS; GENOMICS; GLUCAGON; GLUCOSE; HEK293 CELLS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INSULIN; ISLETS OF LANGERHANS; MALE; MEMBRANE PROTEINS; MODELS, GENETIC; MUTAGENESIS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, WISTAR; RECOMBINANT PROTEINS;

EID: 83755181452     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.254995     Document Type: Article

References (35)

1. Hofer, T., Spielmann, P., Stengel, P., Stier, B., Katschinski, D. M., Desbaillets, I., Gassmann, M., and Wenger, R. H. (2001) Biochem. Biophys. Res. Commun. 288, 757-764
2. Rutter, J., Michnoff, C. H., Harper, S. M., Gardner, K. H., and McKnight, S. L. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 8991-8996
3. Möglich, A., Ayers, R. A., and Moffat, K. (2009) Structure 17, 1282-1294
4. Katschinski, D. M., Marti, H. H., Wagner, K. F., Shibata, J., Eckhardt, K., Martin, F., Depping, R., Paasch, U., Gassmann, M., Ledermann, B., Desbaillets, I., and Wenger, R. H. (2003) Mol. Cell. Biol. 23, 6780-6789
5. Borter, E., Niessen, M., Zuellig, R., Spinas, G. A., Spielmann, P., Camenisch, G., and Wenger, R. H. (2007) Diabetes 56, 113-117
6. Hao, H. X., Cardon, C. M., Swiatek, W., Cooksey, R. C., Smith, T. L., Wilde, J., Boudina, S., Abel, E. D., McClain, D. A., and Rutter, J. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 15466-15471
7. da Silva Xavier, G., Rutter, J., and Rutter, G. A. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 8319-8324
8. Fontés, G., Semache, M., Hagman, D. K., Tremblay, C., Shah, R., Rhodes, C. J., Rutter, J., and Poitout, V. (2009) Diabetes 58, 2048-2058
9. Soliz, J., Soulage, C., Borter, E., van Patot, M. T., and Gassmann, M. (2008) Am. J. Physiol. Regul. Integr. Comp. Physiol. 295, R649-R658
10. da Silva Xavier, G., Farhan, H., Kim, H., Caxaria, S., Johnson, P., Hughes, S., Bugliani, M., Marselli, L., Marchetti, P., Birzele, F., Sun, G., Scharfmann, R., Rutter, J., Siniakowicz, K., Weir, G., Parker, H., Reimann, F., Gribble, F., and Rutter, G. A. (2011) Diabetologia 54, 819-827
11. Amezcua, C. A., Harper, S. M., Rutter, J., and Gardner, K. H. (2002) Structure 10, 1349-1361
12. Schlafli, P., Troger, J., Eckhardt, K., Borter, E., Spielmann, P., and Wenger, R. H. (2011) FEBS J. 278, 1757-1768
13. Smith, T. L., and Rutter, J. (2007) Mol. Cell 26, 491-499
14. Grose, J. H., Sundwall, E., and Rutter, J. (2009) Cell Cycle 8, 1824-1832
15. Eckhardt, K., Troger, J., Reissmann, J., Katschinski, D. M., Wagner, K. F., Stengel, P., Paasch, U., Hunziker, P., Borter, E., Barth, S., Schlafli, P., Spielmann, P., Stiehl, D. P., Camenisch, G., and Wenger, R. H. (2007) Cell Physiol. Biochem. 20, 227-240
16. Wilson, W. A., Skurat, A. V., Probst, B., de Paoli-Roach, A., Roach, P. J., and Rutter, J. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 16596-16601
17. Vaxillaire, M., and Froguel, P. (2008) Endocr. Rev. 29, 254-264
18. Frayling, T. M., Lindgren, C. M., Chevre, J. C., Menzel, S., Wishart, M., Benmezroua, Y., Brown, A., Evans, J. C., Rao, P. S., Dina, C., Lecoeur, C., Kanninen, T., Almgren, P., Bulman, M. P., Wang, Y., Mills, J., Wright-Pascoe, R., Mahtani, M. M., Prisco, F., Costa, A., Cognet, I., Hansen, T., Pedersen, O., Ellard, S., Tuomi, T., Groop, L. C., Froguel, P., Hattersley, A. T., and Vaxillaire, M. (2003) Diabetes 52, 872-881
19. Chèvre, J. C., Hani, E. H., Boutin, P., Vaxillaire, M., Blanché, H., Vionnet, N., Pardini, V. C., Timsit, J., Larger, E., Charpentier, G., Beckers, D., Maes, M., Bellanné-Chantelot, C., Velho, G., and Froguel, P. (1998) Diabetologia 41, 1017-1023
20. Dale, S., Wilson, W. A., Edelman, A. M., and Hardie, D. G. (1995) FEBS Lett. 361, 191-195
21. Horton, R. M., Hunt, H. D., Ho, S. N., Pullen, J. K., and Pease, L. R. (1989) Gene 77, 61-68
22. Luo, J., Deng, Z. L., Luo, X., Tang, N., Song, W. X., Chen, J., Sharff, K. A., Luu, H. H., Haydon, R. C., Kinzler, K. W., Vogelstein, B., and He, T. C. (2007) Nat. Protocols 2, 1236-1247
23. Ainscow, E. K., Zhao, C., and Rutter, G. A. (2000) Diabetes 49, 1149-1155
24. Sun, G., Tarasov, A. I., McGinty, J., McDonald, A., da Silva Xavier, G., Gorman, T., Marley, A., French, P. M., Parker, H., Gribble, F., Reimann, F., Prendiville, O., Carzaniga, R., Viollet, B., Leclerc, I., and Rutter, G. A. (2010) Diabetologia 53, 924-936
25. Ravier, M. A., and Rutter, G. A. (2005) Diabetes 54, 1789-1797
26. Leclerc, I., Woltersdorf, W. W., da Silva Xavier, G., Rowe, R. L., Cross, S. E., Korbutt, G. S., Rajotte, R. V., Smith, R., and Rutter, G. A. (2004) Am. J. Physiol. Endocrinol. Metab. 286, E1023-E1031
27. Diraison, F., Motakis, E., Parton, L. E., Nason, G. P., Leclerc, I., and Rutter, G. A. (2004) Diabetes 53, Suppl. 3, S84-S91
28. Diraison, F., Parton, L., Ferré, P., Foufelle, F., Briscoe, C. P., Leclerc, I., and Rutter, G. A. (2004) Biochem. J. 378, 769-778
29. Mukai, E., Fujimoto, S., Sakurai, F., Kawabata, K., Yamashita, M., Inagaki, N., and Mizuguchi, H. (2007) J. Control. Release 119, 136-141
30. Rozen, S., and Skaletsky, H. (2000) Methods Mol. Biol. 132, 365-386
31. Kharouta, M., Miller, K., Kim, A., Wojcik, P., Kilimnik, G., Dey, A., Steiner, D. F., and Hara, M. (2009) Diabetes Res. Clin. Pract. 85, 252-257
32. Evans-Molina, C., Garmey, J. C., Ketchum, R., Brayman, K. L., Deng, S., and Mirmira, R. G. (2007) Diabetes 56, 827-835
33. Iype, T., Francis, J., Garmey, J. C., Schisler, J. C., Nesher, R., Weir, G. C., Becker, T. C., Newgard, C. B., Griffen, S. C., and Mirmira, R. G. (2005) J. Biol. Chem. 280, 16798-16807
34. Kikani, C. K., Antonysamy, S. A., Bonanno, J. B., Romero, R., Zhang, F. F., Russell, M., Gheyi, T., Iizuka, M., Emtage, S., Sauder, J. M., Turk, B. E., Burley, S. K., and Rutter, J. (2010) J. Biol. Chem. 285, 41034-41043
35. Ravier, M. A., Cheng-Xue, R., Palmer, A. E., Henquin, J. C., and Gilon, P. (2010) Diabetologia 53, 1947-1957