CK2 phosphorylation of Pdx-1 regulates its transcription factor activity

Cellular and Molecular Life Sciences

Volumn 67, Issue 14, 2010, Pages 2481-2489

  Meng, Rui ^a   Al Quobaili, Faizeh ^a,b   Müller, Isabelle ^a   Götz, Claudia ^a   Thiel, Gerald ^a   Montenarh, Mathias ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b DAMASCUS UNIVERSITY   (Syrian Arab Republic)

Author keywords

Homeobox protein; Insulin production; Phosphorylation; Protein kinase; Transcription factor

Indexed keywords

CASEIN KINASE II; INSULIN; SERINE; THREONINE; TRANSCRIPTION FACTOR PDX 1; ENZYME INHIBITOR; HOMEODOMAIN PROTEIN; INSULIN PROMOTER FACTOR 1; TRANSACTIVATOR PROTEIN;

ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME INHIBITION; HUMAN; HUMAN CELL; INSULIN METABOLISM; INSULIN RELEASE; MUTANT; PANCREAS ISLET BETA CELL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; TRANSACTIVATION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; DRUG ANTAGONISM; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; PHOSPHORYLATION; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

AMINO ACID SEQUENCE; ANIMALS; CASEIN KINASE II; CELL LINE; CELL LINE, TUMOR; ENZYME INHIBITORS; HOMEODOMAIN PROTEINS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MICE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION;

EID: 77954617281     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0348-0     Document Type: Article

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