Medicinal attributes of pyrazolo[3,4-d]pyrimidines: A review

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 18, 2013, Pages 5657-5668

  Chauhan, Monika ^a   Kumar, Raj ^a  

^a CENTRAL UNIVERSITY OF PUNJAB   (India)

Author keywords

Activities; IC50; Pyrazolo 3,4 d pyrimidine; SAR

Indexed keywords

2 ARYLTHIENOL[3,2 D]PYRIMIDINE DERIVATIVE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 5 AMINO 1 PHENYL 1,5 DIHYDROPYRAZOLO[3,4 D]PYRIMIDINE; 6 ARYL 1H PYRAZOLO[3,4 A]PYRIMIDINE DERIVATIVE; ABELSON KINASE; ADENOSINE DEAMINASE INHIBITOR; ANGIOPOIETIN RECEPTOR; ANTINEOPLASTIC AGENT; AURORA KINASE INHIBITOR; CYCLIN DEPENDENT KINASE 1; DIAMINE DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; GYRASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE 14; N3,N6 DIARYL 1H PYRAZOLO[3,4 D]PYRIMIDINE 3,6 DIAMINE DERIVATIVE; N6 PHENYL 1HG PYRAZOLO[3,4 D]PYRIMIDINE 3,6 DIAMINE DERIVATIVE; PROTEIN KINASE B INHIBITOR; PROTEIN KINASE INHIBITOR; PROTEIN KINASE LCK; PROTEIN TYROSINE KINASE INHIBITOR; PYRAZOLO[3,4 A]PYRIMIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; RADIOPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; S6 KINASE; SOMATOMEDIN C RECEPTOR; UNC 1062; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN RECEPTOR 2; XANTHINE OXIDASE INHIBITOR;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ANTIVIRAL ACTIVITY; COLITIS; CONCENTRATION RESPONSE; DRUG MECHANISM; DRUG SYNTHESIS; NONHUMAN; RADIATION PROTECTION; REVIEW; STRUCTURE ACTIVITY RELATION;

MUS; RATTUS;

ACTIVITIES; IC(50); PYRAZOLO[3,4-D]PYRIMIDINE; SAR;

ADENOSINE DEAMINASE INHIBITORS; ANIMALS; ANTI-INFECTIVE AGENTS; ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; BACTERIA; FUNGI; HUMANS; NEOPLASMS; PROTEIN KINASE INHIBITORS; PYRAZOLES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUSES; XANTHINE OXIDASE;

EID: 84882898480     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.07.027     Document Type: Review

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