Synthesis and antiviral evaluation of some new pyrazole and fused pyrazolopyrimidine derivatives

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 15, 2008, Pages 7102-7106

  Rashad, Aymn E ^a   Hegab, Mohamed I ^a   Abdel Megeid, Randa E ^a   Micky, Jehan A ^b   Abdel Megeid, Farouk M E ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b AL AZHAR UNIVERSITY   (Egypt)

Author keywords

Antiviral activity; Pyrazole; Pyrazolo 3,4 d pyrimidine; S and N nucleosides

Indexed keywords

1 (5,6 DIHYDRONAPHTHO[1',2':4,5]THIENO[2,3 D]PYRIMIDIN 11 YL) 1H PYRAZOLO[3,4 D]PYRIMIDINE 4 (3H)THIONE; 4 (2 HYDROXYETHYLSULFANYL) 1 (5,6 DIHYDRONAPHTHO[1',2':4,5]THIENO[2,3 D]PYRIMIDIN 11 YL) 1H PYRAZOLO[3,4 D]PYRIMIDINE; 4 (2 METHOXYETHYLSULFANYL) 1 (5,6 DIHYDRONAPHTHO[1',2':4,5]THIENO[2,3 D]PYRIMIDIN 11 YL) 1H PYRAZOLO[3,4 D]PYRIMIDINE; 4 (DIMETHOXYETHYLSULFANYL) 1 (5,6 DIHYDRONAPHTHO[1',2':4,5]THIENO[2,3 D]PYRIMIDIN 11 YL) 1H PYRAZOLO[3,4 D]PYRIMIDINE; 4 (HYDROXYETHYLSULFANYL) 1 (5,6 DIHYDRONAPHTHO[1',2':4,5]THIENO[2,3 D]PYRIMIDIN 11 YL) 1H PYRAZOLO[3,4 D]PYRIMIDINE; 4 AMINO 1 (5,6 DIHYDRONAPHTHO[1',2':4,5]THIENO[2,3 D]PYRIMIDIN 11 YL) 1H PYRAZOLO[3,4 D]PYRIMIDIN 6(5H)THIONE; 4 CHLORO 1 (5,6 DIHYDRONAPHTHO[1',2':4,5]THIENO[2,3 D]PYRIMIDIN 11 YL) 1H PYRAZOLO[3,4 D]PYRIMIDINE; GLUCOSAMINE; N [1 (5,6 DIHYDRONAPHTHO[1',2':4,5]THIENO[2,3 D]PYRIMIDIN 11 YL) 1H PYRAZOLO[3,4 D]PYRIMIDINE]GLUCOSAMINE; N BENZOYL N' [4 CYANO 1 (5,6 DIHYDRONAPHTHO[1',2':4,5]THIENO[2,3 D]PYRIMIDIN 11 YL) 1H PYRAZOL 5 YL]THIOUREA; NUCLEOSIDE; PYRAZOLE; PYRAZOLE DERIVATIVE; PYRAZOLOPYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; BIOASSAY; CELL CULTURE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HEPATITIS A VIRUS; HERPES SIMPLEX VIRUS 1; NONHUMAN;

ANTIVIRAL AGENTS; HEPATITIS A VIRUS; HERPESVIRUS 1, HUMAN; MOLECULAR STRUCTURE; PLAQUE ASSAY; PYRAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

HEPATITIS A VIRUS; HUMAN HERPESVIRUS 1;

EID: 48449100032     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.06.054     Document Type: Article

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