Synthesis of some novel pyrazolo[3,4-d]pyrimidine derivatives as potential antimicrobial agents

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 6, 2006, Pages 2040-2047

  Holla, Bantwal Shivarama ^a   Mahalinga, Manjathuru ^a   Karthikeyan, Mari Sitambaram ^a   Akberali, Padiyath Mohamed ^b   Shetty, Nalilu Sucheta ^c  

^a MANGALORE UNIVERSITY   (India)

^b Strides Arcolab Limited   (India)

^c NITTE DEEMED TO BE UNIVERSITY   (India)

Author keywords

4 Hydrazino 8 (trifluoromethyl)quinoline; Antibacterial; Antifungal activity studies; Pyrazolopyrimidines

Indexed keywords

1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1H PYRAZOLO[3,4 D]PYRIMIDIN 4,6(6H,7H) DIONE; 4 AMINO 1[8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,7 DIHYDRO 6H PYRAZOLO[3,4 D]PYRIMIDIN 6 ONE; 4 AMINO 1[8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1H PYRAZOLO[3,4 D]PYRIMIDIN 6 THIONE; 4 AMINO 1[8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1H PYRAZOLO[3,4 D]PYRIMIDINE; 4 HYDRAZINO 8 (TRIFLUOROMETHYL)QUINOLINE; 5 (2,5 DICHOLOROPHENYL) 6 METHYL 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 5 (3 CHLORO 4 FLUOROPHENYL) 6 METHYL 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 5 (3,4 DICHOLOROPHENYL) 6 METHYL 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 5 (4 CHOLOROPHENYL) 6 METHYL 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 5 (4 FLUOROPHENYL) 6 METHYL 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 5 (5 CHLORO 2 METHYLPHENYL) 6 METHYL 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 6 METHYL 5 (2 METHYLPHENYL) 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 6 METHYL 5 (2,4,5 TRICHOLOROPHENYL) 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 6 METHYL 5 (4 METHYL 2 NITROPHENYL) 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 6 METHYL 5 (4 METHYLPHENYL) 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 6 METHYL 5 (4 NITROPHENYL) 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 6 METHYL 5 [2 (TRIFLUOROMETHYL)PHENYL) 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 6 METHYL 5 PHENYL 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; 6 THIOXO 1 [8 (TRIFLUOROMETHYL)QUINOLIN 4 YL] 1,5 DIHYDRO 4H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; ANTIINFECTIVE AGENT; ETHOXYMETHYLENECYANOACETATE; PYRAZOLO[3,4 D]PYRIMIDINE DERIVATIVE; QUINOLINE DERIVATIVE; STREPTOMYCIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; CHEMICAL REACTION; CONTROLLED STUDY; DRUG HYDROLYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; NONHUMAN; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

ANTI-INFECTIVE AGENTS; BACTERIA; FUNGI; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PYRAZOLES; PYRIMIDINES;

BACILLUS SUBTILIS; ESCHERICHIA COLI; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 32044468685     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.10.053     Document Type: Article

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