-
1
-
-
68949163251
-
Regulation of osteogenesis-angiogenesis coupling by HIFs and VEGF
-
Schipani E, Maes C, Carmeliet G, Semenza GL., Regulation of osteogenesis-angiogenesis coupling by HIFs and VEGF. J Bone Miner Res. 2009; 24 (8): 1347-53.
-
(2009)
J Bone Miner Res.
, vol.24
, Issue.8
, pp. 1347-1353
-
-
Schipani, E.1
Maes, C.2
Carmeliet, G.3
Semenza, G.L.4
-
2
-
-
0036166701
-
Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188
-
Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G., Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Mech Dev. 2002; 111 (1-2): 61-73.
-
(2002)
Mech Dev.
, vol.111
, Issue.12
, pp. 61-73
-
-
Maes, C.1
Carmeliet, P.2
Moermans, K.3
Stockmans, I.4
Smets, N.5
Collen, D.6
Bouillon, R.7
Carmeliet, G.8
-
3
-
-
34249913494
-
The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development
-
Wang Y, Wan C, Deng L, Liu X, Cao X, Gilbert SR, Bouxsein ML, Faugere MC, Guldberg RE, Gerstenfeld LC, Haase VH, Johnson RS, Schipani E, Clemens TL., The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. J Clin Invest. 2007; 117 (6): 1616-26.
-
(2007)
J Clin Invest.
, vol.117
, Issue.6
, pp. 1616-1626
-
-
Wang, Y.1
Wan, C.2
Deng, L.3
Liu, X.4
Cao, X.5
Gilbert, S.R.6
Bouxsein, M.L.7
Faugere, M.C.8
Guldberg, R.E.9
Gerstenfeld, L.C.10
Haase, V.H.11
Johnson, R.S.12
Schipani, E.13
Clemens, T.L.14
-
4
-
-
38649128127
-
Activation of the hypoxia-inducible factor-1alpha pathway accelerates bone regeneration
-
Wan C, Gilbert SR, Wang Y, Cao X, Shen X, Ramaswamy G, Jacobsen KA, Alaql ZS, Eberhardt AW, Gerstenfeld LC, Einhorn TA, Deng L, Clemens TL., Activation of the hypoxia-inducible factor-1alpha pathway accelerates bone regeneration. Proc Natl Acad Sci USA. 2008; 105 (2): 686-91.
-
(2008)
Proc Natl Acad Sci USA.
, vol.105
, Issue.2
, pp. 686-691
-
-
Wan, C.1
Gilbert, S.R.2
Wang, Y.3
Cao, X.4
Shen, X.5
Ramaswamy, G.6
Jacobsen, K.A.7
Alaql, Z.S.8
Eberhardt, A.W.9
Gerstenfeld, L.C.10
Einhorn, T.A.11
Deng, L.12
Clemens, T.L.13
-
5
-
-
42449132519
-
Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling
-
Jacobsen KA, Al-Aql ZS, Wan C, Fitch JL, Stapleton SN, Mason ZD, Cole RM, Gilbert SR, Clemens TL, Morgan EF, Einhorn TA, Gerstenfeld LC., Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling. J Bone Miner Res. 2008; 23 (5): 596-609.
-
(2008)
J Bone Miner Res.
, vol.23
, Issue.5
, pp. 596-609
-
-
Jacobsen, K.A.1
Al-Aql, Z.S.2
Wan, C.3
Fitch, J.L.4
Stapleton, S.N.5
Mason, Z.D.6
Cole, R.M.7
Gilbert, S.R.8
Clemens, T.L.9
Morgan, E.F.10
Einhorn, T.A.11
Gerstenfeld, L.C.12
-
6
-
-
0037162547
-
Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover
-
Street J, Bao M, deGuzman L, Bunting S, Peale FV Jr, Ferrara N, Steinmetz H, Hoeffel J, Cleland JL, Daugherty A, van Bruggen N, Redmond HP, Carano RA, Filvaroff EH., Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. Proc Natl Acad Sci USA. 2002; 99 (15): 9656-61.
-
(2002)
Proc Natl Acad Sci USA.
, vol.99
, Issue.15
, pp. 9656-9661
-
-
Street, J.1
Bao, M.2
Deguzman, L.3
Bunting, S.4
Peale, Jr.F.V.5
Ferrara, N.6
Steinmetz, H.7
Hoeffel, J.8
Cleland, J.L.9
Daugherty, A.10
Van Bruggen, N.11
Redmond, H.P.12
Carano, R.A.13
Filvaroff, E.H.14
-
7
-
-
84866001590
-
Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation
-
Liu Y, Berendsen AD, Jia S, Lotinun S, Baron R, Ferrara N, Olsen BR., Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation. J Clin Invest. 2012; 122 (9): 3101-13.
-
(2012)
J Clin Invest.
, vol.122
, Issue.9
, pp. 3101-3113
-
-
Liu, Y.1
Berendsen, A.D.2
Jia, S.3
Lotinun, S.4
Baron, R.5
Ferrara, N.6
Olsen, B.R.7
-
8
-
-
37249048812
-
A novel transgenic mouse model to study the osteoblast lineage in vivo
-
Maes C, Kobayashi T, Kronenberg HM., A novel transgenic mouse model to study the osteoblast lineage in vivo. Ann NY Acad Sci. 2007; 1116: 149-64.
-
(2007)
Ann NY Acad Sci.
, vol.1116
, pp. 149-164
-
-
Maes, C.1
Kobayashi, T.2
Kronenberg, H.M.3
-
9
-
-
74949111983
-
Osteoclasts are important for bone angiogenesis
-
Cackowski FC, Anderson JL, Patrene KD, Choksi RJ, Shapiro SD, Windle JJ, Blair HC, Roodman GD., Osteoclasts are important for bone angiogenesis. Blood. 2010; 115 (1): 140-9.
-
(2010)
Blood.
, vol.115
, Issue.1
, pp. 140-149
-
-
Cackowski, F.C.1
Anderson, J.L.2
Patrene, K.D.3
Choksi, R.J.4
Shapiro, S.D.5
Windle, J.J.6
Blair, H.C.7
Roodman, G.D.8
-
10
-
-
77951203173
-
Osteoclast-derived matrix metalloproteinase-9 directly affects angiogenesis in the prostate tumor-bone microenvironment
-
Bruni-Cardoso A, Johnson LC, Vessella RL, Peterson TE, Lynch CC., Osteoclast-derived matrix metalloproteinase-9 directly affects angiogenesis in the prostate tumor-bone microenvironment. Mol Cancer Res. 2010; 8 (4): 459-70.
-
(2010)
Mol Cancer Res.
, vol.8
, Issue.4
, pp. 459-470
-
-
Bruni-Cardoso, A.1
Johnson, L.C.2
Vessella, R.L.3
Peterson, T.E.4
Lynch, C.C.5
-
11
-
-
0036828845
-
Leu-574 of HIF-1alpha is essential for the von Hippel-Lindau (VHL)-mediated degradation pathway
-
Huang LE, Pete EA, Schau M, Milligan J, Gu J., Leu-574 of HIF-1alpha is essential for the von Hippel-Lindau (VHL)-mediated degradation pathway. J Biol Chem. 2002; 277 (44): 41750-5.
-
(2002)
J Biol Chem.
, vol.277
, Issue.44
, pp. 41750-41755
-
-
Huang, L.E.1
Pete, E.A.2
Schau, M.3
Milligan, J.4
Gu, J.5
-
12
-
-
0032493368
-
Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway
-
Huang LE, Gu J, Schau M, Bunn HF., Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway. Proc Natl Acad Sci USA. 1998; 95 (14): 7987-92.
-
(1998)
Proc Natl Acad Sci USA.
, vol.95
, Issue.14
, pp. 7987-7992
-
-
Huang, L.E.1
Gu, J.2
Schau, M.3
Bunn, H.F.4
-
13
-
-
0242330181
-
Oxygen sensing in the hypoxic response pathway: Regulation of the hypoxia-inducible transcription factor
-
Bruick RK., Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor. Genes Dev. 2003; 17 (21): 2614-23.
-
(2003)
Genes Dev.
, vol.17
, Issue.21
, pp. 2614-2623
-
-
Bruick, R.K.1
-
14
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ., The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature. 1999; 399 (6733): 271-5.
-
(1999)
Nature.
, vol.399
, Issue.6733
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
15
-
-
0036718539
-
Molecular basis of the VHL hereditary cancer syndrome
-
Kaelin WG Jr., Molecular basis of the VHL hereditary cancer syndrome. Nat Rev Cancer. 2002; 2 (9): 673-82.
-
(2002)
Nat Rev Cancer.
, vol.2
, Issue.9
, pp. 673-682
-
-
Kaelin, Jr.W.G.1
-
16
-
-
0032538797
-
Signal transduction in hypoxic cells: Inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha
-
Kallio PJ, Okamoto K, O'Brien S, Carrero P, Makino Y, Tanaka H, Poellinger L., Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha. EMBO J. 1998; 17 (22): 6573-86.
-
(1998)
EMBO J.
, vol.17
, Issue.22
, pp. 6573-6586
-
-
Kallio, P.J.1
Okamoto, K.2
O'Brien, S.3
Carrero, P.4
Makino, Y.5
Tanaka, H.6
Poellinger, L.7
-
17
-
-
0035887011
-
FIH-1: A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity
-
Mahon PC, Hirota K, Semenza GL., FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev. 2001; 15 (20): 2675-86.
-
(2001)
Genes Dev.
, vol.15
, Issue.20
, pp. 2675-2686
-
-
Mahon, P.C.1
Hirota, K.2
Semenza, G.L.3
-
18
-
-
0037097861
-
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
-
Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML, Bruick RK., FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev. 2002; 16 (12): 1466-71.
-
(2002)
Genes Dev.
, vol.16
, Issue.12
, pp. 1466-1471
-
-
Lando, D.1
Peet, D.J.2
Gorman, J.J.3
Whelan, D.A.4
Whitelaw, M.L.5
Bruick, R.K.6
-
19
-
-
31444444162
-
Integration of oxygen signaling at the consensus HRE
-
re12.
-
Wenger RH, Stiehl DP, Camenisch G., Integration of oxygen signaling at the consensus HRE. Sci STKE. 2005; 306: re12.
-
(2005)
Sci STKE.
, vol.306
-
-
Wenger, R.H.1
Stiehl, D.P.2
Camenisch, G.3
-
20
-
-
4444311880
-
Hypoxia inducible factor-1alpha as a cancer drug target
-
Powis G, Kirkpatrick L., Hypoxia inducible factor-1alpha as a cancer drug target. Mol Cancer Ther. 2004; 3 (5): 647-54.
-
(2004)
Mol Cancer Ther.
, vol.3
, Issue.5
, pp. 647-654
-
-
Powis, G.1
Kirkpatrick, L.2
-
21
-
-
0026728645
-
Molecular cloning of human CREB-2: An ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element
-
Karpinski BA, Morle GD, Huggenvik J, Uhler MD, Leiden JM., Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element. Proc Natl Acad Sci USA. 1992; 89 (11): 4820-4.
-
(1992)
Proc Natl Acad Sci USA.
, vol.89
, Issue.11
, pp. 4820-4824
-
-
Karpinski, B.A.1
Morle, G.D.2
Huggenvik, J.3
Uhler, M.D.4
Leiden, J.M.5
-
22
-
-
0026019435
-
Isolation of cDNAs for DNA-binding proteins which specifically bind to a tax-responsive enhancer element in the long terminal repeat of human T-cell leukemia virus type i
-
Tsujimoto A, Nyunoya H, Morita T, Sato T, Shimotohno K., Isolation of cDNAs for DNA-binding proteins which specifically bind to a tax-responsive enhancer element in the long terminal repeat of human T-cell leukemia virus type I. J Virol. 1992; 65 (3): 1420-6.
-
(1992)
J Virol.
, vol.65
, Issue.3
, pp. 1420-1426
-
-
Tsujimoto, A.1
Nyunoya, H.2
Morita, T.3
Sato, T.4
Shimotohno, K.5
-
23
-
-
0035861198
-
Identification of tooth-specific downstream targets of Runx2
-
Gaikwad JS, Cavender A, D'Souza RN., Identification of tooth-specific downstream targets of Runx2. Gene. 2001; 279 (1): 91-7.
-
(2001)
Gene.
, vol.279
, Issue.1
, pp. 91-97
-
-
Gaikwad, J.S.1
Cavender, A.2
D'Souza, R.N.3
-
24
-
-
0027195403
-
Cyclic adenosine 3',5'-monophosphate response element binding protein (CREB) and related transcription-activating deoxyribonucleic acid-binding proteins
-
Meyer TE, Habener JF., Cyclic adenosine 3',5'-monophosphate response element binding protein (CREB) and related transcription-activating deoxyribonucleic acid-binding proteins. Endocr Rev. 1993; 14 (3): 269-90.
-
(1993)
Endocr Rev.
, vol.14
, Issue.3
, pp. 269-290
-
-
Meyer, T.E.1
Habener, J.F.2
-
25
-
-
0027973543
-
Goals for signal transduction pathways: Linking up with transcriptional regulation
-
Sassone-Corsi P., Goals for signal transduction pathways: linking up with transcriptional regulation. Embo J. 1994; 13 (20): 4717-28.
-
(1994)
Embo J.
, vol.13
, Issue.20
, pp. 4717-4728
-
-
Sassone-Corsi, P.1
-
26
-
-
0025120194
-
Transcription factors: A new family gathers at the cAMP response site
-
Ziff EB., Transcription factors: a new family gathers at the cAMP response site. Trends Genet. 1990; 6 (3): 69-72.
-
(1990)
Trends Genet.
, vol.6
, Issue.3
, pp. 69-72
-
-
Ziff, E.B.1
-
27
-
-
0026846986
-
The CREB family of transcription activators
-
Brindle PK, Montminy MR., The CREB family of transcription activators. Curr Opin Genet Dev. 1992; 2 (2): 199-204.
-
(1992)
Curr Opin Genet Dev.
, vol.2
, Issue.2
, pp. 199-204
-
-
Brindle, P.K.1
Montminy, M.R.2
-
28
-
-
11144357428
-
ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; Implication for Coffin-Lowry Syndrome
-
Yang X, Matsuda K, Bialek P, Jacquot S, Masuoka HC, Schinke T, Li L, Brancorsini S, Sassone-Corsi P, Townes TM, Hanauer A, Karsenty G., ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell. 2004; 117 (3): 387-98.
-
(2004)
Cell.
, vol.117
, Issue.3
, pp. 387-398
-
-
Yang, X.1
Matsuda, K.2
Bialek, P.3
Jacquot, S.4
Masuoka, H.C.5
Schinke, T.6
Li, L.7
Brancorsini, S.8
Sassone-Corsi, P.9
Townes, T.M.10
Hanauer, A.11
Karsenty, G.12
-
29
-
-
54849403883
-
Activating transcription factor 4 is critical for proliferation and survival in primary bone marrow stromal cells and calvarial osteoblasts
-
Zhang X, Yu S, Galson DL, Luo M, Fan J, Zhang J, Guan Y, Xiao G., Activating transcription factor 4 is critical for proliferation and survival in primary bone marrow stromal cells and calvarial osteoblasts. J Cell Biochem. 2008; 105 (3): 885-95.
-
(2008)
J Cell Biochem.
, vol.105
, Issue.3
, pp. 885-895
-
-
Zhang, X.1
Yu, S.2
Galson, D.L.3
Luo, M.4
Fan, J.5
Zhang, J.6
Guan, Y.7
Xiao, G.8
-
30
-
-
8744224520
-
ATF4, the osteoblast accumulation of which is determined post-translationally, can induce osteoblast-specific gene expression in non-osteoblastic cells
-
Yang X, Karsenty G., ATF4, the osteoblast accumulation of which is determined post-translationally, can induce osteoblast-specific gene expression in non-osteoblastic cells. J Biol Chem. 2004; 279 (45): 47109-14.
-
(2004)
J Biol Chem.
, vol.279
, Issue.45
, pp. 47109-47114
-
-
Yang, X.1
Karsenty, G.2
-
31
-
-
41549122869
-
Parathyroid hormone increases activating transcription factor 4 expression and activity in osteoblasts: Requirement for osteocalcin gene expression
-
Yu S, Franceschi RT, Luo M, Zhang X, Jiang D, Lai Y, Jiang Y, Zhang J, Xiao G., Parathyroid hormone increases activating transcription factor 4 expression and activity in osteoblasts: requirement for osteocalcin gene expression. Endocrinology. 2008; 149 (4): 1960-8.
-
(2008)
Endocrinology.
, vol.149
, Issue.4
, pp. 1960-1968
-
-
Yu, S.1
Franceschi, R.T.2
Luo, M.3
Zhang, X.4
Jiang, D.5
Lai, Y.6
Jiang, Y.7
Zhang, J.8
Xiao, G.9
-
32
-
-
41949123120
-
General transcription factor IIA-gamma increases osteoblast-specific osteocalcin gene expression via activating transcription factor 4 and runt-related transcription factor 2
-
Yu S, Jiang Y, Galson DL, Luo M, Lai Y, Lu Y, Ouyang HJ, Zhang J, Xiao G., General transcription factor IIA-gamma increases osteoblast-specific osteocalcin gene expression via activating transcription factor 4 and runt-related transcription factor 2. J Biol Chem. 2008; 283 (9): 5542-53.
-
(2008)
J Biol Chem.
, vol.283
, Issue.9
, pp. 5542-5553
-
-
Yu, S.1
Jiang, Y.2
Galson, D.L.3
Luo, M.4
Lai, Y.5
Lu, Y.6
Ouyang, H.J.7
Zhang, J.8
Xiao, G.9
-
33
-
-
70449552809
-
Critical role of activating transcription factor 4 in the anabolic actions of parathyroid hormone in bone
-
Yu S, Franceschi RT, Luo M, Fan J, Jiang D, Cao H, Kwon TG, Lai Y, Zhang J, Patrene K, Hankenson K, Roodman GD, Xiao G., Critical role of activating transcription factor 4 in the anabolic actions of parathyroid hormone in bone. PLoS One. 2009; 4 (10): e7583.
-
(2009)
PLoS One.
, vol.4
, Issue.10
-
-
Yu, S.1
Franceschi, R.T.2
Luo, M.3
Fan, J.4
Jiang, D.5
Cao, H.6
Kwon, T.G.7
Lai, Y.8
Zhang, J.9
Patrene, K.10
Hankenson, K.11
Roodman, G.D.12
Xiao, G.13
-
34
-
-
24744458827
-
Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression
-
Xiao G, Jiang D, Ge C, Zhao Z, Lai Y, Boules H, Phimphilai M, Yang X, Karsenty G, Franceschi RT., Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression. J Biol Chem. 2005; 280 (35): 30689-96.
-
(2005)
J Biol Chem.
, vol.280
, Issue.35
, pp. 30689-30696
-
-
Xiao, G.1
Jiang, D.2
Ge, C.3
Zhao, Z.4
Lai, Y.5
Boules, H.6
Phimphilai, M.7
Yang, X.8
Karsenty, G.9
Franceschi, R.T.10
-
35
-
-
77955286526
-
Activating transcription factor 4 regulates osteoclast differentiation in mice
-
Cao H, Yu S, Yao Z, Galson DL, Jiang Y, Zhang X, Fan J, Lu B, Guan Y, Luo M, Lai Y, Zhu Y, Kurihara N, Patrene K, Roodman GD, Xiao G., Activating transcription factor 4 regulates osteoclast differentiation in mice. J Clin Invest. 2010; 120 (8): 2755-66.
-
(2010)
J Clin Invest.
, vol.120
, Issue.8
, pp. 2755-2766
-
-
Cao, H.1
Yu, S.2
Yao, Z.3
Galson, D.L.4
Jiang, Y.5
Zhang, X.6
Fan, J.7
Lu, B.8
Guan, Y.9
Luo, M.10
Lai, Y.11
Zhu, Y.12
Kurihara, N.13
Patrene, K.14
Roodman, G.D.15
Xiao, G.16
-
36
-
-
15844384047
-
Leptin regulation of bone resorption by the sympathetic nervous system and CART
-
Elefteriou F, Ahn JD, Takeda S, Starbuck M, Yang X, Liu X, Kondo H, Richards WG, Bannon TW, Noda M, Clement K, Vaisse C, Karsenty G., Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature. 2005; 434 (7032): 514-20.
-
(2005)
Nature.
, vol.434
, Issue.7032
, pp. 514-520
-
-
Elefteriou, F.1
Ahn, J.D.2
Takeda, S.3
Starbuck, M.4
Yang, X.5
Liu, X.6
Kondo, H.7
Richards, W.G.8
Bannon, T.W.9
Noda, M.10
Clement, K.11
Vaisse, C.12
Karsenty, G.13
-
37
-
-
33751412300
-
ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae
-
Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G., ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metab. 2006; 4 (6): 441-51.
-
(2006)
Cell Metab.
, vol.4
, Issue.6
, pp. 441-451
-
-
Elefteriou, F.1
Benson, M.D.2
Sowa, H.3
Starbuck, M.4
Liu, X.5
Ron, D.6
Parada, L.F.7
Karsenty, G.8
-
38
-
-
20144378800
-
The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanism
-
Roybal CN, Hunsaker LA, Barbash O, Vander Jagt DL, Abcouwer SF., The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanism. J Biol Chem. 2005; 280 (21): 20331-9.
-
(2005)
J Biol Chem.
, vol.280
, Issue.21
, pp. 20331-20339
-
-
Roybal, C.N.1
Hunsaker, L.A.2
Barbash, O.3
Vander Jagt, D.L.4
Abcouwer, S.F.5
-
39
-
-
77951479702
-
Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: Novel point of convergence between electrophilic and unfolded protein stress pathways
-
Afonyushkin T, Oskolkova OV, Philippova M, Resink TJ, Erne P, Binder BR, Bochkov VN., Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: novel point of convergence between electrophilic and unfolded protein stress pathways. Arterioscler Thromb Vasc Biol. 2010; 30 (5): 1007-13.
-
(2010)
Arterioscler Thromb Vasc Biol.
, vol.30
, Issue.5
, pp. 1007-1013
-
-
Afonyushkin, T.1
Oskolkova, O.V.2
Philippova, M.3
Resink, T.J.4
Erne, P.5
Binder, B.R.6
Bochkov, V.N.7
-
40
-
-
77949699965
-
Transcriptional regulation of VEGF-A by the unfolded protein response pathway
-
Ghosh R, Lipson KL, Sargent KE, Mercurio AM, Hunt JS, Ron D, Urano F., Transcriptional regulation of VEGF-A by the unfolded protein response pathway. PLoS One. 2010; 5 (3): e9575.
-
(2010)
PLoS One.
, vol.5
, Issue.3
-
-
Ghosh, R.1
Lipson, K.L.2
Sargent, K.E.3
Mercurio, A.M.4
Hunt, J.S.5
Ron, D.6
Urano, F.7
-
41
-
-
77952283596
-
The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A
-
Dedieu S, Canron X, Rezvani HR, Bouchecareilh M, Mazurier F, Sinisi R, Zanda M, Moenner M, Bikfalvi A, North S., The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A. BMC Med. 2010; 8: 19.
-
(2010)
BMC Med.
, vol.8
, pp. 19
-
-
Dedieu, S.1
Canron, X.2
Rezvani, H.R.3
Bouchecareilh, M.4
Mazurier, F.5
Sinisi, R.6
Zanda, M.7
Moenner, M.8
Bikfalvi, A.9
North, S.10
-
42
-
-
77958611209
-
Transcriptional and post-transcriptional regulation of proangiogenic factors by the unfolded protein response
-
Pereira ER, Liao N, Neale GA, Hendershot LM., Transcriptional and post-transcriptional regulation of proangiogenic factors by the unfolded protein response. PLoS One. 2010; 5 (9): e12521.
-
(2010)
PLoS One.
, vol.5
, Issue.9
-
-
Pereira, E.R.1
Liao, N.2
Neale, G.A.3
Hendershot, L.M.4
-
43
-
-
0035159670
-
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia
-
Stroka DM, Burkhardt T, Desbaillets I, Wenger RH, Neil DA, Bauer C, Gassmann M, Candinas D., HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia. FASEB J. 2001; 15 (13): 2445-53.
-
(2001)
FASEB J.
, vol.15
, Issue.13
, pp. 2445-2453
-
-
Stroka, D.M.1
Burkhardt, T.2
Desbaillets, I.3
Wenger, R.H.4
Neil, D.A.5
Bauer, C.6
Gassmann, M.7
Candinas, D.8
-
44
-
-
79956311528
-
Foxo1 mediates insulin-like growth factor 1 (IGF1)/insulin regulation of osteocalcin expression by antagonizing Runx2 in osteoblasts
-
Yang S, Xu H, Yu S, Cao H, Fan J, Ge C, Fransceschi RT, Dong HH, Xiao G., Foxo1 mediates insulin-like growth factor 1 (IGF1)/insulin regulation of osteocalcin expression by antagonizing Runx2 in osteoblasts. J Biol Chem. 2011; 286 (21): 19149-58.
-
(2011)
J Biol Chem.
, vol.286
, Issue.21
, pp. 19149-19158
-
-
Yang, S.1
Xu, H.2
Yu, S.3
Cao, H.4
Fan, J.5
Ge, C.6
Fransceschi, R.T.7
Dong, H.H.8
Xiao, G.9
-
45
-
-
0030794270
-
Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex
-
Banerjee C, McCabe LR, Choi JY, Hiebert SW, Stein JL, Stein GS, Lian JB., Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex. J Cell Biochem. 1997; 66 (1): 1-8.
-
(1997)
J Cell Biochem.
, vol.66
, Issue.1
, pp. 1-8
-
-
Banerjee, C.1
McCabe, L.R.2
Choi, J.Y.3
Hiebert, S.W.4
Stein, J.L.5
Stein, G.S.6
Lian, J.B.7
-
46
-
-
0030678549
-
Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation [see comments]
-
Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G., Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation [see comments]. Cell. 1997; 89 (5): 747-54.
-
(1997)
Cell.
, vol.89
, Issue.5
, pp. 747-754
-
-
Ducy, P.1
Zhang, R.2
Geoffroy, V.3
Ridall, A.L.4
Karsenty, G.5
-
47
-
-
0030684749
-
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts [see comments]
-
Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, Shimizu Y, Bronson RT, Gao YH, Inada M, Sato M, Okamoto R, Kitamura Y, Yoshiki S, Kishimoto T., Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts [see comments]. Cell. 1997; 89 (5): 755-64.
-
(1997)
Cell.
, vol.89
, Issue.5
, pp. 755-764
-
-
Komori, T.1
Yagi, H.2
Nomura, S.3
Yamaguchi, A.4
Sasaki, K.5
Deguchi, K.6
Shimizu, Y.7
Bronson, R.T.8
Gao, Y.H.9
Inada, M.10
Sato, M.11
Okamoto, R.12
Kitamura, Y.13
Yoshiki, S.14
Kishimoto, T.15
-
48
-
-
15444351110
-
Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia [see comments]
-
Mundlos S, Otto F, Mundlos C, Mulliken JB, Aylsworth AS, Albright S, Lindhout D, Cole WG, Henn W, Knoll JH, Owen MJ, Mertelsmann R, Zabel BU, Olsen BR., Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia [see comments]. Cell. 1997; 89 (5): 773-9.
-
(1997)
Cell.
, vol.89
, Issue.5
, pp. 773-779
-
-
Mundlos, S.1
Otto, F.2
Mundlos, C.3
Mulliken, J.B.4
Aylsworth, A.S.5
Albright, S.6
Lindhout, D.7
Cole, W.G.8
Henn, W.9
Knoll, J.H.10
Owen, M.J.11
Mertelsmann, R.12
Zabel, B.U.13
Olsen, B.R.14
-
49
-
-
0030666372
-
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development [see comments]
-
Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, Rosewell IR, Stamp GW, Beddington RS, Mundlos S, Olsen BR, Selby PB, Owen MJ., Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development [see comments]. Cell. 1997; 89 (5): 765-71.
-
(1997)
Cell.
, vol.89
, Issue.5
, pp. 765-771
-
-
Otto, F.1
Thornell, A.P.2
Crompton, T.3
Denzel, A.4
Gilmour, K.C.5
Rosewell, I.R.6
Stamp, G.W.7
Beddington, R.S.8
Mundlos, S.9
Olsen, B.R.10
Selby, P.B.11
Owen, M.J.12
-
50
-
-
0032983542
-
Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential
-
Wang D, Christensen K, Chawla K, Xiao G, Krebsbach PH, Franceschi RT., Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential. J Bone Miner Res. 1999; 14 (6): 893-903.
-
(1999)
J Bone Miner Res.
, vol.14
, Issue.6
, pp. 893-903
-
-
Wang, D.1
Christensen, K.2
Chawla, K.3
Xiao, G.4
Krebsbach, P.H.5
Franceschi, R.T.6
-
51
-
-
0030996530
-
Ascorbic acid-dependent activation of the osteocalcin promoter in MC3T3-E1 preosteoblasts: Requirement for collagen matrix synthesis and the presence of an intact OSE2 sequence
-
Xiao G, Cui Y, Ducy P, Karsenty G, Franceschi RT., Ascorbic acid-dependent activation of the osteocalcin promoter in MC3T3-E1 preosteoblasts: requirement for collagen matrix synthesis and the presence of an intact OSE2 sequence. Mol Endocrinol. 1997; 11 (8): 1103-13.
-
(1997)
Mol Endocrinol.
, vol.11
, Issue.8
, pp. 1103-1113
-
-
Xiao, G.1
Cui, Y.2
Ducy, P.3
Karsenty, G.4
Franceschi, R.T.5
-
52
-
-
62449203027
-
Control of HIF-1alpha expression by eIF2 alpha phosphorylation-mediated translational repression
-
Zhu K, Chan W, Heymach J, Wilkinson M, McConkey DJ., Control of HIF-1alpha expression by eIF2 alpha phosphorylation-mediated translational repression. Cancer Res. 2009; 69 (5): 1836-43.
-
(2009)
Cancer Res.
, vol.69
, Issue.5
, pp. 1836-1843
-
-
Zhu, K.1
Chan, W.2
Heymach, J.3
Wilkinson, M.4
McConkey, D.J.5
-
53
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, Burgess T, Elliott R, Colombero A, Elliott G, Scully S, Hsu H, Sullivan J, Hawkins N, Davy E, Capparelli C, Eli A, Qian YX, Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, Delaney J, Boyle WJ., Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell. 1998; 93 (2): 165-76.
-
(1998)
Cell.
, vol.93
, Issue.2
, pp. 165-176
-
-
Lacey, D.L.1
Timms, E.2
Tan, H.L.3
Kelley, M.J.4
Dunstan, C.R.5
Burgess, T.6
Elliott, R.7
Colombero, A.8
Elliott, G.9
Scully, S.10
Hsu, H.11
Sullivan, J.12
Hawkins, N.13
Davy, E.14
Capparelli, C.15
Eli, A.16
Qian, Y.X.17
Kaufman, S.18
Sarosi, I.19
Shalhoub, V.20
Senaldi, G.21
Guo, J.22
Delaney, J.23
Boyle, W.J.24
more..
-
54
-
-
0032584208
-
Osteoclast differentiation factor is a ligand for osteoprotegerin/ osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
-
Yasuda H, Shima N, Nakagawa N, Yamaguchi K, Kinosaki M, Mochizuki S, Tomoyasu A, Yano K, Goto M, Murakami A, Tsuda E, Morinaga T, Higashio K, Udagawa N, Takahashi N, Suda T., Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA. 1998; 95 (7): 3597-602.
-
(1998)
Proc Natl Acad Sci USA.
, vol.95
, Issue.7
, pp. 3597-3602
-
-
Yasuda, H.1
Shima, N.2
Nakagawa, N.3
Yamaguchi, K.4
Kinosaki, M.5
Mochizuki, S.6
Tomoyasu, A.7
Yano, K.8
Goto, M.9
Murakami, A.10
Tsuda, E.11
Morinaga, T.12
Higashio, K.13
Udagawa, N.14
Takahashi, N.15
Suda, T.16
-
55
-
-
0031005576
-
Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
-
Simonet WS, Lacey DL, Dunstan CR, Kelley M, Chang MS, Luthy R, Nguyen HQ, Wooden S, Bennett L, Boone T, Shimamoto G, DeRose M, Elliott R, Colombero A, Tan HL, Trail G, Sullivan J, Davy E, Bucay N, Renshaw-Gegg L, Hughes TM, Hill D, Pattison W, Campbell P, Sander S, Van G, Tarpley J, Derby P, Lee R, Boyle WJ., Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell. 1997; 89 (2): 309-19.
-
(1997)
Cell.
, vol.89
, Issue.2
, pp. 309-319
-
-
Simonet, W.S.1
Lacey, D.L.2
Dunstan, C.R.3
Kelley, M.4
Chang, M.S.5
Luthy, R.6
Nguyen, H.Q.7
Wooden, S.8
Bennett, L.9
Boone, T.10
Shimamoto, G.11
Derose, M.12
Elliott, R.13
Colombero, A.14
Tan, H.L.15
Trail, G.16
Sullivan, J.17
Davy, E.18
Bucay, N.19
Renshaw-Gegg, L.20
Hughes, T.M.21
Hill, D.22
Pattison, W.23
Campbell, P.24
Sander, S.25
Van, G.26
Tarpley, J.27
Derby, P.28
Lee, R.29
Boyle, W.J.30
more..
-
56
-
-
64549134226
-
Real-time imaging of HIF-1alpha stabilization and degradation
-
Moroz E, Carlin S, Dyomina K, Burke S, Thaler HT, Blasberg R, Serganova I., Real-time imaging of HIF-1alpha stabilization and degradation. PLoS One. 2009; 4 (4): e5077.
-
(2009)
PLoS One.
, vol.4
, Issue.4
-
-
Moroz, E.1
Carlin, S.2
Dyomina, K.3
Burke, S.4
Thaler, H.T.5
Blasberg, R.6
Serganova, I.7
-
57
-
-
67650506105
-
TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation
-
Tang Y, Wu X, Lei W, Pang L, Wan C, Shi Z, Zhao L, Nagy TR, Peng X, Hu J, Feng X, Van Hul W, Wan M, Cao X., TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation. Nat Med. 2009; 15 (7): 757-65.
-
(2009)
Nat Med.
, vol.15
, Issue.7
, pp. 757-765
-
-
Tang, Y.1
Wu, X.2
Lei, W.3
Pang, L.4
Wan, C.5
Shi, Z.6
Zhao, L.7
Nagy, T.R.8
Peng, X.9
Hu, J.10
Feng, X.11
Van Hul, W.12
Wan, M.13
Cao, X.14
-
58
-
-
70249108848
-
Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment
-
Dunn LK, Mohammad KS, Fournier PG, McKenna CR, Davis HW, Niewolna M, Peng XH, Chirgwin JM, Guise TA., Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment. PLoS One. 2009; 4 (9): e6896.
-
(2009)
PLoS One.
, vol.4
, Issue.9
-
-
Dunn, L.K.1
Mohammad, K.S.2
Fournier, P.G.3
McKenna, C.R.4
Davis, H.W.5
Niewolna, M.6
Peng, X.H.7
Chirgwin, J.M.8
Guise, T.A.9
-
59
-
-
0015301667
-
Oxygen tension of healing fractures in the rabbit
-
Brighton CT, Krebs AG., Oxygen tension of healing fractures in the rabbit. J Bone Joint Surg Am. 1972; 54 (2): 323-32.
-
(1972)
J Bone Joint Surg Am.
, vol.54
, Issue.2
, pp. 323-332
-
-
Brighton, C.T.1
Krebs, A.G.2
-
60
-
-
31444457128
-
Measurement of oxygen partial pressure in the mandibular bone using a polarographic fine needle probe
-
Maurer P, Meyer L, Eckert AW, Berginski M, Schubert J., Measurement of oxygen partial pressure in the mandibular bone using a polarographic fine needle probe. Int J Oral Maxillofac Surg. 2006; 35 (3): 231-6.
-
(2006)
Int J Oral Maxillofac Surg.
, vol.35
, Issue.3
, pp. 231-236
-
-
Maurer, P.1
Meyer, L.2
Eckert, A.W.3
Berginski, M.4
Schubert, J.5
-
61
-
-
80053565805
-
Human early fracture hematoma is characterized by inflammation and hypoxia
-
Kolar P, Gaber T, Perka C, Duda GN, Buttgereit F., Human early fracture hematoma is characterized by inflammation and hypoxia. Clin Orthop Relat Res. 2011; 469 (11): 3118-26.
-
(2011)
Clin Orthop Relat Res.
, vol.469
, Issue.11
, pp. 3118-3126
-
-
Kolar, P.1
Gaber, T.2
Perka, C.3
Duda, G.N.4
Buttgereit, F.5
|