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Volumn 122, Issue 9, 2012, Pages 3101-3113

Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation

Author keywords

[No Author keywords available]

Indexed keywords

LAMIN A; LAMIN C; NEUTRALIZING ANTIBODY; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; TRANSCRIPTION FACTOR RUNX2; VASCULOTROPIN; VASCULOTROPIN ANTIBODY; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 84866001590     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI61209     Document Type: Article
Times cited : (309)

References (65)
  • 1
    • 0033785920 scopus 로고    scopus 로고
    • Mesenchymal stem cells from osteoporotic patients produce a type I collagen-deficient extracellular matrix favoring adipogenic differentiation
    • Rodríguez JP, Montecinos L, Ríos S, Reyes P, Martínez J. Mesenchymal stem cells from osteoporotic patients produce a type I collagen-deficient extracellular matrix favoring adipogenic differentiation. J Cell Biochem. 2000;79(4):557-565.
    • (2000) J Cell Biochem , vol.79 , Issue.4 , pp. 557-565
    • Rodríguez, J.P.1    Montecinos, L.2    Ríos, S.3    Reyes, P.4    Martínez, J.5
  • 2
    • 0015137446 scopus 로고
    • Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies
    • Meunier P, Aaron J, Edouard C, Vignon G. Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies. Clin Orthop Relat Res. 1971;80:147-154.
    • (1971) Clin Orthop Relat Res , vol.80 , pp. 147-154
    • Meunier, P.1    Aaron, J.2    Edouard, C.3    Vignon, G.4
  • 3
    • 0034842784 scopus 로고    scopus 로고
    • Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis
    • Justesen J, Stenderup K, Ebbesen EN, Mosekilde L, Steiniche T, Kassem M. Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis. Biogerontology. 2001;2(3):165-171.
    • (2001) Biogerontology , vol.2 , Issue.3 , pp. 165-171
    • Justesen, J.1    Stenderup, K.2    Ebbesen, E.N.3    Mosekilde, L.4    Steiniche, T.5    Kassem, M.6
  • 4
    • 0036724870 scopus 로고    scopus 로고
    • Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis
    • Verma S, Rajaratnam JH, Denton J, Hoyland JA, Byers RJ. Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis. J Clin Pathol. 2002;55(9):693-698.
    • (2002) J Clin Pathol , vol.55 , Issue.9 , pp. 693-698
    • Verma, S.1    Rajaratnam, J.H.2    Denton, J.3    Hoyland, J.A.4    Byers, R.J.5
  • 5
    • 22944489618 scopus 로고    scopus 로고
    • Osteoporosis is associated with increased marrow fat content and decreased marrow fat unsaturation: A proton MR spectroscopy study
    • Yeung DK, Griffith JF, Antonio GE, Lee FK, Woo J, Leung PC. Osteoporosis is associated with increased marrow fat content and decreased marrow fat unsaturation: a proton MR spectroscopy study. J Magn Reson Imaging. 2005;22(2):279-285.
    • (2005) J Magn Reson Imaging , vol.22 , Issue.2 , pp. 279-285
    • Yeung, D.K.1    Griffith, J.F.2    Antonio, G.E.3    Lee, F.K.4    Woo, J.5    Leung, P.C.6
  • 6
    • 31544457103 scopus 로고    scopus 로고
    • Mechanisms of disease: Is osteoporosis the obesity of bone?
    • Rosen CJ, Bouxsein ML. Mechanisms of disease: is osteoporosis the obesity of bone? Nat Clin Pract Rheumatol. 2006;2(1):35-43.
    • (2006) Nat Clin Pract Rheumatol , vol.2 , Issue.1 , pp. 35-43
    • Rosen, C.J.1    Bouxsein, M.L.2
  • 7
    • 0026718865 scopus 로고
    • Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures
    • Beresford JN, Bennett JH, Devlin C, Leboy PS, Owen ME. Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures. J Cell Sci. 1992;102(pt 2):341-351.
    • (1992) J Cell Sci , vol.102 , Issue.PART 2 , pp. 341-351
    • Beresford, J.N.1    Bennett, J.H.2    Devlin, C.3    Leboy, P.S.4    Owen, M.E.5
  • 8
    • 2342613539 scopus 로고    scopus 로고
    • Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications
    • Nuttall ME, Gimble JM. Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications. Curr Opin Pharmacol. 2004;4(3):290-294.
    • (2004) Curr Opin Pharmacol , vol.4 , Issue.3 , pp. 290-294
    • Nuttall, M.E.1    Gimble, J.M.2
  • 9
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger MF, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999;284(5411):143-147.
    • (1999) Science , vol.284 , Issue.5411 , pp. 143-147
    • Pittenger, M.F.1
  • 10
    • 0031953736 scopus 로고    scopus 로고
    • Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: Implications for osteopenic disorders
    • Nuttall ME, Patton AJ, Olivera DL, Nadeau DP, Gowen M. Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: implications for osteopenic disorders. J Bone Miner Res. 1998;13(3):371-382.
    • (1998) J Bone Miner Res , vol.13 , Issue.3 , pp. 371-382
    • Nuttall, M.E.1    Patton, A.J.2    Olivera, D.L.3    Nadeau, D.P.4    Gowen, M.5
  • 11
    • 4944257952 scopus 로고    scopus 로고
    • Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow
    • Song L, Tuan RS. Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow. FASEB J. 2004;18(9):980-982.
    • (2004) FASEB J , vol.18 , Issue.9 , pp. 980-982
    • Song, L.1    Tuan, R.S.2
  • 12
    • 46949087543 scopus 로고    scopus 로고
    • Coexpression of osteogenic and adipogenic differentiation markers in selected subpopulations of primary human mesenchymal progenitor cells
    • Ponce ML, et al. Coexpression of osteogenic and adipogenic differentiation markers in selected subpopulations of primary human mesenchymal progenitor cells. J Cell Biochem. 2008;104(4):1342-1355.
    • (2008) J Cell Biochem , vol.104 , Issue.4 , pp. 1342-1355
    • Ponce, M.L.1
  • 13
    • 14744275847 scopus 로고    scopus 로고
    • Regulation of osteoblastogenesis and bone mass by Wnt10b
    • Bennett CN, et al. Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A. 2005;102(9):3324-3329.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.9 , pp. 3324-3329
    • Bennett, C.N.1
  • 14
    • 34347235843 scopus 로고    scopus 로고
    • Wnt signaling stimulates osteoblastogenesis of mesenchymal precursors by suppressing CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma
    • Kang S, Bennett CN, Gerin I, Rapp LA, Hankenson KD, Macdougald OA. Wnt signaling stimulates osteoblastogenesis of mesenchymal precursors by suppressing CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma. J Biol Chem. 2007;282(19):14515-14524.
    • (2007) J Biol Chem , vol.282 , Issue.19 , pp. 14515-14524
    • Kang, S.1    Bennett, C.N.2    Gerin, I.3    Rapp, L.A.4    Hankenson, K.D.5    Macdougald, O.A.6
  • 15
    • 0034637103 scopus 로고    scopus 로고
    • Inhibition of adipogenesis by Wnt signaling
    • Ross SE, et al. Inhibition of adipogenesis by Wnt signaling. Science. 2000;289(5481):950-953.
    • (2000) Science , vol.289 , Issue.5481 , pp. 950-953
    • Ross, S.E.1
  • 16
    • 35748960839 scopus 로고    scopus 로고
    • A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation
    • Takada I, et al. A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation. Nat Cell Biol. 2007;9(11):1273-1285.
    • (2007) Nat Cell Biol , vol.9 , Issue.11 , pp. 1273-1285
    • Takada, I.1
  • 17
    • 77949909802 scopus 로고    scopus 로고
    • Role of WNT-5a in the determination of human mesenchymal stem cells into preadipocytes
    • Bilkovski R, et al. Role of WNT-5a in the determination of human mesenchymal stem cells into preadipocytes. J Biol Chem. 2010;285(9):6170-6178.
    • (2010) J Biol Chem , vol.285 , Issue.9 , pp. 6170-6178
    • Bilkovski, R.1
  • 18
    • 79958171733 scopus 로고    scopus 로고
    • Lrp5 functions in bone to regulate bone mass
    • Cui Y, et al. Lrp5 functions in bone to regulate bone mass. Nat Med. 2011;17(6):684-691.
    • (2011) Nat Med , vol.17 , Issue.6 , pp. 684-691
    • Cui, Y.1
  • 19
    • 74049138304 scopus 로고    scopus 로고
    • Conditional disruption of Pkd1 in osteoblasts results in osteopenia due to direct impairment of bone formation
    • Xiao Z, Zhang S, Cao L, Qiu N, David V, Quarles LD. Conditional disruption of Pkd1 in osteoblasts results in osteopenia due to direct impairment of bone formation. J Biol Chem. 2010;285(2):1177-1187.
    • (2010) J Biol Chem , vol.285 , Issue.2 , pp. 1177-1187
    • Xiao, Z.1    Zhang, S.2    Cao, L.3    Qiu, N.4    David, V.5    Quarles, L.D.6
  • 20
    • 77956516276 scopus 로고    scopus 로고
    • TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells
    • Luo J, et al. TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells. J Biol Chem. 2010;285(38):29588-29598.
    • (2010) J Biol Chem , vol.285 , Issue.38 , pp. 29588-29598
    • Luo, J.1
  • 21
    • 0036192486 scopus 로고    scopus 로고
    • Vascular endothelial growth factor stimulates chemotactic migration of primary human osteoblasts
    • Mayr-Wohlfart U, et al. Vascular endothelial growth factor stimulates chemotactic migration of primary human osteoblasts. Bone. 2002;30(3):472-477.
    • (2002) Bone , vol.30 , Issue.3 , pp. 472-477
    • Mayr-Wohlfart, U.1
  • 22
    • 77955569142 scopus 로고    scopus 로고
    • Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels
    • Maes C, et al. Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels. Dev Cell. 2010;19(2):329-344.
    • (2010) Dev Cell , vol.19 , Issue.2 , pp. 329-344
    • Maes, C.1
  • 23
    • 0038042219 scopus 로고    scopus 로고
    • Adenovirus-mediated VEGFA gene transfer induces bone formation in vivo
    • Hiltunen MO, et al. Adenovirus-mediated VEGFA gene transfer induces bone formation in vivo. FASEB J. 2003;17(9):1147-1149.
    • (2003) FASEB J , vol.17 , Issue.9 , pp. 1147-1149
    • Hiltunen, M.O.1
  • 24
    • 0035093958 scopus 로고    scopus 로고
    • Neuropilin-1 expression in osteogenic cells: Down-regulation during differentiation of osteoblasts into osteocytes
    • Harper J, Gerstenfeld LC, Klagsbrun M. Neuropilin-1 expression in osteogenic cells: down-regulation during differentiation of osteoblasts into osteocytes. J Cell Biochem. 2001;81(1):82-92.
    • (2001) J Cell Biochem , vol.81 , Issue.1 , pp. 82-92
    • Harper, J.1    Gerstenfeld, L.C.2    Klagsbrun, M.3
  • 25
    • 0028237788 scopus 로고
    • Vasculotropin/vascular endothelial growth factor induces differentiation in cultured osteoblasts
    • Midy V, Plouet J. Vasculotropin/vascular endothelial growth factor induces differentiation in cultured osteoblasts. Biochem Biophys Res Commun. 1994;199(1):380-386.
    • (1994) Biochem Biophys Res Commun , vol.199 , Issue.1 , pp. 380-386
    • Midy, V.1    Plouet, J.2
  • 26
    • 0036339867 scopus 로고    scopus 로고
    • Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis
    • Zelzer E, et al. Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development. 2002;129(8):1893-1904.
    • (2002) Development , vol.129 , Issue.8 , pp. 1893-1904
    • Zelzer, E.1
  • 27
    • 0033547805 scopus 로고    scopus 로고
    • Age-dependent impairment of angiogenesis
    • Rivard A, et al. Age-dependent impairment of angiogenesis. Circulation. 1999;99(1):111-120.
    • (1999) Circulation , vol.99 , Issue.1 , pp. 111-120
    • Rivard, A.1
  • 28
    • 4644249816 scopus 로고    scopus 로고
    • Age-dependent VEGF expression and intraneural neovascularization during regeneration of peripheral nerves
    • Pola R, et al. Age-dependent VEGF expression and intraneural neovascularization during regeneration of peripheral nerves. Neurobiol Aging. 2004;25(10):1361-1368.
    • (2004) Neurobiol Aging , vol.25 , Issue.10 , pp. 1361-1368
    • Pola, R.1
  • 29
    • 77950645030 scopus 로고    scopus 로고
    • Agerelated molecular genetic changes of murine bone marrow mesenchymal stem cells
    • Wilson A, Shehadeh LA, Yu H, Webster KA. Agerelated molecular genetic changes of murine bone marrow mesenchymal stem cells. BMC Genomics. 2010;11:229.
    • (2010) BMC Genomics , vol.11 , pp. 229
    • Wilson, A.1    Shehadeh, L.A.2    Yu, H.3    Webster, K.A.4
  • 30
    • 0037022210 scopus 로고    scopus 로고
    • Platelet-derived growth factor-AB limits the extent of myocardial infarction in a rat model: Feasibility of restoring impaired angiogenic capacity in the aging heart
    • Edelberg JM, et al. Platelet-derived growth factor-AB limits the extent of myocardial infarction in a rat model: feasibility of restoring impaired angiogenic capacity in the aging heart. Circulation. 2002;105(5):608-613.
    • (2002) Circulation , vol.105 , Issue.5 , pp. 608-613
    • Edelberg, J.M.1
  • 31
    • 40649113341 scopus 로고    scopus 로고
    • Transcriptional profiling of young and old mesenchymal stem cells in response to oxygen deprivation and reparability of the infarcted myocardium
    • Jiang S, Kh Haider H, Ahmed RP, Idris NM, Salim A, Ashraf M. Transcriptional profiling of young and old mesenchymal stem cells in response to oxygen deprivation and reparability of the infarcted myocardium. J Mol Cell Cardiol. 2008;44(3):582-596.
    • (2008) J Mol Cell Cardiol , vol.44 , Issue.3 , pp. 582-596
    • Jiang, S.1    Kh Haider, H.2    Ahmed, R.P.3    Idris, N.M.4    Salim, A.5    Ashraf, M.6
  • 32
    • 78651422743 scopus 로고    scopus 로고
    • Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning
    • Efimenko A, Starostina E, Kalinina N, Stolzing A. Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning. J Transl Med. 2011;9:10.
    • (2011) J Transl Med , vol.9 , pp. 10
    • Efimenko, A.1    Starostina, E.2    Kalinina, N.3    Stolzing, A.4
  • 33
    • 0033398390 scopus 로고    scopus 로고
    • Impaired wound repair and delayed angiogenesis in aged mice
    • Swift ME, Kleinman HK, DiPietro LA. Impaired wound repair and delayed angiogenesis in aged mice. Lab Invest. 1999;79(12):1479-1487.
    • (1999) Lab Invest , vol.79 , Issue.12 , pp. 1479-1487
    • Swift, M.E.1    Kleinman, H.K.2    DiPietro, L.A.3
  • 34
    • 0037059614 scopus 로고    scopus 로고
    • The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
    • Nakashima K, et al. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002;108(1):17-29.
    • (2002) Cell , vol.108 , Issue.1 , pp. 17-29
    • Nakashima, K.1
  • 37
    • 0033584243 scopus 로고    scopus 로고
    • Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption
    • Niida S, et al. Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption. J Exp Med. 1999;190(2):293-298.
    • (1999) J Exp Med , vol.190 , Issue.2 , pp. 293-298
    • Niida, S.1
  • 38
    • 25444469138 scopus 로고    scopus 로고
    • VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice
    • Niida S, et al. VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice. Proc Natl Acad Sci U S A. 2005;102(39):14016-14021.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.39 , pp. 14016-14021
    • Niida, S.1
  • 39
    • 80052784590 scopus 로고    scopus 로고
    • Retinoblastoma-independent regulation of cell proliferation and senescence by the p53-p21 axis in lamin A/C-depleted cells
    • Moiseeva O, Bourdeau V, Vernier M, Dabauvalle MC, Ferbeyre G. Retinoblastoma-independent regulation of cell proliferation and senescence by the p53-p21 axis in lamin A/C-depleted cells. Aging Cell. 2011;10(5):789-797.
    • (2011) Aging Cell , vol.10 , Issue.5 , pp. 789-797
    • Moiseeva, O.1    Bourdeau, V.2    Vernier, M.3    Dabauvalle, M.C.4    Ferbeyre, G.5
  • 40
    • 58149087318 scopus 로고    scopus 로고
    • Inhibition of lamin A/C attenuates osteoblast differentiation and enhances RANKL-dependent osteoclastogenesis
    • Rauner M, et al. Inhibition of lamin A/C attenuates osteoblast differentiation and enhances RANKL-dependent osteoclastogenesis. J Bone Miner Res. 2009;24(1):78-86.
    • (2009) J Bone Miner Res , vol.24 , Issue.1 , pp. 78-86
    • Rauner, M.1
  • 41
    • 58649084328 scopus 로고    scopus 로고
    • Effect of lamin A/C knockdown on osteoblast differentiation and function
    • Akter R, Rivas D, Geneau G, Drissi H, Duque G. Effect of lamin A/C knockdown on osteoblast differentiation and function. J Bone Miner Res. 2009;24(2):283-293.
    • (2009) J Bone Miner Res , vol.24 , Issue.2 , pp. 283-293
    • Akter, R.1    Rivas, D.2    Geneau, G.3    Drissi, H.4    Duque, G.5
  • 42
    • 84857639761 scopus 로고    scopus 로고
    • Suppression of lamin A/C by short hairpin RNAs promotes adipocyte lineage commitment in mesenchymal progenitor cell line, ROBC26
    • Naito M, Omoteyama K, Mikami Y, Takagi M, Takahashi T. Suppression of lamin A/C by short hairpin RNAs promotes adipocyte lineage commitment in mesenchymal progenitor cell line, ROBC26. Histochem Cell Biol. 2011;137(2):235-247.
    • (2011) Histochem Cell Biol , vol.137 , Issue.2 , pp. 235-247
    • Naito, M.1    Omoteyama, K.2    Mikami, Y.3    Takagi, M.4    Takahashi, T.5
  • 43
    • 32144442169 scopus 로고    scopus 로고
    • Nuclear lamin A inhibits adipocyte differentiation: Implications for Dunnigan-type familial partial lipodystrophy
    • Boguslavsky RL, Stewart CL, Worman HJ. Nuclear lamin A inhibits adipocyte differentiation: implications for Dunnigan-type familial partial lipodystrophy. Hum Mol Genet. 2006;15(4):653-663.
    • (2006) Hum Mol Genet , vol.15 , Issue.4 , pp. 653-663
    • Boguslavsky, R.L.1    Stewart, C.L.2    Worman, H.J.3
  • 44
    • 79955558298 scopus 로고    scopus 로고
    • Decreased bone formation and osteopenia in lamin a/c-deficient mice
    • Li W, et al. Decreased bone formation and osteopenia in lamin a/c-deficient mice. PLoS One. 2011;6(4):e19313.
    • (2011) PLoS One , vol.6 , Issue.4
    • Li, W.1
  • 45
    • 32044457898 scopus 로고    scopus 로고
    • A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C
    • Ivorra C, et al. A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C. Genes Dev. 2006;20(3):307-320.
    • (2006) Genes Dev , vol.20 , Issue.3 , pp. 307-320
    • Ivorra, C.1
  • 46
    • 26444609690 scopus 로고    scopus 로고
    • A-type lamins are essential for TGF-beta1 induced PP2A to dephosphorylate transcription factors
    • Van Berlo JH, et al. A-type lamins are essential for TGF-beta1 induced PP2A to dephosphorylate transcription factors. Hum Mol Genet. 2005;14(19):2839-2849.
    • (2005) Hum Mol Genet , vol.14 , Issue.19 , pp. 2839-2849
    • Van Berlo, J.H.1
  • 47
    • 66849126054 scopus 로고    scopus 로고
    • Lamin complexes in the nuclear interior control progenitor cell proliferation and tissue homeostasis
    • Naetar N, Foisner R. Lamin complexes in the nuclear interior control progenitor cell proliferation and tissue homeostasis. Cell Cycle. 2009;8(10):1488-1493.
    • (2009) Cell Cycle , vol.8 , Issue.10 , pp. 1488-1493
    • Naetar, N.1    Foisner, R.2
  • 48
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
    • Tontonoz P, Hu E, Spiegelman BM. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell. 1994;79(7):1147-1156.
    • (1994) Cell , vol.79 , Issue.7 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 49
    • 67349166515 scopus 로고    scopus 로고
    • Factors regulating circulating vascular endothelial growth factor (VEGF): Association with bone mineral density (BMD) in post-menopausal osteoporosis
    • Costa N, Paramanathan S, Mac Donald D, Wierzbicki AS, Hampson G. Factors regulating circulating vascular endothelial growth factor (VEGF): association with bone mineral density (BMD) in post-menopausal osteoporosis. Cytokine. 2009;46(3):376-381.
    • (2009) Cytokine , vol.46 , Issue.3 , pp. 376-381
    • Costa, N.1    Paramanathan, S.2    Mac Donald, D.3    Wierzbicki, A.S.4    Hampson, G.5
  • 50
    • 0037182861 scopus 로고    scopus 로고
    • VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
    • Gerber HP, et al. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Nature. 2002;417(6892):954-958.
    • (2002) Nature , vol.417 , Issue.6892 , pp. 954-958
    • Gerber, H.P.1
  • 51
    • 34547941252 scopus 로고    scopus 로고
    • Autocrine VEGF signaling is required for vascular homeostasis
    • Lee S, et al. Autocrine VEGF signaling is required for vascular homeostasis. Cell. 2007;130(4):691-703.
    • (2007) Cell , vol.130 , Issue.4 , pp. 691-703
    • Lee, S.1
  • 52
    • 79952534370 scopus 로고    scopus 로고
    • Intracrine vascular endothelial growth factor signaling in survival and chemoresistance of human colorectal cancer cells
    • Samuel S, Fan F, Dang LH, Xia L, Gaur P, Ellis LM. Intracrine vascular endothelial growth factor signaling in survival and chemoresistance of human colorectal cancer cells. Oncogene. 2011;30(10):1205-1212.
    • (2011) Oncogene , vol.30 , Issue.10 , pp. 1205-1212
    • Samuel, S.1    Fan, F.2    Dang, L.H.3    Xia, L.4    Gaur, P.5    Ellis, L.M.6
  • 53
    • 34347205690 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internaly expressed VEGFR1/FLT1
    • Lee T-H, et al. Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internaly expressed VEGFR1/FLT1. PLoS Med. 2007;4(6):e186.
    • (2007) PLoS Med , vol.4 , Issue.6
    • Lee, T.-H.1
  • 54
    • 0034065028 scopus 로고    scopus 로고
    • VEGF nuclear accumulation correlates with phenotypical changes in endothelial cells
    • Li W, Keller G. VEGF nuclear accumulation correlates with phenotypical changes in endothelial cells. J Cell Sci. 2000;113(pt 9):1525-1534.
    • (2000) J Cell Sci , vol.113 , Issue.PART 9 , pp. 1525-1534
    • Li, W.1    Keller, G.2
  • 56
    • 59149094516 scopus 로고    scopus 로고
    • Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats)
    • Zhang Y, et al. Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats). J Biol Chem. 2009;284(5):3125-3135.
    • (2009) J Biol Chem , vol.284 , Issue.5 , pp. 3125-3135
    • Zhang, Y.1
  • 57
    • 80054966662 scopus 로고    scopus 로고
    • Physical and functional interactions between Runx2 and HIF-1alpha induce vascular endothelial growth factor gene expression
    • Kwon TG, et al. Physical and functional interactions between Runx2 and HIF-1alpha induce vascular endothelial growth factor gene expression. J Cell Biochem. 2011;112(12):3582-3593.
    • (2011) J Cell Biochem , vol.112 , Issue.12 , pp. 3582-3593
    • Kwon, T.G.1
  • 59
    • 34249913494 scopus 로고    scopus 로고
    • The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development
    • Wang Y, et al. The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. J Clin Invest. 2007;117(6):1616-1626.
    • (2007) J Clin Invest , vol.117 , Issue.6 , pp. 1616-1626
    • Wang, Y.1
  • 60
    • 43149112035 scopus 로고    scopus 로고
    • Interaction between human umbilical vein endothelial cells and human osteoprogenitors triggers pleiotropic effect that may support osteoblastic function
    • Guillotin B, Bareille R, Bourget C, Bordenave L, Amedee J. Interaction between human umbilical vein endothelial cells and human osteoprogenitors triggers pleiotropic effect that may support osteoblastic function. Bone. 2008;42(6):1080-1091.
    • (2008) Bone , vol.42 , Issue.6 , pp. 1080-1091
    • Guillotin, B.1    Bareille, R.2    Bourget, C.3    Bordenave, L.4    Amedee, J.5
  • 61
    • 0032931234 scopus 로고    scopus 로고
    • VEGF is required for growth and survival in neonatal mice
    • Gerber HP, et al. VEGF is required for growth and survival in neonatal mice. Development. 1999;126(6):1149-1159.
    • (1999) Development , vol.126 , Issue.6 , pp. 1149-1159
    • Gerber, H.P.1
  • 62
    • 33748768971 scopus 로고    scopus 로고
    • Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors
    • Rodda SJ, McMahon AP. Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors. Development. 2006;133(16):3231-3244.
    • (2006) Development , vol.133 , Issue.16 , pp. 3231-3244
    • Rodda, S.J.1    McMahon, A.P.2
  • 63
    • 0023488581 scopus 로고
    • Bone histomorphometry: Standardization of nomenclature, symbols, and units
    • Report of the ASBMR Histomorphometry Nomenclature Committee
    • Parfitt AM, et al. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res. 1987;2(6):595-610.
    • (1987) J Bone Miner Res , vol.2 , Issue.6 , pp. 595-610
    • Parfitt, A.M.1
  • 64
    • 0038049138 scopus 로고    scopus 로고
    • Osteoblast isolation from murine calvariae and long bones
    • Bakker A, Klein-Nulend J. Osteoblast isolation from murine calvariae and long bones. Methods Mol Med. 2003;80:19-28.
    • (2003) Methods Mol Med , vol.80 , pp. 19-28
    • Bakker, A.1    Klein-Nulend, J.2
  • 65


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.