메뉴 건너뛰기




Volumn 91, Issue 5, 2013, Pages 1991-2000

Digestive physiology of the pig symposium: Intestinal bile acid sensing is linked to key endocrine and metabolic signaling pathways

Author keywords

Enteroendocrine; Farnesoid X receptor; Fibroblast growth factor 19; G protein coupled bile acid receptor 1 TGR5; Glucagon like peptide 1; Glucagon like peptide 2

Indexed keywords


EID: 84882570594     PISSN: 00218812     EISSN: 15253163     Source Type: Journal    
DOI: 10.2527/jas.2013-6331     Document Type: Article
Times cited : (51)

References (70)
  • 1
    • 0020595095 scopus 로고
    • The role of pancreatico-biliary secretions in intestinal adaptation after resection, and its relationship to plasma enteroglucagon
    • Al-Mukhtar, M. Y., G. R. Sagor, M. A. Ghatei, S. R. Bloom, and N. A. Wright. 1983. The role of pancreatico-biliary secretions in intestinal adaptation after resection, and its relationship to plasma enteroglucagon. Br. J. Surg. 70:398-400.
    • (1983) Br. J. Surg , vol.70 , pp. 398-400
    • Al-Mukhtar, M.Y.1    Sagor, G.R.2    Ghatei, M.A.3    Bloom, S.R.4    Wright, N.A.5
  • 2
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1 and GIP
    • Baggio, L. L., and D. J. Drucker. 2007. Biology of incretins: GLP-1 and GIP. Gastroenterology 132:2131-2157.
    • (2007) Gastroenterology , vol.132 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.J.2
  • 4
    • 80052049014 scopus 로고    scopus 로고
    • GLP-1 and energy balance: An integrated model of shortterm and long-term control
    • Barrera, J. G., D. A. Sandoval, D. A. D'Alessio, and R. J. Seeley. 2011. GLP-1 and energy balance: An integrated model of shortterm and long-term control. Nat. Rev. Endocrinol. 7:507-516.
    • (2011) Nat. Rev. Endocrinol , vol.7 , pp. 507-516
    • Barrera, J.G.1    Sandoval, D.A.2    D'Alessio, D.A.3    Seeley, R.J.4
  • 5
    • 84856701167 scopus 로고    scopus 로고
    • Effect of bile acid sequestrants on glucose metabolism, hepatic de novo lipogenesis, and cholesterol and bile acid kinetics in type 2 diabetes: A randomised controlled study
    • Beysen, C., E. J. Murphy, K. Deines, M. Chan, E. Tsang, A. Glass, S. M. Turner, J. Protasio, T. Riiff, and M. K. Hellerstein. 2012. Effect of bile acid sequestrants on glucose metabolism, hepatic de novo lipogenesis, and cholesterol and bile acid kinetics in type 2 diabetes: A randomised controlled study. Diabetologia 55:432-442.
    • (2012) Diabetologia , vol.55 , pp. 432-442
    • Beysen, C.1    Murphy, E.J.2    Deines, K.3    Chan, M.4    Tsang, E.5    Glass, A.6    Turner, S.M.7    Protasio, J.8    Riiff, T.9    Hellerstein, M.K.10
  • 6
    • 0037370995 scopus 로고    scopus 로고
    • Glucagon-like peptide 2 function in domestic animals
    • Burrin, D. G., B. Stoll, and X. Guan. 2003. Glucagon-like peptide 2 function in domestic animals. Domest. Anim. Endocrinol. 24:103-122.
    • (2003) Domest. Anim. Endocrinol , vol.24 , pp. 103-122
    • Burrin, D.G.1    Stoll, B.2    Guan, X.3
  • 11
    • 77954660699 scopus 로고    scopus 로고
    • Getting the mOST from OST: Role of organic solute transporter, OSTalpha-OSTbeta, in bile acid and steroid metabolism
    • Dawson, P. A., M. L. Hubbert, and A. Rao. 2010. Getting the mOST from OST: Role of organic solute transporter, OSTalpha-OSTbeta, in bile acid and steroid metabolism. Biochim. Biophys. Acta 1801:994-1004.
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 994-1004
    • Dawson, P.A.1    Hubbert, M.L.2    Rao, A.3
  • 12
    • 33745771673 scopus 로고    scopus 로고
    • Biologic actions and therapeutic potential of the proglucagon-derived peptides
    • Drucker, D. J. 2005. Biologic actions and therapeutic potential of the proglucagon-derived peptides. Nat. Clin. Pract. Endocrinol. Metab. 1:22-31.
    • (2005) Nat. Clin. Pract. Endocrinol. Metab , vol.1 , pp. 22-31
    • Drucker, D.J.1
  • 13
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones
    • Drucker, D. J. 2006. The biology of incretin hormones. Cell Metab. 3:153-165.
    • (2006) Cell Metab , vol.3 , pp. 153-165
    • Drucker, D.J.1
  • 14
    • 12244271085 scopus 로고    scopus 로고
    • Nutrient, neural and endocrine control of glucagon-like peptide secretion
    • Dube, P. E., and P. L. Brubaker. 2004. Nutrient, neural and endocrine control of glucagon-like peptide secretion. Horm. Metab. Res. 36:755-760.
    • (2004) Horm. Metab. Res , vol.36 , pp. 755-760
    • Dube, P.E.1    Brubaker, P.L.2
  • 16
  • 19
    • 70350292362 scopus 로고    scopus 로고
    • Bileacid-activated receptors: Targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders
    • Fiorucci, S., A. Mencarelli, G. Palladino, and S. Cipriani. 2009. Bileacid-activated receptors: Targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders. Trends Pharmacol. Sci. 30:570-580.
    • (2009) Trends Pharmacol. Sci , vol.30 , pp. 570-580
    • Fiorucci, S.1    Mencarelli, A.2    Palladino, G.3    Cipriani, S.4
  • 21
    • 84868192541 scopus 로고    scopus 로고
    • The role of the gut hormone GLP-1 in the metabolic improvements caused by ileal transposition
    • Gaitonde, S., R. Kohli, and R. Seeley. 2012. The role of the gut hormone GLP-1 in the metabolic improvements caused by ileal transposition. J. Surg. Res. 178:33-39.
    • (2012) J. Surg. Res , vol.178 , pp. 33-39
    • Gaitonde, S.1    Kohli, R.2    Seeley, R.3
  • 22
    • 74849119709 scopus 로고    scopus 로고
    • Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: Potential impact in diabetes
    • Genet, C., A. Strehle, C. Schmidt, G. Boudjelal, A. Lobstein, K. Schoonjans, M. Souchet, J. Auwerx, R. Saladin, and A. Wagner. 2010. Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: Potential impact in diabetes. J. Med. Chem. 53:178-190.
    • (2010) J. Med. Chem , vol.53 , pp. 178-190
    • Genet, C.1    Strehle, A.2    Schmidt, C.3    Boudjelal, G.4    Lobstein, A.5    Schoonjans, K.6    Souchet, M.7    Auwerx, J.8    Saladin, R.9    Wagner, A.10
  • 23
    • 50249180215 scopus 로고    scopus 로고
    • Bile acids: Chemistry, pathochemistry, biology, pathobiology, and therapeutics
    • Hofmann, A. F., and L. R. Hagey. 2008. Bile acids: Chemistry, pathochemistry, biology, pathobiology, and therapeutics. Cell Mol. Life Sci. 65:2461-2483.
    • (2008) Cell Mol. Life Sci , vol.65 , pp. 2461-2483
    • Hofmann, A.F.1    Hagey, L.R.2
  • 24
    • 82555189369 scopus 로고    scopus 로고
    • Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus: Focus on bile acid sequestrants
    • Holst, J. J., and M. A. McGill. 2012. Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus: Focus on bile acid sequestrants. Clin. Drug Investig. 32:1-14.
    • (2012) Clin. Drug Investig , vol.32 , pp. 1-14
    • Holst, J.J.1    McGill, M.A.2
  • 25
    • 34948821192 scopus 로고    scopus 로고
    • FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver
    • Huang, X., C. Yang, Y. Luo, C. Jin, F. Wang, and W. L. McKeehan. 2007. FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver. Diabetes 56:2501-2510.
    • (2007) Diabetes , vol.56 , pp. 2501-2510
    • Huang, X.1    Yang, C.2    Luo, Y.3    Jin, C.4    Wang, F.5    McKeehan, W.L.6
  • 26
    • 84855334407 scopus 로고    scopus 로고
    • Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs
    • Jain, A. K., B. Stoll, D. G. Burrin, J. J. Holst, and D. D. Moore. 2012. Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs. Am. J. Physiol. Gastrointest. Liver Physiol. 302:G218-G224.
    • (2012) Am. J. Physiol. Gastrointest. Liver Physiol , vol.302
    • Jain, A.K.1    Stoll, B.2    Burrin, D.G.3    Holst, J.J.4    Moore, D.D.5
  • 28
    • 37249015421 scopus 로고    scopus 로고
    • Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine
    • Kim, I., S. H. Ahn, T. Inagaki, M. Choi, S. Ito, G. L. Guo, S. A. Kliewer, and F. J. Gonzalez. 2007. Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine. J. Lipid Res. 48:2664-2672.
    • (2007) J. Lipid Res , vol.48 , pp. 2664-2672
    • Kim, I.1    Ahn, S.H.2    Inagaki, T.3    Choi, M.4    Ito, S.5    Guo, G.L.6    Kliewer, S.A.7    Gonzalez, F.J.8
  • 29
    • 70350380343 scopus 로고    scopus 로고
    • Duodenal-jejunal exclusion improves glucose tolerance in the diabetic, Goto-Kakizaki rat by a GLP-1 receptor-mediated mechanism
    • Kindel, T. L., S. M. Yoder, R. J. Seeley, D. A. D'Alessio, and P. Tso. 2009. Duodenal-jejunal exclusion improves glucose tolerance in the diabetic, Goto-Kakizaki rat by a GLP-1 receptor-mediated mechanism. J. Gastrointest. Surg. 13:1762-1772.
    • (2009) J. Gastrointest. Surg , vol.13 , pp. 1762-1772
    • Kindel, T.L.1    Yoder, S.M.2    Seeley, R.J.3    D'Alessio, D.A.4    Tso, P.5
  • 31
    • 49649118142 scopus 로고    scopus 로고
    • Endocrine FGFs and Klothos: Emerging concepts
    • Kuro-O, M. 2008. Endocrine FGFs and Klothos: Emerging concepts.Trends Endocrinol. Metab. 19:239-245.
    • (2008) Trends Endocrinol. Metab , vol.19 , pp. 239-245
    • Kuro-O, M.1
  • 32
    • 84863986239 scopus 로고    scopus 로고
    • Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism
    • Lan, T., A. Rao, J. Haywood, N. D. Kock, and P. A. Dawson. 2012. Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism. J. Hepatol. 57:359-365.
    • (2012) J. Hepatol , vol.57 , pp. 359-365
    • Lan, T.1    Rao, A.2    Haywood, J.3    Kock, N.D.4    Dawson, P.A.5
  • 34
    • 58249110568 scopus 로고    scopus 로고
    • Role of bile acids and bile acid receptors in metabolic regulation
    • Lefebvre, P., B. Cariou, F. Lien, F. Kuipers, and B. Staels. 2009. Role of bile acids and bile acid receptors in metabolic regulation. Physiol. Rev. 89:147-191.
    • (2009) Physiol. Rev , vol.89 , pp. 147-191
    • Lefebvre, P.1    Cariou, B.2    Lien, F.3    Kuipers, F.4    Staels, B.5
  • 36
    • 67651173077 scopus 로고    scopus 로고
    • Incretin-based therapies for type 2 diabetes mellitus
    • Lovshin, J. A., and D. J. Drucker. 2009. Incretin-based therapies for type 2 diabetes mellitus. Nat. Rev. Endocrinol. 5:262-269.
    • (2009) Nat. Rev. Endocrinol , vol.5 , pp. 262-269
    • Lovshin, J.A.1    Drucker, D.J.2
  • 37
    • 33751115468 scopus 로고    scopus 로고
    • Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man
    • Lundasen, T., C. Galman, B. Angelin, and M. Rudling. 2006. Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man. J. Intern. Med. 260:530-536.
    • (2006) J. Intern. Med , vol.260 , pp. 530-536
    • Lundasen, T.1    Galman, C.2    Angelin, B.3    Rudling, M.4
  • 38
  • 39
    • 77952674868 scopus 로고    scopus 로고
    • The bile acid sensor farnesoid X receptor is a modulator of liver immunity in a rodent model of acute hepatitis
    • Mencarelli, A., B. Renga, M. Migliorati, S. Cipriani, E. Distrutti, L. Santucci, and S. Fiorucci. 2009. The bile acid sensor farnesoid X receptor is a modulator of liver immunity in a rodent model of acute hepatitis. J. Immunol. 183:6657-6666.
    • (2009) J. Immunol , vol.183 , pp. 6657-6666
    • Mencarelli, A.1    Renga, B.2    Migliorati, M.3    Cipriani, S.4    Distrutti, E.5    Santucci, L.6    Fiorucci, S.7
  • 43
    • 83755220083 scopus 로고    scopus 로고
    • Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion
    • Parker, H. E., K. Wallis, C. W. le Roux, K. Y. Wong, F. Reimann, and F. M. Gribble. 2012. Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion. Br. J. Pharmacol. 165:414-423.
    • (2012) Br. J. Pharmacol , vol.165 , pp. 414-423
    • Parker, H.E.1    Wallis, K.2    le Roux, C.W.3    Wong, K.Y.4    Reimann, F.5    Gribble, F.M.6
  • 45
    • 4143056853 scopus 로고    scopus 로고
    • Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid
    • Pellicciari, R., G. Costantino, E. Camaioni, B. M. Sadeghpour, A. Entrena, T. M. Willson, S. Fiorucci, C. Clerici, and A. Gioiello. 2004. Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid. J. Med. Chem. 47:4559-4569.
    • (2004) J. Med. Chem , vol.47 , pp. 4559-4569
    • Pellicciari, R.1    Costantino, G.2    Camaioni, E.3    Sadeghpour, B.M.4    Entrena, A.5    Willson, T.M.6    Fiorucci, S.7    Clerici, C.8    Gioiello, A.9
  • 47
    • 84857185764 scopus 로고    scopus 로고
    • Endocrine fibroblast growth factors 15/19 and 21: From feast to famine
    • Potthoff, M. J., S. A. Kliewer, and D. J. Mangelsdorf. 2012. Endocrine fibroblast growth factors 15/19 and 21: From feast to famine. Genes Dev. 26:312-324.
    • (2012) Genes Dev , vol.26 , pp. 312-324
    • Potthoff, M.J.1    Kliewer, S.A.2    Mangelsdorf, D.J.3
  • 50
    • 0020572789 scopus 로고
    • Adaptation and carcinogenesis in defunctioned rat colon: Divergent effects of faeces and bile acids
    • Rainey, J. B., P. W. Davies, J. B. Bristol, and R. C. Williamson. 1983. Adaptation and carcinogenesis in defunctioned rat colon: Divergent effects of faeces and bile acids. Br. J. Cancer 48:477-484.
    • (1983) Br. J. Cancer , vol.48 , pp. 477-484
    • Rainey, J.B.1    Davies, P.W.2    Bristol, J.B.3    Williamson, R.C.4
  • 51
    • 84990627050 scopus 로고
    • The tropic effect of intrarectal deoxycholate on rat colorectum is unaffected by oral metronidazole
    • Rainey, J. B., M. Maeda, and R. C. Williamson. 1986. The tropic effect of intrarectal deoxycholate on rat colorectum is unaffected by oral metronidazole. Cell Tissue Kinet. 19:485-490.
    • (1986) Cell Tissue Kinet , vol.19 , pp. 485-490
    • Rainey, J.B.1    Maeda, M.2    Williamson, R.C.3
  • 52
    • 73949160857 scopus 로고    scopus 로고
    • Gut chemosensing: Interactions between gut endocrine cells and visceral afferents
    • Raybould, H. E. 2010. Gut chemosensing: Interactions between gut endocrine cells and visceral afferents. Auton. Neurosci. 153:41-46.
    • (2010) Auton. Neurosci , vol.153 , pp. 41-46
    • Raybould, H.E.1
  • 57
  • 58
    • 84871694003 scopus 로고    scopus 로고
    • Fibroblast growth factor-19 action in the brain reduces food intake and body weight and improves glucose tolerance in male rats
    • Ryan, K. K., R. Kohli, R. Gutierrez-Aguilar, S. G. Gaitonde, S. C. Woods, and R. J. Seeley. 2013. Fibroblast growth factor-19 action in the brain reduces food intake and body weight and improves glucose tolerance in male rats. Endocrinology 154:9-15.
    • (2013) Endocrinology , vol.154 , pp. 9-15
    • Ryan, K.K.1    Kohli, R.2    Gutierrez-Aguilar, R.3    Gaitonde, S.G.4    Woods, S.C.5    Seeley, R.J.6
  • 59
    • 0023936558 scopus 로고
    • Experimental colonic carcinogenesis: Changes in faecal bile acids after promotion of intestinal tumours by small bowel resection in the rat
    • Savage, A. P., M. S. Sian, J. L. Matthews, S. R. Bloom, and T. Cooke. 1988. Experimental colonic carcinogenesis: Changes in faecal bile acids after promotion of intestinal tumours by small bowel resection in the rat. Gut 29:495-502.
    • (1988) Gut , vol.29 , pp. 495-502
    • Savage, A.P.1    Sian, M.S.2    Matthews, J.L.3    Bloom, S.R.4    Cooke, T.5
  • 61
    • 77249142314 scopus 로고    scopus 로고
    • Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1
    • Shang, Q., M. Saumoy, J. J. Holst, G. Salen, and G. Xu. 2010. Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1. Am. J. Physiol. Gastrointest. Liver Physiol. 298:G419-G424.
    • (2010) Am. J. Physiol. Gastrointest. Liver Physiol , vol.298
    • Shang, Q.1    Saumoy, M.2    Holst, J.J.3    Salen, G.4    Xu, G.5
  • 67
    • 0014242412 scopus 로고
    • Characterization of the responses of circulating glucagonlike immunoreactivity to intraduodenal and intravenous administration of glucose
    • Unger, R. H., A. Ohneda, I. Valverde, A. M. Eisentraut, and J. Exton. 1968. Characterization of the responses of circulating glucagonlike immunoreactivity to intraduodenal and intravenous administration of glucose. J. Clin. Invest. 47:48-65.
    • (1968) J. Clin. Invest , vol.47 , pp. 48-65
    • Unger, R.H.1    Ohneda, A.2    Valverde, I.3    Eisentraut, A.M.4    Exton, J.5
  • 68
    • 0035090367 scopus 로고    scopus 로고
    • Secretion of trophic gut peptides is not different in bolus- and continuously fed piglets
    • van Goudoever, J. B., B. Stoll, B. Hartmann, J. J. Holst, P. J. Reeds, and D. G. Burrin. 2001. Secretion of trophic gut peptides is not different in bolus- and continuously fed piglets. J. Nutr. 131:729-732.
    • (2001) J. Nutr , vol.131 , pp. 729-732
    • van Goudoever, J.B.1    Stoll, B.2    Hartmann, B.3    Holst, J.J.4    Reeds, P.J.5    Burrin, D.G.6
  • 69
    • 0033026760 scopus 로고    scopus 로고
    • Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
    • Wang, H., J. Chen, K. Hollister, L. C. Sowers, and B. M. Forman. 1999. Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol. Cell 3:543-553.
    • (1999) Mol. Cell , vol.3 , pp. 543-553
    • Wang, H.1    Chen, J.2    Hollister, K.3    Sowers, L.C.4    Forman, B.M.5
  • 70
    • 0033028489 scopus 로고    scopus 로고
    • Secretion of the intestinotropic hormone glucagon-like peptide 2 is differentially regulated by nutrients in humans
    • Xiao, Q., R. P. Boushey, D. J. Drucker, and P. L. Brubaker. 1999. Secretion of the intestinotropic hormone glucagon-like peptide 2 is differentially regulated by nutrients in humans. Gastroenterology 117:99-105.
    • (1999) Gastroenterology , vol.117 , pp. 99-105
    • Xiao, Q.1    Boushey, R.P.2    Drucker, D.J.3    Brubaker, P.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.