Secretion of the intestinotropic hormone glucagon-like peptide 2 is differentially regulated by nutrients in humans

Gastroenterology

Volumn 117, Issue 1, 1999, Pages 99-105

  Xiao, Q ^a   Boushey, R P ^a   Drucker, D J ^a   Brubaker, P L ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON LIKE PEPTIDE;

ADULT; ARTICLE; CARBOHYDRATE DIET; CONTROLLED STUDY; EATING; HORMONE BLOOD LEVEL; HORMONE DETERMINATION; HORMONE RELEASE; HUMAN; HUMAN EXPERIMENT; LIPID DIET; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DIET; REGULATORY MECHANISM;

EID: 0033028489     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(99)70555-X     Document Type: Article

References (35)

1. S Mojsov G Heinrich IB Wilson M Ravazzola L Orci JF Habener Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing J Biol Chem 261 1986 11880 11889
2. C Orskov JJ Holst Radio-immunoassays for glucagon-like peptides 1 and 2 (GLP-1 and GLP-2) Scand J Gastroenterol 47 1987 165 174
3. S Dhanvantari NG Seidah PL Brubaker Role of prohormone convertases in the tissue-specific processing of proglucagon Mol Endocrinol 10 1996 342 355
4. PL Brubaker A Crivici A Izzo P Ehrlich CH Tsai DJ Drucker Circulating and tissue forms of the intestinal growth factor, glucagon-like peptide-2 Endocrinology 138 1997 4837 4843
5. DJ Drucker Q Shi A Crivici M Sumner-Smith W Tavares M Hill L DeForest S Cooper PL Brubaker Regulation of the biological activity of glucagon-like peptide 2 in vivo by dipeptidyl peptidase IV Nat Biotechnol 15 1997 673 677
6. W Tavares PL Brubaker In vivo metabolism and clearance of the intestinal growth factor glucagon-like peptide-2 (abstr) Endocrine Society P3 1998 346
7. PJ Lefèbvre Glucagon and its family revisited Diabetes Care 18 1995 715 730
8. DJ Drucker Glucagon-like peptides Diabetes 47 1998 159 169
9. DJ Drucker P Ehrlich SL Asa PL Brubaker Induction of intestinal epithelial proliferation by glucagon-like peptide 2 Proc Natl Acad Sci USA 93 1996 7911 7916
10. CH Tsai M Hill SL Asa PL Brubaker DJ Drucker Intestinal growth-promoting properties of glucagon-like peptide-2 in mice Am J Physiol Endocrinol Metab 273 1997 E77 E84
11. DA Litvak MR Hellmich M Evers NA Banker CM Townsend Jr Glucagon-like peptide 2 is a potent growth factor for small intestine and colon J Gastrointest Surg 2 1998 146 150
12. DJ Drucker B Yusta R Boushey L DeForest PL Brubaker Human [Gly2]-GLP-2 reduces the severity of colonic injury in a murine model of experimental colitis Am J Physiol Gastrointest Liver Physiol 276 1999 G79 G91
13. PL Brubaker A Izzo M Hill DJ Drucker Intestinal function in mice with small bowel growth induced by glucagon-like peptide-2 Am J Physiol Endocrinol Metab 272 1997 E1050 E1058
14. CI Cheeseman Upregulation of SGLT-1 transport activity in rat jejunum induced by GLP-2 infusion in vivo Am J Physiol Regul Integr Comp Physiol 273 1997 R1965 R1971
15. RB Scott D Kirk WK MacNaughton JB Meddings GLP-2 augments the adaptive response to massive intestinal resection in rat Am J Physiol Gastrointest Liver Physiol 275 1998 G911 G921
16. M Wojdemann A Wettergren B Hartmann JJ Holst Glucagon-like peptide-2 inhibits centrally induced antral motility in pigs Scand J Gastroenterol 33 1998 828 832
17. WT Chance T Foley-Nelson I Thomas A Balasubramaniam Prevention of parenteral nutrition-induced gut hypoplasia by coinfusion of glucagon-like peptide-2 Am J Physiol 273 1997 G559 G563
18. KD Fischer S Dhanvantari DJ Drucker PL Brubaker Intestinal growth is associated with elevated levels of glucagon-like peptide-2 in diabetic rats Am J Physiol Endocrinol Metab 273 1997 E815 E820
19. D D'Alessio R Thirlby E Laschansky H Zebroski J Ensinck Response of tGLP-1 to nutrients in humans Digestion 54 1993 377 379
20. RM Elliott LM Morgan JA Tredger S Deacon J Wright V Marks Glucagon-like peptide-1(7-36) amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-hour secretion patterns J Endocrinol 138 1993 159 166
21. C Herrmann R Göke G Richter H-C Fehmann R Arnold B Göke Glucagon-like peptide-1 and glucose-dependent insulin–releasing polypeptide plasma levels in response to nutrients Digestion 56 1995 117 126
22. C Orskov JJ Holst S Knuhtsen FGA Baldissera SS Poulsen OV Nielsen Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas Endocrinology 119 1986 1467 1475
23. P Layer JJ Holst D Grandt H Goebell Ileal release of glucagon-like peptide-1 (GLP-1): association with inhibition of gastric acid secretion in humans Dig Dis Sci 40 1995 1074 1082
24. G Bottcher K Sjolund E Ekblad R Hakanson TW Schwartz F Sundler Coexistence of peptide YY and glicentin immunoreactivity in endocrine cells of the gut Regul Pept 8 1984 261 266
25. C Ruiz-Grande J Pintado C Alarcón C Castilla I Valverde JM López-Novoa Renal catabolism of human glucagon-like peptides 1 and 2 Can J Physiol Pharmacol 68 1990 1568 1573
26. JN Roberge PL Brubaker Regulation of intestinal proglucagon-derived peptide secretion by glucose-dependent insulinotropic peptide in a novel enteroendocrine loop Endocrinology 133 1993 233 240
27. AS Rocca PL Brubaker Stereospecific effects of fatty acids on proglucagon-derived peptide secretion in fetal rat intestinal cultures Endocrinology 136 1995 5593 5599
28. M Cordier-Bussat C Bernard F Levenez N Klages B Laser-Ritz J Philippe JA Chayvialle JC Cuber Peptones stimulate both the secretion of the incretin hormone glucagon-like peptide 1 and the transcription of the proglucagon gene Diabetes 47 1998 1038 1045
29. J Schirra M Katschinski C Weidmann T Schäfer U Wank R Arnold B Göke Gastric emptying and release of incretin hormones after glucose ingestion in humans J Clin Invest 97 1996 92 103
30. JN Roberge KA Gronau PL Brubaker Gastrin-releasing peptide is a novel mediator of proximal nutrient-induced proglucagon-derived peptide secretion from the distal gut Endocrinology 137 1996 2383 2388
31. AS Rocca PL Brubaker Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion Endocrinology 140 1999 1687 1694
32. GH Greeley Jr. Y-J Jeng G Gomez T Hashimoto FLC Hill K Kern T Kurosky H-F Chuo JC Thompson Evidence for regulation of peptide-YY release by the proximal gut Endocrinology 124 1989 1438 1443
33. RA Liddle Cholecystokinin cells Annu Rev Physiol 59 1997 221 242
34. Y Li C Owyang Peptone stimulates CCK-releasing peptide secretion by activating intestinal submucosal chonergic neurons J Clin Invest 97 1996 1463 1470
35. P Rorsman FM Ashcroft P-O Berggren Regulation of glucagon release from pancreatic A-cells Biochem Pharmacol 41 1991 1783 1790