Molecular regulation of CCN2 in the intervertebral disc: Lessons learned from other connective tissues

Matrix Biology

Volumn 32, Issue 6, 2013, Pages 298-306

  Tran, Cassie M ^a   Shapiro, Irving M ^a   Risbud, Makarand V ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

CCN2; Disc degeneration; HIF 1 ; Hypoxia; Inflammatory cytokines; Intervertebral disc; Nucleus pulposus; TGF

Indexed keywords

BETA CATENIN; CONNECTIVE TISSUE GROWTH FACTOR; ENDOTHELIN 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMAD1 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA;

3' UNTRANSLATED REGION; ARTICULAR CARTILAGE; BIOMECHANICS; CARTILAGE CELL; CELL DIFFERENTIATION; CELL POPULATION; CONNECTIVE TISSUE; EXTRACELLULAR MATRIX; GENETIC TRANSCRIPTION; HUMAN; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; MECHANICAL STRESS; MESANGIUM CELL; MESODERM; MICROENVIRONMENT; NONHUMAN; NOTOCHORD; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RANGE OF MOTION; REGULATORY MECHANISM; SHORT SURVEY; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION SITE;

EID: 84882569203     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2013.03.006     Document Type: Short Survey

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