메뉴 건너뛰기




Volumn 50, Issue 3, 2009, Pages 939-947

Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA ACTIN; CARBON TETRACHLORIDE; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; CONNECTIVE TISSUE GROWTH FACTOR; GELATINASE A; HYALURONIC ACID; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; CTGF PROTEIN, HUMAN;

EID: 70349235490     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.23102     Document Type: Article
Times cited : (70)

References (35)
  • 1
    • 0032787927 scopus 로고    scopus 로고
    • The connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed (CCN) family
    • Brigstock DR. The connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed (CCN) family. Endocr Rev 1999;20:189-206.
    • (1999) Endocr Rev , vol.20 , pp. 189-206
    • Brigstock, D.R.1
  • 2
    • 59649107705 scopus 로고    scopus 로고
    • Functions and mechanisms of action of CCN matricellular proteins
    • Chen CC, Lau LF. Functions and mechanisms of action of CCN matricellular proteins. Int J Biochem Cell Biol 2009;41:771-783.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 771-783
    • Chen, C.C.1    Lau, L.F.2
  • 3
    • 0042092032 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis
    • DOI 10.1016/S1386-6346(03)00115-3
    • Rachfal AW, Brigstock DR. Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis. Hepatol Res 2003;26:1-9. (Pubitemid 36939924)
    • (2003) Hepatology Research , vol.26 , Issue.1 , pp. 1-9
    • Rachfal, A.W.1    Brigstock, D.R.2
  • 4
    • 0342264463 scopus 로고    scopus 로고
    • Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells
    • DOI 10.1016/S0168-8278(00)80244-5
    • Williams EJ, Gaca MD, Brigstock DR, Arthur MJ, Benyon RC. Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells. J Hepatol 2000;32:754-761. (Pubitemid 30262735)
    • (2000) Journal of Hepatology , vol.32 , Issue.5 , pp. 754-761
    • Williams, E.J.1    Gaca, M.D.A.2    Brigstock, D.R.3    Arthur, M.J.P.4    Benyon, R.C.5
  • 5
    • 0035066961 scopus 로고    scopus 로고
    • Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis
    • Sedlaczek N, Jia JD, Bauer M, Herbst H, Ruehl M, Hahn EG, et al. Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis. Am J Pathol 2001;158:1239-1244. (Pubitemid 32281287)
    • (2001) American Journal of Pathology , vol.158 , Issue.4 , pp. 1239-1244
    • Sedlaczek, N.1    Jia, J.-D.2    Bauer, M.3    Herbst, H.4    Ruehl, M.5    Hahn, E.G.6    Schuppan, D.7
  • 6
    • 34248179500 scopus 로고    scopus 로고
    • SiRNA-mediated knockdown of connective tissue growth factor prevents N-nitrosodimethylamine-induced hepatic fibrosis in rats
    • DOI 10.1038/sj.gt.3302929, PII 3302929
    • George J, Tsutsumi M. siRNA-mediated knockdown of connective tissue growth factor prevents N-nitrosodimethylamine-induced hepatic fibrosis in rats. Gene Ther 2007;14:790-803. (Pubitemid 46706059)
    • (2007) Gene Therapy , vol.14 , Issue.10 , pp. 790-803
    • George, J.1    Tsutsumi, M.2
  • 8
    • 33748308746 scopus 로고    scopus 로고
    • Connective tissue growth factor in serum as a new candidate test for assessment of hepatic fibrosis
    • DOI 10.1373/clinchem.2006.070466
    • Gressner AM, Yagmur E, Lahme B, Gressner O, Stanzel S. Connective tissue growth factor in serum as a new candidate test for assessment of hepatic fibrosis. Clin Chem 2006;52:1815-1817. (Pubitemid 44330719)
    • (2006) Clinical Chemistry , vol.52 , Issue.9 , pp. 1815-1817
    • Gressner, A.M.1    Yagmur, E.2    Lahme, B.3    Gressner, O.4    Stanzel, S.5
  • 9
    • 48949084865 scopus 로고    scopus 로고
    • Connective tissue growth factor: A fibrogenic master switch in fibrotic liver diseases
    • Gressner OA, Gressner AM. Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases. Liver Int 2008;28:1065-1079.
    • (2008) Liver Int , vol.28 , pp. 1065-1079
    • Gressner, O.A.1    Gressner, A.M.2
  • 10
    • 0034703632 scopus 로고    scopus 로고
    • Kinetics of expression of connective tissue growth factor gene during liver regeneration after partial hepatectomy and D-galactosamine-induced liver injury in rats
    • DOI 10.1006/bbrc.2000.3693
    • Ujike K, Shinji T, Hirasaki S, Shiraha H, Nakamura M, Tsuji T, et al. Kinetics of expression of connective tissue growth factor gene during liver regeneration after partial hepatectomy and D-galactosamine- induced liver injury in rats. Biochem Biophys Res Commun 2000;277:448-454. (Pubitemid 30807488)
    • (2000) Biochemical and Biophysical Research Communications , vol.277 , Issue.2 , pp. 448-454
    • Ujike, K.1    Shinji, T.2    Hirasaki, S.3    Shiraha, H.4    Nakamura, M.5    Tsuji, T.6    Koide, N.7
  • 11
    • 0035081385 scopus 로고    scopus 로고
    • Expression of Nov, CYR61 and CTGF genes in human hepatocellular carcinoma
    • Hirasaki S, Koide N, Ujike K, Shinji T, Tsuji T. Expression of Nov, CYR61 and CTGF genes in human hepatocellular carcinoma. Hepatol Res 2001;19:294-305.
    • (2001) Hepatol Res , vol.19 , pp. 294-305
    • Hirasaki, S.1    Koide, N.2    Ujike, K.3    Shinji, T.4    Tsuji, T.5
  • 12
    • 0041343764 scopus 로고    scopus 로고
    • Expression of connective tissue growth factor (CTGF) in alcoholic liver fibrosis and in HEPG2 cell line stably expressiong cytochrome P-4502E1
    • Abstract
    • Konishi M, Kato S, Kajihara M, Yamagishi Y, Horie Y, Aiso S, et al. Expression of connective tissue growth factor (CTGF) in alcoholic liver fibrosis and in HEPG2 cell line stably expressiong cytochrome P-4502E1 [Abstract]. HEPATOLOGY 2002;36:248A.
    • (2002) Hepatology , vol.36
    • Konishi, M.1    Kato, S.2    Kajihara, M.3    Yamagishi, Y.4    Horie, Y.5    Aiso, S.6
  • 13
    • 21044433414 scopus 로고    scopus 로고
    • HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-beta1
    • Shin JY, Hur W, Wang JS, Jang JW, Kim CW, Bae SH, et al. HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-beta1. Exp Mol Med 2005;37:138-145.
    • (2005) Exp Mol Med , vol.37 , pp. 138-145
    • Shin, J.Y.1    Hur, W.2    Wang, J.S.3    Jang, J.W.4    Kim, C.W.5    Bae, S.H.6
  • 14
    • 53249092406 scopus 로고    scopus 로고
    • Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPAR-gamma and SMAD2/3-dependent pathways
    • Gressner OA, Lahme B, Rehbein K, Siluschek M, Weiskirchen R, Gressner AM. Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPAR-gamma and SMAD2/3-dependent pathways. J Hepatol 2008;49:758-767.
    • (2008) J Hepatol , vol.49 , pp. 758-767
    • Gressner, O.A.1    Lahme, B.2    Rehbein, K.3    Siluschek, M.4    Weiskirchen, R.5    Gressner, A.M.6
  • 15
    • 36348932917 scopus 로고    scopus 로고
    • Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes
    • Weng HL, Ciuclan L, Liu Y, Hamzavi J, Godoy P, Gaitantzi H, et al. Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes. HEPATOLOGY 2007;46:1257-1270.
    • (2007) Hepatology , vol.46 , pp. 1257-1270
    • Weng, H.L.1    Ciuclan, L.2    Liu, Y.3    Hamzavi, J.4    Godoy, P.5    Gaitantzi, H.6
  • 17
    • 0023339694 scopus 로고
    • An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice
    • Pinkert CA, Ornitz DM, Brinster RL, Palmiter RD. An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice. Genes Dev 1987;1:268-276.
    • (1987) Genes Dev , vol.1 , pp. 268-276
    • Pinkert, C.A.1    Ornitz, D.M.2    Brinster, R.L.3    Palmiter, R.D.4
  • 18
    • 0037291194 scopus 로고    scopus 로고
    • Establishment of a recombinant expression system for connective tissue growth factor (CTGF) that models CTGF processing in utero
    • Ball DK, Moussad EE, Rageh MA, Kemper SA, Brigstock DR. Establishment of a recombinant expression system for connective tissue growth factor (CTGF) that models CTGF processing in utero. Reproduction 2003;125:271-284.
    • (2003) Reproduction , vol.125 , pp. 271-284
    • Ball, D.K.1    Moussad, E.E.2    Rageh, M.A.3    Kemper, S.A.4    Brigstock, D.R.5
  • 19
    • 0019781507 scopus 로고
    • Mouse liver cell culture. I. Hepatocyte isolation
    • Klaunig JE, Goldblatt PJ, Hinton DE, Lipsky MM, Chacko J, Trump BF. Mouse liver cell culture. I. Hepatocyte isolation. In Vitro 1981;17:913-925. (Pubitemid 12181443)
    • (1981) In Vitro , vol.17 , Issue.10 , pp. 913-925
    • Klaunig, J.E.1    Goldblatt, P.J.2    Hinton, D.E.3
  • 20
    • 54949124162 scopus 로고    scopus 로고
    • Regulation of CCN2 mRNA expression and promoter activity in activated hepatic stellate cells
    • Leask A, Chen S, Pala D, Brigstock DR. Regulation of CCN2 mRNA expression and promoter activity in activated hepatic stellate cells. J Cell Commun Signal 2008;2:49-56.
    • (2008) J Cell Commun Signal , vol.2 , pp. 49-56
    • Leask, A.1    Chen, S.2    Pala, D.3    Brigstock, D.R.4
  • 21
    • 23144461629 scopus 로고    scopus 로고
    • Comparison of murine cirrhosis models induced by hepatotoxin administration and common bile duct ligation
    • Chang ML, Yeh CT, Chang PY, Chen JC. Comparison of murine cirrhosis models induced by hepatotoxin administration and common bile duct ligation. World J Gastroenterol 2005;11:4167-4172.
    • (2005) World J Gastroenterol , vol.11 , pp. 4167-4172
    • Chang, M.L.1    Yeh, C.T.2    Chang, P.Y.3    Chen, J.C.4
  • 22
    • 0033405368 scopus 로고    scopus 로고
    • Immunohistochemical localization of connective tissue growth factor (CTGF) in the mouse embryo between days 7.5 and 14.5 of gestation
    • Surveyor GA, Brigstock DR. Immunohistochemical localization of connective tissue growth factor (CTGF) in the mouse embryo between days 7.5 and 14.5 of gestation. Growth Factors 1999;17:115-124.
    • (1999) Growth Factors , vol.17 , pp. 115-124
    • Surveyor, G.A.1    Brigstock, D.R.2
  • 23
    • 0034803217 scopus 로고    scopus 로고
    • Steroidal regulation of connective tissue growth factor (CCN2; CTGF) synthesis in the mouse uterus
    • Rageh MA, Moussad EE, Wilson AK, Brigstock DR. Steroidal regulation of connective tissue growth factor (CCN2; CTGF) synthesis in the mouse uterus. Mol Pathol 2001;54:338-346.
    • (2001) Mol Pathol , vol.54 , pp. 338-346
    • Rageh, M.A.1    Moussad, E.E.2    Wilson, A.K.3    Brigstock, D.R.4
  • 24
    • 0034817108 scopus 로고    scopus 로고
    • Overexpression of connective tissue growth factor/hypertrophic chondrocyte-specific gene product 24 decreases bone density in adult mice and induces dwarfism
    • DOI 10.1006/bbrc.2001.4379
    • Nakanishi T, Yamaai T, Asano M, Nawachi K, Suzuki M, Sugimoto T, et al. Overexpression of connective tissue growth factor/hypertrophic chondrocyte-specific gene product 24 decreases bone density in adult mice and induces dwarfism. Biochem Biophys Res Commun 2001;281:678-681. (Pubitemid 32917854)
    • (2001) Biochemical and Biophysical Research Communications , vol.281 , Issue.3 , pp. 678-681
    • Nakanishi, T.1    Yamaai, T.2    Asano, M.3    Nawachi, K.4    Suzuki, M.5    Sugimoto, T.6    Takigawa, M.7
  • 26
    • 50449109286 scopus 로고    scopus 로고
    • Skeletal overexpression of connective tissue growth factor impairs bone formation and causes osteopenia
    • Smerdel-Ramoya A, Zanotti S, Stadmeyer L, Durant D, Canalis E. Skeletal overexpression of connective tissue growth factor impairs bone formation and causes osteopenia. Endocrinology 2008;149:4374-4381.
    • (2008) Endocrinology , vol.149 , pp. 4374-4381
    • Smerdel-Ramoya, A.1    Zanotti, S.2    Stadmeyer, L.3    Durant, D.4    Canalis, E.5
  • 27
    • 1542305557 scopus 로고    scopus 로고
    • 3 and Heparan Sulfate Proteoglycan
    • DOI 10.1074/jbc.M313204200
    • Gao R, Brigstock DR. Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin alphavbeta3 and heparan sulfate proteoglycan. J Biol Chem 2004;279:8848-8855. (Pubitemid 38295943)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.10 , pp. 8848-8855
    • Gao, R.1    Brigstock, D.R.2
  • 28
    • 33847133425 scopus 로고    scopus 로고
    • Connective tissue growth factor binds to fibronectin through the type I repeat modules and enhances the affinity of fibronectin to fibrin
    • Yoshida K, Munakata H. Connective tissue growth factor binds to fibronectin through the type I repeat modules and enhances the affinity of fibronectin to fibrin. Biochim Biophys Acta 2007;1770:672-680.
    • (2007) Biochim Biophys Acta , vol.1770 , pp. 672-680
    • Yoshida, K.1    Munakata, H.2
  • 30
    • 32344444422 scopus 로고    scopus 로고
    • CT domain of CCN2/CTGF directly interacts with fibronectin and enhances cell adhesion of chondrocytes through integrin alpha5beta1
    • Hoshijima M, Hattori T, Inoue M, Araki D, Hanagata H, Miyauchi A, et al. CT domain of CCN2/CTGF directly interacts with fibronectin and enhances cell adhesion of chondrocytes through integrin alpha5beta1. FEBS Lett 2006;580:1376-1382.
    • (2006) FEBS Lett , vol.580 , pp. 1376-1382
    • Hoshijima, M.1    Hattori, T.2    Inoue, M.3    Araki, D.4    Hanagata, H.5    Miyauchi, A.6
  • 31
    • 40949127801 scopus 로고    scopus 로고
    • Connective tissue growth factor with a novel fibronectin binding site promotes cell adhesion and migration during rat oval cell activation
    • Pi L, Ding X, Jorgensen M, Pan JJ, Oh SH, Pintilie D, et al. Connective tissue growth factor with a novel fibronectin binding site promotes cell adhesion and migration during rat oval cell activation. HEPATOLOGY 2008;47:996-1004.
    • (2008) Hepatology , vol.47 , pp. 996-1004
    • Pi, L.1    Ding, X.2    Jorgensen, M.3    Pan, J.J.4    Oh, S.H.5    Pintilie, D.6
  • 32
    • 0036051343 scopus 로고    scopus 로고
    • Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta
    • DOI 10.1038/ncb826
    • Abreu JG, Ketpura NI, Reversade B, De Robertis EM. Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta. Nat Cell Biol 2002;4:599-604. (Pubitemid 34905599)
    • (2002) Nature Cell Biology , vol.4 , Issue.8 , pp. 599-604
    • Abreu, J.G.1    Ketpura, N.I.2    Reversade, B.3    De Robertis, E.M.4
  • 33
    • 0032794692 scopus 로고    scopus 로고
    • Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model
    • DOI 10.1002/(SICI)1097-4652(199910)181:1<153::AID-JCP16>3.0.CO;2-K
    • Mori T, Kawara S, Shinozaki M, Hayashi N, Kakinuma T, Igarashi A, et al. Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: a mouse fibrosis model. J Cell Physiol 1999;181:153-159. (Pubitemid 29400382)
    • (1999) Journal of Cellular Physiology , vol.181 , Issue.1 , pp. 153-159
    • Mori, T.1    Kawara, S.2    Shinozaki, M.3    Hayashi, N.4    Kakinuma, T.5    Igarashi, A.6    Takigawa, M.7    Nakanishi, T.8    Takehara, K.9
  • 34
    • 7744234278 scopus 로고    scopus 로고
    • Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis-resistant" BALB/c mouse lungs
    • Bonniaud P, Martin G, Margetts PJ, Ask K, Robertson J, Gauldie J, et al. Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis-resistant" BALB/c mouse lungs. Am J Respir Cell Mol Biol 2004;31:510-516.
    • (2004) Am J Respir Cell Mol Biol , vol.31 , pp. 510-516
    • Bonniaud, P.1    Martin, G.2    Margetts, P.J.3    Ask, K.4    Robertson, J.5    Gauldie, J.6
  • 35
    • 0036892365 scopus 로고    scopus 로고
    • Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15
    • DOI 10.1053/gast.2002.37069
    • Hillebrandt S, Goos C, Matern S, Lammert F. Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15. Gastroenterology 2002;123:2041-2051. (Pubitemid 35408326)
    • (2002) Gastroenterology , vol.123 , Issue.6 , pp. 2041-2051
    • Hillebrandt, S.1    Goos, C.2    Matern, S.3    Lammert, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.