CCN family 2/connective tissue growth factor (CCN2/CTGF) regulates the expression of Vegf through Hif-1α expression in a chondrocytic cell line, HCS-2/8, under hypoxic condition

Bone

Volumn 44, Issue 1, 2009, Pages 24-31

  Nishida, Takashi ^a   Kondo, Seiji ^b   Maeda, Azusa ^a   Kubota, Satoshi ^a   Lyons, Karen M ^c   Takigawa, Masaharu ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CCN family 2 connective tissue growth factor (CCN2 CTGF); Chondrocyte differentiation; Hypoxia inducible factor (HIF) 1 ; Signal conductor; Vascular endothelial growth factor (VEGF)

Indexed keywords

COMPLEMENTARY DNA; CONNECTIVE TISSUE GROWTH FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LUCIFERASE; MESSENGER RNA; VASCULOTROPIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CELL CULTURE; CELL DIFFERENTIATION; ENZYME ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMUR; GENE EXPRESSION; HYPOXIA; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; CELL HYPOXIA; CELL LINE; CELL NUCLEUS; CHONDROCYTES; CONNECTIVE TISSUE GROWTH FACTOR; GENE EXPRESSION REGULATION; GROWTH PLATE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; PROMOTER REGIONS, GENETIC; PROTEIN TRANSPORT; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 57449108288     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2008.08.125     Document Type: Article

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