Network insights into the genes regulated by hepatocyte nuclear factor 4 in response to drug induced perturbations: A review

Current Drug Discovery Technologies

Volumn 10, Issue 2, 2013, Pages 147-154

  Azmi, Asfar S ^a   Bao, Ginny W ^a   Gao, Jiankun ^a   Mohammad, Ramzi M ^a   Sarkar, Fazlul H ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Hepatocyte nuclear factors; HNF1; HNF3; HNF4; HNF4 ; HNF4 targeted drug design; HNFs; Network pharmacology; P53; Pancreatic ductal adenocarcinoma; Systems biology

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYTOCHROME P450 3A4; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPATOCYTE NUCLEAR FACTOR 3; HEPATOCYTE NUCLEAR FACTOR 3GAMMA; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; HEPATOCYTE NUCLEAR FACTOR 6; I KAPPA B; OXALIPLATIN; PROTEIN INHIBITOR; PROTEIN MDM2; PROTEIN P53;

APOPTOSIS; BINDING SITE; CANCER CHEMOTHERAPY; CANCER RESEARCH; CANCER THERAPY; CELL DIFFERENTIATION; DNA BINDING MOTIF; DOWN REGULATION; DRUG DESIGN; DRUG DEVELOPMENT; DRUG METABOLISM; DRUG POTENCY; DRUG TARGETING; GENE REGULATORY NETWORK; HUMAN; IN VITRO STUDY; LIVER CELL CARCINOMA; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; HEPATOCYTE NUCLEAR FACTORS; HUMANS; NEOPLASMS; SYSTEMS BIOLOGY; TUMOR MARKERS, BIOLOGICAL;

EID: 84882446588     PISSN: 15701638     EISSN: 18756220     Source Type: Journal    
DOI: 10.2174/1570163811310020007     Document Type: Review

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