Structural basis for HNF-4α activation by ligand and coactivator binding

Journal of Biological Chemistry

Volumn 279, Issue 22, 2004, Pages 23311-23316

  Duda, Karen ^a   Chi, Young In ^a,b   Shoelson, Steven E ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c JOSLIN DIABETES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CRYSTAL STRUCTURE; ENZYMES; FATTY ACIDS; STABILIZATION;

LIGAND BINDING DOMAIN (LBD); NUCLEAR RECEPTOR;

BIOCHEMISTRY;

CELL NUCLEUS RECEPTOR; FATTY ACID; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; LIGAND; TRANSCRIPTION FACTOR;

ALPHA HELIX; ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVE SITE; LIGAND BINDING; PHASE TRANSITION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; STRUCTURE ANALYSIS;

BINDING SITES; DNA-BINDING PROTEINS; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; LIGANDS; MODELS, MOLECULAR; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS;

EID: 2542496085     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M400864200     Document Type: Article

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