Diacylglycerol kinase θ couples farnesoid X receptor-dependent bile acid signalling to Akt activation and glucose homoeostasis in hepatocytes

Biochemical Journal

Volumn 454, Issue 2, 2013, Pages 267-274

  Cai, Kai ^a   Sewer, Marion B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bile acid; Diacylglycerol kinase (DGK ); Farnesoid X receptor (FXR); Hepatocyte; Phosphatidic acid

Indexed keywords

3 [2 [2 CHLORO 4 [3 (2,6 DICHLOROPHENYL) 5 ISOPROPYL 4 ISOXAZOLYLMETHOXY]PHENYL]VINYL]BENZOIC ACID; BILE ACID; CHENODEOXYCHOLIC ACID; DIACYLGLYCEROL KINASE; LUCIFERASE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR;

ARTICLE; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE ACTIVITY; GLUCOSE HOMEOSTASIS; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPORTER GENE;

CELLS, CULTURED; CHENODEOXYCHOLIC ACID; DIACYLGLYCEROL KINASE; GENE EXPRESSION REGULATION; GENE SILENCING; GENES, REPORTER; GLUCOSE; HEP G2 CELLS; HEPATOCYTES; HUMANS; ISOENZYMES; ISOXAZOLES; MULTIPROTEIN COMPLEXES; MUTATION; PHOSPHATIDIC ACIDS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84881518400     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130609     Document Type: Article

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