Dual regulation of diacylglycerol kinase (DGK)-θ: Polybasic proteins promote activation by phospholipids and increase substrate affinity

Journal of Biological Chemistry

Volumn 287, Issue 50, 2012, Pages 41619-41627

  Tu Sekine, Becky ^a   Raben, Daniel M ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC PHOSPHOLIPIDS; COFACTORS; DIACYLGLYCEROL; DIACYLGLYCEROL KINASE; INTERFACIAL ACTIVITY; ISOFORMS; MEMBRANE ASSOCIATION; MEMBRANE SURFACE; POSITIVELY CHARGED PROTEINS; PROTEIN DOMAINS; PURIFIED ENZYME; SIGNALING CASCADES; SUBSTRATE AFFINITY;

ENZYMES; GLYCEROL; PHOSPHOLIPIDS; PURIFICATION;

PROTEINS;

DIACYLGLYCEROL KINASE; DIACYLGLYCEROL KINASE THETA; PHOSPHOLIPID; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DENSITOMETRY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME REGULATION; ENZYME SPECIFICITY; GENE TRANSLOCATION; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY;

ANIMALS; CATTLE; CELL MEMBRANE; COENZYMES; DIACYLGLYCEROL KINASE; ENZYME ACTIVATION; HEK293 CELLS; HISTONES; HUMANS; PHOSPHOLIPIDS; TAU PROTEINS;

EID: 84871289332     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.404855     Document Type: Article

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