Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via Gαi-protein-coupled receptors and the AKT pathway

Journal of Lipid Research

Volumn 51, Issue 8, 2010, Pages 2234-2244

  Cao, Risheng ^a   Cronk, Zhumei Xu ^a   Zha, Weibin ^a   Sun, Lixin ^a   Wang, Xuan ^a   Fang, Youwen ^a   Studer, Elaine ^a   Zhou, Huiping ^a   Pandak, William M ^a   Dent, Paul ^a   Gil, Gregorio ^a   Hylemon, Phillip B ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Chronic bile fistula rat; GW4064; Primary rat hepatocyte; Protein kinase C zeta; Serine threonine kinase AKT (protein kinase B)

Indexed keywords

BILE ACID; FARNESOID X RECEPTOR; G PROTEIN COUPLED RECEPTOR; GLUCOSE 6 PHOSPHATASE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE SHP; TRANSCRIPTION FACTOR FKHR; CARBOXYLYASE; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR; INSULIN; MESSENGER RNA; NUCLEAR RECEPTOR SUBFAMILY 0, GROUP B, MEMBER 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SERINE THREONINE KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE; TAUROCHOLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT FISTULA; CONTROLLED STUDY; DNA BINDING; DOWN REGULATION; GENE EXPRESSION REGULATION; GLUCONEOGENESIS; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CYTOLOGY; DRUG EFFECTS; FISTULA; GENETICS; LIVER; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CARBOXY-LYASES; DOWN-REGULATION; FISTULA; GLUCONEOGENESIS; GLUCOSE-6-PHOSPHATASE; HEPATOCYTES; INSULIN; LIVER; MALE; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; SIGNAL TRANSDUCTION; TAUROCHOLIC ACID; PHOSPHATIDYLINOSITOL 3-KINASES;

EID: 77956838050     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M004929     Document Type: Article

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