Novel ferrocenyl derivatives exert anti-cancer effect in human lung cancer cells in vitro via inducing G 1 -phase arrest and senescence

Acta Pharmacologica Sinica

Volumn 34, Issue 7, 2013, Pages 960-968

  Li, Ying ^a   Ma, Han Lin ^a   Han, Lei ^a   Liu, Wei Yong ^a   Zhao, Bao Xiang ^a   Zhang, Shang Li ^a   Miao, Jun Ying ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

apoptosis; cell cycle arrest; ferrocene; human lung cancer; p38; ROS; senescence; senescence Associated galactosidase; triazoles

Indexed keywords

ACETYLCYSTEINE; BETA GALACTOSIDASE; FERROCENE DERIVATIVE; LACTATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; SYNAPTOPHYSIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL AGING; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME RELEASE; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION;

ANTINEOPLASTIC AGENTS; CELL AGING; CELL LINE, TUMOR; CELL SURVIVAL; FERROUS COMPOUNDS; G1 PHASE CELL CYCLE CHECKPOINTS; HUMANS; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE OXYGEN SPECIES;

EID: 84881406696     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.19     Document Type: Article

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