1-Acylthiosemicarbazides, 1,2,4-triazole-5(4H)-thiones, 1,3,4-thiadiazoles and hydrazones containing 5-methyl-2-benzoxazolinones: Synthesis, analgesic-anti-inflammatory and antimicrobial activities

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 17, 2007, Pages 5738-5751

  Salgin Gökşen, Umut ^a   Gökhan Kelekçi, Nesrin ^a   Göktaş, Özgür ^b   Köysal, Yavuz ^c   Kiliç, Ekrem ^a   Işik, Şamil ^c   Aktay, Göknur ^b   Özalp, Meral ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

^b INONU UNIVERSITY   (Turkey)

^c ONDOKUZ MAYIS UNIVERSITY   (Turkey)

Author keywords

2 Benzoxazolinone; Analgesic anti inflammatory and antimicrobial activities; Hydrazone; Thiadiazole; Thiosemicarbazide; Triazol

Indexed keywords

1 [2 (5 METHYL 2 BENZOXAZOLINON 3 YL)ACETYL] 4 ALLYLTHIOSEMICARBAZIDE; 1 [2 (5 METHYL 2 BENZOXAZOLINON 3 YL)ACETYL] 4 ETHYLTHIOSEMICARBAZIDE; 1 [2 (5 METHYL 2 BENZOXAZOLINON 3 YL)ACETYL] 4 METHYLTHIOSEMICARBAZIDE; 1 [2 (5 METHYL 2 BENZOXAZOLINON 3 YL)ACETYL] 4 PHENYLTHIOSEMICARBAZIDE; 1,2,4 TRIAZOLE DERIVATIVE; 1,3,4 THIADIAZOLE DERIVATIVE; 2 (5 METHYL 2 BENZOXAZOLINON 3 YL)ACETYLHYDRAZINE; 2 [2 (5 METHYL 2 BENZOXAZOLINON 3 YL)ACETYL] 4 BROMOBENZYLIDENEHYDRAZINE; 2 [2 (5 METHYL 2 BENZOXAZOLINON 3 YL)ACETYL] 4 CHLOROBENZYLIDENEHYDRAZINE; 2 [2 (5 METHYL 2 BENZOXAZOLINON 3 YL)ACETYL] 4 METHOXYBENZYLIDENEHYDRAZINE; 2 [2 (5 METHYL 2 BENZOXAZOLINON 3 YL)ACETYL] 4 METHYLBENZYLIDENEHYDRAZINE; 2 [2 (5 METHYL 2 BENZOXAZOLINON 3 YL)ACETYL]BENZYLIDENEHYDRAZINE; 2 BENZOXAZOLONE DERIVATIVE; 2 ETHYLAMINO 5 [(5 METHYL 2 BENZOXAZOLINON 3 YL)METHYL] 1,3,4 THIADIAZOLE; 2 METHYLAMINO 5 [(5 METHYL 2 BENZOXAZOLINON 3 YL)METHYL] 1,3,4 THIADIAZOLE; 2 PHENYLAMINO 5 [(5 METHYL 2 BENZOXAZOLINON 3 YL)METHYL] 1,3,4 THIADIAZOLE; 3 [(5 METHYL 2 BENZOXAZOLINON 3 YL)METHYL] 4 ALLYL 1H 1,2,4 TRIAZOLE 5(4H) THIONE; 3 [(5 METHYL 2 BENZOXAZOLINON 3 YL)METHYL] 4 ETHYL 1H 1,2,4 TRIAZOLE 5(4H) THIONE; 3 [(5 METHYL 2 BENZOXAZOLINON 3 YL)METHYL] 4 METHYL 1H 1,2,4 TRIAZOLE 5(4H) THIONE; 3 [(5 METHYL 2 BENZOXAZOLINON 3 YL)METHYL] 4 PHENYL 1H 1,2,4 TRIAZOLE 5(4H) THIONE; 5 METHYL 2 BENZOXAZOLINONE DERIVATIVE; AMPICILLIN; BENZYLIDENEHYDRAZINE DERIVATIVE; FLUCONAZOLE; HYDRAZINE DERIVATIVE; HYDRAZONE DERIVATIVE; INDOMETACIN; THIOSEMICARBAZIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG SYNTHESIS; MOUSE; NONHUMAN; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

ANALGESICS; ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS; BENZOXAZOLES; CRYSTALLOGRAPHY, X-RAY; EDEMA; HINDLIMB; HYDRAZONES; METHYLATION; MICE; MICROBIAL VIABILITY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SEMICARBAZIDES; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES; TRIAZOLES;

FUNGI;

EID: 34447267965     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.06.006     Document Type: Article

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