A novel copper complex of salicylaldehyde pyrazole hydrazone induces apoptosis through up-regulating integrin β4 in H322 lung carcinoma cells

European Journal of Medicinal Chemistry

Volumn 45, Issue 4, 2010, Pages 1438-1446

  Fan, ChuanDong ^a   Su, Hua ^a   Zhao, Jing ^a   Zhao, BaoXiang ^a   Zhang, ShangLi ^a   Miao, JunYing ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Apoptosis; Copper complex; Hydrazone; Integrin 4; Lung cancer cells

Indexed keywords

ANTINEOPLASTIC AGENT; BETA4 INTEGRIN; COPPER COMPLEX; N' (2 HYDROXYBENZYLIDENE) 1 (4 TERT BUTYLBENZYL) 3 PHENYL 1H PYRAZOLE 5 CARBOHYDRAZIDE COPPER; SALICYLALDEHYDE PYRAZOLE HYDRAZONE COPPER DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL LEVEL; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IMMUNOFLUORESCENCE TEST; LUNG CARCINOMA; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; COPPER; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; HYDRAZONES; IN SITU NICK-END LABELING; INTEGRIN BETA4; LUNG NEOPLASMS; ORGANOMETALLIC COMPOUNDS; RNA INTERFERENCE; UP-REGULATION;

EID: 77349100137     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.12.048     Document Type: Article

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