-
1
-
-
0028014529
-
Cell membrane resealing by a vesicular mechanism similar to neurotransmitter release.
-
Steinhardt, R. A., Bi, G., Alderton, J. M., Cell membrane resealing by a vesicular mechanism similar to neurotransmitter release. Science 1994, 263, 390-393.
-
(1994)
Science
, vol.263
, pp. 390-393
-
-
Steinhardt, R.A.1
Bi, G.2
Alderton, J.M.3
-
2
-
-
84860850876
-
Cell-penetrating peptides split into two groups based on modulation of intracellular calcium concentration.
-
Lorents, A., Kodavali, P.K., Oskolkov, N., Langel, Ü. et al., Cell-penetrating peptides split into two groups based on modulation of intracellular calcium concentration. J. Biol. Chem. 2012, 287, 16880-16889.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 16880-16889
-
-
Lorents, A.1
Kodavali, P.K.2
Oskolkov, N.3
Langel, U.4
-
3
-
-
1642362625
-
Drug delivery systems: Entering the mainstream.
-
Allen, T.M., Cullis, P. R., Drug delivery systems: Entering the mainstream. Science 2004, 303, 1818-1822.
-
(2004)
Science
, vol.303
, pp. 1818-1822
-
-
Allen, T.M.1
Cullis, P.R.2
-
4
-
-
0002034191
-
Cell-penetrating peptides.
-
Lindgren, M., Hällbrink, M., Prochiantz, A., Langel, Ü., Cell-penetrating peptides. Trends Pharmacol. Sci. 2000, 21, 99-103.
-
(2000)
Trends Pharmacol. Sci.
, vol.21
, pp. 99-103
-
-
Lindgren, M.1
Hällbrink, M.2
Prochiantz, A.3
Langel, U.4
-
5
-
-
79651474350
-
Biological responses towards cationic peptides and drug carriers.
-
Verdurmen, W.P.R., Brock, R., Biological responses towards cationic peptides and drug carriers. Trends Pharmacol. Sci. 2010, 32, 116-124.
-
(2010)
Trends Pharmacol. Sci.
, vol.32
, pp. 116-124
-
-
Verdurmen, W.P.R.1
Brock, R.2
-
6
-
-
33748433244
-
Cell-penetrating peptides as vectors for peptide, protein and oligonucleotide delivery.
-
Mae, M., Langel, Ü., Cell-penetrating peptides as vectors for peptide, protein and oligonucleotide delivery. Curr. Opin. Pharmacol. 2006, 6, 509-514.
-
(2006)
Curr. Opin. Pharmacol.
, vol.6
, pp. 509-514
-
-
Mae, M.1
Langel, U.2
-
7
-
-
0028239908
-
The third helix of the Antennapedia homeodomain translocates through biological membranes.
-
Derossi, D., Joliot, A.H., Chassaing, G., Prochiantz, A., The third helix of the Antennapedia homeodomain translocates through biological membranes. J. Biol. Chem. 1994, 269, 10444-10450.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 10444-10450
-
-
Derossi, D.1
Joliot, A.H.2
Chassaing, G.3
Prochiantz, A.4
-
8
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus.
-
Vivès, E., Brodin, P., Lebleu, B., A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 1997, 272, 16010-16017.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16010-16017
-
-
Vivès, E.1
Brodin, P.2
Lebleu, B.3
-
9
-
-
0036159271
-
Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat.
-
Silhol, M., Tyagi, M., Giacca, M., Lebleu, B. et al., Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat. Eur. J. Biochem. 2002, 269, 494-501.
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 494-501
-
-
Silhol, M.1
Tyagi, M.2
Giacca, M.3
Lebleu, B.4
-
10
-
-
0035575843
-
Cargo delivery kinetics of cell-penetrating peptides.
-
Hällbrink, M., Florén, A., Elmquist, A., Pooga, M. et al., Cargo delivery kinetics of cell-penetrating peptides. Biochim. Biophys. Acta 2001, 1515, 101-109.
-
(2001)
Biochim. Biophys. Acta
, vol.1515
, pp. 101-109
-
-
Hällbrink, M.1
Florén, A.2
Elmquist, A.3
Pooga, M.4
-
11
-
-
0346460957
-
Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake.
-
Richard, J.P., Melikov, K., Vives, E., Ramos, C. et al., Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. J. Biol. Chem. 2003, 278, 585-590.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 585-590
-
-
Richard, J.P.1
Melikov, K.2
Vives, E.3
Ramos, C.4
-
12
-
-
3843092828
-
Chances and pitfalls of cell penetrating peptides for cellular drug delivery.
-
Tréhin, R., Merkle, H.P., Chances and pitfalls of cell penetrating peptides for cellular drug delivery. Eur. J. Pharm. Biopharm. 2004, 58, 209-223.
-
(2004)
Eur. J. Pharm. Biopharm.
, vol.58
, pp. 209-223
-
-
Tréhin, R.1
Merkle, H.P.2
-
13
-
-
84864631153
-
Cell-penetrating peptides: Classes, origin, and current landscape.
-
Milletti, F., Cell-penetrating peptides: Classes, origin, and current landscape. Drug Discov. Today 2012, 17, 850-860.
-
(2012)
Drug Discov. Today
, vol.17
, pp. 850-860
-
-
Milletti, F.1
-
14
-
-
41949109107
-
Mitoparan and target-selective chimeric analogues: Membrane translocation and intracellular redistribution induces mitochondrial apoptosis.
-
Jones, S., Martel, C., Belzacq-Casagrande, A.S., Brenner, C. et al., Mitoparan and target-selective chimeric analogues: Membrane translocation and intracellular redistribution induces mitochondrial apoptosis. Biochim. Biophys. Acta 2008, 1783, 849-863.
-
(2008)
Biochim. Biophys. Acta
, vol.1783
, pp. 849-863
-
-
Jones, S.1
Martel, C.2
Belzacq-Casagrande, A.S.3
Brenner, C.4
-
15
-
-
37549056931
-
Characterization of a novel cytotoxic cell-penetrating peptide derived from p14ARF protein.
-
Johansson, H.J., El-Andaloussi, S., Holm, T., Mäe, M. et al., Characterization of a novel cytotoxic cell-penetrating peptide derived from p14ARF protein. Mol. Ther. 2008, 16, 115-123.
-
(2008)
Mol. Ther.
, vol.16
, pp. 115-123
-
-
Johansson, H.J.1
El-Andaloussi, S.2
Holm, T.3
Mäe, M.4
-
16
-
-
84855951575
-
Enantiomer-specific bioactivities of peptidomimetic analogues of mastoparan and mitoparan: Characterization of inverso mastoparan as a highly efficient cell penetrating peptide.
-
Jones, S., Howl, J., Enantiomer-specific bioactivities of peptidomimetic analogues of mastoparan and mitoparan: Characterization of inverso mastoparan as a highly efficient cell penetrating peptide. Bioconjug. Chem. 2012, 23, 47-56.
-
(2012)
Bioconjug. Chem.
, vol.23
, pp. 47-56
-
-
Jones, S.1
Howl, J.2
-
17
-
-
77955456084
-
Characterization of bioactive cell penetrating peptides from human cytochrome c: Protein mimicry and the development of a novel apoptogenic agent.
-
Jones, S., Holm, T., Mäger, I., Langel, Ü. et al., Characterization of bioactive cell penetrating peptides from human cytochrome c: Protein mimicry and the development of a novel apoptogenic agent. Chem.Biol. 2010, 17, 735-744.
-
(2010)
Chem.Biol.
, vol.17
, pp. 735-744
-
-
Jones, S.1
Holm, T.2
Mäger, I.3
Langel, U.4
-
18
-
-
77951229473
-
Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts.
-
Delaroche, D., Cantrelle, F.X., Subra, F., Van Heijenoort, C. et al., Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts. J. Biol. Chem. 2010, 285, 7712-7721.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 7712-7721
-
-
Delaroche, D.1
Cantrelle, F.X.2
Subra, F.3
Van Heijenoort, C.4
-
19
-
-
57349155304
-
Proteomimetic cell penetrating peptides.
-
Howl, J., Jones, S., Proteomimetic cell penetrating peptides. Int. J. Pept. Res. Ther. 2008, 14, 359-366.
-
(2008)
Int. J. Pept. Res. Ther.
, vol.14
, pp. 359-366
-
-
Howl, J.1
Jones, S.2
-
20
-
-
84944484435
-
The mechanism of pancreatic secretion.
-
Bayliss, W.M., Starling, E.H., The mechanism of pancreatic secretion. J. Physiol. 1902, 28, 325-353.
-
(1902)
J. Physiol.
, vol.28
, pp. 325-353
-
-
Bayliss, W.M.1
Starling, E.H.2
-
21
-
-
84881315303
-
-
(Ed.), Bioactive Peptides. CRC Press, Boca Raton, FL
-
Howl, J., Jones, S. (Ed.), Bioactive Peptides. CRC Press, Boca Raton, FL, 2009.
-
(2009)
-
-
Howl, J.1
Jones, S.2
-
22
-
-
84864970396
-
Bioportide: An emergent concept of bioactive cell-penetrating peptides.
-
Howl, J., Matou-Nasri, S., West, D.C., Farquhar, M. et al., Bioportide: An emergent concept of bioactive cell-penetrating peptides. Cell. Mol. Life. Sci. 2012, 69, 2951-2966.
-
(2012)
Cell. Mol. Life. Sci.
, vol.69
, pp. 2951-2966
-
-
Howl, J.1
Matou-Nasri, S.2
West, D.C.3
Farquhar, M.4
-
23
-
-
77958153239
-
In vivo biodistribution and efficacy of peptide mediated delivery.
-
Järver, P., Mäger, I., Langel, Ü., In vivo biodistribution and efficacy of peptide mediated delivery. Trends Pharmacol. Sci. 2010, 31, 528-535.
-
(2010)
Trends Pharmacol. Sci.
, vol.31
, pp. 528-535
-
-
Järver, P.1
Mäger, I.2
Langel, U.3
-
24
-
-
40849120181
-
Gateways and tools for drug delivery: Endocytic pathways and the cellular dynamics of cell penetrating peptides.
-
Jones, A.T., Gateways and tools for drug delivery: Endocytic pathways and the cellular dynamics of cell penetrating peptides. Int. J. Pharm. 2008, 354, 34-38.
-
(2008)
Int. J. Pharm.
, vol.354
, pp. 34-38
-
-
Jones, A.T.1
-
25
-
-
0036717194
-
The druggable genome.
-
Hopkins, A.L., Groom, C.R., The druggable genome. Nat. Rev. Drug. Discov. 2002, 1, 727-730.
-
(2002)
Nat. Rev. Drug. Discov.
, vol.1
, pp. 727-730
-
-
Hopkins, A.L.1
Groom, C.R.2
-
26
-
-
0024405504
-
Bivalent ligands and the message-address concept in the design of selective opioid receptor antagonists.
-
198910
-
Portoghese, P., Bivalent ligands and the message-address concept in the design of selective opioid receptor antagonists. Trends Pharmacol. Sci. 1989, 198910, 230-235.
-
(1989)
Trends Pharmacol. Sci.
, pp. 230-235
-
-
Portoghese, P.1
-
27
-
-
28844504689
-
Prediction of cell-penetrating peptides.
-
Hällbrink, M., Kilk, K., Elmquist, A., Lundberg, P. et al., Prediction of cell-penetrating peptides. Int. J. Pept. Res. Ther. 2005, 11, 249-259.
-
(2005)
Int. J. Pept. Res. Ther.
, vol.11
, pp. 249-259
-
-
Hällbrink, M.1
Kilk, K.2
Elmquist, A.3
Lundberg, P.4
-
28
-
-
38949213664
-
Predicting cell-penetrating peptides.
-
Hansen, M., Kilk, K., Langel, Ü., Predicting cell-penetrating peptides. Adv. Drug. Deliv. Rev. 2008, 60, 572-579.
-
(2008)
Adv. Drug. Deliv. Rev.
, vol.60
, pp. 572-579
-
-
Hansen, M.1
Kilk, K.2
Langel, U.3
-
29
-
-
84857509304
-
Small-molecule stabilization of protein-protein interactions: An underestimated concept in drug discovery?
-
Thiel, P., Kaiser, M., Ottmann, C., Small-molecule stabilization of protein-protein interactions: An underestimated concept in drug discovery? Angew. Chem. Int. Ed. Engl. 2012, 51, 2012-2018.
-
(2012)
Angew. Chem. Int. Ed. Engl.
, vol.51
, pp. 2012-2018
-
-
Thiel, P.1
Kaiser, M.2
Ottmann, C.3
-
30
-
-
0035575637
-
Drug discovery of the future: The implications of the human genome project.
-
Reiss, T., Drug discovery of the future: The implications of the human genome project. Trends Biotechnol. 2001, 19, 496-499.
-
(2001)
Trends Biotechnol.
, vol.19
, pp. 496-499
-
-
Reiss, T.1
-
31
-
-
29144531173
-
The druggable genome: An update.
-
Russ, A.P., Lampel, S., The druggable genome: An update. Drug. Discov. Today 2005, 10, 1607-1610.
-
(2005)
Drug. Discov. Today
, vol.10
, pp. 1607-1610
-
-
Russ, A.P.1
Lampel, S.2
-
32
-
-
79961007572
-
Trends in the exploitation of novel drug targets.
-
Rask-Andersen, M., Almén, M.S., Schiöth, H.B., Trends in the exploitation of novel drug targets. Nat. Rev. Drug. Discov. 2011, 10, 579-590.
-
(2011)
Nat. Rev. Drug. Discov.
, vol.10
, pp. 579-590
-
-
Rask-Andersen, M.1
Almén, M.S.2
Schiöth, H.B.3
-
33
-
-
78649633829
-
Small-molecule delivery by nanoparticles for anticancer therapy.
-
Chen, ZG., Small-molecule delivery by nanoparticles for anticancer therapy. Trends. Mol. Med. 2010, 16, 594-602.
-
(2010)
Trends. Mol. Med.
, vol.16
, pp. 594-602
-
-
Chen, Z.G.1
-
34
-
-
37749004225
-
Protein therapeutics: A summary and pharmacological classification.
-
Leader, B., Baca, Q.J., Golan, D.E., Protein therapeutics: A summary and pharmacological classification. Nat. Rev. Drug. Discov. 2008, 7, 21-39.
-
(2008)
Nat. Rev. Drug. Discov.
, vol.7
, pp. 21-39
-
-
Leader, B.1
Baca, Q.J.2
Golan, D.E.3
-
35
-
-
27744564465
-
Protein surface recognition and proteomimetics: Mimics of protein surface structure and function.
-
Fletcher, S., Hamilton, A.D., Protein surface recognition and proteomimetics: Mimics of protein surface structure and function. Curr. Opin. Chem. Biol. 2005, 9, 632-638.
-
(2005)
Curr. Opin. Chem. Biol.
, vol.9
, pp. 632-638
-
-
Fletcher, S.1
Hamilton, A.D.2
-
36
-
-
0028038601
-
Peptidomimetics - tailored enzyme inhibitors.
-
Gante, J., Peptidomimetics - tailored enzyme inhibitors. Angew. Chem. Int. Ed. 1994, 17, 1699-1720.
-
(1994)
Angew. Chem. Int. Ed.
, vol.17
, pp. 1699-1720
-
-
Gante, J.1
-
37
-
-
54849425126
-
Discovering and improving novel peptide therapeutics.
-
McGregor, D.P., Discovering and improving novel peptide therapeutics. Curr. Opin. Pharmacol. 2008, 8, 616-619.
-
(2008)
Curr. Opin. Pharmacol.
, vol.8
, pp. 616-619
-
-
McGregor, D.P.1
-
38
-
-
84857054586
-
Efficacy and safety of leuprolide acetate 6-month depot for suppression of testosterone in patients with prostate cancer.
-
Spitz, A., Young, J. M., Larsen, L., Mattia-Goldberg, C. et al., Efficacy and safety of leuprolide acetate 6-month depot for suppression of testosterone in patients with prostate cancer. Prostate Cancer Prostatic Dis. 2012, 15, 93-99.
-
(2012)
Prostate Cancer Prostatic Dis.
, vol.15
, pp. 93-99
-
-
Spitz, A.1
Young, J.M.2
Larsen, L.3
Mattia-Goldberg, C.4
-
39
-
-
76749161315
-
Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: A 24-week, randomized, multicentre, open-label trial.
-
Strowitzki, T., Marr, J., Gerlinger, C., Faustmann, T. et al., Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: A 24-week, randomized, multicentre, open-label trial. Hum. Reprod. 2010, 25, 633-641.
-
(2010)
Hum. Reprod.
, vol.25
, pp. 633-641
-
-
Strowitzki, T.1
Marr, J.2
Gerlinger, C.3
Faustmann, T.4
-
40
-
-
68549110328
-
Twenty years of cell-penetrating peptides: From molecular mechanisms to therapeutics.
-
Heitz, F., Morris, M.C., Divita, G., Twenty years of cell-penetrating peptides: From molecular mechanisms to therapeutics. Br. J. Pharmacol. 2009, 157, 195-206.
-
(2009)
Br. J. Pharmacol.
, vol.157
, pp. 195-206
-
-
Heitz, F.1
Morris, M.C.2
Divita, G.3
-
41
-
-
9644289511
-
The use of cell-penetrating peptides for drug delivery.
-
Temsamani, J., Vidal, P., The use of cell-penetrating peptides for drug delivery. Drug. Discov. Today 2004, 9, 1012-1019.
-
(2004)
Drug. Discov. Today
, vol.9
, pp. 1012-1019
-
-
Temsamani, J.1
Vidal, P.2
-
42
-
-
0024262589
-
Cellular uptake of the Tat protein from human immunodeficiency virus.
-
Franke, A.D., Pabo, C.O., Cellular uptake of the Tat protein from human immunodeficiency virus. Cell 1988, 55, 1189-1193.
-
(1988)
Cell
, vol.55
, pp. 1189-1193
-
-
Franke, A.D.1
Pabo, C.O.2
-
43
-
-
0032911885
-
The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin β-dependent nuclear localization signals.
-
Truant, R., Cullen, B. R., The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin β-dependent nuclear localization signals. Mol. Cell. Biol. 1999, 19, 1210-1217.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1210-1217
-
-
Truant, R.1
Cullen, B.R.2
-
44
-
-
13844272403
-
Adaptive translocation: The role of hydrogen binding and membrane potential in the uptake of guanidinium-rich transporters into cells.
-
Rothbard, J.B., Jessop, T.C., Wender, P.A., Adaptive translocation: The role of hydrogen binding and membrane potential in the uptake of guanidinium-rich transporters into cells. Adv. Drug Del. Rev. 2005, 57, 495-504.
-
(2005)
Adv. Drug Del. Rev.
, vol.57
, pp. 495-504
-
-
Rothbard, J.B.1
Jessop, T.C.2
Wender, P.A.3
-
45
-
-
0031754150
-
Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo.
-
Pooga, M., Soomets, U., Hällbrink, M., Valkna, A. et al., Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nat. Biotechnol. 1998, 16, 857-861.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 857-861
-
-
Pooga, M.1
Soomets, U.2
Hällbrink, M.3
Valkna, A.4
-
46
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse.
-
Schwarze, S.R., Ho, A., Vocero-Akbani, A., Dowdy, S.F., In vivo protein transduction: Delivery of a biologically active protein into the mouse. Science 1999, 285, 1569-1572.
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
47
-
-
85046914841
-
Peptide delivery to the brain via adsorptive-mediated endocytosis: Advances with SynB vectors.
-
Drin, G., Rousselle, C., Scherrmann, J-M., Rees, A. R. et al., Peptide delivery to the brain via adsorptive-mediated endocytosis: Advances with SynB vectors. AAPS PharmSci. 2002, 4, 61-67.
-
(2002)
AAPS PharmSci.
, vol.4
, pp. 61-67
-
-
Drin, G.1
Rousselle, C.2
Scherrmann, J.-M.3
Rees, A.R.4
-
48
-
-
0034126420
-
New advances in the transport of doxorubicin through the blood-brain barrier by a peptide vector-mediated strategy.
-
Rousselle, C., Clair, P., Lefauconnier, J. M., Kaczorek, M. et al., New advances in the transport of doxorubicin through the blood-brain barrier by a peptide vector-mediated strategy. Mol. Pharmacol. 2000, 57, 679-686.
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 679-686
-
-
Rousselle, C.1
Clair, P.2
Lefauconnier, J.M.3
Kaczorek, M.4
-
49
-
-
0035196836
-
Enhanced delivery of doxorubicin into the brain via a peptide-vector-mediated strategy: Saturation kinetics and specificity.
-
Rousselle, C., Smirnova, M., Clair, P., Lefauconnier, J.M. et al., Enhanced delivery of doxorubicin into the brain via a peptide-vector-mediated strategy: Saturation kinetics and specificity. J. Pharmacol. Exp. Ther. 2001, 296, 124-131.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.296
, pp. 124-131
-
-
Rousselle, C.1
Smirnova, M.2
Clair, P.3
Lefauconnier, J.M.4
-
50
-
-
77958152651
-
Structural polymorphism of non-covalent peptide-based delivery systems: Highway to cellular uptake.
-
Deshayes, S., Konate, K., Aldrian, G., Crombez, L. et al., Structural polymorphism of non-covalent peptide-based delivery systems: Highway to cellular uptake. Biochim. Biophys. Acta 2010, 1798, 2304-2314.
-
(2010)
Biochim. Biophys. Acta
, vol.1798
, pp. 2304-2314
-
-
Deshayes, S.1
Konate, K.2
Aldrian, G.3
Crombez, L.4
-
51
-
-
79952197259
-
Classes and prediction of cell-penetrating peptides.
-
Lindgren, M., Langel, Ü., Classes and prediction of cell-penetrating peptides. Methods Mol. Biol. 2011, 683, 3-19.
-
(2011)
Methods Mol. Biol.
, vol.683
, pp. 3-19
-
-
Lindgren, M.1
Langel, U.2
-
52
-
-
33745694051
-
Mechanistic aspects of CPP-mediated intracellular drug delivery: relevance of CPP self-assembly.
-
Pujals, S., Fernández-Carneado, J., López-Iglesias, C., Kogan, M.J. et al., Mechanistic aspects of CPP-mediated intracellular drug delivery: relevance of CPP self-assembly. Biochim. Biophys. Acta 2006, 1758, 264-279.
-
(2006)
Biochim. Biophys. Acta
, vol.1758
, pp. 264-279
-
-
Pujals, S.1
Fernández-Carneado, J.2
López-Iglesias, C.3
Kogan, M.J.4
-
53
-
-
1842529513
-
A stepwise dissection of the intracellular fate of cationic cell-penetrating peptides.
-
Fischer, R., Köhler, K., Fotin-Mleczek, M., Brock, R., A stepwise dissection of the intracellular fate of cationic cell-penetrating peptides. J. Biol. Chem. 2004, 279, 12625-12635.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 12625-12635
-
-
Fischer, R.1
Köhler, K.2
Fotin-Mleczek, M.3
Brock, R.4
-
54
-
-
0037169486
-
Possible existence of common internalization mechanisms among arginine-rich peptides.
-
Suzuki, T., Futaki, S., Niwa, M., Tanaka, S. et al., Possible existence of common internalization mechanisms among arginine-rich peptides. J. Biol. Chem. 2002, 277, 2437-2443.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2437-2443
-
-
Suzuki, T.1
Futaki, S.2
Niwa, M.3
Tanaka, S.4
-
55
-
-
84881316281
-
Intracellular translocation and differential accumulation of cell penetrating peptides in bovine spermatozoa: Evaluation of efficient delivery vectors that do not compromise human sperm motility.
-
Jones, S., Lukanowska, M., Suhorutsenko, J., Oxenham, S. et al., Intracellular translocation and differential accumulation of cell penetrating peptides in bovine spermatozoa: Evaluation of efficient delivery vectors that do not compromise human sperm motility. Hum. Reprod. 2013, 28, 1874-1889.
-
(2013)
Hum. Reprod.
, vol.28
, pp. 1874-1889
-
-
Jones, S.1
Lukanowska, M.2
Suhorutsenko, J.3
Oxenham, S.4
-
56
-
-
0035793619
-
Internalization of HIV-1 Tat requires cell surface heparan sulfate proteoglycans.
-
Tyagi, M., Rusnati, M., Presta, M., Giacca, M., Internalization of HIV-1 Tat requires cell surface heparan sulfate proteoglycans. J. Biol. Chem. 2001, 276, 3254-3261.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3254-3261
-
-
Tyagi, M.1
Rusnati, M.2
Presta, M.3
Giacca, M.4
-
57
-
-
24344448619
-
Cationic cell-penetrating peptides interfere with TNF signalling by induction of TNF receptor internalization.
-
Fotin-Mleczek, M., Welte, S., Mader, O., Duchardt, F. et al., Cationic cell-penetrating peptides interfere with TNF signalling by induction of TNF receptor internalization. J. Cell. Sci. 2005, 118, 3339-3351.
-
(2005)
J. Cell. Sci.
, vol.118
, pp. 3339-3351
-
-
Fotin-Mleczek, M.1
Welte, S.2
Mader, O.3
Duchardt, F.4
-
58
-
-
71749110589
-
Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling.
-
Kilk, K., Mahlapuu, R., Soomets, U., Langel, Ü., Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling. Toxicology 2009, 265, 87-95.
-
(2009)
Toxicology
, vol.265
, pp. 87-95
-
-
Kilk, K.1
Mahlapuu, R.2
Soomets, U.3
Langel, U.4
-
59
-
-
16344389701
-
Cation-pi interactions in protein-protein interfaces.
-
Crowley, P.B., Golovin, A., Cation-pi interactions in protein-protein interfaces. Proteins 2005, 59, 231-239.
-
(2005)
Proteins
, vol.59
, pp. 231-239
-
-
Crowley, P.B.1
Golovin, A.2
-
60
-
-
0028125659
-
Interaction of the bHLH-zip domain of c-Myc with H1-type peptides. Characterization of helicity in the H1 peptides by NMR.
-
Draeger, L.J., Mullen, G.P., Interaction of the bHLH-zip domain of c-Myc with H1-type peptides. Characterization of helicity in the H1 peptides by NMR. J. Biol. Chem. 1994, 269, 1785-1793.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1785-1793
-
-
Draeger, L.J.1
Mullen, G.P.2
-
61
-
-
17944392627
-
Inhibition of cancer cell growth and c-Myc transcriptional activity by a c-Myc helix 1-type peptide fused to an internalization sequence.
-
Giorello, L., Clerico, L., Pescarolo, M.P., Vikhanskaya, F. et al., Inhibition of cancer cell growth and c-Myc transcriptional activity by a c-Myc helix 1-type peptide fused to an internalization sequence. Cancer Res. 1998, 58, 3654-3659.
-
(1998)
Cancer Res.
, vol.58
, pp. 3654-3659
-
-
Giorello, L.1
Clerico, L.2
Pescarolo, M.P.3
Vikhanskaya, F.4
-
62
-
-
0035227317
-
A retro-inverso peptide homologous to helix 1 of c-Myc is a potent and specific inhibitor of proliferation in different cellular systems.
-
Pescarolo, M.P., Bagnasco, L., Malacarne, D., Valente, A. et al., A retro-inverso peptide homologous to helix 1 of c-Myc is a potent and specific inhibitor of proliferation in different cellular systems. FASEB J. 2001, 15, 31-33.
-
(2001)
FASEB J.
, vol.15
, pp. 31-33
-
-
Pescarolo, M.P.1
Bagnasco, L.2
Malacarne, D.3
Valente, A.4
-
63
-
-
20144387586
-
Sequence specific peptidomimetic molecules inhibitors of a protein-protein interaction at the helix 1 level of c-Myc.
-
Nieddu, E., Melchiori, A., Pescarolo, M.P., Bagnasco, L. et al., Sequence specific peptidomimetic molecules inhibitors of a protein-protein interaction at the helix 1 level of c-Myc. FASEB J. 2005, 19, 632-634.
-
(2005)
FASEB J.
, vol.19
, pp. 632-634
-
-
Nieddu, E.1
Melchiori, A.2
Pescarolo, M.P.3
Bagnasco, L.4
-
64
-
-
84874225181
-
Effects of Raf dimerization and its inhibition on normal and disease-associated Raf signaling.
-
Freeman, A.K., Ritt, D.A., Morrison, D.K., Effects of Raf dimerization and its inhibition on normal and disease-associated Raf signaling. Mol. Cell 2013, 49, 751-758.
-
(2013)
Mol. Cell
, vol.49
, pp. 751-758
-
-
Freeman, A.K.1
Ritt, D.A.2
Morrison, D.K.3
-
65
-
-
0034603897
-
An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo.
-
Midgley, C.A., Desterro, J.M., Saville, M.K., Howard, S. et al., An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo. Oncogene 2000, 19, 2312-2323.
-
(2000)
Oncogene
, vol.19
, pp. 2312-2323
-
-
Midgley, C.A.1
Desterro, J.M.2
Saville, M.K.3
Howard, S.4
-
66
-
-
33646587029
-
Intranasal delivery of the cytoplasmic domain of CTLA-4 using a novel protein transduction domain prevents allergic inflammation.
-
Choi, J.M., Ahn, M.H., Chae, W.J., Jung, Y.G. et al., Intranasal delivery of the cytoplasmic domain of CTLA-4 using a novel protein transduction domain prevents allergic inflammation. Nat. Med. 2006, 12, 574-579.
-
(2006)
Nat. Med.
, vol.12
, pp. 574-579
-
-
Choi, J.M.1
Ahn, M.H.2
Chae, W.J.3
Jung, Y.G.4
-
67
-
-
58149380717
-
Transduction of the cytoplasmic domain of CTLA-4 inhibits TcR-specific activation signals and prevents collagen-induced arthritis.
-
Choi, J.M., Ahn, M.H., Chae, W.J., Jung, Y.G. et al., Transduction of the cytoplasmic domain of CTLA-4 inhibits TcR-specific activation signals and prevents collagen-induced arthritis. Proc. Natl. Acad. Sci. U S A. 2008, 105, 19875-19880.
-
(2008)
Proc. Natl. Acad. Sci. U S A.
, vol.105
, pp. 19875-19880
-
-
Choi, J.M.1
Ahn, M.H.2
Chae, W.J.3
Jung, Y.G.4
-
68
-
-
34848848833
-
Inhibition of experimental allergic airways disease by local application of a cell-penetrating dominant-negative STAT-6 peptide.
-
McCusker, C.T., Wang, Y., Shan, J., Kinyanjui, M.W. et al., Inhibition of experimental allergic airways disease by local application of a cell-penetrating dominant-negative STAT-6 peptide. J. Immunol. 2007, 179, 2556-25564.
-
(2007)
J. Immunol.
, vol.179
, pp. 2556-25564
-
-
McCusker, C.T.1
Wang, Y.2
Shan, J.3
Kinyanjui, M.W.4
-
69
-
-
3843076296
-
Bax-inhibiting peptide derived from mouse and rat Ku70.
-
Yoshida, T., Tomioka, I., Nagahara, T., Holyst, T. et al., Bax-inhibiting peptide derived from mouse and rat Ku70. Biochem. Biophys. Res. Commun. 2004, 321, 961-966.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.321
, pp. 961-966
-
-
Yoshida, T.1
Tomioka, I.2
Nagahara, T.3
Holyst, T.4
-
70
-
-
58249139651
-
Bax-inhibiting peptide protects glutamate-induced cerebellar granule death by blocking Bax translocation.
-
Iriyama, T., Kamei, Y., Kozuma, S., Takertani, Y., Bax-inhibiting peptide protects glutamate-induced cerebellar granule death by blocking Bax translocation. Neurosci. Lett. 2009, 451, 11-15.
-
(2009)
Neurosci. Lett.
, vol.451
, pp. 11-15
-
-
Iriyama, T.1
Kamei, Y.2
Kozuma, S.3
Takertani, Y.4
-
71
-
-
36249024811
-
Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation.
-
Li, Y., Yokota, T., Gama, V., Yoshida, T. et al., Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation. Cell Death Differ. 2007, 14, 2058-2067.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 2058-2067
-
-
Li, Y.1
Yokota, T.2
Gama, V.3
Yoshida, T.4
-
72
-
-
8644286794
-
The role of Bax-inhibiting peptide in retinal ganglion cell apoptosis after optic nerve transection.
-
Qin, Q., Patil, K., Sharma, S. C., The role of Bax-inhibiting peptide in retinal ganglion cell apoptosis after optic nerve transection. Neurosci. Lett. 2004, 372, 17-21.
-
(2004)
Neurosci. Lett.
, vol.372
, pp. 17-21
-
-
Qin, Q.1
Patil, K.2
Sharma, S.C.3
-
73
-
-
77956410991
-
Neuroprotective effect of Bax-inhibiting peptide on neonatal brain injury.
-
Wang, X., Han, W., Du, X., Zu, C. et al., Neuroprotective effect of Bax-inhibiting peptide on neonatal brain injury. Stroke 2010, 41, 2050-2055.
-
(2010)
Stroke
, vol.41
, pp. 2050-2055
-
-
Wang, X.1
Han, W.2
Du, X.3
Zu, C.4
-
74
-
-
78651242264
-
Post-treatment of Bax-inhibiting peptide reduces neuronal death and behavioral deficits following global cerebral ischemia.
-
Han, B., Wang, Q., Cui, G., Shen, X. et al., Post-treatment of Bax-inhibiting peptide reduces neuronal death and behavioral deficits following global cerebral ischemia. Neurochem. Int. 2011, 58, 224-233.
-
(2011)
Neurochem. Int.
, vol.58
, pp. 224-233
-
-
Han, B.1
Wang, Q.2
Cui, G.3
Shen, X.4
-
75
-
-
34147099428
-
A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivo.
-
Milano, G., Morel, S., Bonny, C., Samaja, M. et al., A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivo. Am. J. Physiol. Heart Circ. Physiol. 2007, 292, H1828-H1835.
-
(2007)
Am. J. Physiol. Heart Circ. Physiol.
, vol.292
-
-
Milano, G.1
Morel, S.2
Bonny, C.3
Samaja, M.4
-
76
-
-
0035152487
-
Cell-permeable peptide inhibitors of JNK: Novel blockers of beta-cell death.
-
Bonny, C., Oberson, A., Negri, S., Sauser, C. et al., Cell-permeable peptide inhibitors of JNK: Novel blockers of beta-cell death. Diabetes 2001, 50, 77-82.
-
(2001)
Diabetes
, vol.50
, pp. 77-82
-
-
Bonny, C.1
Oberson, A.2
Negri, S.3
Sauser, C.4
-
77
-
-
36649004091
-
Time-course of c-Jun N-terminal kinase activation after cerebral ischemia and effect of D-JNKI1 on c-Jun and caspase-3 activation.
-
Repici, M., Centeno, C., Tomasi, S., Forloni, G. et al., Time-course of c-Jun N-terminal kinase activation after cerebral ischemia and effect of D-JNKI1 on c-Jun and caspase-3 activation. Neuroscience 2007, 150, 40-49.
-
(2007)
Neuroscience
, vol.150
, pp. 40-49
-
-
Repici, M.1
Centeno, C.2
Tomasi, S.3
Forloni, G.4
-
78
-
-
84858133686
-
The JNK inhibitor XG-102 protects against TNBS-induced colitis.
-
Reineke, K., Eminel, S., Dierck, F., Roessner, W. et al., The JNK inhibitor XG-102 protects against TNBS-induced colitis. PLoS One 2012, 7, e30985.
-
(2012)
PLoS One
, vol.7
-
-
Reineke, K.1
Eminel, S.2
Dierck, F.3
Roessner, W.4
-
79
-
-
77957369131
-
A peptide inhibitor of c-Jun N-terminal kinase for the treatment of endotoxin-induced uvetis.
-
Touchard, E., Omri, S., Naud, M.C., Berdugo, M. et al., A peptide inhibitor of c-Jun N-terminal kinase for the treatment of endotoxin-induced uvetis. Invest. Opthamol. Vis. Sci. 2010, 9, 4683-4693.
-
(2010)
Invest. Opthamol. Vis. Sci.
, vol.9
, pp. 4683-4693
-
-
Touchard, E.1
Omri, S.2
Naud, M.C.3
Berdugo, M.4
-
80
-
-
34548361839
-
Intratympanic treatment of acute acoustic trauma with a cell-permeable JNK ligand: A prospective randomized phaseI/II study.
-
Suckfuell, M., Canis, M., Strieth, S., Scherer, H. et al., Intratympanic treatment of acute acoustic trauma with a cell-permeable JNK ligand: A prospective randomized phaseI/II study. Acta Otolaryngol. 2007, 27, 938-942.
-
(2007)
Acta Otolaryngol.
, vol.27
, pp. 938-942
-
-
Suckfuell, M.1
Canis, M.2
Strieth, S.3
Scherer, H.4
-
81
-
-
0037372379
-
Protein kinase C modulates pulmonary endothelial permeability: A paradigm for acute lung injury.
-
Siflinger-Birnboim, A., Johnson, A., Protein kinase C modulates pulmonary endothelial permeability: A paradigm for acute lung injury. Am. J. Physiol. Lung Cell. Mol. Physiol. 2003, 284, L435-L451.
-
(2003)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.284
-
-
Siflinger-Birnboim, A.1
Johnson, A.2
-
82
-
-
0242442127
-
Inhibition of delta-protein kinase C protects against reperfusion injury of the ischemic heart in vivo.
-
Inagaki, K., Chen, L., Ikeno, F., Lee, F.H. et al., Inhibition of delta-protein kinase C protects against reperfusion injury of the ischemic heart in vivo. Circulation 2003, 2304-2307.
-
(2003)
Circulation
, pp. 2304-2307
-
-
Inagaki, K.1
Chen, L.2
Ikeno, F.3
Lee, F.H.4
-
83
-
-
74949112419
-
Regulation of TNF-induced oxygen radical production in human neutrophils: Role of delta-PKC.
-
Kilpatrick, L.E., Sun, S., Li, H., Vary, T.C. et al., Regulation of TNF-induced oxygen radical production in human neutrophils: Role of delta-PKC. J. Leukoc. Biol. 2010, 87, 153-164.
-
(2010)
J. Leukoc. Biol.
, vol.87
, pp. 153-164
-
-
Kilpatrick, L.E.1
Sun, S.2
Li, H.3
Vary, T.C.4
-
84
-
-
39449092458
-
Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction.
-
Bates, E., Bode, C., Costa, M., Gibson, C.M. et al., Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction. Circulation 2008, 117, 886-896.
-
(2008)
Circulation
, vol.117
, pp. 886-896
-
-
Bates, E.1
Bode, C.2
Costa, M.3
Gibson, C.M.4
-
85
-
-
0034629524
-
Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca(2+) release channel/ryanodine receptors.
-
Fajloun, Z., Kharrat, R., Chen, L., Lecomte, C. et al., Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca(2+) release channel/ryanodine receptors. FEBS Lett. 2000, 469, 179-185.
-
(2000)
FEBS Lett.
, vol.469
, pp. 179-185
-
-
Fajloun, Z.1
Kharrat, R.2
Chen, L.3
Lecomte, C.4
-
86
-
-
20144388051
-
Transduction of the scorpion toxin maurocalcine into cells. Evidence that the toxin crosses the plasma membrane.
-
Estève, E., Mabrouk, K., Dupuis, A., Smida-Rezgui, S. et al., Transduction of the scorpion toxin maurocalcine into cells. Evidence that the toxin crosses the plasma membrane. J. Biol. Chem. 2005, 280, 12833-12839.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 12833-12839
-
-
Estève, E.1
Mabrouk, K.2
Dupuis, A.3
Smida-Rezgui, S.4
-
87
-
-
77958549218
-
D-maurocalcine, a pharmacologically inert efficient cell-penetrating peptide analogue.
-
Poillot, C., Dridi, K., Bichraoui, H., Pêcher, J. et al., D-maurocalcine, a pharmacologically inert efficient cell-penetrating peptide analogue. J. Biol. Chem. 2010, 285, 34168-34180.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 34168-34180
-
-
Poillot, C.1
Dridi, K.2
Bichraoui, H.3
Pêcher, J.4
-
88
-
-
46749104437
-
Antiprion properties of prion protein-derived cell-penetrating peptides.
-
Löfgren, K., Wahlström, A., Lundberg, P., Langel, Ü. et al., Antiprion properties of prion protein-derived cell-penetrating peptides. FASEB J. 2008, 22, 2177-2184.
-
(2008)
FASEB J.
, vol.22
, pp. 2177-2184
-
-
Löfgren, K.1
Wahlström, A.2
Lundberg, P.3
Langel, U.4
-
89
-
-
0023918551
-
Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins).
-
Higashijima, T., Uzu, S., Nakajima, T., Ross, E.M., Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins). Biol. Chem. 1988, 263, 6491-6494.
-
(1988)
Biol. Chem.
, vol.263
, pp. 6491-6494
-
-
Higashijima, T.1
Uzu, S.2
Nakajima, T.3
Ross, E.M.4
-
90
-
-
72049131601
-
The chromogranin A-derived peptides vasostatin-1 and catestatin as regulatory peptides for cardiovascular functions.
-
Helle, K.B., The chromogranin A-derived peptides vasostatin-1 and catestatin as regulatory peptides for cardiovascular functions. Cardiovasc. Res. 2010, 85, 9-16.
-
(2010)
Cardiovasc. Res.
, vol.85
, pp. 9-16
-
-
Helle, K.B.1
-
91
-
-
0028094906
-
Vasoinhibitory activity of synthetic peptides from the amino terminus of chromogranin A.
-
Angeletti, R.H., Aardal, S., Serck-Hanssen, G., Gee, P. et al., Vasoinhibitory activity of synthetic peptides from the amino terminus of chromogranin A. Acta Physiol. Scand. 1994, 152, 11-19.
-
(1994)
Acta Physiol. Scand.
, vol.152
, pp. 11-19
-
-
Angeletti, R.H.1
Aardal, S.2
Serck-Hanssen, G.3
Gee, P.4
-
92
-
-
33947255616
-
Internalization and trafficking of cell surface proteoglycans and proteoglycan-binding ligands.
-
Payne, C.K., Jones, S.A., Chen, C., Zhuang, X., Internalization and trafficking of cell surface proteoglycans and proteoglycan-binding ligands. Traffic 2007, 8, 389-401.
-
(2007)
Traffic
, vol.8
, pp. 389-401
-
-
Payne, C.K.1
Jones, S.A.2
Chen, C.3
Zhuang, X.4
-
93
-
-
84859429245
-
Thiolated chitosan nanoparticles for the nasal administration of leuprolide: Bioavailability and pharmacokinetic characterization.
-
Shahnaz, G., Vetter, A., Barthelmes, J., Rahmat, D. et al., Thiolated chitosan nanoparticles for the nasal administration of leuprolide: Bioavailability and pharmacokinetic characterization. Int. J. Pharm. 2012, 428, 164-170.
-
(2012)
Int. J. Pharm.
, vol.428
, pp. 164-170
-
-
Shahnaz, G.1
Vetter, A.2
Barthelmes, J.3
Rahmat, D.4
-
94
-
-
80054030236
-
Effective treatment of experimental ragweed-induced asthma with STAT-6-IP, a topically delivered cell-penetrating peptide.
-
Wang, Y., Li, Y., Shan, J., Fixman, E. et al., Effective treatment of experimental ragweed-induced asthma with STAT-6-IP, a topically delivered cell-penetrating peptide. Clin. Exp. Allergy 2011, 4, 1622-1630.
-
(2011)
Clin. Exp. Allergy
, vol.4
, pp. 1622-1630
-
-
Wang, Y.1
Li, Y.2
Shan, J.3
Fixman, E.4
-
95
-
-
84874584382
-
Noninvasive insulin delivery: The great potential of cell-penetrating peptides.
-
Kamei, N., Nielsen, E.J., Khafagy, El-S., Takeda-Morishita, M., Noninvasive insulin delivery: The great potential of cell-penetrating peptides. Ther. Deliv. 2013, 4, 315-326.
-
(2013)
Ther. Deliv.
, vol.4
, pp. 315-326
-
-
Kamei, N.1
Nielsen, E.J.2
Khafagy, E.-S.3
Takeda-Morishita, M.4
-
96
-
-
57349182296
-
Effect of cell-penetrating peptides on the nasal absorption of insulin.
-
Khafagy, El-S., Morishita, M., Isowa, K., Imai, J. et al., Effect of cell-penetrating peptides on the nasal absorption of insulin. J. Control. Release 2009, 133, 103-108.
-
(2009)
J. Control. Release
, vol.133
, pp. 103-108
-
-
Khafagy, E.-S.1
Morishita, M.2
Isowa, K.3
Imai, J.4
-
97
-
-
70349198899
-
Efficiency of cell-penetrating peptides on the nasal and intestinal absorption of therapeutic peptides and proteins.
-
Khafagy, El-S., Morishita, M., Kamei, N., Eda, Y. et al., Efficiency of cell-penetrating peptides on the nasal and intestinal absorption of therapeutic peptides and proteins. Int. J. Pharm. 2009, 381, 49-55.
-
(2009)
Int. J. Pharm.
, vol.381
, pp. 49-55
-
-
Khafagy, E.-S.1
Morishita, M.2
Kamei, N.3
Eda, Y.4
-
98
-
-
76549110719
-
The role of intermolecular interactions with penetratin and its analogue on the enhancement of absorption of nasal therapeutic peptides.
-
Khafagy, El-S., Morishita, M., Takayama, K., The role of intermolecular interactions with penetratin and its analogue on the enhancement of absorption of nasal therapeutic peptides. Int. J. Pharm. 2010, 388, 209-212.
-
(2010)
Int. J. Pharm.
, vol.388
, pp. 209-212
-
-
Khafagy, E.-S.1
Morishita, M.2
Takayama, K.3
-
99
-
-
80054735802
-
Cell-penetrating peptide-modified block copolymer micelles promote direct brain delivery via intranasal administration.
-
Kanazawa, T., Taki, H., Tanaka, K., Takashima, Y. et al., Cell-penetrating peptide-modified block copolymer micelles promote direct brain delivery via intranasal administration. Pharm. Res. 2011, 28, 2130-2139.
-
(2011)
Pharm. Res.
, vol.28
, pp. 2130-2139
-
-
Kanazawa, T.1
Taki, H.2
Tanaka, K.3
Takashima, Y.4
-
100
-
-
79960250118
-
PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation.
-
Ezzat, K., Andaloussi, S.E., Zaghloul, E.M., Lehto, T. et al., PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation. Nucleic Acids Res. 2011, 39, 5284-5298.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 5284-5298
-
-
Ezzat, K.1
Andaloussi, S.E.2
Zaghloul, E.M.3
Lehto, T.4
-
101
-
-
79956015439
-
Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo.
-
Andaloussi, S.E., Lehto, T., Mäger, I., Rosenthal-Aizman, K. et al., Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo. Nucleic Acids Res. 2011, 39, 3972-3987.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 3972-3987
-
-
Andaloussi, S.E.1
Lehto, T.2
Mäger, I.3
Rosenthal-Aizman, K.4
-
102
-
-
0028114289
-
Antigenic mimicry of natural L-peptides with retro-inverso-peptidomimetics.
-
Guichard, G., Benkirane, N., Zeder-Lutz, G., van Regenmortel, M.H. et al., Antigenic mimicry of natural L-peptides with retro-inverso-peptidomimetics. Proc. Natl. Acad. Sci. USA 1994, 91, 9765-9769.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9765-9769
-
-
Guichard, G.1
Benkirane, N.2
Zeder-Lutz, G.3
van Regenmortel, M.H.4
-
104
-
-
33745107170
-
Strategies to improve plasma half life time of peptide and protein drugs.
-
Werle, M., Bernkop-Schnürch, A., Strategies to improve plasma half life time of peptide and protein drugs. Amino Acids 2006, 30, 351-367.
-
(2006)
Amino Acids
, vol.30
, pp. 351-367
-
-
Werle, M.1
Bernkop-Schnürch, A.2
-
105
-
-
39149103400
-
The design of guanidinium-rich transporters and their internalization mechanisms.
-
Wender, P.A., Galliher, W.C., Goun, E.A., Jones, L.R. et al., The design of guanidinium-rich transporters and their internalization mechanisms. Adv. Drug. Deliv. Rev. 2008, 60, 452-472.
-
(2008)
Adv. Drug. Deliv. Rev.
, vol.60
, pp. 452-472
-
-
Wender, P.A.1
Galliher, W.C.2
Goun, E.A.3
Jones, L.R.4
-
106
-
-
0026726041
-
Peptoids: a modular approach to drug discovery.
-
Simon, R.J., Kania, R.S., Zuckermann, R.N., Huebner, V.D. et al., Peptoids: a modular approach to drug discovery. Proc. Natl. Acad. Sci. USA 1992, 89, 9367-9371.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9367-9371
-
-
Simon, R.J.1
Kania, R.S.2
Zuckermann, R.N.3
Huebner, V.D.4
-
107
-
-
25444448796
-
Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the alpha-conotoxin MII.
-
Clark, R.J., Fischer, H., Dempster, L., Daly, N.L. et al., Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the alpha-conotoxin MII. Proc. Natl. Acad. Sci. USA 2005, 102, 13767-13772.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 13767-13772
-
-
Clark, R.J.1
Fischer, H.2
Dempster, L.3
Daly, N.L.4
-
108
-
-
0036495674
-
Circular proteins - no end in sight.
-
Trabi, M., Craik, D.J., Circular proteins - no end in sight. Trends Biochem. Sci. 2002, 27, 132-138.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 132-138
-
-
Trabi, M.1
Craik, D.J.2
-
109
-
-
0033582991
-
Increased ring closing metathesis activity of ruthenium-based olefin metathesis catalysts coordinated with imidazolin-2-ylidene ligands.
-
Scholl, M., Trnka, T.M., Morgan, J.P., Grubbs, R.H., Increased ring closing metathesis activity of ruthenium-based olefin metathesis catalysts coordinated with imidazolin-2-ylidene ligands. Tetrahedron Lett. 1999, 40, 2247-2250.
-
(1999)
Tetrahedron Lett.
, vol.40
, pp. 2247-2250
-
-
Scholl, M.1
Trnka, T.M.2
Morgan, J.P.3
Grubbs, R.H.4
-
110
-
-
0033731476
-
Phage display for selection of novel binding peptides.
-
Sidhu, S.S., Lowman, H. B., Cunningham, B.J., A. Wells, J.A., Phage display for selection of novel binding peptides. Method. Enzymol. 2000, 328, 333-363.
-
(2000)
Method. Enzymol.
, vol.328
, pp. 333-363
-
-
Sidhu, S.S.1
Lowman, H.B.2
Cunningham, B.J.A.3
Wells, J.A.4
-
111
-
-
35548986989
-
From combinatorial chemistry to cancer-targeting peptides.
-
Aina, O.H., Liu, R., Sutcliffe, J.L., Marik, J. et al., From combinatorial chemistry to cancer-targeting peptides. Mol. Pharm. 2007, 4, 631-651.
-
(2007)
Mol. Pharm.
, vol.4
, pp. 631-651
-
-
Aina, O.H.1
Liu, R.2
Sutcliffe, J.L.3
Marik, J.4
-
112
-
-
79952202142
-
Identification of homing peptides using the in vivo phage display technology.
-
Rivinoja, A., Laakkonen, P., Identification of homing peptides using the in vivo phage display technology. Methods Mol. Biol. 2011, 683, 401-415.
-
(2011)
Methods Mol. Biol.
, vol.683
, pp. 401-415
-
-
Rivinoja, A.1
Laakkonen, P.2
-
113
-
-
84875451385
-
Peptide-based glioma-targeted drug delivery vector gHope2.
-
Eriste, E., Kurrikoff, K., Suhorutsenko, J., Oskolkov, N. et al., Peptide-based glioma-targeted drug delivery vector gHope2. Bioconjug. Chem. 2013, 24, 305-313.
-
(2013)
Bioconjug. Chem.
, vol.24
, pp. 305-313
-
-
Eriste, E.1
Kurrikoff, K.2
Suhorutsenko, J.3
Oskolkov, N.4
-
114
-
-
58149507967
-
Identification of nose-to-brain homing peptide through phage display.
-
Wan, X.M., Chen, Y.P., Xu, W.R., Yang, W.J. et al., Identification of nose-to-brain homing peptide through phage display. Peptides 2009, 30, 343-350.
-
(2009)
Peptides
, vol.30
, pp. 343-350
-
-
Wan, X.M.1
Chen, Y.P.2
Xu, W.R.3
Yang, W.J.4
-
115
-
-
84881316686
-
-
Development trends for peptide therapeutics. Peptide Therapeutics Foundation 2010 Report.
-
Reichert, J., Pechon, P., Tartar, A., Dunn, M.K., Development trends for peptide therapeutics. Peptide Therapeutics Foundation 2010 Report.
-
-
-
Reichert, J.1
Pechon, P.2
Tartar, A.3
Dunn, M.K.4
-
116
-
-
0037040959
-
Selective in vivo inhibition of mitogen-activated protein kinase activation using cell-permeable peptides.
-
Kelemen, B.R., Hsiao, K., Goueli, S.A., Selective in vivo inhibition of mitogen-activated protein kinase activation using cell-permeable peptides. J. Biol. Chem. 2002, 277, 8741-8748.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8741-8748
-
-
Kelemen, B.R.1
Hsiao, K.2
Goueli, S.A.3
-
117
-
-
11144353897
-
Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor.
-
Kalinichenko, V.V., Major, M.L., Wang, X., Petrovic, V. et al., Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. Genes Dev. 2004, 18, 830-850.
-
(2004)
Genes Dev.
, vol.18
, pp. 830-850
-
-
Kalinichenko, V.V.1
Major, M.L.2
Wang, X.3
Petrovic, V.4
-
118
-
-
19344365470
-
Treatment of terminal peritoneal carcinomatosis by a transducible p53-activating peptide.
-
Snyder, E.L., Meade, B.R., Saenz, C.C., Dowdy, S.F. et al., Treatment of terminal peritoneal carcinomatosis by a transducible p53-activating peptide. PLoS Biol. 2004, 2, e36.
-
(2004)
PLoS Biol.
, vol.2
-
-
Snyder, E.L.1
Meade, B.R.2
Saenz, C.C.3
Dowdy, S.F.4
-
119
-
-
0347895102
-
Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ.
-
Arnt, C.R., Chiorean, M.V., Heldebrant, M.P., Gores, G.J. et al., Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ. J. Biol. Chem 2002, 277, 44236-44423.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 44236-44423
-
-
Arnt, C.R.1
Chiorean, M.V.2
Heldebrant, M.P.3
Gores, G.J.4
-
120
-
-
21144437911
-
Rational design of shepherdin, a novel anticancer agent.
-
Plescia, J., Salz, W., Xia, F., Pennati, M. et al., Rational design of shepherdin, a novel anticancer agent. Cancer Cell 2005, 457-468.
-
(2005)
Cancer Cell
, pp. 457-468
-
-
Plescia, J.1
Salz, W.2
Xia, F.3
Pennati, M.4
-
121
-
-
38549104532
-
Effect of synthetic cell-penetrating peptides on TrkA activity in PC12 cells.
-
Hirose, M., Takatori, M., Kuroda, Y., Abe, M. et al., Effect of synthetic cell-penetrating peptides on TrkA activity in PC12 cells. J. Pharmacol. Sci. 2008, 106, 107-113.
-
(2008)
J. Pharmacol. Sci.
, vol.106
, pp. 107-113
-
-
Hirose, M.1
Takatori, M.2
Kuroda, Y.3
Abe, M.4
-
122
-
-
37549059610
-
A TAT-DEF-Elk-1 peptide regulates the cytonuclear trafficking of Elk-1 and controls cytoskeleton dynamics.
-
Lavaur, J., Bernard, F., Trifilieff, P., Pascoli, V. et al., A TAT-DEF-Elk-1 peptide regulates the cytonuclear trafficking of Elk-1 and controls cytoskeleton dynamics. J. Neurosci. 2007, 27, 14448-1458.
-
(2007)
J. Neurosci.
, vol.27
, pp. 14448-11458
-
-
Lavaur, J.1
Bernard, F.2
Trifilieff, P.3
Pascoli, V.4
-
123
-
-
4744355870
-
Introduction of an N-terminal peptide of S100C/A11 into human cells induces apoptotic cell death.
-
Makino, E., Sakaguchi, M., Iwatsuki, K., Huh, N-H., Introduction of an N-terminal peptide of S100C/A11 into human cells induces apoptotic cell death. J. Mol. Med. (Berl). 2004, 82, 612-620.
-
(2004)
J. Mol. Med. (Berl).
, vol.82
, pp. 612-620
-
-
Makino, E.1
Sakaguchi, M.2
Iwatsuki, K.3
Huh, N.-H.4
-
124
-
-
23944507859
-
Intracellular translocation of the decapeptide carboxyl terminal of Gi3a induces the dual phosphorylation of p42/p44 MAP kinases.
-
Jones, S., Farquhar, M., Martin, A., Howl, J., Intracellular translocation of the decapeptide carboxyl terminal of Gi3a induces the dual phosphorylation of p42/p44 MAP kinases. Biochim. Biophys. Acta 2005, 1745, 207-214.
-
(2005)
Biochim. Biophys. Acta
, vol.1745
, pp. 207-214
-
-
Jones, S.1
Farquhar, M.2
Martin, A.3
Howl, J.4
-
125
-
-
0346157097
-
Intracellular delivery of bioactive peptides to RBL-2H3 cells induces β-hexoseaminidase secretion and phospholipase D activation.
-
Howl, J., Jones, S., Farquhar, M., Intracellular delivery of bioactive peptides to RBL-2H3 cells induces β-hexoseaminidase secretion and phospholipase D activation. ChemBioChem 2003, 1312-1316.
-
(2003)
ChemBioChem
, pp. 1312-1316
-
-
Howl, J.1
Jones, S.2
Farquhar, M.3
-
126
-
-
33847384130
-
A sychnological cell penetrating peptide mimic of p21(WAF1/CIP1) is pro-apoptogenic.
-
Baker, R.D., Howl, J., Nicholl, I.D., A sychnological cell penetrating peptide mimic of p21(WAF1/CIP1) is pro-apoptogenic. Peptides 2007, 28, 731-470.
-
(2007)
Peptides
, vol.28
, pp. 731-470
-
-
Baker, R.D.1
Howl, J.2
Nicholl, I.D.3
-
127
-
-
34247171612
-
Functional cell permeable motifs within medically relevant proteins.
-
Low, W., Mortlock, A., Petrovska, L., Dottorini, T. et al., Functional cell permeable motifs within medically relevant proteins. J. Biotechnol. 2007, 129, 555-564.
-
(2007)
J. Biotechnol.
, vol.129
, pp. 555-564
-
-
Low, W.1
Mortlock, A.2
Petrovska, L.3
Dottorini, T.4
-
128
-
-
28844441296
-
Cell-penetrating mimics of agonist-activated G-protein coupled receptors.
-
Östlund, P., Kilk, K., Lindgren, M., Hällbrink, M. et al., Cell-penetrating mimics of agonist-activated G-protein coupled receptors. Int. J. Pept. Res. Ther. 2005, 11, 237-247.
-
(2005)
Int. J. Pept. Res. Ther.
, vol.11
, pp. 237-247
-
-
Östlund, P.1
Kilk, K.2
Lindgren, M.3
Hällbrink, M.4
|